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The map label for this gene is yoaE [H]

Identifier: 157371052

GI number: 157371052

Start: 3092444

End: 3093988

Strand: Reverse

Name: yoaE [H]

Synonym: Spro_2812

Alternate gene names: 157371052

Gene position: 3093988-3092444 (Counterclockwise)

Preceding gene: 157371058

Following gene: 157371047

Centisome position: 56.78

GC content: 57.41

Gene sequence:

>1545_bases
ATGGAATTTCTAATGGACCCCTCAATTTGGGCTGGGTTACTGACACTGGTGGTATTGGAAATCGTACTGGGCATCGACAA
CCTGGTGTTTATCGCCATTCTGGCCGATAAGCTGCCGCCGAAGCAGCGCGATAAAGCGCGTATCCTCGGCTTGTCGCTGG
CGCTGTTTATGCGTCTTGGCCTGTTGTCGGTGATTTCCTGGATGGTGACGCTGACCACGCCGCTGTTTAGCGTCGGGGAG
TTCAGCTTCTCCGGTCGCGACCTGATCCTGTTGTTTGGTGGTGTGTTCCTGTTGTTCAAGGCCACCATGGAGCTGCACGA
ACGGCTGGAAGGGCAAACGCACCAGGATGGCGCCAACCGTGGCTACGCCAAATTCTGGGCGGTGGTGGTACAGATTGTGA
TCCTTGACGCCGTGTTCTCACTCGACGCGGTAATTACCGCCGTGGGCATGGTGAACGACCTGCCGGTTATGATGACCGCC
GTTGTCATCGCCATGGTGGTGATGCTGGTGGCTTCCAAACCGCTGACCAACTTCGTTAATGCGCATCCTACTATTGTGGT
GCTGTGCCTGAGCTTCCTGTTGATGATCGGCCTTAGCCTGATCGCCGAAGGCTTTGGTTTACATATTCCTAAAGGTTACC
TGTATGCCGCAATTGGTTTCTCGATCCTGATCGAGCTGTTTAACCAGATTGCCCGCCGTAACTTTATCAAACATCAGGCT
CATCGCCCGATGCGTGAACGCACCGCAGAGGCGATCATGCGCCTGATGGGGCAGCAGCGCGCACAGCAGACTGACGAAGC
GGCACCGCTACCGGTGAATGAAACCTTCGCCGAGGAAGAGCGTTATATGATCAGTGGCGTGTTAACGCTGGCTTCGCGTT
CTTTGCGTAGCGTGATGACGCCGCGCACTGATATTTCATGGGTGGATTGCGATCGTTCCCGTGAAGAGGTGCGTGAACAA
CTGCTGGATACGCCGCATAGCCTGTTCCCGGTGTGCCGCGACTCGCTGGATGAAATTATCGGCGTGGTGCGTGCCAAGGA
TCTGCTGGTGGCCGTAGAGCGGGGCGAGGATATCGCCGAGTTCGCCGCGCGTACGCCACCGATTGTGGTGCCGGACACTA
TGGACGTGATTAACCTGTTGGCGGTATTGCGCCGTGCCAAGGGACGTCTGGTGGTGGTCACCAACGAATTTGGTGTCGTG
CAGGGGCTGGTCACGCCACTGGACGTGCTGGAGGCGATTGCCGGTGAATTCCCGGACGAGGATGAAACGCCGGATATCGT
GGTGGAAGACGCCAGTTGGCTGGTGAAGGGCGGCGCCGACCTGCACTCACTGGAGCAGGCGCTGAACTGCGACGATCTGG
TCAGTCCGACGGCGGACTTCGCCACTCTGGCGGGGTTCCTGCTGTCCCACTACGGCCAAATGCCGGCGGTGGGTGAAACG
GTGGAGCTTAACCGACTGCGTTTCGAAGTCGTTGCCGTGTCCGAGTACCGCATTGAACTGGTGCGTATTACCAAAGTTGA
ACCTCACGACGAGGAACACCAGTAA

Upstream 100 bases:

>100_bases
CAATCCCGATATCTTGCTATTTCTGTCCGCGCCTTTGCTGCGTCGGCATCGTCACGCCTGAGCATCGCTCGGCCATCCTG
TCTTTTTTTCGGAGTCTGAT

Downstream 100 bases:

>100_bases
CCTACGGGCCGGAGGCATCACGCCTCCGGCTTGCTTTCCTGCTCCATCCGCCGTTCCTCCCGCTGATTCACCGCCCGCAA
CCGCGACTCATACTGCTGTA

Product: integral membrane protein TerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARILGLSLALFMRLGLLSVISWMVTLTTPLFSVGE
FSFSGRDLILLFGGVFLLFKATMELHERLEGQTHQDGANRGYAKFWAVVVQIVILDAVFSLDAVITAVGMVNDLPVMMTA
VVIAMVVMLVASKPLTNFVNAHPTIVVLCLSFLLMIGLSLIAEGFGLHIPKGYLYAAIGFSILIELFNQIARRNFIKHQA
HRPMRERTAEAIMRLMGQQRAQQTDEAAPLPVNETFAEEERYMISGVLTLASRSLRSVMTPRTDISWVDCDRSREEVREQ
LLDTPHSLFPVCRDSLDEIIGVVRAKDLLVAVERGEDIAEFAARTPPIVVPDTMDVINLLAVLRRAKGRLVVVTNEFGVV
QGLVTPLDVLEAIAGEFPDEDETPDIVVEDASWLVKGGADLHSLEQALNCDDLVSPTADFATLAGFLLSHYGQMPAVGET
VELNRLRFEVVAVSEYRIELVRITKVEPHDEEHQ

Sequences:

>Translated_514_residues
MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARILGLSLALFMRLGLLSVISWMVTLTTPLFSVGE
FSFSGRDLILLFGGVFLLFKATMELHERLEGQTHQDGANRGYAKFWAVVVQIVILDAVFSLDAVITAVGMVNDLPVMMTA
VVIAMVVMLVASKPLTNFVNAHPTIVVLCLSFLLMIGLSLIAEGFGLHIPKGYLYAAIGFSILIELFNQIARRNFIKHQA
HRPMRERTAEAIMRLMGQQRAQQTDEAAPLPVNETFAEEERYMISGVLTLASRSLRSVMTPRTDISWVDCDRSREEVREQ
LLDTPHSLFPVCRDSLDEIIGVVRAKDLLVAVERGEDIAEFAARTPPIVVPDTMDVINLLAVLRRAKGRLVVVTNEFGVV
QGLVTPLDVLEAIAGEFPDEDETPDIVVEDASWLVKGGADLHSLEQALNCDDLVSPTADFATLAGFLLSHYGQMPAVGET
VELNRLRFEVVAVSEYRIELVRITKVEPHDEEHQ
>Mature_514_residues
MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARILGLSLALFMRLGLLSVISWMVTLTTPLFSVGE
FSFSGRDLILLFGGVFLLFKATMELHERLEGQTHQDGANRGYAKFWAVVVQIVILDAVFSLDAVITAVGMVNDLPVMMTA
VVIAMVVMLVASKPLTNFVNAHPTIVVLCLSFLLMIGLSLIAEGFGLHIPKGYLYAAIGFSILIELFNQIARRNFIKHQA
HRPMRERTAEAIMRLMGQQRAQQTDEAAPLPVNETFAEEERYMISGVLTLASRSLRSVMTPRTDISWVDCDRSREEVREQ
LLDTPHSLFPVCRDSLDEIIGVVRAKDLLVAVERGEDIAEFAARTPPIVVPDTMDVINLLAVLRRAKGRLVVVTNEFGVV
QGLVTPLDVLEAIAGEFPDEDETPDIVVEDASWLVKGGADLHSLEQALNCDDLVSPTADFATLAGFLLSHYGQMPAVGET
VELNRLRFEVVAVSEYRIELVRITKVEPHDEEHQ

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=239, Percent_Identity=23.4309623430962, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1788119, Length=518, Percent_Identity=71.4285714285714, Blast_Score=734, Evalue=0.0,
Organism=Escherichia coli, GI87082033, Length=518, Percent_Identity=50.5791505791506, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI1789197, Length=232, Percent_Identity=48.2758620689655, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1790664, Length=233, Percent_Identity=29.1845493562232, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786879, Length=233, Percent_Identity=28.755364806867, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693175, Length=278, Percent_Identity=26.978417266187, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 56934; Mature: 56934

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARILGLSLALFMRLG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LLSVISWMVTLTTPLFSVGEFSFSGRDLILLFGGVFLLFKATMELHERLEGQTHQDGANR
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GYAKFWAVVVQIVILDAVFSLDAVITAVGMVNDLPVMMTAVVIAMVVMLVASKPLTNFVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHC
AHPTIVVLCLSFLLMIGLSLIAEGFGLHIPKGYLYAAIGFSILIELFNQIARRNFIKHQA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRPMRERTAEAIMRLMGQQRAQQTDEAAPLPVNETFAEEERYMISGVLTLASRSLRSVMT
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PRTDISWVDCDRSREEVREQLLDTPHSLFPVCRDSLDEIIGVVRAKDLLVAVERGEDIAE
CCCCCCEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FAARTPPIVVPDTMDVINLLAVLRRAKGRLVVVTNEFGVVQGLVTPLDVLEAIAGEFPDE
HHHCCCCEECCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
DETPDIVVEDASWLVKGGADLHSLEQALNCDDLVSPTADFATLAGFLLSHYGQMPAVGET
CCCCCEEEECCHHHHCCCCHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCC
VELNRLRFEVVAVSEYRIELVRITKVEPHDEEHQ
EEHHHEEEEEEEEEHHEEEEEEEEECCCCCCCCC
>Mature Secondary Structure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EEHHHEEEEEEEEEHHEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]