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The map label for this gene is icd [H]

Identifier: 157370290

GI number: 157370290

Start: 2243010

End: 2243162

Strand: Direct

Name: icd [H]

Synonym: Spro_2048

Alternate gene names: 157370290

Gene position: 2243010-2243162 (Clockwise)

Preceding gene: 157370289

Following gene: 157370291

Centisome position: 41.16

GC content: 51.63

Gene sequence:

>153_bases
ATGGGCTGGTTCGAAGCGGCTGACCTGATTGTTAAGGGCACTGAAGGCGCAATCGCCGCCAAGACCGTGACCTATGACTT
CGAACGCCTGATGGAAGGCGCTAAACTGCTGAAATGTTCAGAGTTTGGCGACGCTATCGTTAAACACATGTAA

Upstream 100 bases:

>100_bases
TACGAATTACCTAAAATGATACAACCACATAGATTAAATGTAGTTTTTATTATTATATTCAATTGGTTATGAACTATACT
GCAATCTACTGCTGCGTCAC

Downstream 100 bases:

>100_bases
TGGTGTTTTGCGTTTGAATAAGAACGGGAGCCTGATGGCTCCCGTTTTTTATTGTTCTTTCCAGTGACTATTCTAAAAGA
AGGGAATCATGAATAGAGTT

Product: isocitrate dehydrogenase

Products: NA

Alternate protein names: IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase [H]

Number of amino acids: Translated: 50; Mature: 49

Protein sequence:

>50_residues
MGWFEAADLIVKGTEGAIAAKTVTYDFERLMEGAKLLKCSEFGDAIVKHM

Sequences:

>Translated_50_residues
MGWFEAADLIVKGTEGAIAAKTVTYDFERLMEGAKLLKCSEFGDAIVKHM
>Mature_49_residues
GWFEAADLIVKGTEGAIAAKTVTYDFERLMEGAKLLKCSEFGDAIVKHM

Specific function: Unknown

COG id: COG0538

COG function: function code C; Isocitrate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate and isopropylmalate dehydrogenases family [H]

Homologues:

Organism=Escherichia coli, GI1787381, Length=50, Percent_Identity=86, Blast_Score=92, Evalue=9e-21,

Paralogues:

None

Copy number: 8180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019818
- InterPro:   IPR001804
- InterPro:   IPR004439 [H]

Pfam domain/function: PF00180 Iso_dh [H]

EC number: =1.1.1.42 [H]

Molecular weight: Translated: 5493; Mature: 5362

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWFEAADLIVKGTEGAIAAKTVTYDFERLMEGAKLLKCSEFGDAIVKHM
CCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GWFEAADLIVKGTEGAIAAKTVTYDFERLMEGAKLLKCSEFGDAIVKHM
CCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3112144; 8905232; 9278503; 9352899; 9298646; 2204109; 2682654; 10623532 [H]