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The map label for this gene is iorB [H]

Identifier: 157370559

GI number: 157370559

Start: 2530400

End: 2532607

Strand: Direct

Name: iorB [H]

Synonym: Spro_2319

Alternate gene names: 157370559

Gene position: 2530400-2532607 (Clockwise)

Preceding gene: 157370557

Following gene: 157370560

Centisome position: 46.44

GC content: 61.28

Gene sequence:

>2208_bases
ATGAATCTACCCGAAGTCCCGCTTACCCGGCGGCGTTTTATCGTCGGCGCCAGTGCTCTGGTGATCGGTGCGTATCTGCC
GTCTACCGGTGCGCTGGCCCGAGCCAACTCCGCCACGGCGCCTGAAAACAATCCTCATGCAGCCAATGCCTTCGTGCAGA
TTGATCAGGAAGGCATTGTCACCGTTATCAGTAAACATACCGAGGTGGGCCAGGGGGTGTATACCGGCATGGCGACATTG
GTCGCCGAAGAGCTGGACGCCGATTGGTCGCAGGTGCGGGTGGTTGCCGCGCCGGTTGATACCAACGTCTATAAAAATCT
GTCGTTCGGTTTCCAGGGCACCGGTGGCTCCAGTTCGGTGGCCAATGCCTATGAGCAGATGCGTCGTATGGGGGCCATGG
CGCGTGCAATGCTGGTGCAGGCCGCCGCGCAAAGTTGGAAAACCTCCGCGCAGGAAATTACCGTGCAGGCGGGCAAGATC
CGCCATGCCGCCAGTGGGCGTGAAGCGGGCTTCGGCGAGTTTGCCGTATTGGCCAGCCAGTTACCGCCACCCGACCCCGC
GACTCTGACACTGAAAGATCCCGCCAATTTTACATTGATCGGCAAGGCCAGCGGCCTGCACCGGGTGGATTCGCTGGCCA
AAACCAACGGTTCGGCGCAATTCACTCAGGACATTCATGAGCCGGATATGTTGACCGTGACCATCAAAAAGCCACCGCGT
TTCGGCGGCAAGGTGGCCTCATTTGACGCCAGTCGGGCGCTGGCGGTAGCGGGCGTCGTGGCGGTGAAGCAGACCGATAC
CGGCGTGGCGGTGTACGCCAAAAATACCTGGGCGGCGATCCAGGGGCGTGAAAAATTACAGGTGGAGTGGGACGACTCGC
AGGCCGAGCGGCGCAACACCGAGCAGATTTTCGCCGAGTTCCGCCAGGTGGCGCAAAAGCCCGGTGCGGTGGCGAAAAGT
CACGGCCAGCCGGACGAGGTTTTTGATAAAGCAGACAAAGTGATCGAAGCGGAATACACCTTCCCGTATGTGGCCCATGC
GCCGATGGAGCCGTTGGACGGCTATCTGTTCTGGGACGGCGAAAGCGTCAAGGCGCGTTATGGCTGCCAGATCCAAACCC
TCGATCATCAGCAACTGTGCGATCTGTTCCAATTGCCGCCGGAGAAGGTAGAAATTGAAACCATTTTAGCCGGCGGCAGC
TTTGGTCGCCGTATCGATCTGGGCAACCCGAAGCTGGGGCCGGATCTGGCCGCAGACATGGCGGCGGCCGCCAAGGCGAT
TGGTCCTGGGCACGGGGTGAAGGTGGTGTGGACGCGTGAAGACGATATCCGCAACGGCTGGTATCGCCCGATGATCCTGC
ACCGGCTGCGCGGGGCGATCCGCGGCGGCAAGGTGGTGGGCTGGAGCGATACCGTCGTCGGCCATTCCTGGACGCTCAAC
AGTGCGATGACTGCACTGGTGGTTAACGGTGTCGATCAGATGATGATCGAAGGTGCCAGCGAAGTTCCTTATACCTTCGA
GAGTTTCCGCTGCGACGCCCATATCGTGCCGGGCAAGGTACCCACTACCTCACTGAGGTCGGTGGCCAGTACCCACACCG
GCCACGCGGTGGAAAGCTTTATCGACCAACTGTTGCAGGAAACCGGGCAGGATCCGGTAGAGGGGCGATTGGCACTGATG
GGGGATGCGCCGCGTGAGGCTGGCGTATTACGGGCGGTGGCGAAAGCCGCTAACTGGCAGGGCGCGAAGGTGGTGGATGG
CCGGGCGCGGGGGGTTGGCGTCGCCAAGGCGTTTAATACCCGGGTGGCGCAGATTGCCGAGGTGTCGATCGGCGAAGGCG
GCATTCCACGGGTGCACAAGGTGTGGTGTGCGGTGGACTGCGGCGTCGCGGTCAATCCGGATGTGATCCGCGCGCAGATT
GAAGGCGGCATTGGCTACGGTCTGAGCATCGCACTGTACGGCAACATTACGCTAAAAGACGGGGTGGTTGAGCAGTCCAA
CTTCAACAATTTCCGCCCGCTGCGTATCGATGAAATGCCGGAAATAGAGGTGATTATCGTGCCTTCCAGCGAGGCCCCGA
CCGGCGTGGGTGAACTGGGTGTGCCGACCATTGCCCCGGCGGTCGGGAATGCTCTGGCGCTGCTCGGGCGGCCCCGCAGT
TCACTGAGCCTGCCTTTACACCGTCCCAACAGTGACGCCAGCGTCTGA

Upstream 100 bases:

>100_bases
AACTATTAGCCCGTCGCGCTGGTGTATGCAGACGGCGCGCATAAAAAGAATGATTTCGCCGCATTGATTAAGGTTGATCG
GCATTTTGGAGCGATGAGCA

Downstream 100 bases:

>100_bases
CAAGGAGAACAGCATGATAACTTTAACCGTGAACGACCAACCGCTGACGTTTGATGGCGACCCGCATATGCCGCTGCTGT
GGTTCCTGCGTGATGAAGCC

Product: aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 735; Mature: 735

Protein sequence:

>735_residues
MNLPEVPLTRRRFIVGASALVIGAYLPSTGALARANSATAPENNPHAANAFVQIDQEGIVTVISKHTEVGQGVYTGMATL
VAEELDADWSQVRVVAAPVDTNVYKNLSFGFQGTGGSSSVANAYEQMRRMGAMARAMLVQAAAQSWKTSAQEITVQAGKI
RHAASGREAGFGEFAVLASQLPPPDPATLTLKDPANFTLIGKASGLHRVDSLAKTNGSAQFTQDIHEPDMLTVTIKKPPR
FGGKVASFDASRALAVAGVVAVKQTDTGVAVYAKNTWAAIQGREKLQVEWDDSQAERRNTEQIFAEFRQVAQKPGAVAKS
HGQPDEVFDKADKVIEAEYTFPYVAHAPMEPLDGYLFWDGESVKARYGCQIQTLDHQQLCDLFQLPPEKVEIETILAGGS
FGRRIDLGNPKLGPDLAADMAAAAKAIGPGHGVKVVWTREDDIRNGWYRPMILHRLRGAIRGGKVVGWSDTVVGHSWTLN
SAMTALVVNGVDQMMIEGASEVPYTFESFRCDAHIVPGKVPTTSLRSVASTHTGHAVESFIDQLLQETGQDPVEGRLALM
GDAPREAGVLRAVAKAANWQGAKVVDGRARGVGVAKAFNTRVAQIAEVSIGEGGIPRVHKVWCAVDCGVAVNPDVIRAQI
EGGIGYGLSIALYGNITLKDGVVEQSNFNNFRPLRIDEMPEIEVIIVPSSEAPTGVGELGVPTIAPAVGNALALLGRPRS
SLSLPLHRPNSDASV

Sequences:

>Translated_735_residues
MNLPEVPLTRRRFIVGASALVIGAYLPSTGALARANSATAPENNPHAANAFVQIDQEGIVTVISKHTEVGQGVYTGMATL
VAEELDADWSQVRVVAAPVDTNVYKNLSFGFQGTGGSSSVANAYEQMRRMGAMARAMLVQAAAQSWKTSAQEITVQAGKI
RHAASGREAGFGEFAVLASQLPPPDPATLTLKDPANFTLIGKASGLHRVDSLAKTNGSAQFTQDIHEPDMLTVTIKKPPR
FGGKVASFDASRALAVAGVVAVKQTDTGVAVYAKNTWAAIQGREKLQVEWDDSQAERRNTEQIFAEFRQVAQKPGAVAKS
HGQPDEVFDKADKVIEAEYTFPYVAHAPMEPLDGYLFWDGESVKARYGCQIQTLDHQQLCDLFQLPPEKVEIETILAGGS
FGRRIDLGNPKLGPDLAADMAAAAKAIGPGHGVKVVWTREDDIRNGWYRPMILHRLRGAIRGGKVVGWSDTVVGHSWTLN
SAMTALVVNGVDQMMIEGASEVPYTFESFRCDAHIVPGKVPTTSLRSVASTHTGHAVESFIDQLLQETGQDPVEGRLALM
GDAPREAGVLRAVAKAANWQGAKVVDGRARGVGVAKAFNTRVAQIAEVSIGEGGIPRVHKVWCAVDCGVAVNPDVIRAQI
EGGIGYGLSIALYGNITLKDGVVEQSNFNNFRPLRIDEMPEIEVIIVPSSEAPTGVGELGVPTIAPAVGNALALLGRPRS
SLSLPLHRPNSDASV
>Mature_735_residues
MNLPEVPLTRRRFIVGASALVIGAYLPSTGALARANSATAPENNPHAANAFVQIDQEGIVTVISKHTEVGQGVYTGMATL
VAEELDADWSQVRVVAAPVDTNVYKNLSFGFQGTGGSSSVANAYEQMRRMGAMARAMLVQAAAQSWKTSAQEITVQAGKI
RHAASGREAGFGEFAVLASQLPPPDPATLTLKDPANFTLIGKASGLHRVDSLAKTNGSAQFTQDIHEPDMLTVTIKKPPR
FGGKVASFDASRALAVAGVVAVKQTDTGVAVYAKNTWAAIQGREKLQVEWDDSQAERRNTEQIFAEFRQVAQKPGAVAKS
HGQPDEVFDKADKVIEAEYTFPYVAHAPMEPLDGYLFWDGESVKARYGCQIQTLDHQQLCDLFQLPPEKVEIETILAGGS
FGRRIDLGNPKLGPDLAADMAAAAKAIGPGHGVKVVWTREDDIRNGWYRPMILHRLRGAIRGGKVVGWSDTVVGHSWTLN
SAMTALVVNGVDQMMIEGASEVPYTFESFRCDAHIVPGKVPTTSLRSVASTHTGHAVESFIDQLLQETGQDPVEGRLALM
GDAPREAGVLRAVAKAANWQGAKVVDGRARGVGVAKAFNTRVAQIAEVSIGEGGIPRVHKVWCAVDCGVAVNPDVIRAQI
EGGIGYGLSIALYGNITLKDGVVEQSNFNNFRPLRIDEMPEIEVIIVPSSEAPTGVGELGVPTIAPAVGNALALLGRPRS
SLSLPLHRPNSDASV

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 78385; Mature: 78385

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPEVPLTRRRFIVGASALVIGAYLPSTGALARANSATAPENNPHAANAFVQIDQEGIV
CCCCCCCCCHHHEEEECHHHEEEEECCCCCCEECCCCCCCCCCCCCCCCEEEEECCCCEE
TVISKHTEVGQGVYTGMATLVAEELDADWSQVRVVAAPVDTNVYKNLSFGFQGTGGSSSV
EEEHHCCHHCCHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCHHHCCCCCCCCCCCCHHH
ANAYEQMRRMGAMARAMLVQAAAQSWKTSAQEITVQAGKIRHAASGREAGFGEFAVLASQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCEEECCCCCCCCCCHHHHHHHC
LPPPDPATLTLKDPANFTLIGKASGLHRVDSLAKTNGSAQFTQDIHEPDMLTVTIKKPPR
CCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHCCCCCEEEEEEECCCC
FGGKVASFDASRALAVAGVVAVKQTDTGVAVYAKNTWAAIQGREKLQVEWDDSQAERRNT
CCCEEECCCCHHHHHHEEEEEEEECCCCEEEEECCCEEEECCCCEEEEEECCCHHHHCCH
EQIFAEFRQVAQKPGAVAKSHGQPDEVFDKADKVIEAEYTFPYVAHAPMEPLDGYLFWDG
HHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHEEEEECCCCEEECCCCCCCCCEEEECC
ESVKARYGCQIQTLDHQQLCDLFQLPPEKVEIETILAGGSFGRRIDLGNPKLGPDLAADM
CCCEEEECEEEEECCHHHHHHHHCCCCCCEEEEEEEECCCCCCEEECCCCCCCCHHHHHH
AAAAKAIGPGHGVKVVWTREDDIRNGWYRPMILHRLRGAIRGGKVVGWSDTVVGHSWTLN
HHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEHH
SAMTALVVNGVDQMMIEGASEVPYTFESFRCDAHIVPGKVPTTSLRSVASTHTGHAVESF
HHHHHHHHHCHHHHHHCCCCCCCEEHHHHCCCEEECCCCCCCHHHHHHHHCCCCHHHHHH
IDQLLQETGQDPVEGRLALMGDAPREAGVLRAVAKAANWQGAKVVDGRARGVGVAKAFNT
HHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCCEEHHHHHHH
RVAQIAEVSIGEGGIPRVHKVWCAVDCGVAVNPDVIRAQIEGGIGYGLSIALYGNITLKD
HHHHHEEEECCCCCCCHHEEEEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEEEEEEEC
GVVEQSNFNNFRPLRIDEMPEIEVIIVPSSEAPTGVGELGVPTIAPAVGNALALLGRPRS
CEEECCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCC
SLSLPLHRPNSDASV
CCCCCEECCCCCCCC
>Mature Secondary Structure
MNLPEVPLTRRRFIVGASALVIGAYLPSTGALARANSATAPENNPHAANAFVQIDQEGIV
CCCCCCCCCHHHEEEECHHHEEEEECCCCCCEECCCCCCCCCCCCCCCCEEEEECCCCEE
TVISKHTEVGQGVYTGMATLVAEELDADWSQVRVVAAPVDTNVYKNLSFGFQGTGGSSSV
EEEHHCCHHCCHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCHHHCCCCCCCCCCCCHHH
ANAYEQMRRMGAMARAMLVQAAAQSWKTSAQEITVQAGKIRHAASGREAGFGEFAVLASQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCCEEECCCCCCCCCCHHHHHHHC
LPPPDPATLTLKDPANFTLIGKASGLHRVDSLAKTNGSAQFTQDIHEPDMLTVTIKKPPR
CCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHCCCCCEEEEEEECCCC
FGGKVASFDASRALAVAGVVAVKQTDTGVAVYAKNTWAAIQGREKLQVEWDDSQAERRNT
CCCEEECCCCHHHHHHEEEEEEEECCCCEEEEECCCEEEECCCCEEEEEECCCHHHHCCH
EQIFAEFRQVAQKPGAVAKSHGQPDEVFDKADKVIEAEYTFPYVAHAPMEPLDGYLFWDG
HHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHEEEEECCCCEEECCCCCCCCCEEEECC
ESVKARYGCQIQTLDHQQLCDLFQLPPEKVEIETILAGGSFGRRIDLGNPKLGPDLAADM
CCCEEEECEEEEECCHHHHHHHHCCCCCCEEEEEEEECCCCCCEEECCCCCCCCHHHHHH
AAAAKAIGPGHGVKVVWTREDDIRNGWYRPMILHRLRGAIRGGKVVGWSDTVVGHSWTLN
HHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCEEHH
SAMTALVVNGVDQMMIEGASEVPYTFESFRCDAHIVPGKVPTTSLRSVASTHTGHAVESF
HHHHHHHHHCHHHHHHCCCCCCCEEHHHHCCCEEECCCCCCCHHHHHHHHCCCCHHHHHH
IDQLLQETGQDPVEGRLALMGDAPREAGVLRAVAKAANWQGAKVVDGRARGVGVAKAFNT
HHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCCEEHHHHHHH
RVAQIAEVSIGEGGIPRVHKVWCAVDCGVAVNPDVIRAQIEGGIGYGLSIALYGNITLKD
HHHHHEEEECCCCCCCHHEEEEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEEEEEEEC
GVVEQSNFNNFRPLRIDEMPEIEVIIVPSSEAPTGVGELGVPTIAPAVGNALALLGRPRS
CEEECCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCC
SLSLPLHRPNSDASV
CCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]