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The map label for this gene is ychM [C]

Identifier: 157370916

GI number: 157370916

Start: 2945673

End: 2947376

Strand: Reverse

Name: ychM [C]

Synonym: Spro_2676

Alternate gene names: 157370916

Gene position: 2947376-2945673 (Counterclockwise)

Preceding gene: 157370920

Following gene: 157370914

Centisome position: 54.09

GC content: 57.39

Gene sequence:

>1704_bases
ATGCAGTGGAAATCTCTCCAGGCGCTTACGCCCGGTTTGACGCATTTATTAGGGTATCAACGCAGCTGGCTCAAACCGGA
CATTCGCGCCGGGCTTTCCGTCGCCGCCGTGGCCTTACCGGTAGCGATTGCCTACGCCGAATTGGCCGGAGTCAGCCCGA
TAGTGGGGTTATATTCCTGTATTTTACCCATGGTGGCCTATGCGTTTTTCGGCTCCTCACGCCAACTGATTGTCGGGCCG
GATGCGGCGACCTGTGCAGTGATTGCCGCCGTTGTGACCCCGTTGGCGGCGGGTAATATGGAACGCTACTGGCAATTGAC
CATTATGATGACGGCGATGATGGGCGCCTGGTGTCTGTTGGCCAGCCGCTTCAAACTGGGCGCCCTGGCCGATTTACTCT
CACGGCCGATACTCAGCGGTTTGCTGAACGGCGTGGCGATTACCATCATGGTCGATCAAATTGGCAAAGTGTTCGGATTT
GGCGTGCACCCGGCGCAGCTGATCGAACGTATTTACGCGTTGCCAGGCAACCTGATGCACAGTGATTGGCTGACCATGGC
GGTCTCGTTACTGGCTTTGGTTACGCTGATCGGGTTTAAAAAATGGCGCCCCAACTGGCCGGCACCGTTATTTGCCATTG
TTCTGGTCACGTTTATTACCTGGGCATGCAAGCTGCAACAGCATGGTGTGGTGACGGTCGGCGGCTTTAGTGATGTCTTG
CCGATAGTGCAGTGGCCGGATTTTCAACCGGGTTTGCTACGTGACATGGTGATCCCGGCGCTCAACCTGGCCGTCGTGAG
CTTTGTCAGCATGATGCTGACCGCCCGAAGCTTCGCGGCGAAAAACGGTTACGAGGTGAATGCGGATGCCGAGTTTCGTG
CGCTCGGGCTGGTGAATATTGTCTCGGCGCTGTCGCAGGGGTTCGCCATCAGCGGGGCGGATTCACGCACCGCGGTCAAT
GACGCCAACGGCGGCAAGAGCCAACTGGTGTCGATCATTGCGGCGGCGGTAATTGCCTTCGTGCTGTTGTTCCTGATGGC
CCCGCTACAGTTTATTCCGGTCGCGGGGTTGGGCGTGGTGCTGATGTATGCCGCCTGGTCGCTGCTGGATATTCGTGGCA
TCTGGACCCTGCGGCGACGCAATGCTCAGGCCTTCCGGCTGGCGATGTTTACCTTCCTTAGCGTATTGCTGGTGGGGGTG
ATCAGCGGCATTGGTCTGGCGGTTTTACTGGGTCTGATGCAGTTCCTGCGCACGGTGTTCCGCCCGACTGAGCAGCTGTT
GGGCGTCAATGAGGAAGGCATGATCCACTCGATGGGCAACAATAACGGCATTAAAGCGGTACCCGGTGTGATGATGTATC
GCTTCAACTCGCCGCTGACCTATTTCAACGTGGCGTATTTCAAACGGCGGATCCTGAACCTGGTGGACAGCACACCGTTC
CAGCCGCGTTGGGTGGTGGTGGACGCCGTTGCCAGCTTTACTCACGCCGATATCAGCGTACTGGCGGCGATCGACGAATT
GAAACGTGATTTGTTACAGCGTAACGTGAAGCTGGTGCTGGCAGGGCGCCGAACCGAGCTGACGCGCTGGTTCCGTATTA
ATCGGATGGGGCGCGACCGGGAATTGATCCTGGTACCGGATTTGTACCTGGCGCTAAAGTTGATCCAAAGTAAGGAACAG
GCGGAACCGACCGTGGCTCAATAA

Upstream 100 bases:

>100_bases
ATTGAGGTCGCGAGTTCGCGGCGGGCAGATTGCCAGCACGGCATTGGCATCGCATGATACGCGCAATAATAGCCGGATAA
TTTATAACGGAAAACAGTTT

Downstream 100 bases:

>100_bases
ACAAAAAGGCACGCCGAAGCGTGCCTTTTGGATTTCTACCGCAAGATTAGCTGCGCAGCAGCATATACAGACGGAACAGG
TAAATCAGCAACAGGGCCGA

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MQWKSLQALTPGLTHLLGYQRSWLKPDIRAGLSVAAVALPVAIAYAELAGVSPIVGLYSCILPMVAYAFFGSSRQLIVGP
DAATCAVIAAVVTPLAAGNMERYWQLTIMMTAMMGAWCLLASRFKLGALADLLSRPILSGLLNGVAITIMVDQIGKVFGF
GVHPAQLIERIYALPGNLMHSDWLTMAVSLLALVTLIGFKKWRPNWPAPLFAIVLVTFITWACKLQQHGVVTVGGFSDVL
PIVQWPDFQPGLLRDMVIPALNLAVVSFVSMMLTARSFAAKNGYEVNADAEFRALGLVNIVSALSQGFAISGADSRTAVN
DANGGKSQLVSIIAAAVIAFVLLFLMAPLQFIPVAGLGVVLMYAAWSLLDIRGIWTLRRRNAQAFRLAMFTFLSVLLVGV
ISGIGLAVLLGLMQFLRTVFRPTEQLLGVNEEGMIHSMGNNNGIKAVPGVMMYRFNSPLTYFNVAYFKRRILNLVDSTPF
QPRWVVVDAVASFTHADISVLAAIDELKRDLLQRNVKLVLAGRRTELTRWFRINRMGRDRELILVPDLYLALKLIQSKEQ
AEPTVAQ

Sequences:

>Translated_567_residues
MQWKSLQALTPGLTHLLGYQRSWLKPDIRAGLSVAAVALPVAIAYAELAGVSPIVGLYSCILPMVAYAFFGSSRQLIVGP
DAATCAVIAAVVTPLAAGNMERYWQLTIMMTAMMGAWCLLASRFKLGALADLLSRPILSGLLNGVAITIMVDQIGKVFGF
GVHPAQLIERIYALPGNLMHSDWLTMAVSLLALVTLIGFKKWRPNWPAPLFAIVLVTFITWACKLQQHGVVTVGGFSDVL
PIVQWPDFQPGLLRDMVIPALNLAVVSFVSMMLTARSFAAKNGYEVNADAEFRALGLVNIVSALSQGFAISGADSRTAVN
DANGGKSQLVSIIAAAVIAFVLLFLMAPLQFIPVAGLGVVLMYAAWSLLDIRGIWTLRRRNAQAFRLAMFTFLSVLLVGV
ISGIGLAVLLGLMQFLRTVFRPTEQLLGVNEEGMIHSMGNNNGIKAVPGVMMYRFNSPLTYFNVAYFKRRILNLVDSTPF
QPRWVVVDAVASFTHADISVLAAIDELKRDLLQRNVKLVLAGRRTELTRWFRINRMGRDRELILVPDLYLALKLIQSKEQ
AEPTVAQ
>Mature_567_residues
MQWKSLQALTPGLTHLLGYQRSWLKPDIRAGLSVAAVALPVAIAYAELAGVSPIVGLYSCILPMVAYAFFGSSRQLIVGP
DAATCAVIAAVVTPLAAGNMERYWQLTIMMTAMMGAWCLLASRFKLGALADLLSRPILSGLLNGVAITIMVDQIGKVFGF
GVHPAQLIERIYALPGNLMHSDWLTMAVSLLALVTLIGFKKWRPNWPAPLFAIVLVTFITWACKLQQHGVVTVGGFSDVL
PIVQWPDFQPGLLRDMVIPALNLAVVSFVSMMLTARSFAAKNGYEVNADAEFRALGLVNIVSALSQGFAISGADSRTAVN
DANGGKSQLVSIIAAAVIAFVLLFLMAPLQFIPVAGLGVVLMYAAWSLLDIRGIWTLRRRNAQAFRLAMFTFLSVLLVGV
ISGIGLAVLLGLMQFLRTVFRPTEQLLGVNEEGMIHSMGNNNGIKAVPGVMMYRFNSPLTYFNVAYFKRRILNLVDSTPF
QPRWVVVDAVASFTHADISVLAAIDELKRDLLQRNVKLVLAGRRTELTRWFRINRMGRDRELILVPDLYLALKLIQSKEQ
AEPTVAQ

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=482, Percent_Identity=26.1410788381743, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI39752683, Length=482, Percent_Identity=26.1410788381743, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI4557535, Length=506, Percent_Identity=25.4940711462451, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI269784651, Length=476, Percent_Identity=25.4201680672269, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI45827802, Length=431, Percent_Identity=26.6821345707657, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI4505697, Length=516, Percent_Identity=27.7131782945736, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI94721257, Length=478, Percent_Identity=25.7322175732218, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI94721259, Length=478, Percent_Identity=25.7322175732218, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI94721253, Length=478, Percent_Identity=25.7322175732218, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI94721255, Length=478, Percent_Identity=25.7322175732218, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI262206105, Length=569, Percent_Identity=24.2530755711775, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI262206075, Length=569, Percent_Identity=24.2530755711775, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI262206069, Length=569, Percent_Identity=24.2530755711775, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI262206063, Length=569, Percent_Identity=24.2530755711775, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI16418413, Length=512, Percent_Identity=24.609375, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI217272867, Length=512, Percent_Identity=24.609375, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI16418457, Length=498, Percent_Identity=26.7068273092369, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI301601599, Length=498, Percent_Identity=26.7068273092369, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI47131207, Length=520, Percent_Identity=25.9615384615385, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI20336272, Length=520, Percent_Identity=25.9615384615385, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI100913030, Length=496, Percent_Identity=24.5967741935484, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI301601602, Length=245, Percent_Identity=28.9795918367347, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI20336282, Length=583, Percent_Identity=20.4116638078902, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI16306483, Length=583, Percent_Identity=20.4116638078902, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI45827804, Length=245, Percent_Identity=24.4897959183673, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI65506789, Length=352, Percent_Identity=25.5681818181818, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI87081859, Length=431, Percent_Identity=22.737819025522, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17551690, Length=558, Percent_Identity=24.7311827956989, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI86564196, Length=596, Percent_Identity=23.993288590604, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI86565215, Length=482, Percent_Identity=25.3112033195021, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17566848, Length=563, Percent_Identity=24.866785079929, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI193203292, Length=487, Percent_Identity=23.6139630390144, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17562578, Length=499, Percent_Identity=23.6472945891784, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI86564876, Length=424, Percent_Identity=24.2924528301887, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325260, Length=570, Percent_Identity=22.4561403508772, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319771, Length=475, Percent_Identity=24, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6323121, Length=468, Percent_Identity=23.0769230769231, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24649801, Length=574, Percent_Identity=24.390243902439, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI85815873, Length=544, Percent_Identity=24.6323529411765, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21358229, Length=601, Percent_Identity=23.1281198003328, Blast_Score=109, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24666186, Length=535, Percent_Identity=23.5514018691589, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19922482, Length=534, Percent_Identity=23.9700374531835, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24647160, Length=433, Percent_Identity=23.3256351039261, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24663084, Length=557, Percent_Identity=24.9551166965889, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357695, Length=557, Percent_Identity=24.9551166965889, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355087, Length=433, Percent_Identity=23.3256351039261, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24651449, Length=622, Percent_Identity=22.1864951768489, Blast_Score=93, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 61957; Mature: 61957

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEEECCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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CEEECCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]