Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 157370385

GI number: 157370385

Start: 2341873

End: 2342223

Strand: Direct

Name: infC [H]

Synonym: Spro_2145

Alternate gene names: 157370385

Gene position: 2341873-2342223 (Clockwise)

Preceding gene: 157370384

Following gene: 157370386

Centisome position: 42.98

GC content: 47.86

Gene sequence:

>351_bases
ATGGATTACGGCAAATTCCTCTACGAGAAGAGCAAGTCGACAAAAGAACAGAAGAAGAAGCAAAAAGTTATTCAGGTCAA
GGAAATCAAATTCCGTCCTGGTACCGATGATGGCGACTATCAGGTAAAACTACGCAACCTGATTCGCTTTCTTGAAGATG
GCGATAAAGCCAAAATCACCCTGCGTTTCCGTGGGCGTGAGATGGCGCACCAACAGATCGGCATGGAAGTGCTTAACCGC
GTCCGTAAAGACCTGTGTGAAGATTCTGATTTGGCCATTGTCGAATCCTTCCCTACGAGGATCGAAGGCCGTCAGATGAT
CATGGTGCTCGCACCGAAGAAGAGGCAGTAA

Upstream 100 bases:

>100_bases
TGGTATTGTCAGTCTGAATGAAGCTCTTGAAAAAGCTGAGGAAGCGGGCGTTGATTTAGTAGAAATCAGCCCAAATGCCG
AACCGCCAGTTTGTCGAATC

Downstream 100 bases:

>100_bases
GGCCTCCAAGTAATAAAACTCACGCAGCGCTTGCGTTGTGTGGGTTTTATTCGCCTAACTGATTCGTTGTTTAACAATGC
GAAGTGGATTTAATTAAAAT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNR
VRKDLCEDSDLAIVESFPTRIEGRQMIMVLAPKKRQ

Sequences:

>Translated_116_residues
MDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNR
VRKDLCEDSDLAIVESFPTRIEGRQMIMVLAPKKRQ
>Mature_116_residues
MDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNR
VRKDLCEDSDLAIVESFPTRIEGRQMIMVLAPKKRQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=116, Percent_Identity=88.7931034482759, Blast_Score=180, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 13705; Mature: 13705

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKIT
CCHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCCCEEHHHHHHHHHCCCCCEEEE
LRFRGREMAHQQIGMEVLNRVRKDLCEDSDLAIVESFPTRIEGRQMIMVLAPKKRQ
EEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MDYGKFLYEKSKSTKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKIT
CCHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCCCEEHHHHHHHHHCCCCCEEEE
LRFRGREMAHQQIGMEVLNRVRKDLCEDSDLAIVESFPTRIEGRQMIMVLAPKKRQ
EEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8405963 [H]