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The map label for this gene is nagK [H]

Identifier: 157370246

GI number: 157370246

Start: 2195001

End: 2195921

Strand: Direct

Name: nagK [H]

Synonym: Spro_2004

Alternate gene names: 157370246

Gene position: 2195001-2195921 (Clockwise)

Preceding gene: 157370245

Following gene: 157370247

Centisome position: 40.28

GC content: 57.76

Gene sequence:

>921_bases
ATGTACTACGGTTTCGATATGGGCGGCACCAAGATTGAGCTGGGCGTATTCGACGCAGACCTGCAGCGCATTTGGCAAAA
AAGAGTGCCGACGCCGCGTGAAGATTATCAGCAACTGCTGGCGACGTTGCGCGACCTGACCTTTGAAGCGGATGCGTTCT
GCGGCCAGAAGGGCATGGTCGGCATCGGCATTCCGGGTCTGCCCAACGATGACGACGGCACGGTGTTCACCGCCAACGTG
CCGGCGGCGATGGGGCAGAAGCTGCCGCATGACCTGGCCGAACTGATTGGCCGCGAAGTACGCATTGATAATGACGCCAA
CTGCTTTGCACTGTCGGAAGCCTGGGACGAAGAATTCTGTCACTATCCGACGGTGTTGGGCATCATTCTCGGCACCGGGG
TTGGCGGCGGGCTAATCGTCGATGGCAAGGTGGTCTCCGGGCGTAATTATATCGCCGGTGAATTCGGCCACTTCCGCCTG
CCGGTAGATGCCCTTGAGGTGCTGGGGCGTGATATTCCTCGCGTTCCTTGTGGTTGCGGTCATCAGGGTTGCATCGAAAA
TTACATTTCCGGCCGCGGTTTTGAGTGGATGTACGCCCACTTTTACCAGCAGCACTTGCCTGCGCAGCAGATCATTGCGC
ATTATCAGTCGGGGGAGCCGCAGGCCGTGGCTCACGTCGAACGTTTTATGGACGTGCTGGCGATATGTCTGGGTAATCTG
CTGACCATCATCGACCCTCATCTGGTGGTGATTGGTGGCGGTTTGTCGAACTTTGAAGCGATCTACCAGGAATTACCGCA
GCGTTTGCCGGCGCATCTGTTGCGGGTGGCCAAGTTGCCACGGATTGAAAAGGCGCGCTACGGCGATGCCGGTGGGGTCC
GCGGAGCTGCGTTCCTCAATTTGGTCAACAGGGAAAAGTAA

Upstream 100 bases:

>100_bases
CGTGCCAGCCGTATCGATCCGGCACGAGTGTTGAGCGGACAATAATCAAAATCAGGGGAGGCAGAGATGCCGCCCCATTT
TTTTAGCCTGAGGGTGGGTT

Downstream 100 bases:

>100_bases
GGAGAGAGTTAATGCACACTCGCCATCGGCTGTGTCAGTTTCGCAAGAGTAAGCATGTGCTGCATCAGCGCTTTCGTTCG
CGGATATTTCATCGCGACAC

Product: N-acetyl-D-glucosamine kinase

Products: NA

Alternate protein names: GlcNAc kinase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MYYGFDMGGTKIELGVFDADLQRIWQKRVPTPREDYQQLLATLRDLTFEADAFCGQKGMVGIGIPGLPNDDDGTVFTANV
PAAMGQKLPHDLAELIGREVRIDNDANCFALSEAWDEEFCHYPTVLGIILGTGVGGGLIVDGKVVSGRNYIAGEFGHFRL
PVDALEVLGRDIPRVPCGCGHQGCIENYISGRGFEWMYAHFYQQHLPAQQIIAHYQSGEPQAVAHVERFMDVLAICLGNL
LTIIDPHLVVIGGGLSNFEAIYQELPQRLPAHLLRVAKLPRIEKARYGDAGGVRGAAFLNLVNREK

Sequences:

>Translated_306_residues
MYYGFDMGGTKIELGVFDADLQRIWQKRVPTPREDYQQLLATLRDLTFEADAFCGQKGMVGIGIPGLPNDDDGTVFTANV
PAAMGQKLPHDLAELIGREVRIDNDANCFALSEAWDEEFCHYPTVLGIILGTGVGGGLIVDGKVVSGRNYIAGEFGHFRL
PVDALEVLGRDIPRVPCGCGHQGCIENYISGRGFEWMYAHFYQQHLPAQQIIAHYQSGEPQAVAHVERFMDVLAICLGNL
LTIIDPHLVVIGGGLSNFEAIYQELPQRLPAHLLRVAKLPRIEKARYGDAGGVRGAAFLNLVNREK
>Mature_306_residues
MYYGFDMGGTKIELGVFDADLQRIWQKRVPTPREDYQQLLATLRDLTFEADAFCGQKGMVGIGIPGLPNDDDGTVFTANV
PAAMGQKLPHDLAELIGREVRIDNDANCFALSEAWDEEFCHYPTVLGIILGTGVGGGLIVDGKVVSGRNYIAGEFGHFRL
PVDALEVLGRDIPRVPCGCGHQGCIENYISGRGFEWMYAHFYQQHLPAQQIIAHYQSGEPQAVAHVERFMDVLAICLGNL
LTIIDPHLVVIGGGLSNFEAIYQELPQRLPAHLLRVAKLPRIEKARYGDAGGVRGAAFLNLVNREK

Specific function: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family. NagK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787363, Length=303, Percent_Identity=64.3564356435644, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI87081733, Length=300, Percent_Identity=39.6666666666667, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1790522, Length=312, Percent_Identity=24.6794871794872, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082127, Length=193, Percent_Identity=25.3886010362694, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.59 [H]

Molecular weight: Translated: 33647; Mature: 33647

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYGFDMGGTKIELGVFDADLQRIWQKRVPTPREDYQQLLATLRDLTFEADAFCGQKGMV
CCEEECCCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCE
GIGIPGLPNDDDGTVFTANVPAAMGQKLPHDLAELIGREVRIDNDANCFALSEAWDEEFC
EECCCCCCCCCCCEEEEECCCHHHHHCCHHHHHHHCCCEEEECCCCCEEEEHHHHHHHHH
HYPTVLGIILGTGVGGGLIVDGKVVSGRNYIAGEFGHFRLPVDALEVLGRDIPRVPCGCG
HHHHHHHHHHHCCCCCCEEECCEEECCCCCEECCCCCEECCHHHHHHHCCCCCCCCCCCC
HQGCIENYISGRGFEWMYAHFYQQHLPAQQIIAHYQSGEPQAVAHVERFMDVLAICLGNL
CHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LTIIDPHLVVIGGGLSNFEAIYQELPQRLPAHLLRVAKLPRIEKARYGDAGGVRGAAFLN
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHH
LVNREK
HHHCCC
>Mature Secondary Structure
MYYGFDMGGTKIELGVFDADLQRIWQKRVPTPREDYQQLLATLRDLTFEADAFCGQKGMV
CCEEECCCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCE
GIGIPGLPNDDDGTVFTANVPAAMGQKLPHDLAELIGREVRIDNDANCFALSEAWDEEFC
EECCCCCCCCCCCEEEEECCCHHHHHCCHHHHHHHCCCEEEECCCCCEEEEHHHHHHHHH
HYPTVLGIILGTGVGGGLIVDGKVVSGRNYIAGEFGHFRLPVDALEVLGRDIPRVPCGCG
HHHHHHHHHHHCCCCCCEEECCEEECCCCCEECCCCCEECCHHHHHHHCCCCCCCCCCCC
HQGCIENYISGRGFEWMYAHFYQQHLPAQQIIAHYQSGEPQAVAHVERFMDVLAICLGNL
CHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LTIIDPHLVVIGGGLSNFEAIYQELPQRLPAHLLRVAKLPRIEKARYGDAGGVRGAAFLN
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHH
LVNREK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA