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The map label for this gene is iorA [H]

Identifier: 157370560

GI number: 157370560

Start: 2532621

End: 2533079

Strand: Direct

Name: iorA [H]

Synonym: Spro_2320

Alternate gene names: 157370560

Gene position: 2532621-2533079 (Clockwise)

Preceding gene: 157370559

Following gene: 157370561

Centisome position: 46.48

GC content: 61.22

Gene sequence:

>459_bases
ATGATAACTTTAACCGTGAACGACCAACCGCTGACGTTTGATGGCGACCCGCATATGCCGCTGCTGTGGTTCCTGCGTGA
TGAAGCCGGGCTGACCGGCACCAAATTTGGCTGCGGCATTGCGATGTGCGGCGCTTGTACCGTTCATCTGGACGGCGTGC
CGGTGCGGTCTTGCATGACGCCGGTCTCTGCCGCCGAGGGCAAGAAAATTACCACCATCGAAGCGATCGGCGAGACGCCG
ACGGGCAAAGCGGTGCAGGCGGCCTGGGTCAATCTGGACGTGGTGCAATGCGGCTACTGCCAGTCCGGCCAGATCATGAG
CGCCAGCGCACTGCTGGCCCAAAGCAAGAACCCGAGCGATGCAGATATTGACGCGGCGATGAGTGGCAACGTTTGCCGCT
GCGCTACCTACGTGCGCATTCGCGCCGCCATTCACCAGGCCGCCAAGGCGTTGGATTAA

Upstream 100 bases:

>100_bases
GTCGGGAATGCTCTGGCGCTGCTCGGGCGGCCCCGCAGTTCACTGAGCCTGCCTTTACACCGTCCCAACAGTGACGCCAG
CGTCTGACAAGGAGAACAGC

Downstream 100 bases:

>100_bases
GGGAGAAACCCATGAGCAACGCCCTGAGATGGCTGTTATGGCTGATTGTCGCAATAGTGGTGCTAGCGGGAGGCTACGCG
CTTTATACCCTGTTACGTCC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MITLTVNDQPLTFDGDPHMPLLWFLRDEAGLTGTKFGCGIAMCGACTVHLDGVPVRSCMTPVSAAEGKKITTIEAIGETP
TGKAVQAAWVNLDVVQCGYCQSGQIMSASALLAQSKNPSDADIDAAMSGNVCRCATYVRIRAAIHQAAKALD

Sequences:

>Translated_152_residues
MITLTVNDQPLTFDGDPHMPLLWFLRDEAGLTGTKFGCGIAMCGACTVHLDGVPVRSCMTPVSAAEGKKITTIEAIGETP
TGKAVQAAWVNLDVVQCGYCQSGQIMSASALLAQSKNPSDADIDAAMSGNVCRCATYVRIRAAIHQAAKALD
>Mature_152_residues
MITLTVNDQPLTFDGDPHMPLLWFLRDEAGLTGTKFGCGIAMCGACTVHLDGVPVRSCMTPVSAAEGKKITTIEAIGETP
TGKAVQAAWVNLDVVQCGYCQSGQIMSASALLAQSKNPSDADIDAAMSGNVCRCATYVRIRAAIHQAAKALD

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=147, Percent_Identity=35.3741496598639, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=39.5061728395062, Blast_Score=107, Evalue=4e-25,
Organism=Escherichia coli, GI1789232, Length=143, Percent_Identity=39.8601398601399, Blast_Score=98, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=145, Percent_Identity=38.6206896551724, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=140, Percent_Identity=35.7142857142857, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI32566215, Length=140, Percent_Identity=33.5714285714286, Blast_Score=93, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17737937, Length=149, Percent_Identity=38.255033557047, Blast_Score=96, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24647193, Length=137, Percent_Identity=33.5766423357664, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24647199, Length=138, Percent_Identity=34.0579710144928, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=32.258064516129, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=30.2469135802469, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=30.2469135802469, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 15930; Mature: 15930

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
9.2 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
9.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLTVNDQPLTFDGDPHMPLLWFLRDEAGLTGTKFGCGIAMCGACTVHLDGVPVRSCMT
CEEEEECCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCEEEECEEEEEECCCCHHHHCC
PVSAAEGKKITTIEAIGETPTGKAVQAAWVNLDVVQCGYCQSGQIMSASALLAQSKNPSD
CCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCCCEEEHHHHHHCCCCCCC
ADIDAAMSGNVCRCATYVRIRAAIHQAAKALD
CCCCHHCCCCEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITLTVNDQPLTFDGDPHMPLLWFLRDEAGLTGTKFGCGIAMCGACTVHLDGVPVRSCMT
CEEEEECCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCEEEECEEEEEECCCCHHHHCC
PVSAAEGKKITTIEAIGETPTGKAVQAAWVNLDVVQCGYCQSGQIMSASALLAQSKNPSD
CCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCCCEEEHHHHHHCCCCCCC
ADIDAAMSGNVCRCATYVRIRAAIHQAAKALD
CCCCHHCCCCEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]