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The map label for this gene is exuR [H]

Identifier: 157371090

GI number: 157371090

Start: 3128706

End: 3129707

Strand: Direct

Name: exuR [H]

Synonym: Spro_2850

Alternate gene names: 157371090

Gene position: 3128706-3129707 (Clockwise)

Preceding gene: 157371089

Following gene: 157371092

Centisome position: 57.42

GC content: 62.08

Gene sequence:

>1002_bases
ATGCGCACCATGCCGATTAAAAAAGTCACCTCTCACGATGTCGCCCGCGTGGCCGGCGTTTCACGCACCGTGGTTTCCCG
CGCCTTTTCCAATCAGGGCCGGGTATCGCAGAAAAACCGTGAGCTGGTGATGCGCGTCGCCAGCCAACTGGGCTACGCCC
CTGACGCCATCGCCCAGAGCCTGCACACCGGCAAAACCGGCTTTGTCGCGGTGGTGGTAAACCACTTTCATGACCTGTCC
GACCTGGAGTTTTTCGACCGTCTGGTGGAGCAGTTGCAAAACAGCAACCGGCAGGCGGTGATGATTCGGCTGGAAGGCAT
CGAAGATCCGGCCGGCTACCTGAAACAAACCATTTCCTATCACGTCGATTCTGCCGTGGTGTTCGCCGACCATATCAGCG
CCCGCGCCGCGAAAGATCTGTTTCGCGTCGCCACGCCGATTATGCTCAACGGCCTGGCAGGCGATGCCCTGTGCGATGCG
CTCAACGCCGATGAGGCCCCCAGCCTGCAACAATTGGCGGCGCTGATGGCGCAAAAGGGGCAACAACGGGTGGCGGTGCT
GGGCGGACGCAGCAGCGCCAAAGGGGAACAGCTGCGCCAACAGACCTTTTTAGCCCAGGCGGCGCAGCAGCAGTTGCAGA
TCGTGGCCCAGCTCAGCGGTGACTACAGCTACCTGAGCGGTTTCAAACTGGCACCGCAACTGCTGGCGGCACGGCCGGCC
CCGCAGGCGATCTTCTGTACCGCAGACTCCATGGCGATGGGGGTGATGGATTATATTCGTTTGCATACGTCGCTGCGGAT
CCCGCAGGACGTCGCGGTCTACGGCTTCGACGATATTCCGATGGCCGCCTGGCCGAGCTACCAACTGACCTCGGTGCGGC
GGGATATCAGTGCGATGATCGCCGCCATCGTGCAACTGATCGAACTGCGCAGCAGCAGCCCGCAGGCCGCGCCGCAGCAG
GTGACCATCCCCACCGAACTGGTGGTGCGTGCCTCCTGCTAA

Upstream 100 bases:

>100_bases
CGACTGGCACCGCAGGGGGAAACGGTGTTACCGAGCGGCATTCTGTGAGACCCTATGCCCGCTGCGCGACCCTACCGCAG
CGCCCCGTTTTCCGTTGAGT

Downstream 100 bases:

>100_bases
CCCCGCCTTTCAGCGGGTAGTAATAATCTCGGCATCGCGTAACTCCGGTGCTACCATGCCGGTTTGCCACAGCCAGTATT
GGATCGGGCCGGGGCAATTG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRTMPIKKVTSHDVARVAGVSRTVVSRAFSNQGRVSQKNRELVMRVASQLGYAPDAIAQSLHTGKTGFVAVVVNHFHDLS
DLEFFDRLVEQLQNSNRQAVMIRLEGIEDPAGYLKQTISYHVDSAVVFADHISARAAKDLFRVATPIMLNGLAGDALCDA
LNADEAPSLQQLAALMAQKGQQRVAVLGGRSSAKGEQLRQQTFLAQAAQQQLQIVAQLSGDYSYLSGFKLAPQLLAARPA
PQAIFCTADSMAMGVMDYIRLHTSLRIPQDVAVYGFDDIPMAAWPSYQLTSVRRDISAMIAAIVQLIELRSSSPQAAPQQ
VTIPTELVVRASC

Sequences:

>Translated_333_residues
MRTMPIKKVTSHDVARVAGVSRTVVSRAFSNQGRVSQKNRELVMRVASQLGYAPDAIAQSLHTGKTGFVAVVVNHFHDLS
DLEFFDRLVEQLQNSNRQAVMIRLEGIEDPAGYLKQTISYHVDSAVVFADHISARAAKDLFRVATPIMLNGLAGDALCDA
LNADEAPSLQQLAALMAQKGQQRVAVLGGRSSAKGEQLRQQTFLAQAAQQQLQIVAQLSGDYSYLSGFKLAPQLLAARPA
PQAIFCTADSMAMGVMDYIRLHTSLRIPQDVAVYGFDDIPMAAWPSYQLTSVRRDISAMIAAIVQLIELRSSSPQAAPQQ
VTIPTELVVRASC
>Mature_333_residues
MRTMPIKKVTSHDVARVAGVSRTVVSRAFSNQGRVSQKNRELVMRVASQLGYAPDAIAQSLHTGKTGFVAVVVNHFHDLS
DLEFFDRLVEQLQNSNRQAVMIRLEGIEDPAGYLKQTISYHVDSAVVFADHISARAAKDLFRVATPIMLNGLAGDALCDA
LNADEAPSLQQLAALMAQKGQQRVAVLGGRSSAKGEQLRQQTFLAQAAQQQLQIVAQLSGDYSYLSGFKLAPQLLAARPA
PQAIFCTADSMAMGVMDYIRLHTSLRIPQDVAVYGFDDIPMAAWPSYQLTSVRRDISAMIAAIVQLIELRSSSPQAAPQQ
VTIPTELVVRASC

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=25.6024096385542, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790369, Length=291, Percent_Identity=23.0240549828179, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788474, Length=303, Percent_Identity=27.0627062706271, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787948, Length=341, Percent_Identity=24.633431085044, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786540, Length=345, Percent_Identity=26.3768115942029, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1789456, Length=341, Percent_Identity=24.633431085044, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1789068, Length=302, Percent_Identity=25.4966887417219, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786268, Length=320, Percent_Identity=25.625, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787580, Length=338, Percent_Identity=24.2603550295858, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787906, Length=307, Percent_Identity=27.0358306188925, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789202, Length=304, Percent_Identity=26.6447368421053, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790689, Length=260, Percent_Identity=23.8461538461538, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790715, Length=307, Percent_Identity=20.5211726384365, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994940, Length=284, Percent_Identity=24.2957746478873, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36206; Mature: 36206

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTMPIKKVTSHDVARVAGVSRTVVSRAFSNQGRVSQKNRELVMRVASQLGYAPDAIAQS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
LHTGKTGFVAVVVNHFHDLSDLEFFDRLVEQLQNSNRQAVMIRLEGIEDPAGYLKQTISY
HHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHH
HVDSAVVFADHISARAAKDLFRVATPIMLNGLAGDALCDALNADEAPSLQQLAALMAQKG
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCC
QQRVAVLGGRSSAKGEQLRQQTFLAQAAQQQLQIVAQLSGDYSYLSGFKLAPQLLAARPA
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCCC
PQAIFCTADSMAMGVMDYIRLHTSLRIPQDVAVYGFDDIPMAAWPSYQLTSVRRDISAMI
CCEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
AAIVQLIELRSSSPQAAPQQVTIPTELVVRASC
HHHHHHHHHHCCCCCCCCCEEECCHHHEEECCC
>Mature Secondary Structure
MRTMPIKKVTSHDVARVAGVSRTVVSRAFSNQGRVSQKNRELVMRVASQLGYAPDAIAQS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
LHTGKTGFVAVVVNHFHDLSDLEFFDRLVEQLQNSNRQAVMIRLEGIEDPAGYLKQTISY
HHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHH
HVDSAVVFADHISARAAKDLFRVATPIMLNGLAGDALCDALNADEAPSLQQLAALMAQKG
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCC
QQRVAVLGGRSSAKGEQLRQQTFLAQAAQQQLQIVAQLSGDYSYLSGFKLAPQLLAARPA
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCCC
PQAIFCTADSMAMGVMDYIRLHTSLRIPQDVAVYGFDDIPMAAWPSYQLTSVRRDISAMI
CCEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
AAIVQLIELRSSSPQAAPQQVTIPTELVVRASC
HHHHHHHHHHCCCCCCCCCEEECCHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]