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The map label for this gene is agaR [H]

Identifier: 157370499

GI number: 157370499

Start: 2460027

End: 2460782

Strand: Reverse

Name: agaR [H]

Synonym: Spro_2259

Alternate gene names: 157370499

Gene position: 2460782-2460027 (Counterclockwise)

Preceding gene: 157370502

Following gene: 157370498

Centisome position: 45.16

GC content: 60.85

Gene sequence:

>756_bases
ATGCTCACCAGCCAACGTAAAAAAATCATTCTGGAAAAACTGGCCGAGGACGGACAGGTTGTGGCCAAACAGCTCAGTGA
GATGTTCGGGTTATCCGAGGATACTCTGCGGCGTGACTTGCGTGAGCTGGACAGCGAAGGACTGTTGCAACGGGTACACG
GCGGTGCGCTGCCGGTCTCCCCGGCGATTGCCACCTTTGCCGAGAGAAACGGGCAGGAATCCACCGCCAAGCGGGCGATT
GCCAAAGCCGCGGCGGCCATGATCGCCCCCGGCCAGGTGGTGATTATTGATGGCGGTACCACCTCCGCCGAGTTGGTGAA
ACACCTGCCACCCACGCTGGAAGCCACCATCGTCACCCACAGCCCCAGCGTGGCGGTCGGCCTGGTTGATCACCCCAAAG
TTGAGGTGATCCTGATTGGCGGGCGGTTGTACAAACATTCGATTGTCAGCGTGGGCGCGGCGGCGGTTGAGGCGATGTCG
CACATTCGCGCCGATCTCTACTTTATGGGCGTGACCGGCGTACACCCGACCGCCGGCCTGAGCACCGGCGATCTCGAAGA
GGCCTATATCAAACGCGCTCTGGCAGCGCGCGCAGCCGAAACCGTAGTGTTGGCCTCTGCCGCCAAGCTGAATGCCGCCT
CGCAGTATGCGATTGGCGATCTCAGTCTGGCACAGAGCATTATTGTCGAACGTTCGACCGACGCCACGCTGATTGCCCCG
CTGGAACAGGCCGGGTTGACGGTAATCAAAGCCTGA

Upstream 100 bases:

>100_bases
GTTGATCAACTCCAGGGTCAGGAAAGGAAATTGATACTATCGTGCAGTTTCGTGTATGATCAAGGTATTTCGTGCAGTGG
AAATTTAACGGGAAAACACC

Downstream 100 bases:

>100_bases
GTGACCTGCGCAATTAAATGACCTAATAAATACGTGGCTATTAAAACTTCCGCGTATTTATTATGGTTAATCTCCGCGCA
TCGGATAAAAATGCGAGAAC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLTSQRKKIILEKLAEDGQVVAKQLSEMFGLSEDTLRRDLRELDSEGLLQRVHGGALPVSPAIATFAERNGQESTAKRAI
AKAAAAMIAPGQVVIIDGGTTSAELVKHLPPTLEATIVTHSPSVAVGLVDHPKVEVILIGGRLYKHSIVSVGAAAVEAMS
HIRADLYFMGVTGVHPTAGLSTGDLEEAYIKRALAARAAETVVLASAAKLNAASQYAIGDLSLAQSIIVERSTDATLIAP
LEQAGLTVIKA

Sequences:

>Translated_251_residues
MLTSQRKKIILEKLAEDGQVVAKQLSEMFGLSEDTLRRDLRELDSEGLLQRVHGGALPVSPAIATFAERNGQESTAKRAI
AKAAAAMIAPGQVVIIDGGTTSAELVKHLPPTLEATIVTHSPSVAVGLVDHPKVEVILIGGRLYKHSIVSVGAAAVEAMS
HIRADLYFMGVTGVHPTAGLSTGDLEEAYIKRALAARAAETVVLASAAKLNAASQYAIGDLSLAQSIIVERSTDATLIAP
LEQAGLTVIKA
>Mature_251_residues
MLTSQRKKIILEKLAEDGQVVAKQLSEMFGLSEDTLRRDLRELDSEGLLQRVHGGALPVSPAIATFAERNGQESTAKRAI
AKAAAAMIAPGQVVIIDGGTTSAELVKHLPPTLEATIVTHSPSVAVGLVDHPKVEVILIGGRLYKHSIVSVGAAAVEAMS
HIRADLYFMGVTGVHPTAGLSTGDLEEAYIKRALAARAAETVVLASAAKLNAASQYAIGDLSLAQSIIVERSTDATLIAP
LEQAGLTVIKA

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=251, Percent_Identity=31.8725099601594, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787540, Length=247, Percent_Identity=30.3643724696356, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI87082344, Length=245, Percent_Identity=28.9795918367347, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789829, Length=231, Percent_Identity=29.004329004329, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788069, Length=253, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI226510968, Length=235, Percent_Identity=30.2127659574468, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789059, Length=252, Percent_Identity=28.1746031746032, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789170, Length=243, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790635, Length=257, Percent_Identity=26.4591439688716, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790753, Length=251, Percent_Identity=26.6932270916335, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787063, Length=226, Percent_Identity=25.2212389380531, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26241; Mature: 26241

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSQRKKIILEKLAEDGQVVAKQLSEMFGLSEDTLRRDLRELDSEGLLQRVHGGALPVS
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCC
PAIATFAERNGQESTAKRAIAKAAAAMIAPGQVVIIDGGTTSAELVKHLPPTLEATIVTH
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCEEEEEEC
SPSVAVGLVDHPKVEVILIGGRLYKHSIVSVGAAAVEAMSHIRADLYFMGVTGVHPTAGL
CCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCC
STGDLEEAYIKRALAARAAETVVLASAAKLNAASQYAIGDLSLAQSIIVERSTDATLIAP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEC
LEQAGLTVIKA
HHHCCEEEECC
>Mature Secondary Structure
MLTSQRKKIILEKLAEDGQVVAKQLSEMFGLSEDTLRRDLRELDSEGLLQRVHGGALPVS
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCC
PAIATFAERNGQESTAKRAIAKAAAAMIAPGQVVIIDGGTTSAELVKHLPPTLEATIVTH
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCEEEEEEC
SPSVAVGLVDHPKVEVILIGGRLYKHSIVSVGAAAVEAMSHIRADLYFMGVTGVHPTAGL
CCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCC
STGDLEEAYIKRALAARAAETVVLASAAKLNAASQYAIGDLSLAQSIIVERSTDATLIAP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEC
LEQAGLTVIKA
HHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]