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The map label for this gene is dcp [H]

Identifier: 157370546

GI number: 157370546

Start: 2511495

End: 2513696

Strand: Direct

Name: dcp [H]

Synonym: Spro_2306

Alternate gene names: 157370546

Gene position: 2511495-2513696 (Clockwise)

Preceding gene: 157370542

Following gene: 157370552

Centisome position: 46.09

GC content: 54.59

Gene sequence:

>2202_bases
ATGCGTTTATCGACATTGGTGTTGGCGATCGGCATGGCGCTGGGCACGCAGGCACAGGCAGCAGAAACCAACCCGCACGC
GGATCATAGCGCGTTGCCAAGTGGCCAGGCGAAGGAGGCAACCGTGACCGGTGAAGCCAACCAACACGACAACAAAAAGA
ACCAAAACCCGTTCTTCTATCAAAGCCGTCTGCCATTCCAGGCGCCGCCGTTCAATCTGATCAAAGAAAGTGATTATGCC
CCGGCAATTGATGCGGGCATCAAGCAGAAACTGGAAGAGATTGAGAAGATTGCCAACAACCCGGCCAAGCCTGATTTTAA
AAATACCTTTGTGGCAATGGAACAAAGCGGCGCGTTGCTGTCGCGAGTGATGAACGTCTTTGGCGCCATGACCTCGGCCA
ACACCAGCGACGGGTTGCAAAAACTCGATGAGCAAAGCTCGCCGAAGCTGGCGGCGCTGGATGATGCCATCATGCTCAAC
AGCAAGCTGTTTGCCCGTATCAAGGCCGTTTATCAACAGCGCGATGAGCTAAAACTGGATGCGGAATCGCGTCGGCTGGT
TGAAGTGACCTACAAGAACTTTGAGCTGGCGGGGGCCAATCTGTCCGACGCCGATAAAACCAAACTTAAGGCGCTGAACC
AGGAAGCGGCAACGCTGAGCACCCAGTTCTCCAACAAACTGCTGGCGGCGACCAAAGATGGCGCATTGGCGATCGCTGAC
AAAGGCAATCTGGACGGCCTGTCGGAAAGCGAACTGGCGGCGGCGGCCCAGGCGGCCGGCGAACGCAAGCTGGATAAACA
GTGGCTGCTGGTGTTGCAAAACACCACCCAACAGCCGGAATTGCAAAGCCTGAAAAACCGCGAGACCCGCAAGGCACTGT
TTGATGCTTCGTGGAACCGTGCGGAAAAGGGCGACGCTAACGACACCCGTCAGACCATTGCTCGTCTGGCTAAAGTGCGT
GCCGAGCAGGCCAAACTGCTGGGCTTCCCGAATTACGCGGCCTGGAAGCTGCAAAACCAGATGGCCAAAACCCCGGATGC
GGCGCTGAGTTTTATGCGTAATATCGTTCCGGCGGCCACCGCGCGTGCCGAACGTGAAGCCAAAGATATTCAGGCGGTCA
TCGACCAGCAGAAAGGCAATTTCAAGGTTGAAGCCTGGGATTGGCAGTTTTACGCTGAACAGGTGCGCAAAGCCAAATAT
GACCTGGATGAGTCGCAGATCAAACCTTACTTCGAACTGGATAACGTGCTGAACAACGGCGTGTTCTATGCCGCCAACCT
GCTGTACGGCATCAGTTTCAAAGAGCGCAAGGACATCCCGGTTTATCAGCCGGACGTGCGGGTTTATGAGGTGTTCGATA
AAGACGGTAAATCATTGGCGCTGTTCTATACCGACTTCTTTAAGCGCGACAACAAGGGCGGTGGCGCCTGGATGAGCAAT
TTTGTCGAACAATCGAAGCTGAAAGGCACCAAACCGGTAATTTACAACGTCGCCAACTTCACCAAACCGGCACCGGGCCA
GCCTGCGTTGTTGTCGTACGATGACGTGATCACCATGTTCCACGAATTTGGTCATGCGCTGCACGGCATGTTCGCCGATC
AGGAATATCCAAGCCTGTCCGGCACCAACACGGCCCGTGACTTCGTTGAGTTCCCATCGCAGTTTAACGAGCATTGGGCC
AGCGATCCGAAAGTCTTTGCCCACTTCGCCAAGCATTACAAAACCGGTGAAGCCATGCCGCAGGAACTGGTCGACAAAAT
CAAAAAGGCCGACAAGTTCAACAAAGGCTATGACATGACCGAGCTGCTTTCTGCGGCACTGCTGGACATGCACTGGCATA
TGTTGAGCGCCGACCAGCCGCAGCAGGACGTGGACAAGTTCGAGGCGGAATCGCTGATGAAAGACAAAATCGATCTTAGC
TATGTGCCGCCGCGCTATCGCTCCAGTTACTTCAAGCACATTTGGGGTAACGGCTATGCTGCCGGTTATTACGCCTATCT
GTGGACAGAAATGCTGGCGGATGATGCGTTTCAGTGGTTCACCGAACATGGCGGCCTGACGGCAGAGAACGGCCAGCGTT
TCCGCAATATGATCCTGTCGCGCGGTAACAGCCAGGATCTGGAAAAACTGTACATCGACTGGCGCGGCAAAGAGCCAAGC
ATTGAGCCGATGCTGATTAACCGTGGCCTGAAAGACGAATAA

Upstream 100 bases:

>100_bases
TTTTGCTCAATCTGCCAACTGCGCCTAAGCTAGGATGTGACTCAAGGGGAGATGAGCTCTCCGCGACATTATTCTGTGGA
CATGGAGGAGTTTCGATTTG

Downstream 100 bases:

>100_bases
CAGGTCATGGCATTAGCCTGGTGAGTAGTGATAAGAGGGCGTAAGAAATTACGCCCTCTTTATTTGTTATAAGCAGTTTG
GTTGAGATTAAGGAGTGAAG

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 733; Mature: 733

Protein sequence:

>733_residues
MRLSTLVLAIGMALGTQAQAAETNPHADHSALPSGQAKEATVTGEANQHDNKKNQNPFFYQSRLPFQAPPFNLIKESDYA
PAIDAGIKQKLEEIEKIANNPAKPDFKNTFVAMEQSGALLSRVMNVFGAMTSANTSDGLQKLDEQSSPKLAALDDAIMLN
SKLFARIKAVYQQRDELKLDAESRRLVEVTYKNFELAGANLSDADKTKLKALNQEAATLSTQFSNKLLAATKDGALAIAD
KGNLDGLSESELAAAAQAAGERKLDKQWLLVLQNTTQQPELQSLKNRETRKALFDASWNRAEKGDANDTRQTIARLAKVR
AEQAKLLGFPNYAAWKLQNQMAKTPDAALSFMRNIVPAATARAEREAKDIQAVIDQQKGNFKVEAWDWQFYAEQVRKAKY
DLDESQIKPYFELDNVLNNGVFYAANLLYGISFKERKDIPVYQPDVRVYEVFDKDGKSLALFYTDFFKRDNKGGGAWMSN
FVEQSKLKGTKPVIYNVANFTKPAPGQPALLSYDDVITMFHEFGHALHGMFADQEYPSLSGTNTARDFVEFPSQFNEHWA
SDPKVFAHFAKHYKTGEAMPQELVDKIKKADKFNKGYDMTELLSAALLDMHWHMLSADQPQQDVDKFEAESLMKDKIDLS
YVPPRYRSSYFKHIWGNGYAAGYYAYLWTEMLADDAFQWFTEHGGLTAENGQRFRNMILSRGNSQDLEKLYIDWRGKEPS
IEPMLINRGLKDE

Sequences:

>Translated_733_residues
MRLSTLVLAIGMALGTQAQAAETNPHADHSALPSGQAKEATVTGEANQHDNKKNQNPFFYQSRLPFQAPPFNLIKESDYA
PAIDAGIKQKLEEIEKIANNPAKPDFKNTFVAMEQSGALLSRVMNVFGAMTSANTSDGLQKLDEQSSPKLAALDDAIMLN
SKLFARIKAVYQQRDELKLDAESRRLVEVTYKNFELAGANLSDADKTKLKALNQEAATLSTQFSNKLLAATKDGALAIAD
KGNLDGLSESELAAAAQAAGERKLDKQWLLVLQNTTQQPELQSLKNRETRKALFDASWNRAEKGDANDTRQTIARLAKVR
AEQAKLLGFPNYAAWKLQNQMAKTPDAALSFMRNIVPAATARAEREAKDIQAVIDQQKGNFKVEAWDWQFYAEQVRKAKY
DLDESQIKPYFELDNVLNNGVFYAANLLYGISFKERKDIPVYQPDVRVYEVFDKDGKSLALFYTDFFKRDNKGGGAWMSN
FVEQSKLKGTKPVIYNVANFTKPAPGQPALLSYDDVITMFHEFGHALHGMFADQEYPSLSGTNTARDFVEFPSQFNEHWA
SDPKVFAHFAKHYKTGEAMPQELVDKIKKADKFNKGYDMTELLSAALLDMHWHMLSADQPQQDVDKFEAESLMKDKIDLS
YVPPRYRSSYFKHIWGNGYAAGYYAYLWTEMLADDAFQWFTEHGGLTAENGQRFRNMILSRGNSQDLEKLYIDWRGKEPS
IEPMLINRGLKDE
>Mature_733_residues
MRLSTLVLAIGMALGTQAQAAETNPHADHSALPSGQAKEATVTGEANQHDNKKNQNPFFYQSRLPFQAPPFNLIKESDYA
PAIDAGIKQKLEEIEKIANNPAKPDFKNTFVAMEQSGALLSRVMNVFGAMTSANTSDGLQKLDEQSSPKLAALDDAIMLN
SKLFARIKAVYQQRDELKLDAESRRLVEVTYKNFELAGANLSDADKTKLKALNQEAATLSTQFSNKLLAATKDGALAIAD
KGNLDGLSESELAAAAQAAGERKLDKQWLLVLQNTTQQPELQSLKNRETRKALFDASWNRAEKGDANDTRQTIARLAKVR
AEQAKLLGFPNYAAWKLQNQMAKTPDAALSFMRNIVPAATARAEREAKDIQAVIDQQKGNFKVEAWDWQFYAEQVRKAKY
DLDESQIKPYFELDNVLNNGVFYAANLLYGISFKERKDIPVYQPDVRVYEVFDKDGKSLALFYTDFFKRDNKGGGAWMSN
FVEQSKLKGTKPVIYNVANFTKPAPGQPALLSYDDVITMFHEFGHALHGMFADQEYPSLSGTNTARDFVEFPSQFNEHWA
SDPKVFAHFAKHYKTGEAMPQELVDKIKKADKFNKGYDMTELLSAALLDMHWHMLSADQPQQDVDKFEAESLMKDKIDLS
YVPPRYRSSYFKHIWGNGYAAGYYAYLWTEMLADDAFQWFTEHGGLTAENGQRFRNMILSRGNSQDLEKLYIDWRGKEPS
IEPMLINRGLKDE

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=668, Percent_Identity=25.2994011976048, Blast_Score=227, Evalue=4e-59,
Organism=Homo sapiens, GI14149738, Length=602, Percent_Identity=27.2425249169435, Blast_Score=202, Evalue=9e-52,
Organism=Homo sapiens, GI156105687, Length=745, Percent_Identity=22.9530201342282, Blast_Score=164, Evalue=4e-40,
Organism=Escherichia coli, GI1787819, Length=675, Percent_Identity=63.5555555555556, Blast_Score=877, Evalue=0.0,
Organism=Escherichia coli, GI1789913, Length=676, Percent_Identity=32.6923076923077, Blast_Score=367, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI32565901, Length=584, Percent_Identity=21.5753424657534, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71999758, Length=604, Percent_Identity=20.5298013245033, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319793, Length=702, Percent_Identity=24.9287749287749, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322715, Length=736, Percent_Identity=21.6032608695652, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI21356111, Length=551, Percent_Identity=25.2268602540835, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI20129717, Length=415, Percent_Identity=26.0240963855422, Blast_Score=143, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 82545; Mature: 82545

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSTLVLAIGMALGTQAQAAETNPHADHSALPSGQAKEATVTGEANQHDNKKNQNPFFY
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEE
QSRLPFQAPPFNLIKESDYAPAIDAGIKQKLEEIEKIANNPAKPDFKNTFVAMEQSGALL
ECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEEHHCCHHH
SRVMNVFGAMTSANTSDGLQKLDEQSSPKLAALDDAIMLNSKLFARIKAVYQQRDELKLD
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AESRRLVEVTYKNFELAGANLSDADKTKLKALNQEAATLSTQFSNKLLAATKDGALAIAD
CCCCEEEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEC
KGNLDGLSESELAAAAQAAGERKLDKQWLLVLQNTTQQPELQSLKNRETRKALFDASWNR
CCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
AEKGDANDTRQTIARLAKVRAEQAKLLGFPNYAAWKLQNQMAKTPDAALSFMRNIVPAAT
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ARAEREAKDIQAVIDQQKGNFKVEAWDWQFYAEQVRKAKYDLDESQIKPYFELDNVLNNG
HHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCC
VFYAANLLYGISFKERKDIPVYQPDVRVYEVFDKDGKSLALFYTDFFKRDNKGGGAWMSN
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEHHHHHCCCCCCHHHHHH
FVEQSKLKGTKPVIYNVANFTKPAPGQPALLSYDDVITMFHEFGHALHGMFADQEYPSLS
HHHHHHCCCCCCEEEEHHHCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GTNTARDFVEFPSQFNEHWASDPKVFAHFAKHYKTGEAMPQELVDKIKKADKFNKGYDMT
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHH
ELLSAALLDMHWHMLSADQPQQDVDKFEAESLMKDKIDLSYVPPRYRSSYFKHIWGNGYA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCH
AGYYAYLWTEMLADDAFQWFTEHGGLTAENGQRFRNMILSRGNSQDLEKLYIDWRGKEPS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHEEEECCCCCC
IEPMLINRGLKDE
CCHHHCCCCCCCC
>Mature Secondary Structure
MRLSTLVLAIGMALGTQAQAAETNPHADHSALPSGQAKEATVTGEANQHDNKKNQNPFFY
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEE
QSRLPFQAPPFNLIKESDYAPAIDAGIKQKLEEIEKIANNPAKPDFKNTFVAMEQSGALL
ECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEEHHCCHHH
SRVMNVFGAMTSANTSDGLQKLDEQSSPKLAALDDAIMLNSKLFARIKAVYQQRDELKLD
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AESRRLVEVTYKNFELAGANLSDADKTKLKALNQEAATLSTQFSNKLLAATKDGALAIAD
CCCCEEEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEC
KGNLDGLSESELAAAAQAAGERKLDKQWLLVLQNTTQQPELQSLKNRETRKALFDASWNR
CCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
AEKGDANDTRQTIARLAKVRAEQAKLLGFPNYAAWKLQNQMAKTPDAALSFMRNIVPAAT
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ARAEREAKDIQAVIDQQKGNFKVEAWDWQFYAEQVRKAKYDLDESQIKPYFELDNVLNNG
HHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHCC
VFYAANLLYGISFKERKDIPVYQPDVRVYEVFDKDGKSLALFYTDFFKRDNKGGGAWMSN
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEHHHHHCCCCCCHHHHHH
FVEQSKLKGTKPVIYNVANFTKPAPGQPALLSYDDVITMFHEFGHALHGMFADQEYPSLS
HHHHHHCCCCCCEEEEHHHCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GTNTARDFVEFPSQFNEHWASDPKVFAHFAKHYKTGEAMPQELVDKIKKADKFNKGYDMT
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHH
ELLSAALLDMHWHMLSADQPQQDVDKFEAESLMKDKIDLSYVPPRYRSSYFKHIWGNGYA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCH
AGYYAYLWTEMLADDAFQWFTEHGGLTAENGQRFRNMILSRGNSQDLEKLYIDWRGKEPS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHEEEECCCCCC
IEPMLINRGLKDE
CCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]