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The map label for this gene is dsdA

Identifier: 157370755

GI number: 157370755

Start: 2761544

End: 2762881

Strand: Reverse

Name: dsdA

Synonym: Spro_2515

Alternate gene names: 157370755

Gene position: 2762881-2761544 (Counterclockwise)

Preceding gene: 157370756

Following gene: 157370752

Centisome position: 50.71

GC content: 58.97

Gene sequence:

>1338_bases
ATGGAAAAGACACAGATTCAGCAGCTGGTTAAGCAATTCCCGCTGGTGCAGGAACTGATCGAACTAAACCCGGTAACCTG
GTTCAACCCACGAGCGACCACTTTGCAGGCCGGGTTGCCGTTCGTTGGGCTGGATGCCGCAGACGTGGCCGACGCAGAAC
AACGTCTGGCGCGTTTCGCCCCTTATCTGAGTGCCGCCTTCCCGGAAACCCGAGCCGCAAATGGCGTGATTGAATCTGAA
GTGGTGGCGCTTCCTGCAATGCAAACTGCGCTCGACCAACGTTATGGTTTGTCGCTAGCCGGCCGGTTGCTGTTGAAAAA
GGACAGCCATCTGCCAATTTCCGGTTCGATCAAGGCGCGCGGCGGTATCTACGAGGTGCTGGCGCATGCGGAAAAACTGG
CGCTGGCAGCGGGGCTGCTGCAGCTGACGGACGACTACGCCAAGCTGTTCTCGGCGGAATTTCGCGAATTCTTTGGCGGT
TACCGCATTGCCGTCGGCTCGACCGGCAATCTGGGGATGTCGATCGGTATTATCAGCGCCCGGCTGGGGTTTAGCGTGAG
CGTGCATATGTCGGCGGACGCTCGCGAATGGAAAAAACAGAAGCTGCGTGACAATGGCGTCAACGTGGTGGAGTACGAAC
AGGATTATGGCGTTGCCGTTGAACAGGGCCGTTTGCAGGCGGCGAGCGATCCGCGCTGTTTCTTTATCGATGACGAGAAT
TCACAGACGCTGTTTCTGGGCTATGCCGTGGCCGGTGGCCGCCTGAGACGTCAGTTTGCCGAAAGTGGCGTCCAGGTTGA
TGCTCAGCACCCGTTGTTTGTTTATTTGCCTTGCGGCGTTGGCGGCGGGCCTGGCGGGGTGGCCTTTGGGCTGAAACTGG
CCTTTGGCGACCATGTACACTGCATCTTTGCCGAACCGACGCATTCACCTTGCATGTTGCTTGGTGTGCATACCGGCCTG
CACGATGGTATCGCGGTACAGGATCTGGGCATTGATAACCAGACCGCGGCGGACGGGCTGGCGGTAGGGCGCGCATCCGG
CTTCGTCGGCCGGGCTATGGAGCGCCTGCTCTCCGGCTTCTACACCCTCAGCGACCGCGAGATGTTTGCACTGCTGGGGT
TATTGGACAGTCATGAGCATATTCAGCTAGAACCTTCGGCATTGGCGGGAATGCCGGGACCGTGGCGCGTGACGGCTGAC
ACTGAGTGGTTGGCGGCTCAGGGTTTGAATGAGCAACAAATGAAAAATGCCACCCACCTGGTGTGGGCGACCGGTGGCGG
CATGGTGCCTGAGGCGGAAATGGCCAAGTACCTGGCCAACGCACGCCAATCGATTTAG

Upstream 100 bases:

>100_bases
TGCATCAATCCTGCTCACGCAAGGCTCAAATTTTATCATTTGTCAGCCTGGGGAAATCGCTGCACCCTAGAGCTAACCTT
ATGCAGCGCAGAGAACAACC

Downstream 100 bases:

>100_bases
TGGTTTAGTAGCGAAAGTTCCTGTGAGCCTTCGAGCAGGATCGGCAGGATACGTTCGGTCAGTTCGCTCAGCGGGACATG
GCCGGCCTGCACCCCAACGT

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MEKTQIQQLVKQFPLVQELIELNPVTWFNPRATTLQAGLPFVGLDAADVADAEQRLARFAPYLSAAFPETRAANGVIESE
VVALPAMQTALDQRYGLSLAGRLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALAAGLLQLTDDYAKLFSAEFREFFGG
YRIAVGSTGNLGMSIGIISARLGFSVSVHMSADAREWKKQKLRDNGVNVVEYEQDYGVAVEQGRLQAASDPRCFFIDDEN
SQTLFLGYAVAGGRLRRQFAESGVQVDAQHPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCIFAEPTHSPCMLLGVHTGL
HDGIAVQDLGIDNQTAADGLAVGRASGFVGRAMERLLSGFYTLSDREMFALLGLLDSHEHIQLEPSALAGMPGPWRVTAD
TEWLAAQGLNEQQMKNATHLVWATGGGMVPEAEMAKYLANARQSI

Sequences:

>Translated_445_residues
MEKTQIQQLVKQFPLVQELIELNPVTWFNPRATTLQAGLPFVGLDAADVADAEQRLARFAPYLSAAFPETRAANGVIESE
VVALPAMQTALDQRYGLSLAGRLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALAAGLLQLTDDYAKLFSAEFREFFGG
YRIAVGSTGNLGMSIGIISARLGFSVSVHMSADAREWKKQKLRDNGVNVVEYEQDYGVAVEQGRLQAASDPRCFFIDDEN
SQTLFLGYAVAGGRLRRQFAESGVQVDAQHPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCIFAEPTHSPCMLLGVHTGL
HDGIAVQDLGIDNQTAADGLAVGRASGFVGRAMERLLSGFYTLSDREMFALLGLLDSHEHIQLEPSALAGMPGPWRVTAD
TEWLAAQGLNEQQMKNATHLVWATGGGMVPEAEMAKYLANARQSI
>Mature_445_residues
MEKTQIQQLVKQFPLVQELIELNPVTWFNPRATTLQAGLPFVGLDAADVADAEQRLARFAPYLSAAFPETRAANGVIESE
VVALPAMQTALDQRYGLSLAGRLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALAAGLLQLTDDYAKLFSAEFREFFGG
YRIAVGSTGNLGMSIGIISARLGFSVSVHMSADAREWKKQKLRDNGVNVVEYEQDYGVAVEQGRLQAASDPRCFFIDDEN
SQTLFLGYAVAGGRLRRQFAESGVQVDAQHPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCIFAEPTHSPCMLLGVHTGL
HDGIAVQDLGIDNQTAADGLAVGRASGFVGRAMERLLSGFYTLSDREMFALLGLLDSHEHIQLEPSALAGMPGPWRVTAD
TEWLAAQGLNEQQMKNATHLVWATGGGMVPEAEMAKYLANARQSI

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=442, Percent_Identity=71.7194570135747, Blast_Score=639, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_SERP5 (A8GES6)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478744.1
- ProteinModelPortal:   A8GES6
- STRING:   A8GES6
- GeneID:   5603827
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2515
- eggNOG:   COG3048
- HOGENOM:   HBG288722
- OMA:   WKKDLLR
- ProtClustDB:   PRK02991
- BioCyc:   SPRO399741:SPRO_2515-MONOMER
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 47955; Mature: 47955

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTQIQQLVKQFPLVQELIELNPVTWFNPRATTLQAGLPFVGLDAADVADAEQRLARFA
CCHHHHHHHHHHCHHHHHHHHCCCCEEECCCCCEEECCCCEEECCHHHHHHHHHHHHHHH
PYLSAAFPETRAANGVIESEVVALPAMQTALDQRYGLSLAGRLLLKKDSHLPISGSIKAR
HHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCCCCCCCCC
GGIYEVLAHAEKLALAAGLLQLTDDYAKLFSAEFREFFGGYRIAVGSTGNLGMSIGIISA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEE
RLGFSVSVHMSADAREWKKQKLRDNGVNVVEYEQDYGVAVEQGRLQAASDPRCFFIDDEN
ECCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCEEEECCCEECCCCCEEEEEECCC
SQTLFLGYAVAGGRLRRQFAESGVQVDAQHPLFVYLPCGVGGGPGGVAFGLKLAFGDHVH
CCEEEEEEEECCHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCEEE
CIFAEPTHSPCMLLGVHTGLHDGIAVQDLGIDNQTAADGLAVGRASGFVGRAMERLLSGF
EEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHH
YTLSDREMFALLGLLDSHEHIQLEPSALAGMPGPWRVTADTEWLAAQGLNEQQMKNATHL
EECCCCHHHHHHHHHCCCCCEEECHHHHCCCCCCEEEECCCHHHHHCCCCHHHHCCCEEE
VWATGGGMVPEAEMAKYLANARQSI
EEECCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKTQIQQLVKQFPLVQELIELNPVTWFNPRATTLQAGLPFVGLDAADVADAEQRLARFA
CCHHHHHHHHHHCHHHHHHHHCCCCEEECCCCCEEECCCCEEECCHHHHHHHHHHHHHHH
PYLSAAFPETRAANGVIESEVVALPAMQTALDQRYGLSLAGRLLLKKDSHLPISGSIKAR
HHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCCCCCCCCC
GGIYEVLAHAEKLALAAGLLQLTDDYAKLFSAEFREFFGGYRIAVGSTGNLGMSIGIISA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEE
RLGFSVSVHMSADAREWKKQKLRDNGVNVVEYEQDYGVAVEQGRLQAASDPRCFFIDDEN
ECCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCEEEECCCEECCCCCEEEEEECCC
SQTLFLGYAVAGGRLRRQFAESGVQVDAQHPLFVYLPCGVGGGPGGVAFGLKLAFGDHVH
CCEEEEEEEECCHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCEEE
CIFAEPTHSPCMLLGVHTGLHDGIAVQDLGIDNQTAADGLAVGRASGFVGRAMERLLSGF
EEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHH
YTLSDREMFALLGLLDSHEHIQLEPSALAGMPGPWRVTADTEWLAAQGLNEQQMKNATHL
EECCCCHHHHHHHHHCCCCCEEECHHHHCCCCCCEEEECCCHHHHHCCCCHHHHCCCEEE
VWATGGGMVPEAEMAKYLANARQSI
EEECCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA