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The map label for this gene is fabH [H]

Identifier: 157371109

GI number: 157371109

Start: 3148786

End: 3149793

Strand: Reverse

Name: fabH [H]

Synonym: Spro_2869

Alternate gene names: 157371109

Gene position: 3149793-3148786 (Counterclockwise)

Preceding gene: 157371110

Following gene: 157371108

Centisome position: 57.81

GC content: 60.42

Gene sequence:

>1008_bases
ATGACAACACAATCTTGTTCACCCACGTTGCTGCCGTTGAAAGTCATCGCCACGGGGGCAGCACTGCCACCCAACCGAGT
CGACTCCTCCGCGCTCGATAGCCTGCTGTGCAAGCCGACAGGCTACGTCGAGAAACGTTCCGGTATCAGCTACCGTTTTC
ACGCCAGCGATGATGCCAGCCAGGCTGAACTGGCCGTCGCCGCATTGCAGGATGCCTTAAACCGTTACGGGATCGACGCG
CAGTCGATAGATCTGCTGATTTCCGCGTCGGCGATTTCAGTACAGGCCCTGCCATGCACGGCGGCGCATATTCTTAAGGT
GGCCGGACTGGCACCGGGCACTGCCGGTTTCGATATCAACAGCAGCTGTGTCAGTTTTATCTCCGCCCTGCAGGTGGCCG
CCGGGCTGCTGAATGCCGGGACCTACCGGCGCATTGCTATTGTCTCAGCCGATTTGGCTTCTCGCGGCATTGACTGGGAG
CATGAAGAGTCCTCGCTGATTTTTGGCGACGGCGCGGCCTGCGCCATCGTCGAGCGTGGCGACGGCAGCAGCGGTATTTT
GGCCAGCCTGGTGGAGACCTATCCTGAAGGTAGCGAGCTGTGCGAGATACGTGCCGGGGGGACGCGGCGCAACCCGCGCG
CCGGTATGACAAACAGCGATTTCCTGTTCCATATGCAGGGCAAACAGCTGTTCCGCCAGGCGTCGGCACTGATCGAAGAT
TATCTTGCTCGTTTGCTGGCAGCCAGTGGCCTGACACTGGCGCAGATCGCGACGGTGGTGCCGCACCAGGCAAGTCACCT
GTCGCTCGAACATATGCGCAAGCGGCTGCATGTTCCCCCTGAGGCACTGGTGGATATTTATCGCTATCACGGTAATCAGG
TGGCGGCATCTATCCCCACGGCGTTACACGCTGCGGTTACCGGCGGGCGATTTAACCCAGGTAAGCCGGTGATGCTGATT
GGCACCGCCGCCGGGCTGTCACTTGCCGGCATGGTGCTGCTGCCATGA

Upstream 100 bases:

>100_bases
TGCGGGCACTTTGGGATTTAAAACCGGGGATGGCTCGGTGCTGTCACAGGATAGCGCCGGGAGATCGCTTTATGGATATG
CAGGTTAGTTAACAATAATA

Downstream 100 bases:

>100_bases
GGGTGTTGGTCACCGGAGCCACCAGCGGGCTGGGGCGTAACGCGGCACAGTGGCTGTTGGAAGCGGGCCATCAGGTTCAT
GCCACCGGGCGTGACAGTCG

Product: beta-ketoacyl-acyl-carrier-protein synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTTQSCSPTLLPLKVIATGAALPPNRVDSSALDSLLCKPTGYVEKRSGISYRFHASDDASQAELAVAALQDALNRYGIDA
QSIDLLISASAISVQALPCTAAHILKVAGLAPGTAGFDINSSCVSFISALQVAAGLLNAGTYRRIAIVSADLASRGIDWE
HEESSLIFGDGAACAIVERGDGSSGILASLVETYPEGSELCEIRAGGTRRNPRAGMTNSDFLFHMQGKQLFRQASALIED
YLARLLAASGLTLAQIATVVPHQASHLSLEHMRKRLHVPPEALVDIYRYHGNQVAASIPTALHAAVTGGRFNPGKPVMLI
GTAAGLSLAGMVLLP

Sequences:

>Translated_335_residues
MTTQSCSPTLLPLKVIATGAALPPNRVDSSALDSLLCKPTGYVEKRSGISYRFHASDDASQAELAVAALQDALNRYGIDA
QSIDLLISASAISVQALPCTAAHILKVAGLAPGTAGFDINSSCVSFISALQVAAGLLNAGTYRRIAIVSADLASRGIDWE
HEESSLIFGDGAACAIVERGDGSSGILASLVETYPEGSELCEIRAGGTRRNPRAGMTNSDFLFHMQGKQLFRQASALIED
YLARLLAASGLTLAQIATVVPHQASHLSLEHMRKRLHVPPEALVDIYRYHGNQVAASIPTALHAAVTGGRFNPGKPVMLI
GTAAGLSLAGMVLLP
>Mature_334_residues
TTQSCSPTLLPLKVIATGAALPPNRVDSSALDSLLCKPTGYVEKRSGISYRFHASDDASQAELAVAALQDALNRYGIDAQ
SIDLLISASAISVQALPCTAAHILKVAGLAPGTAGFDINSSCVSFISALQVAAGLLNAGTYRRIAIVSADLASRGIDWEH
EESSLIFGDGAACAIVERGDGSSGILASLVETYPEGSELCEIRAGGTRRNPRAGMTNSDFLFHMQGKQLFRQASALIEDY
LARLLAASGLTLAQIATVVPHQASHLSLEHMRKRLHVPPEALVDIYRYHGNQVAASIPTALHAAVTGGRFNPGKPVMLIG
TAAGLSLAGMVLLP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=316, Percent_Identity=27.8481012658228, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 35037; Mature: 34906

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQSCSPTLLPLKVIATGAALPPNRVDSSALDSLLCKPTGYVEKRSGISYRFHASDDAS
CCCCCCCCCEEHHHHEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCC
QAELAVAALQDALNRYGIDAQSIDLLISASAISVQALPCTAAHILKVAGLAPGTAGFDIN
HHHHHHHHHHHHHHHHCCCHHHEEEEEEECEEEEEECCCHHHHHHHHHCCCCCCCCCCCC
SSCVSFISALQVAAGLLNAGTYRRIAIVSADLASRGIDWEHEESSLIFGDGAACAIVERG
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHCCCCCCCCCCCEEEECCCEEEEEECC
DGSSGILASLVETYPEGSELCEIRAGGTRRNPRAGMTNSDFLFHMQGKQLFRQASALIED
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHH
YLARLLAASGLTLAQIATVVPHQASHLSLEHMRKRLHVPPEALVDIYRYHGNQVAASIPT
HHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCEEEHHHHH
ALHAAVTGGRFNPGKPVMLIGTAAGLSLAGMVLLP
HHHHHHCCCCCCCCCCEEEEEECCCHHHCCEEECC
>Mature Secondary Structure 
TTQSCSPTLLPLKVIATGAALPPNRVDSSALDSLLCKPTGYVEKRSGISYRFHASDDAS
CCCCCCCCEEHHHHEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCC
QAELAVAALQDALNRYGIDAQSIDLLISASAISVQALPCTAAHILKVAGLAPGTAGFDIN
HHHHHHHHHHHHHHHHCCCHHHEEEEEEECEEEEEECCCHHHHHHHHHCCCCCCCCCCCC
SSCVSFISALQVAAGLLNAGTYRRIAIVSADLASRGIDWEHEESSLIFGDGAACAIVERG
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHCCCCCCCCCCCEEEECCCEEEEEECC
DGSSGILASLVETYPEGSELCEIRAGGTRRNPRAGMTNSDFLFHMQGKQLFRQASALIED
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHH
YLARLLAASGLTLAQIATVVPHQASHLSLEHMRKRLHVPPEALVDIYRYHGNQVAASIPT
HHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCEEEHHHHH
ALHAAVTGGRFNPGKPVMLIGTAAGLSLAGMVLLP
HHHHHHCCCCCCCCCCEEEEEECCCHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA