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The map label for this gene is mppA [H]

Identifier: 157370851

GI number: 157370851

Start: 2874315

End: 2875949

Strand: Reverse

Name: mppA [H]

Synonym: Spro_2611

Alternate gene names: 157370851

Gene position: 2875949-2874315 (Counterclockwise)

Preceding gene: 157370852

Following gene: 157370849

Centisome position: 52.78

GC content: 53.03

Gene sequence:

>1635_bases
ATGACGAGAAAAAAAATTCAACAGGGTTTTCGTTTGGCGCTGTGTGCCGTGGCGATTGGCGCAGGGCTGAGCAGCGCCAT
GGCGGCTCAGGTTCCCCCAGGTACTACGCTGGCGGAGAAACAGGAAATAGTTCGCCATATCAAAGATGAGCCGGCCTCAC
TCGATCCCATTAAAGCGGTTGGCCTGCCGGAAGCACAATTGGCGCGCGATCTGTTTGAAGGGCTGGTGAACCAGGATGCC
AACGGCAAGGTGATCCCCGGCGTCGCAACCCGCTGGCAAACCACCGATAACCAAACCTATATTTTCACCCTGCGTAAAGA
TGCGCGCTGGTCTAACGGTGACCCTGTCACGGCGAAAGACTTCGTTTACAGTTGGCAGCGGCTGGTTGAGCCGAAGAACT
TGTCACCTTTTGCCTGGTTTGCCCAGTTGGCCGGCATCCAAAACGCCGATGAGATCATTACCGGCAAGCTGCCTGCCGAT
AAGCTGGGCGTCACCGCGCTGGATGATTACACCTTCAAAGTGCAGTTGAACAAACCGGTGCCGTATTTTGTCAGCCTGAC
GGCCAACTTCAGCCTGTTCCCGGTCAACAAGGCGGTGGTAGAGAAATTTGGCAACGACTGGACCAAAGTCGGCAACCTGG
TCGGTAACGGCGCGTTTAAACTGCAGGAACGGGTAGTTAACGAGAAACTGGTACTGACGCCAAACGATCACTATTGGGAT
CATGCGCATACGGTGTTGACCAAAGTGACCTTTGTGCCGATCAACCAGGAATCCAACGCCACCAAGCGTTATCTGGCCGG
CGATATCGATATCACCGAGTCCTTCCCGAAAAACATGTACCAAAAACTGCTGAAAGACATCCCAAACCAGGTCTATACCC
CGGATCAGCTCGGCACCTATTATTATGCTTTTAATACCCAACGTGCGCCGACTAACGATGTGCGGGTGCGCAAGGCATTG
TCTTACGCTATCGATCGCAAGATTATCGCCGAAAAAGTGTTGGGGACCGGTGAAAAACCGGCTTACCACTTCACCCCGGA
TGTCACCGCCGGGTTTAAGCCGGAAGTGAGCCTGTTGCAACAGCAACCACAGGCCGAACTGGACGCCCAGGCCAAGGCGT
TGATGCAGGCGGCAGGTTATGGCCCGAACAATCCGCTGAAACTGACGCTGTTGTACAACACTTCGGAAAGCCATCAGAAA
ATTGCGATTGCCGTGGCTTCAATGTGGAAGAAAACGCTCGGTATTGACGTCAAGTTGCAAAATCAGGAATGGAAAACCTA
TATCGATAGCCGTAACACCGGCAATTTCGACGTGGTGCGCGCTTCGTGGGTCGGCGATTACAATGAAGCCTCGACCTTCC
TGTCGCTGTTAAGCTCAACCCACAGCGGAAATATCGCTAAATTCAAAAGTGCGGATTACGACAAACTGCTCGCGCAGGCC
AGCCGAGAAACCAGTCCGGCAGCCTTGACCACTGACTACAACAAACTTGAGCAGATCATCGCCGAACAGGCACCGATTGC
GCCAATTTATCAGTATACCAATGGCCGATTGATCAAACCCTGGGTGAAAGGCTACCCGATCACCAATCCGGAAGACGTGG
CGTACAGCCAGACGATGTATATTTTGAAGCATTGA

Upstream 100 bases:

>100_bases
GGCCCCCAGTTTTTACATCTTGTCCGCCGGGAACTCTAGGTGAGACTAATCTTGTGCTATAAGATAAAAAATTCAGATGG
TTAACGGGGGATAAATCAGA

Downstream 100 bases:

>100_bases
TATATTGCGATAGTCCCATGTGTTGCCATCAAACCCCGCGAGAGCGGGGTTTCTACTTAGGTGGCAGGACTATGGGGCAT
CAAACAATGCGCTACGGCCT

Product: extracellular solute-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MTRKKIQQGFRLALCAVAIGAGLSSAMAAQVPPGTTLAEKQEIVRHIKDEPASLDPIKAVGLPEAQLARDLFEGLVNQDA
NGKVIPGVATRWQTTDNQTYIFTLRKDARWSNGDPVTAKDFVYSWQRLVEPKNLSPFAWFAQLAGIQNADEIITGKLPAD
KLGVTALDDYTFKVQLNKPVPYFVSLTANFSLFPVNKAVVEKFGNDWTKVGNLVGNGAFKLQERVVNEKLVLTPNDHYWD
HAHTVLTKVTFVPINQESNATKRYLAGDIDITESFPKNMYQKLLKDIPNQVYTPDQLGTYYYAFNTQRAPTNDVRVRKAL
SYAIDRKIIAEKVLGTGEKPAYHFTPDVTAGFKPEVSLLQQQPQAELDAQAKALMQAAGYGPNNPLKLTLLYNTSESHQK
IAIAVASMWKKTLGIDVKLQNQEWKTYIDSRNTGNFDVVRASWVGDYNEASTFLSLLSSTHSGNIAKFKSADYDKLLAQA
SRETSPAALTTDYNKLEQIIAEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSQTMYILKH

Sequences:

>Translated_544_residues
MTRKKIQQGFRLALCAVAIGAGLSSAMAAQVPPGTTLAEKQEIVRHIKDEPASLDPIKAVGLPEAQLARDLFEGLVNQDA
NGKVIPGVATRWQTTDNQTYIFTLRKDARWSNGDPVTAKDFVYSWQRLVEPKNLSPFAWFAQLAGIQNADEIITGKLPAD
KLGVTALDDYTFKVQLNKPVPYFVSLTANFSLFPVNKAVVEKFGNDWTKVGNLVGNGAFKLQERVVNEKLVLTPNDHYWD
HAHTVLTKVTFVPINQESNATKRYLAGDIDITESFPKNMYQKLLKDIPNQVYTPDQLGTYYYAFNTQRAPTNDVRVRKAL
SYAIDRKIIAEKVLGTGEKPAYHFTPDVTAGFKPEVSLLQQQPQAELDAQAKALMQAAGYGPNNPLKLTLLYNTSESHQK
IAIAVASMWKKTLGIDVKLQNQEWKTYIDSRNTGNFDVVRASWVGDYNEASTFLSLLSSTHSGNIAKFKSADYDKLLAQA
SRETSPAALTTDYNKLEQIIAEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSQTMYILKH
>Mature_543_residues
TRKKIQQGFRLALCAVAIGAGLSSAMAAQVPPGTTLAEKQEIVRHIKDEPASLDPIKAVGLPEAQLARDLFEGLVNQDAN
GKVIPGVATRWQTTDNQTYIFTLRKDARWSNGDPVTAKDFVYSWQRLVEPKNLSPFAWFAQLAGIQNADEIITGKLPADK
LGVTALDDYTFKVQLNKPVPYFVSLTANFSLFPVNKAVVEKFGNDWTKVGNLVGNGAFKLQERVVNEKLVLTPNDHYWDH
AHTVLTKVTFVPINQESNATKRYLAGDIDITESFPKNMYQKLLKDIPNQVYTPDQLGTYYYAFNTQRAPTNDVRVRKALS
YAIDRKIIAEKVLGTGEKPAYHFTPDVTAGFKPEVSLLQQQPQAELDAQAKALMQAAGYGPNNPLKLTLLYNTSESHQKI
AIAVASMWKKTLGIDVKLQNQEWKTYIDSRNTGNFDVVRASWVGDYNEASTFLSLLSSTHSGNIAKFKSADYDKLLAQAS
RETSPAALTTDYNKLEQIIAEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSQTMYILKH

Specific function: Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=530, Percent_Identity=73.5849056603774, Blast_Score=822, Evalue=0.0,
Organism=Escherichia coli, GI1787495, Length=541, Percent_Identity=47.8743068391867, Blast_Score=506, Evalue=1e-144,
Organism=Escherichia coli, GI1789397, Length=518, Percent_Identity=43.2432432432432, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1787762, Length=539, Percent_Identity=24.860853432282, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1789887, Length=427, Percent_Identity=25.9953161592506, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789966, Length=480, Percent_Identity=23.9583333333333, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787551, Length=537, Percent_Identity=24.0223463687151, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787052, Length=515, Percent_Identity=21.1650485436893, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60645; Mature: 60513

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKKIQQGFRLALCAVAIGAGLSSAMAAQVPPGTTLAEKQEIVRHIKDEPASLDPIKAV
CCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GLPEAQLARDLFEGLVNQDANGKVIPGVATRWQTTDNQTYIFTLRKDARWSNGDPVTAKD
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCHHH
FVYSWQRLVEPKNLSPFAWFAQLAGIQNADEIITGKLPADKLGVTALDDYTFKVQLNKPV
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHEECCCCCHHCCCEEECCEEEEEEECCCC
PYFVSLTANFSLFPVNKAVVEKFGNDWTKVGNLVGNGAFKLQERVVNEKLVLTPNDHYWD
CEEEEEECCCEEEECCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCH
HAHTVLTKVTFVPINQESNATKRYLAGDIDITESFPKNMYQKLLKDIPNQVYTPDQLGTY
HHHHHHHEEEEEEECCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHCCHHCCCCHHHCCE
YYAFNTQRAPTNDVRVRKALSYAIDRKIIAEKVLGTGEKPAYHFTPDVTAGFKPEVSLLQ
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHH
QQPQAELDAQAKALMQAAGYGPNNPLKLTLLYNTSESHQKIAIAVASMWKKTLGIDVKLQ
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEC
NQEWKTYIDSRNTGNFDVVRASWVGDYNEASTFLSLLSSTHSGNIAKFKSADYDKLLAQA
CCHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
SRETSPAALTTDYNKLEQIIAEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSQTMY
CCCCCCCEEECCHHHHHHHHHHCCCCCCEEEECCCEEECHHHCCCCCCCCCCCCHHEEEE
ILKH
EEEC
>Mature Secondary Structure 
TRKKIQQGFRLALCAVAIGAGLSSAMAAQVPPGTTLAEKQEIVRHIKDEPASLDPIKAV
CHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GLPEAQLARDLFEGLVNQDANGKVIPGVATRWQTTDNQTYIFTLRKDARWSNGDPVTAKD
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCHHH
FVYSWQRLVEPKNLSPFAWFAQLAGIQNADEIITGKLPADKLGVTALDDYTFKVQLNKPV
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHEECCCCCHHCCCEEECCEEEEEEECCCC
PYFVSLTANFSLFPVNKAVVEKFGNDWTKVGNLVGNGAFKLQERVVNEKLVLTPNDHYWD
CEEEEEECCCEEEECCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCH
HAHTVLTKVTFVPINQESNATKRYLAGDIDITESFPKNMYQKLLKDIPNQVYTPDQLGTY
HHHHHHHEEEEEEECCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHCCHHCCCCHHHCCE
YYAFNTQRAPTNDVRVRKALSYAIDRKIIAEKVLGTGEKPAYHFTPDVTAGFKPEVSLLQ
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHH
QQPQAELDAQAKALMQAAGYGPNNPLKLTLLYNTSESHQKIAIAVASMWKKTLGIDVKLQ
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEC
NQEWKTYIDSRNTGNFDVVRASWVGDYNEASTFLSLLSSTHSGNIAKFKSADYDKLLAQA
CCHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
SRETSPAALTTDYNKLEQIIAEQAPIAPIYQYTNGRLIKPWVKGYPITNPEDVAYSQTMY
CCCCCCCEEECCHHHHHHHHHHCCCCCCEEEECCCEEECHHHCCCCCCCCCCCCHHEEEE
ILKH
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9495761; 9097039; 9278503 [H]