Click here to switch to the map view.

The map label for this gene is ydhC [H]

Identifier: 157370433

GI number: 157370433

Start: 2394966

End: 2396174

Strand: Reverse

Name: ydhC [H]

Synonym: Spro_2193

Alternate gene names: 157370433

Gene position: 2396174-2394966 (Counterclockwise)

Preceding gene: 157370435

Following gene: 157370432

Centisome position: 43.98

GC content: 56.82

Gene sequence:

>1209_bases
ATGCGAAATTCCTTTGGTTTTATGTTCTATCTTGCCGGCCTGAGTATGCTGGGTTACCTGGCCACCGACATGTACCTGCC
CGCCTTTGGCATAATGCAGCAAGACCTGCAAATTTCCGCCGGGGCGATCAGCGCCAGCCTGAGTATTTTCCTGGCCGGCT
TCGCCTTTGCTCAATTGCTCTGGGGGCCACTTTCCGACCGCCTCGGCCGTAAACCGGTGTTGCTGATTGGCCTGGCGCTG
TTTGCCCTGGGTTGCATGGGCATGCTGTGGGTACAAAATGCCGTTCAACTGTGGTCACTGCGTTTCATCCAGGCCATTGG
CGTCTGTTCCGCCGCCGTCACCTGGCAGGCACTGGTGATTGACCGCTACCGTGAAGGCAAGGCCAACCGGGTCTTCGCTA
CCATTATGCCGTTGGTGGCACTCTCTCCAGCGCTGGCGCCGTTGGTCGGTGCCTGGCTGTTGAACCACATGGGCTGGCGT
GCCATTTTTGCCGTGCTGCTGGGCATTACCGTCATTCTCCTGCTGCCGACTCTGCTGTTGAAAGAAAACGCTAAACCCTT
GCCTTCCGCAGAAAAGAAAAACAGCCTGACCTTCTGGCAACTGCTTAAATCCCCGGTGTTCAGCGGCAGCGTTACCATCT
TTGCCGCCTGCTCAGCCGGCTTCTTCGCCTGGCTGACCGGTTCACCCTTTATTCTTGGCGATATGGGGTACAGCCCAAAT
GATATCGGCCTGAGCTATGTGCCGCAGACCCTGGCCTTCCTGTTAGGGGGTTATGGCTGCCGCACCGCGTTAAATCGCAT
TAATGGCAACACCTTACTGCCGTGGCTGCTGGTAGCTTATGGCATCAGCATGGTGGCGTTATATCTGGTTGCCACGCTGA
CCGAGCCAACGCTCACCACGCTGCTGATCCCGTTCTGCGTGATGGCGCTGGTCAACGGTGCCAGCTACCCAATCGTAGTG
GCGAATGCGTTAACCCCGTTCCCGGAAGGCACAGGCAAAGCCGCAGCGCTGCAAAACACCCTGCAGTTGGGGCTGTGTTT
TGTCGCCAGCATGCTGGTATCGGCCTTTATCGAACAGCCGCTGTTGGCAACGGTGACGGTGATGGTTTCTACGGTAGTAT
TAGCCGCATTGGGCTATATGCTGCAACGGGGAAAAGTGATGGATGAACAGCAGGCGACGCGACAGGAACATGCTAACTCT
GCGTCATAA

Upstream 100 bases:

>100_bases
CAGCACCTCGCAAATATTACCGTTTCACAAGCAGAGATCCAGCCGGATACACTTGCCGGCGCTAAAAACCTGCGACAATA
AAATATTAATGAGAAATACC

Downstream 100 bases:

>100_bases
TTATATGTATTAATAATCACTTAAAGAATATTTTTGCCGAGTGCGATTTACAGTTGAGTAAGCGCCTCGGCAAGCCTATA
CTCAAAACGACCTTTTAAAA

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MRNSFGFMFYLAGLSMLGYLATDMYLPAFGIMQQDLQISAGAISASLSIFLAGFAFAQLLWGPLSDRLGRKPVLLIGLAL
FALGCMGMLWVQNAVQLWSLRFIQAIGVCSAAVTWQALVIDRYREGKANRVFATIMPLVALSPALAPLVGAWLLNHMGWR
AIFAVLLGITVILLLPTLLLKENAKPLPSAEKKNSLTFWQLLKSPVFSGSVTIFAACSAGFFAWLTGSPFILGDMGYSPN
DIGLSYVPQTLAFLLGGYGCRTALNRINGNTLLPWLLVAYGISMVALYLVATLTEPTLTTLLIPFCVMALVNGASYPIVV
ANALTPFPEGTGKAAALQNTLQLGLCFVASMLVSAFIEQPLLATVTVMVSTVVLAALGYMLQRGKVMDEQQATRQEHANS
AS

Sequences:

>Translated_402_residues
MRNSFGFMFYLAGLSMLGYLATDMYLPAFGIMQQDLQISAGAISASLSIFLAGFAFAQLLWGPLSDRLGRKPVLLIGLAL
FALGCMGMLWVQNAVQLWSLRFIQAIGVCSAAVTWQALVIDRYREGKANRVFATIMPLVALSPALAPLVGAWLLNHMGWR
AIFAVLLGITVILLLPTLLLKENAKPLPSAEKKNSLTFWQLLKSPVFSGSVTIFAACSAGFFAWLTGSPFILGDMGYSPN
DIGLSYVPQTLAFLLGGYGCRTALNRINGNTLLPWLLVAYGISMVALYLVATLTEPTLTTLLIPFCVMALVNGASYPIVV
ANALTPFPEGTGKAAALQNTLQLGLCFVASMLVSAFIEQPLLATVTVMVSTVVLAALGYMLQRGKVMDEQQATRQEHANS
AS
>Mature_402_residues
MRNSFGFMFYLAGLSMLGYLATDMYLPAFGIMQQDLQISAGAISASLSIFLAGFAFAQLLWGPLSDRLGRKPVLLIGLAL
FALGCMGMLWVQNAVQLWSLRFIQAIGVCSAAVTWQALVIDRYREGKANRVFATIMPLVALSPALAPLVGAWLLNHMGWR
AIFAVLLGITVILLLPTLLLKENAKPLPSAEKKNSLTFWQLLKSPVFSGSVTIFAACSAGFFAWLTGSPFILGDMGYSPN
DIGLSYVPQTLAFLLGGYGCRTALNRINGNTLLPWLLVAYGISMVALYLVATLTEPTLTTLLIPFCVMALVNGASYPIVV
ANALTPFPEGTGKAAALQNTLQLGLCFVASMLVSAFIEQPLLATVTVMVSTVVLAALGYMLQRGKVMDEQQATRQEHANS
AS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=404, Percent_Identity=62.6237623762376, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1788509, Length=368, Percent_Identity=26.6304347826087, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790794, Length=228, Percent_Identity=29.3859649122807, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787065, Length=239, Percent_Identity=28.4518828451883, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87082312, Length=326, Percent_Identity=23.6196319018405, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790146, Length=222, Percent_Identity=27.9279279279279, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319657, Length=204, Percent_Identity=28.921568627451, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322071, Length=169, Percent_Identity=24.8520710059172, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43163; Mature: 43163

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]