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The map label for this gene is fieF [H]

Identifier: 157370770

GI number: 157370770

Start: 2782441

End: 2783823

Strand: Reverse

Name: fieF [H]

Synonym: Spro_2530

Alternate gene names: 157370770

Gene position: 2783823-2782441 (Counterclockwise)

Preceding gene: 157370771

Following gene: 157370768

Centisome position: 51.09

GC content: 55.53

Gene sequence:

>1383_bases
ATGCAAAATGAAAAACAATCCGTTGCCAGAAATTCCATGATAGCCAGTGGGCTATTGGCAACCGGTAAATTTATTGCCGG
TATTTTTACCGGCAGTATTGGTCTTATTTCCGAAGGGATCCACTCTTTCACCGATTTTATCGCCACCAGCATTACCTGGC
TGGCGGTGCGTATCAGCGACAAACCGGCTGATGATGATCACCATTTTGGTCATGGCAAAGTCGAAAACCTGGCGGCTTTG
TTTGAAGTGCTGCTGCTGTTGGGCGCGGCGGGGTGGATTGTTTATGAGGCCGGCAAAAGCCTGTTGGGGGAGGCCCATGA
AATTGTCGCGGCTCCGGTGGTGATTGCCGTGCTGTTGATCTCGATTGTGGTCGACTTTTTCCGCGTCAGGGCGCTCAATC
GCGTGGCGAAGGCGACCGACAGTGCGGCGCTGGAAGCCGACGCACTGCATTTCTTCTCCGATATGCTTGCCTCCGCCGTG
GTGCTGTTAGGTATGGTCTTTGTGATGCTGGGCTTCACCCGCGCAGATGCCATCGCCGCGCTAATCGTCGCTTGTTTTAT
CGTAGTGGCAGCGGTGAAATTGGGTAAACGCTCGTTTGATTCGCTGATGGACACGGCACCGGCCGGTGCCAAGGAGGAGA
TCGGTGCTTTGCTGGAGTCCTTCCCGGCGATCCTGGCCACGGAAAATATCCGCATTCGCAACGCCGGCGCCATCTTGTTT
ATTGAGGTCACCGTCGCTGTCTGTCGCACTTTACCGCTGGAACGCATCAACGCGTTGAAGCAATCAATTGCCGAACGGCT
GGAGCAGCAGTATGCCCATGCCGAAGCCACGGTTATAGCTAATCCACAAACCCGCAGTGACGAAGACATGGCGACGCGTA
TCCGGGTGATCGCAGCCAACCACGGCGCGGTAGTACAAAATCTGGCGTTGCAGCAACTGCCGGAACGCATGTCGATAAGT
ATGGATCTGGCCGTGCCGGCCAGTGCCAACGTGGCGCAGGCGCATGAAATTGCCAGTGAGATTGAAACGCTGTTACGGCA
GGCGATTGGTGAAGATACGGAGATCGAAACTCATCTGGAACCCCAGACGAATCACTGGATCGCCAGCGAAGATGTAGCGC
CGGAGCAACTGGCGAGCATTCGCCAGATATTGGAAACCACGGTGGAAAAAGGCGAGATGGTGCAGGACGTTCATAACATC
CGCGCACGTAAAACCGCTGGCGGCATTATCGTCAATTTCCATTGTCGGGTTTCCCCGGCGGCTTCTATCGCGTCGGCGCA
TGCGGCGGTAGACAGCATAGAGCGCCAGTTACGTGCGCTTTACCCGAGTATCTCGCGGGCGGTAGGGCATGTGGAACCGA
TAAAGCCCAAATCGGTCGTCTGA

Upstream 100 bases:

>100_bases
AATACTGACATTCTCGGGTACTATGCTGCTGGTTGCCTTTGTCTGGCAATGCTCTACTAAAATAAAAAAATGAATTGCCC
ATTTGAATGTGAGCCGTAAT

Downstream 100 bases:

>100_bases
GTCCGGCAGCGGAGCCTCCTGGAAAGGCCGCCCGCGGGCGGCCTGTAAAGGTTAGTCCAGATTCAGTCGTGCAGTGAGGG
TGGAAATCTCACTGCGCCAT

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MQNEKQSVARNSMIASGLLATGKFIAGIFTGSIGLISEGIHSFTDFIATSITWLAVRISDKPADDDHHFGHGKVENLAAL
FEVLLLLGAAGWIVYEAGKSLLGEAHEIVAAPVVIAVLLISIVVDFFRVRALNRVAKATDSAALEADALHFFSDMLASAV
VLLGMVFVMLGFTRADAIAALIVACFIVVAAVKLGKRSFDSLMDTAPAGAKEEIGALLESFPAILATENIRIRNAGAILF
IEVTVAVCRTLPLERINALKQSIAERLEQQYAHAEATVIANPQTRSDEDMATRIRVIAANHGAVVQNLALQQLPERMSIS
MDLAVPASANVAQAHEIASEIETLLRQAIGEDTEIETHLEPQTNHWIASEDVAPEQLASIRQILETTVEKGEMVQDVHNI
RARKTAGGIIVNFHCRVSPAASIASAHAAVDSIERQLRALYPSISRAVGHVEPIKPKSVV

Sequences:

>Translated_460_residues
MQNEKQSVARNSMIASGLLATGKFIAGIFTGSIGLISEGIHSFTDFIATSITWLAVRISDKPADDDHHFGHGKVENLAAL
FEVLLLLGAAGWIVYEAGKSLLGEAHEIVAAPVVIAVLLISIVVDFFRVRALNRVAKATDSAALEADALHFFSDMLASAV
VLLGMVFVMLGFTRADAIAALIVACFIVVAAVKLGKRSFDSLMDTAPAGAKEEIGALLESFPAILATENIRIRNAGAILF
IEVTVAVCRTLPLERINALKQSIAERLEQQYAHAEATVIANPQTRSDEDMATRIRVIAANHGAVVQNLALQQLPERMSIS
MDLAVPASANVAQAHEIASEIETLLRQAIGEDTEIETHLEPQTNHWIASEDVAPEQLASIRQILETTVEKGEMVQDVHNI
RARKTAGGIIVNFHCRVSPAASIASAHAAVDSIERQLRALYPSISRAVGHVEPIKPKSVV
>Mature_460_residues
MQNEKQSVARNSMIASGLLATGKFIAGIFTGSIGLISEGIHSFTDFIATSITWLAVRISDKPADDDHHFGHGKVENLAAL
FEVLLLLGAAGWIVYEAGKSLLGEAHEIVAAPVVIAVLLISIVVDFFRVRALNRVAKATDSAALEADALHFFSDMLASAV
VLLGMVFVMLGFTRADAIAALIVACFIVVAAVKLGKRSFDSLMDTAPAGAKEEIGALLESFPAILATENIRIRNAGAILF
IEVTVAVCRTLPLERINALKQSIAERLEQQYAHAEATVIANPQTRSDEDMATRIRVIAANHGAVVQNLALQQLPERMSIS
MDLAVPASANVAQAHEIASEIETLLRQAIGEDTEIETHLEPQTNHWIASEDVAPEQLASIRQILETTVEKGEMVQDVHNI
RARKTAGGIIVNFHCRVSPAASIASAHAAVDSIERQLRALYPSISRAVGHVEPIKPKSVV

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790349, Length=271, Percent_Identity=29.1512915129151, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 49351; Mature: 49351

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNEKQSVARNSMIASGLLATGKFIAGIFTGSIGLISEGIHSFTDFIATSITWLAVRISD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEECC
KPADDDHHFGHGKVENLAALFEVLLLLGAAGWIVYEAGKSLLGEAHEIVAAPVVIAVLLI
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIVVDFFRVRALNRVAKATDSAALEADALHFFSDMLASAVVLLGMVFVMLGFTRADAIAA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIVACFIVVAAVKLGKRSFDSLMDTAPAGAKEEIGALLESFPAILATENIRIRNAGAILF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCEEEE
IEVTVAVCRTLPLERINALKQSIAERLEQQYAHAEATVIANPQTRSDEDMATRIRVIAAN
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHEECC
HGAVVQNLALQQLPERMSISMDLAVPASANVAQAHEIASEIETLLRQAIGEDTEIETHLE
CCHHHHHHHHHHCHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
PQTNHWIASEDVAPEQLASIRQILETTVEKGEMVQDVHNIRARKTAGGIIVNFHCRVSPA
CCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHH
ASIASAHAAVDSIERQLRALYPSISRAVGHVEPIKPKSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQNEKQSVARNSMIASGLLATGKFIAGIFTGSIGLISEGIHSFTDFIATSITWLAVRISD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEECC
KPADDDHHFGHGKVENLAALFEVLLLLGAAGWIVYEAGKSLLGEAHEIVAAPVVIAVLLI
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIVVDFFRVRALNRVAKATDSAALEADALHFFSDMLASAVVLLGMVFVMLGFTRADAIAA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIVACFIVVAAVKLGKRSFDSLMDTAPAGAKEEIGALLESFPAILATENIRIRNAGAILF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCEEEE
IEVTVAVCRTLPLERINALKQSIAERLEQQYAHAEATVIANPQTRSDEDMATRIRVIAAN
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHEECC
HGAVVQNLALQQLPERMSISMDLAVPASANVAQAHEIASEIETLLRQAIGEDTEIETHLE
CCHHHHHHHHHHCHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCC
PQTNHWIASEDVAPEQLASIRQILETTVEKGEMVQDVHNIRARKTAGGIIVNFHCRVSPA
CCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHH
ASIASAHAAVDSIERQLRALYPSISRAVGHVEPIKPKSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA