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The map label for this gene is pabB [H]

Identifier: 157371048

GI number: 157371048

Start: 3086593

End: 3087966

Strand: Direct

Name: pabB [H]

Synonym: Spro_2808

Alternate gene names: 157371048

Gene position: 3086593-3087966 (Clockwise)

Preceding gene: 157371045

Following gene: 157371049

Centisome position: 56.65

GC content: 58.08

Gene sequence:

>1374_bases
ATGAGCGCAACCGCACCGAATATTAAGTCTTTACCCTACACCCGCACCGCCCTGCTGGAGCTGTTTGCCCCACTGGCCTC
ACAGCCTTGGGCGATGTTGCTACATTCCGGTTTTGCCGAACACTCACATAACCGTTTCGATATTCTGGTGGCGCAACCCT
GTGCAACCCTGAGCACTCGTGGCCCCATTACCGAGATCCGTCGCGGTGAAGAGCATTGGACGTCGCCGGAAGATCCTTTC
CGCCTGATACAACAGCAGCTGGAACAGCTGAACCTGCACCCGCAGGTGGATGCCTGCTTGCCGTTCCAGGGCGGCGCCCT
CGGGTTGTTCGGTTACGATTTGGGTCGTCGGGTAGAAAAACTGCCTCAGTGGGCACAGGCAGATATCACGCTGCCGGATA
TGGCGGTCGGTATTTACGACTGGGCAGTGATAGCCGATCACCACCGACAGACGCTGACGTTACTCAGCTATGGTGATGGG
GAACAGCGCTGGCAGTGGCTCCGCAATCAGCAGCCTGCAGCCCGGCCTGCATTTGCCCTGACCAGCCCCTGGCAGGCCAA
TATGACGCGCCGGCAGTACGGTGAAAAGTTCCAGCGTATTCAGCATTACCTGCGCAGTGGCGACTGTTATCAAATCAATC
TGGCGCAACGTTTTGCTGCCGATTATCAGGGCGATGAATGGCAAGCCTTTCAGCAATTGAGCGCCAGCAATCGCGCCCCC
TTCTCTGCCTTCCTGCGTCTGCCGGAAAACGCCGTGCTGAGCGTTTCACCCGAGCGCTTTTTGTGGCTGGAAAACCAACA
TATTCAAACCCGCCCGATCAAAGGTACCCTGCCGCGGCTGGCCGATGCCGATCAGGATGCGCAGCAGGCACAACGCTTGG
CAAACTCCAGCAAAGACCGTGCGGAGAACCTGATGATTGTCGATTTACTGCGCAATGATATCGGCCGAGTTGCCGAACCG
GGCAGCGTGCAGGTTCCCGAACTGTTTGTGGTCGAACCCTTCCCGGCGGTACATCATCTGGTCAGCACCATCACCGCCAC
CCTGCCGCTACGCACTCCGGCAACCGAGCTGCTGCGCGCCTGCTTCCCGGGCGGTTCCATTACCGGGGCGCCCAAGGTAC
GAGCCATGGAAATTATTGAAGAGCTGGAGCCGCAGCGACGAAACGCCTACTGCGGCAGCATCGGATATATCAGTACCTGC
GGCACCATGGACACCAACATCACTATCCGCACCCTGATCACCGAAAACGGCCGCATTTACTGTTCCGCCGGTGGCGGCAT
CGTTGCCGACAGTCAGGAACAGGCGGAATATCAGGAAACCTTTGATAAAGTCGGCCGCATTCTGCCGCAATTGGGGGAGT
TTATCGCTTCATGA

Upstream 100 bases:

>100_bases
TGTGCTTATGCGCCTGATGCCAGAGCATGCGTCAGCCGGTTGAATATGGCAGAATAGCCGTCAGAAACCGCCGCCCCATC
AGTCAGGTTTATTGAGGCCC

Downstream 100 bases:

>100_bases
ACCCACCGACTTATCCCACCTCGCTGGCGGCCTTTATCAGCCGCTTTCAGCTGCAACTGCCACAGGCATCGCAGATTTCA
CATAACGTTCGGCCCGCAGC

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSATAPNIKSLPYTRTALLELFAPLASQPWAMLLHSGFAEHSHNRFDILVAQPCATLSTRGPITEIRRGEEHWTSPEDPF
RLIQQQLEQLNLHPQVDACLPFQGGALGLFGYDLGRRVEKLPQWAQADITLPDMAVGIYDWAVIADHHRQTLTLLSYGDG
EQRWQWLRNQQPAARPAFALTSPWQANMTRRQYGEKFQRIQHYLRSGDCYQINLAQRFAADYQGDEWQAFQQLSASNRAP
FSAFLRLPENAVLSVSPERFLWLENQHIQTRPIKGTLPRLADADQDAQQAQRLANSSKDRAENLMIVDLLRNDIGRVAEP
GSVQVPELFVVEPFPAVHHLVSTITATLPLRTPATELLRACFPGGSITGAPKVRAMEIIEELEPQRRNAYCGSIGYISTC
GTMDTNITIRTLITENGRIYCSAGGGIVADSQEQAEYQETFDKVGRILPQLGEFIAS

Sequences:

>Translated_457_residues
MSATAPNIKSLPYTRTALLELFAPLASQPWAMLLHSGFAEHSHNRFDILVAQPCATLSTRGPITEIRRGEEHWTSPEDPF
RLIQQQLEQLNLHPQVDACLPFQGGALGLFGYDLGRRVEKLPQWAQADITLPDMAVGIYDWAVIADHHRQTLTLLSYGDG
EQRWQWLRNQQPAARPAFALTSPWQANMTRRQYGEKFQRIQHYLRSGDCYQINLAQRFAADYQGDEWQAFQQLSASNRAP
FSAFLRLPENAVLSVSPERFLWLENQHIQTRPIKGTLPRLADADQDAQQAQRLANSSKDRAENLMIVDLLRNDIGRVAEP
GSVQVPELFVVEPFPAVHHLVSTITATLPLRTPATELLRACFPGGSITGAPKVRAMEIIEELEPQRRNAYCGSIGYISTC
GTMDTNITIRTLITENGRIYCSAGGGIVADSQEQAEYQETFDKVGRILPQLGEFIAS
>Mature_456_residues
SATAPNIKSLPYTRTALLELFAPLASQPWAMLLHSGFAEHSHNRFDILVAQPCATLSTRGPITEIRRGEEHWTSPEDPFR
LIQQQLEQLNLHPQVDACLPFQGGALGLFGYDLGRRVEKLPQWAQADITLPDMAVGIYDWAVIADHHRQTLTLLSYGDGE
QRWQWLRNQQPAARPAFALTSPWQANMTRRQYGEKFQRIQHYLRSGDCYQINLAQRFAADYQGDEWQAFQQLSASNRAPF
SAFLRLPENAVLSVSPERFLWLENQHIQTRPIKGTLPRLADADQDAQQAQRLANSSKDRAENLMIVDLLRNDIGRVAEPG
SVQVPELFVVEPFPAVHHLVSTITATLPLRTPATELLRACFPGGSITGAPKVRAMEIIEELEPQRRNAYCGSIGYISTCG
TMDTNITIRTLITENGRIYCSAGGGIVADSQEQAEYQETFDKVGRILPQLGEFIAS

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=451, Percent_Identity=66.0753880266075, Blast_Score=620, Evalue=1e-179,
Organism=Escherichia coli, GI1787518, Length=392, Percent_Identity=32.3979591836735, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1786809, Length=237, Percent_Identity=26.5822784810127, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87082077, Length=197, Percent_Identity=26.3959390862944, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=449, Percent_Identity=28.9532293986637, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=392, Percent_Identity=27.0408163265306, Blast_Score=137, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 51230; Mature: 51098

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATAPNIKSLPYTRTALLELFAPLASQPWAMLLHSGFAEHSHNRFDILVAQPCATLSTR
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHCCCC
GPITEIRRGEEHWTSPEDPFRLIQQQLEQLNLHPQVDACLPFQGGALGLFGYDLGRRVEK
CCHHHHHCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCEEEEHHHHHHHHHHH
LPQWAQADITLPDMAVGIYDWAVIADHHRQTLTLLSYGDGEQRWQWLRNQQPAARPAFAL
CCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCEEE
TSPWQANMTRRQYGEKFQRIQHYLRSGDCYQINLAQRFAADYQGDEWQAFQQLSASNRAP
CCCHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCCCCHHHHHHHHHCCCCCC
FSAFLRLPENAVLSVSPERFLWLENQHIQTRPIKGTLPRLADADQDAQQAQRLANSSKDR
HHHHHHCCCCCEEEECCHHEEEEECCCCEECCCCCCCCHHCCCCCHHHHHHHHHCCCHHH
AENLMIVDLLRNDIGRVAEPGSVQVPELFVVEPFPAVHHLVSTITATLPLRTPATELLRA
HHCEEHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHH
CFPGGSITGAPKVRAMEIIEELEPQRRNAYCGSIGYISTCGTMDTNITIRTLITENGRIY
HCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCEEECCCCCCCEEEEEEEECCCEEE
CSAGGGIVADSQEQAEYQETFDKVGRILPQLGEFIAS
EECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SATAPNIKSLPYTRTALLELFAPLASQPWAMLLHSGFAEHSHNRFDILVAQPCATLSTR
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHCCCC
GPITEIRRGEEHWTSPEDPFRLIQQQLEQLNLHPQVDACLPFQGGALGLFGYDLGRRVEK
CCHHHHHCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCEEEEHHHHHHHHHHH
LPQWAQADITLPDMAVGIYDWAVIADHHRQTLTLLSYGDGEQRWQWLRNQQPAARPAFAL
CCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCEEE
TSPWQANMTRRQYGEKFQRIQHYLRSGDCYQINLAQRFAADYQGDEWQAFQQLSASNRAP
CCCHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCCCCHHHHHHHHHCCCCCC
FSAFLRLPENAVLSVSPERFLWLENQHIQTRPIKGTLPRLADADQDAQQAQRLANSSKDR
HHHHHHCCCCCEEEECCHHEEEEECCCCEECCCCCCCCHHCCCCCHHHHHHHHHCCCHHH
AENLMIVDLLRNDIGRVAEPGSVQVPELFVVEPFPAVHHLVSTITATLPLRTPATELLRA
HHCEEHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHH
CFPGGSITGAPKVRAMEIIEELEPQRRNAYCGSIGYISTCGTMDTNITIRTLITENGRIY
HCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCEEECCCCCCCEEEEEEEECCCEEE
CSAGGGIVADSQEQAEYQETFDKVGRILPQLGEFIAS
EECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]