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The map label for this gene is araC [H]

Identifier: 157370488

GI number: 157370488

Start: 2450337

End: 2451254

Strand: Direct

Name: araC [H]

Synonym: Spro_2248

Alternate gene names: 157370488

Gene position: 2450337-2451254 (Clockwise)

Preceding gene: 157370487

Following gene: 157370489

Centisome position: 44.97

GC content: 58.39

Gene sequence:

>918_bases
ATGTATCATCGCATGGCACAGGAACCGCAACCTAACCCGCTGTTGCCGGGTTACACCTTTAACGCTTATCTGGTGGCGGG
GCTGACGCCGATTATGGCGGACGGTCCGCTGGATTTCTTTATCGACCGCCCCGGCGGCATGAAGGGCTATATTCTCAACC
TGACCATCAAGGGCCAGGGCAAGGTGTTTGACGGTGAAGATACCCTTTACTGCAATCCTGGCGATCTGCTGCTGTTTCCG
CCCAAAGCGGCGCATTACTACGGCCGTTCGCCGGACAGCGACTGCTGGTATCACCGCTGGGTGTATTTCCGTCCGCGCGC
CTACTGGGCCGACTGGCTGGAATGGCACAGCAAAACCCATGAAGTGGGGCGGCTGACCTTGCCGAACAATAACCTGTTAC
TGGAGTTCGATCGGCTGTTCGCCAATATCGAACAGACTCAGCGTTCCGGTCGCCGCTTTGCCGAAGAGCTGGGGATGAAC
CTGCTGGAGCGTCTGCTGTTGCGCGCGATGGAGGAAGACCCGCTCAGCCCACAGAAAATTATGGATCCGCGAGTCATTGA
GGCCTGCCAGTTTATCACCGGCAACCTGGCCGGCGAGCTGCGGATTGACGAGGTGGCGCGCCATGTCTGTTTGTCACCAT
CGCGGTTGGCGCATTTGTTCCGCGAGCAGGTGGGCATCAATATTCTGCGCTGGCGCGAAGATCAGCGGGTGATCCGCGCC
AAGCTGCTGTTGCAGACTACGCAGGAGTCGATCGCCACCATAGGTCGGGTGGTGGGTTATGACGATCAGCTGTACTTTTC
CCGGGTATTTCGCAAGCGGGTGGGCGTTAGCCCGAGCGATTTCCGCCGCCGCAGCCTGGAGATAAACTACCCGGCCAGAA
ATCAACGTGAACAGCCTTATGTGGCGGCCTCAAGTTAA

Upstream 100 bases:

>100_bases
TGCCAACCCTGTTCACAGTTCTGTTATCGGCCCGGGCAGTTATCCACCGGGCCGCTAAGCTAGGATTGATATCTAAGCTA
TAAGATTGCCGGGAGGACCG

Downstream 100 bases:

>100_bases
CATTAAATTTACTTCTTGTTCCCGCCTGCATCATGGTGTCAAATCTGATGGGTCTATTGCGAGCCAGTAAGAGGAAACAC
CATGGCAGAAAAACTTCGGG

Product: DNA-binding transcriptional regulator AraC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MYHRMAQEPQPNPLLPGYTFNAYLVAGLTPIMADGPLDFFIDRPGGMKGYILNLTIKGQGKVFDGEDTLYCNPGDLLLFP
PKAAHYYGRSPDSDCWYHRWVYFRPRAYWADWLEWHSKTHEVGRLTLPNNNLLLEFDRLFANIEQTQRSGRRFAEELGMN
LLERLLLRAMEEDPLSPQKIMDPRVIEACQFITGNLAGELRIDEVARHVCLSPSRLAHLFREQVGINILRWREDQRVIRA
KLLLQTTQESIATIGRVVGYDDQLYFSRVFRKRVGVSPSDFRRRSLEINYPARNQREQPYVAASS

Sequences:

>Translated_305_residues
MYHRMAQEPQPNPLLPGYTFNAYLVAGLTPIMADGPLDFFIDRPGGMKGYILNLTIKGQGKVFDGEDTLYCNPGDLLLFP
PKAAHYYGRSPDSDCWYHRWVYFRPRAYWADWLEWHSKTHEVGRLTLPNNNLLLEFDRLFANIEQTQRSGRRFAEELGMN
LLERLLLRAMEEDPLSPQKIMDPRVIEACQFITGNLAGELRIDEVARHVCLSPSRLAHLFREQVGINILRWREDQRVIRA
KLLLQTTQESIATIGRVVGYDDQLYFSRVFRKRVGVSPSDFRRRSLEINYPARNQREQPYVAASS
>Mature_305_residues
MYHRMAQEPQPNPLLPGYTFNAYLVAGLTPIMADGPLDFFIDRPGGMKGYILNLTIKGQGKVFDGEDTLYCNPGDLLLFP
PKAAHYYGRSPDSDCWYHRWVYFRPRAYWADWLEWHSKTHEVGRLTLPNNNLLLEFDRLFANIEQTQRSGRRFAEELGMN
LLERLLLRAMEEDPLSPQKIMDPRVIEACQFITGNLAGELRIDEVARHVCLSPSRLAHLFREQVGINILRWREDQRVIRA
KLLLQTTQESIATIGRVVGYDDQLYFSRVFRKRVGVSPSDFRRRSLEINYPARNQREQPYVAASS

Specific function: This protein controls the expression of at least six genes that are involved in the transport and catabolism of L- arabinose. It regulates initiation of transcription of the araBAD operon and it also controls its own synthesis. The L-arabinose operon disp

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786251, Length=276, Percent_Identity=59.0579710144928, Blast_Score=319, Evalue=1e-88,
Organism=Escherichia coli, GI1789993, Length=130, Percent_Identity=30, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35420; Mature: 35420

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYHRMAQEPQPNPLLPGYTFNAYLVAGLTPIMADGPLDFFIDRPGGMKGYILNLTIKGQG
CCCCCCCCCCCCCCCCCCCCHHHHEECCCHHHCCCCCEEEEECCCCCCEEEEEEEECCCC
KVFDGEDTLYCNPGDLLLFPPKAAHYYGRSPDSDCWYHRWVYFRPRAYWADWLEWHSKTH
EEECCCCEEEECCCCEEEECCCHHHCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCC
EVGRLTLPNNNLLLEFDRLFANIEQTQRSGRRFAEELGMNLLERLLLRAMEEDPLSPQKI
CCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MDPRVIEACQFITGNLAGELRIDEVARHVCLSPSRLAHLFREQVGINILRWREDQRVIRA
CCHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECHHHHHHHH
KLLLQTTQESIATIGRVVGYDDQLYFSRVFRKRVGVSPSDFRRRSLEINYPARNQREQPY
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCEEEECCCCCCCCCCCE
VAASS
EECCC
>Mature Secondary Structure
MYHRMAQEPQPNPLLPGYTFNAYLVAGLTPIMADGPLDFFIDRPGGMKGYILNLTIKGQG
CCCCCCCCCCCCCCCCCCCCHHHHEECCCHHHCCCCCEEEEECCCCCCEEEEEEEECCCC
KVFDGEDTLYCNPGDLLLFPPKAAHYYGRSPDSDCWYHRWVYFRPRAYWADWLEWHSKTH
EEECCCCEEEECCCCEEEECCCHHHCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCC
EVGRLTLPNNNLLLEFDRLFANIEQTQRSGRRFAEELGMNLLERLLLRAMEEDPLSPQKI
CCCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
MDPRVIEACQFITGNLAGELRIDEVARHVCLSPSRLAHLFREQVGINILRWREDQRVIRA
CCHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECHHHHHHHH
KLLLQTTQESIATIGRVVGYDDQLYFSRVFRKRVGVSPSDFRRRSLEINYPARNQREQPY
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCEEEECCCCCCCCCCCE
VAASS
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3902795 [H]