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The map label for this gene is htpX [H]

Identifier: 157370360

GI number: 157370360

Start: 2315375

End: 2316253

Strand: Direct

Name: htpX [H]

Synonym: Spro_2120

Alternate gene names: 157370360

Gene position: 2315375-2316253 (Clockwise)

Preceding gene: 157370359

Following gene: 157370362

Centisome position: 42.49

GC content: 57.45

Gene sequence:

>879_bases
ATGATGCGTATAGCTCTGTTCCTGCTCACCAACCTGGCGGTGATGTTGGTTTTCGGGCTGGTGCTCAGCCTGACAGGAAT
CCAATCCAGTAGCGTTCAGGGCCTGATGATCATGGCCGGTCTGTTCGGCTTCGGCGGTTCGTTTGTTTCACTGCTGATGT
CCAAATGGATGGCGCTGCGCTCCGTCGGCGGGGAAGTGATTGAACAACCGCGTAACGAGACCGAAAACTGGCTGCTGGAA
ACGGTACGCCGTCAGTCGCAGCAGGCAGGCATTGCCATGCCGCAGGTGGCTATTTATCACGCACCAGACATTAACGCCTT
CGCCACCGGTGCGCGCCGTAATGCGTCACTGGTCGCCGTCAGCACCGGCCTGCTGCAAAGCATGAGCCGTGATGAAGCGG
AAGCGGTTATTGCCCACGAAATCAGCCACGTTGCCAATGGCGACATGGTCACCATGACGCTGATCCAGGGCATCGTGAAC
ACCTTCGTGATCTTCATCTCACGACTGATCGCACAGGCGGCCGCCGGCTTCCTGGGCAACCGTGACGGCGAAGGGGAAGG
CAACGGCAACCCGATGATCTACTTCGGCGTGTCGATGGTTCTGGAGCTGGTATTCGGCATCCTGGCCAGCATTATCACCA
TGTGGTTCTCGCGTCACCGTGAGTTCTACGCCGATGCAGGTTCTGCCAAACTGGTGGGCCGCGAGAAAATGATCGCGGCG
CTGCAACGGCTGAAAACCAGTTACGAGCCGCAGGAAGCGGGCAACATGATGGCGTTTTGCATCAACGGCAAATCCAAATC
GTTCAGCGAACTGTTCATGTCGCACCCGCCGCTCGATAAACGTATCGAAGCGCTGCGTTCAGGTCAGTACCTGAAGTAA

Upstream 100 bases:

>100_bases
GGTTAATGGCGTGCAACTCTTGAAACTGTGATGAATGCCCATACCATCTAGGGTATCCGAGGCAGCGTTTTGTTAACATT
TATGAGGAAGTAAACATTTT

Downstream 100 bases:

>100_bases
CCCTGAGAACGTTAAAAACCCCGGCTCGCCGGGGTTTTTTTATGTCCGTTATTTGGCTTGCCGGCTGCTTTCTGCCGGTT
GTGAGCAGGGTTGGGTAATG

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MMRIALFLLTNLAVMLVFGLVLSLTGIQSSSVQGLMIMAGLFGFGGSFVSLLMSKWMALRSVGGEVIEQPRNETENWLLE
TVRRQSQQAGIAMPQVAIYHAPDINAFATGARRNASLVAVSTGLLQSMSRDEAEAVIAHEISHVANGDMVTMTLIQGIVN
TFVIFISRLIAQAAAGFLGNRDGEGEGNGNPMIYFGVSMVLELVFGILASIITMWFSRHREFYADAGSAKLVGREKMIAA
LQRLKTSYEPQEAGNMMAFCINGKSKSFSELFMSHPPLDKRIEALRSGQYLK

Sequences:

>Translated_292_residues
MMRIALFLLTNLAVMLVFGLVLSLTGIQSSSVQGLMIMAGLFGFGGSFVSLLMSKWMALRSVGGEVIEQPRNETENWLLE
TVRRQSQQAGIAMPQVAIYHAPDINAFATGARRNASLVAVSTGLLQSMSRDEAEAVIAHEISHVANGDMVTMTLIQGIVN
TFVIFISRLIAQAAAGFLGNRDGEGEGNGNPMIYFGVSMVLELVFGILASIITMWFSRHREFYADAGSAKLVGREKMIAA
LQRLKTSYEPQEAGNMMAFCINGKSKSFSELFMSHPPLDKRIEALRSGQYLK
>Mature_292_residues
MMRIALFLLTNLAVMLVFGLVLSLTGIQSSSVQGLMIMAGLFGFGGSFVSLLMSKWMALRSVGGEVIEQPRNETENWLLE
TVRRQSQQAGIAMPQVAIYHAPDINAFATGARRNASLVAVSTGLLQSMSRDEAEAVIAHEISHVANGDMVTMTLIQGIVN
TFVIFISRLIAQAAAGFLGNRDGEGEGNGNPMIYFGVSMVLELVFGILASIITMWFSRHREFYADAGSAKLVGREKMIAA
LQRLKTSYEPQEAGNMMAFCINGKSKSFSELFMSHPPLDKRIEALRSGQYLK

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=293, Percent_Identity=87.7133105802048, Blast_Score=522, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31852; Mature: 31852

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRIALFLLTNLAVMLVFGLVLSLTGIQSSSVQGLMIMAGLFGFGGSFVSLLMSKWMALR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
SVGGEVIEQPRNETENWLLETVRRQSQQAGIAMPQVAIYHAPDINAFATGARRNASLVAV
HHCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCCCCCCCEEEEH
STGLLQSMSRDEAEAVIAHEISHVANGDMVTMTLIQGIVNTFVIFISRLIAQAAAGFLGN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RDGEGEGNGNPMIYFGVSMVLELVFGILASIITMWFSRHREFYADAGSAKLVGREKMIAA
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LQRLKTSYEPQEAGNMMAFCINGKSKSFSELFMSHPPLDKRIEALRSGQYLK
HHHHHHCCCHHHHCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMRIALFLLTNLAVMLVFGLVLSLTGIQSSSVQGLMIMAGLFGFGGSFVSLLMSKWMALR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
SVGGEVIEQPRNETENWLLETVRRQSQQAGIAMPQVAIYHAPDINAFATGARRNASLVAV
HHCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCCCCCCCEEEEH
STGLLQSMSRDEAEAVIAHEISHVANGDMVTMTLIQGIVNTFVIFISRLIAQAAAGFLGN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RDGEGEGNGNPMIYFGVSMVLELVFGILASIITMWFSRHREFYADAGSAKLVGREKMIAA
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LQRLKTSYEPQEAGNMMAFCINGKSKSFSELFMSHPPLDKRIEALRSGQYLK
HHHHHHCCCHHHHCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA