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The map label for this gene is fimB [H]

Identifier: 157371111

GI number: 157371111

Start: 3150813

End: 3151409

Strand: Direct

Name: fimB [H]

Synonym: Spro_2871

Alternate gene names: 157371111

Gene position: 3150813-3151409 (Clockwise)

Preceding gene: 157371101

Following gene: 157371112

Centisome position: 57.83

GC content: 56.45

Gene sequence:

>597_bases
ATGCAAAAATCTCACAACCACCGCAAGCACCTGACCCGTACCGAGGTCACCCGCCTGCTGCAACAGGCCGCCGCCGGACG
AGCGCCCGAGCGAGACAGCTGCCTGATCTGGATGGGTTTCATTCACGGCTGCCGCGTTAGTGAGCTTAACGGCCTGCGCA
TGGCGGACCTGGATATGGAAAGCGGTTGCGTCTATATGAACCGCCTTAAAAACGGGCTATCCACCATCCATCCGCTGGAA
ACCACCGAGAAAAATCTACTGACCCGCTGGCTGGAAAAACGCCGGTCCTGTCGCAATCTGGAGGATGAAGAGTGGCTGTT
TCTGTCGCAGAAAGGCTACCGGCTGTCGCGCCAGCGCATTTATCGCATGTTGCAGGCTTACGGTAAGCAGGCCGGACTTG
ATGTGGACGCCCATCCGCACATGTTGCGCCATGCCTGTGGCTATGCGCTGGCGGATAATGGCGCCGATACCCGGGTGATC
CAGGACTATCTGGGACACCGTAATATTCAGCATACGGTGCTGTACACCGCGGCCAATGCCGGACGATTTAAACACCTGTG
GAAGGAGGAAAAAGAGGAGGAAAATGTAACAATTTGA

Upstream 100 bases:

>100_bases
CACCCAACCTGCACTATACTGCCCCTTGCATCGTCAATGATTGACGGACGACGCCAATGGCCGGCCTGTTGCCGGCCTTT
GTTTTTTTCGAGGAGAAGCA

Downstream 100 bases:

>100_bases
GTCAAACTGACAACTAAACTAGGAATATCCTGAAAAAAAGTCAATGTTTGTTTTGTGGTTTTTTTATCCTTACCTATAAC
TCTATTAATATCAACAAAAT

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MQKSHNHRKHLTRTEVTRLLQQAAAGRAPERDSCLIWMGFIHGCRVSELNGLRMADLDMESGCVYMNRLKNGLSTIHPLE
TTEKNLLTRWLEKRRSCRNLEDEEWLFLSQKGYRLSRQRIYRMLQAYGKQAGLDVDAHPHMLRHACGYALADNGADTRVI
QDYLGHRNIQHTVLYTAANAGRFKHLWKEEKEEENVTI

Sequences:

>Translated_198_residues
MQKSHNHRKHLTRTEVTRLLQQAAAGRAPERDSCLIWMGFIHGCRVSELNGLRMADLDMESGCVYMNRLKNGLSTIHPLE
TTEKNLLTRWLEKRRSCRNLEDEEWLFLSQKGYRLSRQRIYRMLQAYGKQAGLDVDAHPHMLRHACGYALADNGADTRVI
QDYLGHRNIQHTVLYTAANAGRFKHLWKEEKEEENVTI
>Mature_198_residues
MQKSHNHRKHLTRTEVTRLLQQAAAGRAPERDSCLIWMGFIHGCRVSELNGLRMADLDMESGCVYMNRLKNGLSTIHPLE
TTEKNLLTRWLEKRRSCRNLEDEEWLFLSQKGYRLSRQRIYRMLQAYGKQAGLDVDAHPHMLRHACGYALADNGADTRVI
QDYLGHRNIQHTVLYTAANAGRFKHLWKEEKEEENVTI

Specific function: FimB is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimB switches f

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1790767, Length=187, Percent_Identity=50.2673796791444, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1790768, Length=181, Percent_Identity=49.7237569060773, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1789261, Length=181, Percent_Identity=33.7016574585635, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1790244, Length=187, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 23072; Mature: 23072

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKSHNHRKHLTRTEVTRLLQQAAAGRAPERDSCLIWMGFIHGCRVSELNGLRMADLDME
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCCCCCCCCEEECCCCC
SGCVYMNRLKNGLSTIHPLETTEKNLLTRWLEKRRSCRNLEDEEWLFLSQKGYRLSRQRI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHH
YRMLQAYGKQAGLDVDAHPHMLRHACGYALADNGADTRVIQDYLGHRNIQHTVLYTAANA
HHHHHHHHHHCCCCCCCCHHHHHHHHCHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCC
GRFKHLWKEEKEEENVTI
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQKSHNHRKHLTRTEVTRLLQQAAAGRAPERDSCLIWMGFIHGCRVSELNGLRMADLDME
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCCCCCCCCEEECCCCC
SGCVYMNRLKNGLSTIHPLETTEKNLLTRWLEKRRSCRNLEDEEWLFLSQKGYRLSRQRI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHH
YRMLQAYGKQAGLDVDAHPHMLRHACGYALADNGADTRVIQDYLGHRNIQHTVLYTAANA
HHHHHHHHHHCCCCCCCCHHHHHHHHCHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCC
GRFKHLWKEEKEEENVTI
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]