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The map label for this gene is ycjZ [C]

Identifier: 157370695

GI number: 157370695

Start: 2689145

End: 2690032

Strand: Reverse

Name: ycjZ [C]

Synonym: Spro_2455

Alternate gene names: 157370695

Gene position: 2690032-2689145 (Counterclockwise)

Preceding gene: 157370699

Following gene: 157370692

Centisome position: 49.37

GC content: 52.25

Gene sequence:

>888_bases
ATGAAACGCAACCTGAATGACCTGCTTTATTTTGTTACGGTCGCACGTGAAAGCAGCTTTACCCGCGCGGCGGCACAATT
GGGCGTCACTCAACCGGCTCTGAGCCAGGCGATTTCCGCACTTGAAGAACGGATGCAAATTCGCCTACTGACGCGTACCA
CCCGTAGTGTGTCACCGACTTCCGCTGGAGAACGATTGTTACTGGCTATAGGCAATCGTATCGATGAGATTGAAGCCGAG
CTGGATATGCTGACGGAGCTGCGCGATAAGCCGGCGGGTAGGGTCCGCATCACCTGCGGGCCAGACGTTTTACACAGCAC
GCTGTTGCCAAAACTGTCGCCCCTGTTGCGAGAGTACCCGGACATAAATATCGAATTCGACGCCAATCATGGTTTCCGCG
ACATTGTGGCAGACCGTTTTGATGCGGGCGTTCGGCTGGGTGACACCATTGATAAAGACATGATAGCCGTTCCGATTGGC
CCCAAATTACGCATGGCTGTAGTGGCAGCACCGGACTACTTTTCACGTTACCCGATCCCCAATACTCCCCACGAATTGAC
GCAACACCTGTGCATAAATCAGCGAATGGTCAGGTCTGGCGGGCTGTATGTCTGGGATTTTGATCAGGATGGTGGGGATC
TTAATGTGCGCGTCAGCGGACAACTCATTTTCAATACTTCTGTACATATTGTTGATGCCGCGCTTGCAGGGTTGGGGATT
GCATTTTTGCCAGAAGAAGAATTTGGAAAGCATATTGAAGACGGGCGTCTGATTCGCGTACTGGAGCCATGGTGTAAGCC
GTTTCCTGGCTACTACTTGTATTATCCCAGTCGTAAACAGCCTTCCCCAGCGTTCTCATTGGTTGTTGAAGCGCTTCGGG
TAGGGTGA

Upstream 100 bases:

>100_bases
AACTCTTGCTGAAAATTTTACATGCAGGGTGCAAAATAACTAGCTAATGAATACTTAATGACTTTATAACCAATGCTTAT
TAATAGGGTGGCTAGACCAG

Downstream 100 bases:

>100_bases
AAATGCAGACCCGCCCAAGTCACTTGGGCAAAAATCTTTGCCGGGCGATGATAATCACCACCCGGCTCGGTTTAGTTAGA
AGGTGACGTTGACCTTGGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKRNLNDLLYFVTVARESSFTRAAAQLGVTQPALSQAISALEERMQIRLLTRTTRSVSPTSAGERLLLAIGNRIDEIEAE
LDMLTELRDKPAGRVRITCGPDVLHSTLLPKLSPLLREYPDINIEFDANHGFRDIVADRFDAGVRLGDTIDKDMIAVPIG
PKLRMAVVAAPDYFSRYPIPNTPHELTQHLCINQRMVRSGGLYVWDFDQDGGDLNVRVSGQLIFNTSVHIVDAALAGLGI
AFLPEEEFGKHIEDGRLIRVLEPWCKPFPGYYLYYPSRKQPSPAFSLVVEALRVG

Sequences:

>Translated_295_residues
MKRNLNDLLYFVTVARESSFTRAAAQLGVTQPALSQAISALEERMQIRLLTRTTRSVSPTSAGERLLLAIGNRIDEIEAE
LDMLTELRDKPAGRVRITCGPDVLHSTLLPKLSPLLREYPDINIEFDANHGFRDIVADRFDAGVRLGDTIDKDMIAVPIG
PKLRMAVVAAPDYFSRYPIPNTPHELTQHLCINQRMVRSGGLYVWDFDQDGGDLNVRVSGQLIFNTSVHIVDAALAGLGI
AFLPEEEFGKHIEDGRLIRVLEPWCKPFPGYYLYYPSRKQPSPAFSLVVEALRVG
>Mature_295_residues
MKRNLNDLLYFVTVARESSFTRAAAQLGVTQPALSQAISALEERMQIRLLTRTTRSVSPTSAGERLLLAIGNRIDEIEAE
LDMLTELRDKPAGRVRITCGPDVLHSTLLPKLSPLLREYPDINIEFDANHGFRDIVADRFDAGVRLGDTIDKDMIAVPIG
PKLRMAVVAAPDYFSRYPIPNTPHELTQHLCINQRMVRSGGLYVWDFDQDGGDLNVRVSGQLIFNTSVHIVDAALAGLGI
AFLPEEEFGKHIEDGRLIRVLEPWCKPFPGYYLYYPSRKQPSPAFSLVVEALRVG

Specific function: May have a role in the regulation of oprD expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=294, Percent_Identity=45.2380952380952, Blast_Score=268, Evalue=4e-73,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=37.9661016949153, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI1786401, Length=280, Percent_Identity=30.7142857142857, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1789440, Length=271, Percent_Identity=28.7822878228782, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=31.5254237288136, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=29.0657439446367, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789639, Length=278, Percent_Identity=28.4172661870504, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786448, Length=286, Percent_Identity=26.2237762237762, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI145693105, Length=162, Percent_Identity=29.0123456790123, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789173, Length=256, Percent_Identity=28.515625, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787879, Length=301, Percent_Identity=27.5747508305648, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI157672245, Length=172, Percent_Identity=29.6511627906977, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788706, Length=262, Percent_Identity=25.9541984732824, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788748, Length=124, Percent_Identity=36.2903225806452, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790011, Length=258, Percent_Identity=22.8682170542636, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788297, Length=129, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1786713, Length=274, Percent_Identity=25.9124087591241, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32942; Mature: 32942

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRNLNDLLYFVTVARESSFTRAAAQLGVTQPALSQAISALEERMQIRLLTRTTRSVSPT
CCCCHHHHEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SAGERLLLAIGNRIDEIEAELDMLTELRDKPAGRVRITCGPDVLHSTLLPKLSPLLREYP
CCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCC
DINIEFDANHGFRDIVADRFDAGVRLGDTIDKDMIAVPIGPKLRMAVVAAPDYFSRYPIP
CCEEEECCCCCHHHHHHHHHHCCCEECCCCCCCEEEECCCCCEEEEEEECCHHHHCCCCC
NTPHELTQHLCINQRMVRSGGLYVWDFDQDGGDLNVRVSGQLIFNTSVHIVDAALAGLGI
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEEEEEECCHHHHHHHHHHCCE
AFLPEEEFGKHIEDGRLIRVLEPWCKPFPGYYLYYPSRKQPSPAFSLVVEALRVG
EECCCHHHCCCCCCCCEEEEECHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKRNLNDLLYFVTVARESSFTRAAAQLGVTQPALSQAISALEERMQIRLLTRTTRSVSPT
CCCCHHHHEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SAGERLLLAIGNRIDEIEAELDMLTELRDKPAGRVRITCGPDVLHSTLLPKLSPLLREYP
CCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCC
DINIEFDANHGFRDIVADRFDAGVRLGDTIDKDMIAVPIGPKLRMAVVAAPDYFSRYPIP
CCEEEECCCCCHHHHHHHHHHCCCEECCCCCCCEEEECCCCCEEEEEEECCHHHHCCCCC
NTPHELTQHLCINQRMVRSGGLYVWDFDQDGGDLNVRVSGQLIFNTSVHIVDAALAGLGI
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEEEEEECCHHHHHHHHHHCCE
AFLPEEEFGKHIEDGRLIRVLEPWCKPFPGYYLYYPSRKQPSPAFSLVVEALRVG
EECCCHHHCCCCCCCCEEEEECHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]