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The map label for this gene is msrB

Identifier: 157370967

GI number: 157370967

Start: 3003899

End: 3004312

Strand: Reverse

Name: msrB

Synonym: Spro_2727

Alternate gene names: 157370967

Gene position: 3004312-3003899 (Counterclockwise)

Preceding gene: 157370970

Following gene: 157370966

Centisome position: 55.14

GC content: 55.56

Gene sequence:

>414_bases
ATGGCTAAAGAGACAACCCCTGACCATCCGGCCACGGAACTGAATGAAATCCAACGTTATGTGACTCAGGAACGTGGTAC
CGAGGCGCCGTATTCCGGCAAATTGCTGCACAACAAGCGCGAGGGCGTGTACCATTGCCTGTGCTGCAACCAACCGCTGT
TCTACTCCGACAGCAAGTATGATTCCGGCTGTGGCTGGCCGAGCTTCTATCAGCCGGTTTCCGACGATGCTATTCGTTAT
CTTGATGATAATACGCATAATATGCATCGCGTTGAGATCCGCTGTGGGCATTGCGACGCACACCTGGGGCATGTCTTCCC
CGATGGCCCGCAGCCAACCGGTGAGCGTTTTTGCGTTAACTCGGCGTCGCTGAGCTTTACCGACGGTGAGAACGGCGACA
AAACCGCCGGCTGA

Upstream 100 bases:

>100_bases
GGCTACAGTTTAGGCCAAAAAGCGCTGCAGTGTTGTTAATTTTTTGTTATTATTACTCATTGTTTTCGTTGACATTATCC
ACATTCAGAGAAACGCACAA

Downstream 100 bases:

>100_bases
TGGATTATTCAGTGAGAAAAATCGATTCAGCTAATTATTCTTCCAAGAGTGAGGAAATGCTCTGATGGACGTAAAAGATC
TGATTGCCGCCATGACGCCG

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MAKETTPDHPATELNEIQRYVTQERGTEAPYSGKLLHNKREGVYHCLCCNQPLFYSDSKYDSGCGWPSFYQPVSDDAIRY
LDDNTHNMHRVEIRCGHCDAHLGHVFPDGPQPTGERFCVNSASLSFTDGENGDKTAG

Sequences:

>Translated_137_residues
MAKETTPDHPATELNEIQRYVTQERGTEAPYSGKLLHNKREGVYHCLCCNQPLFYSDSKYDSGCGWPSFYQPVSDDAIRY
LDDNTHNMHRVEIRCGHCDAHLGHVFPDGPQPTGERFCVNSASLSFTDGENGDKTAG
>Mature_136_residues
AKETTPDHPATELNEIQRYVTQERGTEAPYSGKLLHNKREGVYHCLCCNQPLFYSDSKYDSGCGWPSFYQPVSDDAIRYL
DDNTHNMHRVEIRCGHCDAHLGHVFPDGPQPTGERFCVNSASLSFTDGENGDKTAG

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI301336164, Length=124, Percent_Identity=50, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI301336162, Length=124, Percent_Identity=50, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI73089054, Length=124, Percent_Identity=50, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI37620216, Length=124, Percent_Identity=50, Blast_Score=146, Evalue=4e-36,
Organism=Homo sapiens, GI117606353, Length=122, Percent_Identity=51.6393442622951, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI1788077, Length=137, Percent_Identity=67.1532846715328, Blast_Score=209, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI17553450, Length=114, Percent_Identity=51.7543859649123, Blast_Score=122, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI115532676, Length=114, Percent_Identity=51.7543859649123, Blast_Score=122, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6319816, Length=132, Percent_Identity=43.1818181818182, Blast_Score=106, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24645799, Length=119, Percent_Identity=45.3781512605042, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI45553335, Length=118, Percent_Identity=45.7627118644068, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21356369, Length=118, Percent_Identity=45.7627118644068, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI221378662, Length=130, Percent_Identity=44.6153846153846, Blast_Score=119, Evalue=5e-28,
Organism=Drosophila melanogaster, GI221378664, Length=122, Percent_Identity=45.9016393442623, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24645801, Length=130, Percent_Identity=41.5384615384615, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24645804, Length=129, Percent_Identity=41.8604651162791, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_SERP5 (A8GFD8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478956.1
- ProteinModelPortal:   A8GFD8
- SMR:   A8GFD8
- STRING:   A8GFD8
- GeneID:   5606795
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2727
- eggNOG:   COG0229
- HOGENOM:   HBG715255
- OMA:   EVRCNHC
- ProtClustDB:   PRK00222
- BioCyc:   SPRO399741:SPRO_2727-MONOMER
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 15355; Mature: 15224

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKETTPDHPATELNEIQRYVTQERGTEAPYSGKLLHNKREGVYHCLCCNQPLFYSDSKY
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEEECCCCEECCCCCC
DSGCGWPSFYQPVSDDAIRYLDDNTHNMHRVEIRCGHCDAHLGHVFPDGPQPTGERFCVN
CCCCCCCHHCCCCCCCHHEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEC
SASLSFTDGENGDKTAG
CCEEEECCCCCCCCCCC
>Mature Secondary Structure 
AKETTPDHPATELNEIQRYVTQERGTEAPYSGKLLHNKREGVYHCLCCNQPLFYSDSKY
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEEECCCCEECCCCCC
DSGCGWPSFYQPVSDDAIRYLDDNTHNMHRVEIRCGHCDAHLGHVFPDGPQPTGERFCVN
CCCCCCCHHCCCCCCCHHEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEC
SASLSFTDGENGDKTAG
CCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA