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The map label for this gene is intQ [H]

Identifier: 157370504

GI number: 157370504

Start: 2464528

End: 2465814

Strand: Reverse

Name: intQ [H]

Synonym: Spro_2264

Alternate gene names: 157370504

Gene position: 2465814-2464528 (Counterclockwise)

Preceding gene: 157370505

Following gene: 157370503

Centisome position: 45.25

GC content: 46.08

Gene sequence:

>1287_bases
ATGAAGGCTTATCCAACGGGGGTGGAAAATCATGGAGGAACGCTCCGGATCTGGTTCCTCTTCCAGGGGAAGAGAGTCCG
GGAAAACCTTGGTATACCAGACACGCCAAAAAACAGGAAAGCTGCTGGAGAATTGCGAACCTCTGTTTGTTATGAAATAA
AAACTGGCAACTTTTCATACGAAAAGAGGTTCCCAAACTCACGCAACGTTACAATCAACGCAGCGCGTGAAAACATAACG
GTAAATGACATCATTAAAAAATGGTTAAATCTGAAGGAAATGGAGGTATCCAAAGGCACATTGTATAGATATACATCACA
TTGCGGGGTTACCGCGTCATACCTAAATCCAGAAAGAAAAATTAATGAAATCAGGCAAGAGGACATTCTACTCGCCAGAA
AGAGAATGCTTACTGAACCTCAACAACCGAAGATACACGAAAAGCGAAAATCCGTGCGTCAGGGAAGAGCGGTTCCAACT
GTTAACTCTTACATGTTTTGCATGAGGGCAATTTTTGATTTTGCAGTCTCTAATGGGTATATCGCTAACAACCCATTTGA
AGGGGTGTCACCACTCAAAAAACAGCGCCCCGCTCCGGACCCACTCACTAAGGAAGAGTACCAGCGCGTCATTGTCAGCT
GCCCTACCCAGCAGATGAGAAACATGATAACGCTGGCCATTAATACCGGTCTACGCCATGGGGAGCTTTATGCTTTAGCA
TGGGAAGACTTGGACACTCAGAATTGGACAATCAGTATTAGCAGAAACCTCTCTCTAAAAGAGCATTTTACTCTGCCAAA
AACTGATGCTGGCATGAGGACGATCCAGCTTACAACTGTCGCCATAGAGGCCATCAAGTCTCAAATGGCACTGACAAGGT
TGTCGAATGCTCACCGCGTGACAGTAAACCTGCGAGAGTATGGGAAAAAGAGGACAGATGACTGCACGTTCATTTTTTCC
CCCCGGATAACATCCAGGAACGGTTCTAGCGCGGATTGGTACAGTCCGGGCGCGTTCAATGGTGCTTGGAAAACCATTTT
GCGCAAGGCCGGTGTAAAGCACAGGAAATCTTACGAGACGAGACACACGTTTGCCTGCTGGGCGTTATCGTGTGGCGCTA
ACCCAAATTTCGTTGCACACCAGATGGGGCATTCATCAGCACAAATGCTCTACAATGTCTATGGAAAATGGATGACAGAG
AATAACGACCACCAGGTGAACATTTTAAATGCCAGTTTTTCACAGAATGCCCCACAGGTGCCCCATGAGCAAATCATAAA
CATCTAA

Upstream 100 bases:

>100_bases
TCGACATCTGGGTAACCAAGCAGCGCCCAGCCGTTAAGCGTCGCATTTCGCCAAAATTCTGTTTAAATGACATCCCAGTT
CAATAGCAAGAGGAGGTTTC

Downstream 100 bases:

>100_bases
CCAACTGATTTTACACCAACAAAACACACCAACTACGCTTTACCTGGATGAGCAAGATCGGCTCCTTTGCCTTTAGCTTC
CTGCCGGTGATGTTCGCCAT

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MKAYPTGVENHGGTLRIWFLFQGKRVRENLGIPDTPKNRKAAGELRTSVCYEIKTGNFSYEKRFPNSRNVTINAARENIT
VNDIIKKWLNLKEMEVSKGTLYRYTSHCGVTASYLNPERKINEIRQEDILLARKRMLTEPQQPKIHEKRKSVRQGRAVPT
VNSYMFCMRAIFDFAVSNGYIANNPFEGVSPLKKQRPAPDPLTKEEYQRVIVSCPTQQMRNMITLAINTGLRHGELYALA
WEDLDTQNWTISISRNLSLKEHFTLPKTDAGMRTIQLTTVAIEAIKSQMALTRLSNAHRVTVNLREYGKKRTDDCTFIFS
PRITSRNGSSADWYSPGAFNGAWKTILRKAGVKHRKSYETRHTFACWALSCGANPNFVAHQMGHSSAQMLYNVYGKWMTE
NNDHQVNILNASFSQNAPQVPHEQIINI

Sequences:

>Translated_428_residues
MKAYPTGVENHGGTLRIWFLFQGKRVRENLGIPDTPKNRKAAGELRTSVCYEIKTGNFSYEKRFPNSRNVTINAARENIT
VNDIIKKWLNLKEMEVSKGTLYRYTSHCGVTASYLNPERKINEIRQEDILLARKRMLTEPQQPKIHEKRKSVRQGRAVPT
VNSYMFCMRAIFDFAVSNGYIANNPFEGVSPLKKQRPAPDPLTKEEYQRVIVSCPTQQMRNMITLAINTGLRHGELYALA
WEDLDTQNWTISISRNLSLKEHFTLPKTDAGMRTIQLTTVAIEAIKSQMALTRLSNAHRVTVNLREYGKKRTDDCTFIFS
PRITSRNGSSADWYSPGAFNGAWKTILRKAGVKHRKSYETRHTFACWALSCGANPNFVAHQMGHSSAQMLYNVYGKWMTE
NNDHQVNILNASFSQNAPQVPHEQIINI
>Mature_428_residues
MKAYPTGVENHGGTLRIWFLFQGKRVRENLGIPDTPKNRKAAGELRTSVCYEIKTGNFSYEKRFPNSRNVTINAARENIT
VNDIIKKWLNLKEMEVSKGTLYRYTSHCGVTASYLNPERKINEIRQEDILLARKRMLTEPQQPKIHEKRKSVRQGRAVPT
VNSYMFCMRAIFDFAVSNGYIANNPFEGVSPLKKQRPAPDPLTKEEYQRVIVSCPTQQMRNMITLAINTGLRHGELYALA
WEDLDTQNWTISISRNLSLKEHFTLPKTDAGMRTIQLTTVAIEAIKSQMALTRLSNAHRVTVNLREYGKKRTDDCTFIFS
PRITSRNGSSADWYSPGAFNGAWKTILRKAGVKHRKSYETRHTFACWALSCGANPNFVAHQMGHSSAQMLYNVYGKWMTE
NNDHQVNILNASFSQNAPQVPHEQIINI

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1787607, Length=416, Percent_Identity=39.1826923076923, Blast_Score=308, Evalue=3e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR022000
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF12167 DUF3596; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 48920; Mature: 48920

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAYPTGVENHGGTLRIWFLFQGKRVRENLGIPDTPKNRKAAGELRTSVCYEIKTGNFSY
CCCCCCCCCCCCCEEEEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHEEEEEEECCCEEH
EKRFPNSRNVTINAARENITVNDIIKKWLNLKEMEVSKGTLYRYTSHCGVTASYLNPERK
HHCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEECCCCEEEEEECCCCCEEHHCCHHHH
INEIRQEDILLARKRMLTEPQQPKIHEKRKSVRQGRAVPTVNSYMFCMRAIFDFAVSNGY
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCE
IANNPFEGVSPLKKQRPAPDPLTKEEYQRVIVSCPTQQMRNMITLAINTGLRHGELYALA
ECCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCHHHHHCEEEEEEECCCCCCEEEEEE
WEDLDTQNWTISISRNLSLKEHFTLPKTDAGMRTIQLTTVAIEAIKSQMALTRLSNAHRV
ECCCCCCCEEEEEECCCCHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEE
TVNLREYGKKRTDDCTFIFSPRITSRNGSSADWYSPGAFNGAWKTILRKAGVKHRKSYET
EEEHHHCCCCCCCCEEEEECCCEECCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCC
RHTFACWALSCGANPNFVAHQMGHSSAQMLYNVYGKWMTENNDHQVNILNASFSQNAPQV
CCEEEEEEEECCCCCCEEHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
PHEQIINI
CHHHHCCC
>Mature Secondary Structure
MKAYPTGVENHGGTLRIWFLFQGKRVRENLGIPDTPKNRKAAGELRTSVCYEIKTGNFSY
CCCCCCCCCCCCCEEEEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHEEEEEEECCCEEH
EKRFPNSRNVTINAARENITVNDIIKKWLNLKEMEVSKGTLYRYTSHCGVTASYLNPERK
HHCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEECCCCEEEEEECCCCCEEHHCCHHHH
INEIRQEDILLARKRMLTEPQQPKIHEKRKSVRQGRAVPTVNSYMFCMRAIFDFAVSNGY
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCE
IANNPFEGVSPLKKQRPAPDPLTKEEYQRVIVSCPTQQMRNMITLAINTGLRHGELYALA
ECCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCHHHHHCEEEEEEECCCCCCEEEEEE
WEDLDTQNWTISISRNLSLKEHFTLPKTDAGMRTIQLTTVAIEAIKSQMALTRLSNAHRV
ECCCCCCCEEEEEECCCCHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEE
TVNLREYGKKRTDDCTFIFSPRITSRNGSSADWYSPGAFNGAWKTILRKAGVKHRKSYET
EEEHHHCCCCCCCCEEEEECCCEECCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCC
RHTFACWALSCGANPNFVAHQMGHSSAQMLYNVYGKWMTENNDHQVNILNASFSQNAPQV
CCEEEEEEEECCCCCCEEHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
PHEQIINI
CHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]