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The map label for this gene is ycfH [H]

Identifier: 157370155

GI number: 157370155

Start: 2096159

End: 2096935

Strand: Direct

Name: ycfH [H]

Synonym: Spro_1913

Alternate gene names: 157370155

Gene position: 2096159-2096935 (Clockwise)

Preceding gene: 157370154

Following gene: 157370156

Centisome position: 38.47

GC content: 55.21

Gene sequence:

>777_bases
ATGTTGTTAGTAGATTCTCATTGTCACCTCGACGGCCTGGATTACCAAACTCTGCATCAAAATGTGGATGATGCTTTGGC
GAAGGCCAAGGCGCGCGATGTCGGTTACGTGCTGGCGGTGGCCACCACTTTGCCGGGCTATCAGGCGATGACGCAATTGA
TTGGCCAACGCGATGACGTGGCCTTCTCCTGCGGGGTGCATCCGCTCAATCTGGAGGGGGGCTACGACTACGCTGAGCTG
CGCCGTTTGGCGGCAGCAGAGCAGGTGGTGGCACTAGGTGAAACCGGGCTGGACTACTTCTATCAGAAAGACAATCTTGA
GCTGCAGCAAGCGTCATTCCGTGAACATATCCGTATTGGCCGCGATCTGAACAAGCCGGTGATCGTGCATACCCGCGATG
CACGGGAAGACACACTGGCTATTCTGCGTGAAGAAAATGCTCAGGATTGTGGCGGTGTATTGCACTGCTTCACCGAAGAT
TGCGCTACCGCTGAGGCGTTGCTGGATCTGGGGTTCTACATTTCTTTCTCAGGTATCCTGACCTTCCGCAATGCAGAGCA
ACTGCGTGAAGTGGCGCGCTATGTGCCACTGGATCGTATTCTGGTGGAAACCGACTCGCCGTATCTGGCTCCGGTGCCGC
ATCGCGGCAAAGAAAACCAACCTGCCTATGTGCGCGATGTGGCTGAATACATGGCGGTATTGAAGGGCGTGAGCCTGGAA
ACGCTGGCCGAAGCCACCACCGCCAACTTTTCACGCTTATTTCACATCGAACTCTAA

Upstream 100 bases:

>100_bases
ACCGCGAACTGCTGCTGACCGAACAGTTACTTGGCTGGGAGCAGTTGCTCGTCGCTACCGGCTATTCCCACCCTCATTCG
CTGTAAAAGAGTTAAATATT

Downstream 100 bases:

>100_bases
TCTTTGGCCTAGGCTATAGCTGTGGTTAACGAAATCTGAATTCTTTTTAAGCTCGTAATTAATCGCCGAAACGGGTAATG
TTCCCACCCGTTTTTCGGGC

Product: putative metallodependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLLVDSHCHLDGLDYQTLHQNVDDALAKAKARDVGYVLAVATTLPGYQAMTQLIGQRDDVAFSCGVHPLNLEGGYDYAEL
RRLAAAEQVVALGETGLDYFYQKDNLELQQASFREHIRIGRDLNKPVIVHTRDAREDTLAILREENAQDCGGVLHCFTED
CATAEALLDLGFYISFSGILTFRNAEQLREVARYVPLDRILVETDSPYLAPVPHRGKENQPAYVRDVAEYMAVLKGVSLE
TLAEATTANFSRLFHIEL

Sequences:

>Translated_258_residues
MLLVDSHCHLDGLDYQTLHQNVDDALAKAKARDVGYVLAVATTLPGYQAMTQLIGQRDDVAFSCGVHPLNLEGGYDYAEL
RRLAAAEQVVALGETGLDYFYQKDNLELQQASFREHIRIGRDLNKPVIVHTRDAREDTLAILREENAQDCGGVLHCFTED
CATAEALLDLGFYISFSGILTFRNAEQLREVARYVPLDRILVETDSPYLAPVPHRGKENQPAYVRDVAEYMAVLKGVSLE
TLAEATTANFSRLFHIEL
>Mature_258_residues
MLLVDSHCHLDGLDYQTLHQNVDDALAKAKARDVGYVLAVATTLPGYQAMTQLIGQRDDVAFSCGVHPLNLEGGYDYAEL
RRLAAAEQVVALGETGLDYFYQKDNLELQQASFREHIRIGRDLNKPVIVHTRDAREDTLAILREENAQDCGGVLHCFTED
CATAEALLDLGFYISFSGILTFRNAEQLREVARYVPLDRILVETDSPYLAPVPHRGKENQPAYVRDVAEYMAVLKGVSLE
TLAEATTANFSRLFHIEL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=31.4606741573034, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=31.0861423220974, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=31.3868613138686, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=30.3501945525292, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI225903424, Length=268, Percent_Identity=28.3582089552239, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=30.3030303030303, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI225903439, Length=193, Percent_Identity=25.9067357512953, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI14042943, Length=193, Percent_Identity=25.9067357512953, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=76.2645914396887, Blast_Score=402, Evalue=1e-114,
Organism=Escherichia coli, GI48994985, Length=244, Percent_Identity=33.6065573770492, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=28.1853281853282, Blast_Score=102, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17559024, Length=284, Percent_Identity=26.056338028169, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71980746, Length=270, Percent_Identity=27.037037037037, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17565396, Length=301, Percent_Identity=25.5813953488372, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17543026, Length=189, Percent_Identity=29.1005291005291, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648690, Length=287, Percent_Identity=25.7839721254355, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI221330018, Length=206, Percent_Identity=32.5242718446602, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24586117, Length=206, Percent_Identity=32.5242718446602, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28786; Mature: 28786

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVDSHCHLDGLDYQTLHQNVDDALAKAKARDVGYVLAVATTLPGYQAMTQLIGQRDDV
CEEECCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHCCCCCE
AFSCGVHPLNLEGGYDYAELRRLAAAEQVVALGETGLDYFYQKDNLELQQASFREHIRIG
EEECCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCHHHHHHHHHHHHC
RDLNKPVIVHTRDAREDTLAILREENAQDCGGVLHCFTEDCATAEALLDLGFYISFSGIL
CCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHEE
TFRNAEQLREVARYVPLDRILVETDSPYLAPVPHRGKENQPAYVRDVAEYMAVLKGVSLE
EECCHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHH
TLAEATTANFSRLFHIEL
HHHHHHHCCCEEEEEEEC
>Mature Secondary Structure
MLLVDSHCHLDGLDYQTLHQNVDDALAKAKARDVGYVLAVATTLPGYQAMTQLIGQRDDV
CEEECCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHCCCCCE
AFSCGVHPLNLEGGYDYAELRRLAAAEQVVALGETGLDYFYQKDNLELQQASFREHIRIG
EEECCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCHHHHHHHHHHHHC
RDLNKPVIVHTRDAREDTLAILREENAQDCGGVLHCFTEDCATAEALLDLGFYISFSGIL
CCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHEE
TFRNAEQLREVARYVPLDRILVETDSPYLAPVPHRGKENQPAYVRDVAEYMAVLKGVSLE
EECCHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHH
TLAEATTANFSRLFHIEL
HHHHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]