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The map label for this gene is mocR [H]

Identifier: 157370259

GI number: 157370259

Start: 2211154

End: 2212671

Strand: Direct

Name: mocR [H]

Synonym: Spro_2017

Alternate gene names: 157370259

Gene position: 2211154-2212671 (Clockwise)

Preceding gene: 157370252

Following gene: 157370260

Centisome position: 40.58

GC content: 53.29

Gene sequence:

>1518_bases
ATGAAACACAGCGGTGACAGCCAGCAGGACGTTTCTCCAGATGCGATACAGGCAAGCTTTATTCAGCATTTACGACAAGG
AATGACGCGTAAGGCTGCGCTGCATCTGACAATCAAACAGCAGGTGACGGCGGGCGAACTGAGCTACCTGGCAAAGTTGC
CGCCCAGCCGGGTTCTGGCGGCTCGATTGGCGGTTTCACGCGATACCGTCGAACAGACCTATGCCCAATTGGAAGCGGAG
GGTTATATTGCCCGTGCCGTTGGGCGCGGTAGCTTTGTCAGCTACCAGCAAGACACCCTGATCGGTCGTGAACTGCTGGC
CACTGACAGCACCGACCAGGCCTTGCTGGTGGAGCGGGAGTTGAGTGCGCATGGCCGTTCCTTGCTGATTGCCGCCCATG
CTCCGCATACTCGCCGCAGCGGCTCATTGACCCCCTCATTGCCCGATTTGCGCTTGTTCCCCATCGACAGCTGGCTGCAA
CTGGAAAGACAGGCGGTGCGACAGGGGGCGGAATACCTGCTGGGTTACGCCGATCCTCAGGGGCTGGTGGAGTTGAGAGA
GGAAATCATCGAGTATCTGCGGCGCGAAAGAGGGGTTAAAGCCGGCACGGAACAGGTGATTGTGGTGACCAGTTCCCAGC
AGGCGCTCTCGCTGTGTACTCAGGTGCTGTTTAATCCCGGCGACCGGGTTTTTGTGGAAGAACCCGGCTATCAGGGCGCG
AAAAAGTTGGTTCAGTCGGCGGGATTAATCGCCCAGCCGATAGGGGTGGATCCCTGCGGTATGGATATTGATGCGTTAAT
AAACACCGAAGAGGGCGGACGGGGCGTTTATATTACGCCGTCCCACCATTATCCGCTGGGGCATTCACTCAGTATTGAAC
GAAGATTAAAACTGTTGGCATGGGCGCAGCGTGAAAAGGCCTGGATCCTTGAAGATGATTACGATTCTGAATTCAATTAT
AACGGCCTGACTACCGCAGCGTTGCAGGGGCTGGATCAATATCAGCGAACTTTATATATCGGTACTTTCAGCAAAAGCCT
TTTTCCAGGATTGCGCATTGGTTTTCTTATTGTTCCGCCACAGCTAATTAAACCCATGGTGGCCGCCAAACAATTCCAGG
ATGGATATACTTCGGCCTTGCCGCAAATGACGTTATTTAAATTTATCAATGAAGATTTCTATGCCGAACATTTAAGGAAT
ATGCGCAAGATATATCAGGCCCGGCTGGAGATTTTGCATGCGGCGGTGCATCAGTATCTTGCCGCCTGGACTCAACCACG
GTTACCGCAGGGCGGGCTGCAATTGGTTTGCCCATTGAAGGACGCGGCTACCGAGCGGCGGTTGATTCAGGCTGCCGCAG
CGCAGGACATGAGGGTCTACGGGCTGATTGATTTTTATACCCATTCGCCAAGTGAAGGGGCGTTGGTATTTGGCTTTGCT
GCCTATACACCCGACGAGATTGTAAAATTTATCAAAAAGTTATCCTGCATTTTTGATTCGTTACCTGTGCCAGGCTAA

Upstream 100 bases:

>100_bases
AACATTTTGTTCACAACTAGATTGATTTAGATCAATTATTCAACATCTCCAGCGCTGGTTTATCCTCCAGCGGTACGGAA
GATCTCTGAGCAGGAATAGC

Downstream 100 bases:

>100_bases
AGGCAGTCAGGTCGCTAAAATTGGTCTGCTCGTTGTTATTAATTGGTCTGTGTTCAGGCTGCGTTGACCGGTGTATCCTG
TTGGTATTACGTTACTTTTT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MKHSGDSQQDVSPDAIQASFIQHLRQGMTRKAALHLTIKQQVTAGELSYLAKLPPSRVLAARLAVSRDTVEQTYAQLEAE
GYIARAVGRGSFVSYQQDTLIGRELLATDSTDQALLVERELSAHGRSLLIAAHAPHTRRSGSLTPSLPDLRLFPIDSWLQ
LERQAVRQGAEYLLGYADPQGLVELREEIIEYLRRERGVKAGTEQVIVVTSSQQALSLCTQVLFNPGDRVFVEEPGYQGA
KKLVQSAGLIAQPIGVDPCGMDIDALINTEEGGRGVYITPSHHYPLGHSLSIERRLKLLAWAQREKAWILEDDYDSEFNY
NGLTTAALQGLDQYQRTLYIGTFSKSLFPGLRIGFLIVPPQLIKPMVAAKQFQDGYTSALPQMTLFKFINEDFYAEHLRN
MRKIYQARLEILHAAVHQYLAAWTQPRLPQGGLQLVCPLKDAATERRLIQAAAAQDMRVYGLIDFYTHSPSEGALVFGFA
AYTPDEIVKFIKKLSCIFDSLPVPG

Sequences:

>Translated_505_residues
MKHSGDSQQDVSPDAIQASFIQHLRQGMTRKAALHLTIKQQVTAGELSYLAKLPPSRVLAARLAVSRDTVEQTYAQLEAE
GYIARAVGRGSFVSYQQDTLIGRELLATDSTDQALLVERELSAHGRSLLIAAHAPHTRRSGSLTPSLPDLRLFPIDSWLQ
LERQAVRQGAEYLLGYADPQGLVELREEIIEYLRRERGVKAGTEQVIVVTSSQQALSLCTQVLFNPGDRVFVEEPGYQGA
KKLVQSAGLIAQPIGVDPCGMDIDALINTEEGGRGVYITPSHHYPLGHSLSIERRLKLLAWAQREKAWILEDDYDSEFNY
NGLTTAALQGLDQYQRTLYIGTFSKSLFPGLRIGFLIVPPQLIKPMVAAKQFQDGYTSALPQMTLFKFINEDFYAEHLRN
MRKIYQARLEILHAAVHQYLAAWTQPRLPQGGLQLVCPLKDAATERRLIQAAAAQDMRVYGLIDFYTHSPSEGALVFGFA
AYTPDEIVKFIKKLSCIFDSLPVPG
>Mature_505_residues
MKHSGDSQQDVSPDAIQASFIQHLRQGMTRKAALHLTIKQQVTAGELSYLAKLPPSRVLAARLAVSRDTVEQTYAQLEAE
GYIARAVGRGSFVSYQQDTLIGRELLATDSTDQALLVERELSAHGRSLLIAAHAPHTRRSGSLTPSLPDLRLFPIDSWLQ
LERQAVRQGAEYLLGYADPQGLVELREEIIEYLRRERGVKAGTEQVIVVTSSQQALSLCTQVLFNPGDRVFVEEPGYQGA
KKLVQSAGLIAQPIGVDPCGMDIDALINTEEGGRGVYITPSHHYPLGHSLSIERRLKLLAWAQREKAWILEDDYDSEFNY
NGLTTAALQGLDQYQRTLYIGTFSKSLFPGLRIGFLIVPPQLIKPMVAAKQFQDGYTSALPQMTLFKFINEDFYAEHLRN
MRKIYQARLEILHAAVHQYLAAWTQPRLPQGGLQLVCPLKDAATERRLIQAAAAQDMRVYGLIDFYTHSPSEGALVFGFA
AYTPDEIVKFIKKLSCIFDSLPVPG

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=343, Percent_Identity=22.7405247813411, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI33469970, Length=343, Percent_Identity=22.7405247813411, Blast_Score=93, Evalue=7e-19,
Organism=Escherichia coli, GI1790797, Length=421, Percent_Identity=27.790973871734, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1787710, Length=404, Percent_Identity=25.4950495049505, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56207; Mature: 56207

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHSGDSQQDVSPDAIQASFIQHLRQGMTRKAALHLTIKQQVTAGELSYLAKLPPSRVLA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEEHHHCCHHHHHHHHHCCHHHHHH
ARLAVSRDTVEQTYAQLEAEGYIARAVGRGSFVSYQQDTLIGRELLATDSTDQALLVERE
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHH
LSAHGRSLLIAAHAPHTRRSGSLTPSLPDLRLFPIDSWLQLERQAVRQGAEYLLGYADPQ
HHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHEECCCCCH
GLVELREEIIEYLRRERGVKAGTEQVIVVTSSQQALSLCTQVLFNPGDRVFVEEPGYQGA
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCHHH
KKLVQSAGLIAQPIGVDPCGMDIDALINTEEGGRGVYITPSHHYPLGHSLSIERRLKLLA
HHHHHHCCCEECCCCCCCCCCCHHHEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHHHH
WAQREKAWILEDDYDSEFNYNGLTTAALQGLDQYQRTLYIGTFSKSLFPGLRIGFLIVPP
HHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECHHHHCCCCEEEEEEECH
QLIKPMVAAKQFQDGYTSALPQMTLFKFINEDFYAEHLRNMRKIYQARLEILHAAVHQYL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAWTQPRLPQGGLQLVCPLKDAATERRLIQAAAAQDMRVYGLIDFYTHSPSEGALVFGFA
HHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCEEEEEE
AYTPDEIVKFIKKLSCIFDSLPVPG
CCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKHSGDSQQDVSPDAIQASFIQHLRQGMTRKAALHLTIKQQVTAGELSYLAKLPPSRVLA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEEHHHCCHHHHHHHHHCCHHHHHH
ARLAVSRDTVEQTYAQLEAEGYIARAVGRGSFVSYQQDTLIGRELLATDSTDQALLVERE
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHH
LSAHGRSLLIAAHAPHTRRSGSLTPSLPDLRLFPIDSWLQLERQAVRQGAEYLLGYADPQ
HHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHEECCCCCH
GLVELREEIIEYLRRERGVKAGTEQVIVVTSSQQALSLCTQVLFNPGDRVFVEEPGYQGA
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCHHH
KKLVQSAGLIAQPIGVDPCGMDIDALINTEEGGRGVYITPSHHYPLGHSLSIERRLKLLA
HHHHHHCCCEECCCCCCCCCCCHHHEEECCCCCCEEEECCCCCCCCCCCCCHHHHHHHHH
WAQREKAWILEDDYDSEFNYNGLTTAALQGLDQYQRTLYIGTFSKSLFPGLRIGFLIVPP
HHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECHHHHCCCCEEEEEEECH
QLIKPMVAAKQFQDGYTSALPQMTLFKFINEDFYAEHLRNMRKIYQARLEILHAAVHQYL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAWTQPRLPQGGLQLVCPLKDAATERRLIQAAAAQDMRVYGLIDFYTHSPSEGALVFGFA
HHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCEEEEEE
AYTPDEIVKFIKKLSCIFDSLPVPG
CCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]