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The map label for this gene is yclF [H]

Identifier: 157370123

GI number: 157370123

Start: 2066126

End: 2067679

Strand: Reverse

Name: yclF [H]

Synonym: Spro_1881

Alternate gene names: 157370123

Gene position: 2067679-2066126 (Counterclockwise)

Preceding gene: 157370124

Following gene: 157370118

Centisome position: 37.95

GC content: 57.53

Gene sequence:

>1554_bases
ATGCAATCCTCTGTTAATAACCAAGAAAGCCGGACCTTCTTCGGCCACCCTTATCCGCTGGGATCCCTGTTCTTTACCGA
AATGTGGGAGCGGTTCTCGTTTTACGGCATTCGCCCATTACTGATCCTGTTTATGGCCGCGACGGTCTACGACGGCGGCA
TGGGGCTGGCACGTGAGAATGCCTCGGCAATTGTCGGTATTTTTGCCGGCAGCATGTATCTGGCGGCCCTGCCGGGCGGC
TGGTTGGCCGATAACTGGCTGGGCCAGCAAAAAGCGGTCTGGTACGGCTCGATTCTGATCGCTCTCGGCCACCTGTCGAT
CGCGCTGTCCGCCTTTATGGGCAACAACCTGTTCTTCATCGGCCTGATGTTTATTGTGTTGGGTTCCGGCCTGTTCAAAA
CCTGTATCTCGGTGATGGTCGGTACGCTCTACAAGAAAGGCGACAACCGCCGCGACGGTGGCTTCTCGCTGTTCTATATG
GGCATCAACATGGGCTCGTTTATCGCCCCGCTGATCTCTGGCTGGCTGATTCGATCCCACGGCTGGCACTGGGGCTTCGG
CATCGGTGGTATCGGTATGCTGGTGGCGTTGGTGATCTTCCGCGTCTTTGCCGTACCGGCAATGAAGCGCTATGACAGCG
AAGTGGGCCTGGACTCCACCTGGAACAGCCCGGTCGCCAAGAAAAACGGTGTCGGTGCCTGGCTGATTGCGCTGGCGGTC
GGCGTGGCAGTGGTTATCACCCTGATTGCCCAGAGCATCATTGTGATTAACCCGGTAGCCGTGGCCAGTATGCTGGTTTA
CGTGATTGCTGCTTCGGTCACCCTGTACTTCATTTATCTGTTTGTGTTTGCCGGTCTGAGCCGTAAAGAGCGCGCCCGCC
TGTTGGTCTGCTTTATCCTGCTGGTGTCAGCGGCCTTCTTCTGGTCAGCCTTCGAGCAGAAACCGACCTCGTTCAACCTG
TTCGCCAACGACTATACCAACCGGATGATTGGCGACTTCGAGATCCCGGCGGTGTGGTTCCAGTCCATCAACGCCCTGTT
CATTATCCTGCTGGCACCGGTATTTAGCTGGGCATGGCCGGCTCTGGCGCGTAATAAAGTGCGCCTGAGCAGTATCACCA
AGTTTGTTATCGGTATTCTGTTTGCCGCTGCGGGCTTTGGCCTGATGATGCTGGCCGCACAGAACGTGCTGAGCAACGGT
GGTGCCGGCGTATCTCCGTTGTGGCTGGTGGGCAGTATTTTGATGCTGACGCTGGGCGAACTGTGCCTTAGCCCGATTGG
GCTGGCAACCATGACCCTGCTGGCACCGGAAAGAATGCGCGGCCAAATGATGGGCCTGTGGTTCTGCGCCAGCGCATTGG
GTAACCTGGCGGCCGGTCTGATTGGCGGCCATGTTAAAGCCGACCAGCTGGACATGCTGCCAGACCTGTTCGCACGCTGC
TCGATTGCCCTGCTGATCTGTGCTGCGGTGCTGACTCTGCTGATCGTCCCGATCCGCCGGATGATGGAAAACACTCAGGG
TAAAAGCGCACAGAAACCGGCAACCAACGCCTGA

Upstream 100 bases:

>100_bases
TTGTCGGGTAATCCGCACTGGGTGGATCACCTTCCTTAAATACACATACATACCACAGTATAAGCTGCATAAATGCGGCG
CATTTTATTGGGAAGACGTT

Downstream 100 bases:

>100_bases
TAACCGTTTCGCTTTACCCTTCAGCCAGCGCCCGGTGCGCTGGCTTTTTTATTGTTCCCACGCCCGCTGTTGTAACACCA
CCCGGTAGCCGTCCAGGTCT

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MQSSVNNQESRTFFGHPYPLGSLFFTEMWERFSFYGIRPLLILFMAATVYDGGMGLARENASAIVGIFAGSMYLAALPGG
WLADNWLGQQKAVWYGSILIALGHLSIALSAFMGNNLFFIGLMFIVLGSGLFKTCISVMVGTLYKKGDNRRDGGFSLFYM
GINMGSFIAPLISGWLIRSHGWHWGFGIGGIGMLVALVIFRVFAVPAMKRYDSEVGLDSTWNSPVAKKNGVGAWLIALAV
GVAVVITLIAQSIIVINPVAVASMLVYVIAASVTLYFIYLFVFAGLSRKERARLLVCFILLVSAAFFWSAFEQKPTSFNL
FANDYTNRMIGDFEIPAVWFQSINALFIILLAPVFSWAWPALARNKVRLSSITKFVIGILFAAAGFGLMMLAAQNVLSNG
GAGVSPLWLVGSILMLTLGELCLSPIGLATMTLLAPERMRGQMMGLWFCASALGNLAAGLIGGHVKADQLDMLPDLFARC
SIALLICAAVLTLLIVPIRRMMENTQGKSAQKPATNA

Sequences:

>Translated_517_residues
MQSSVNNQESRTFFGHPYPLGSLFFTEMWERFSFYGIRPLLILFMAATVYDGGMGLARENASAIVGIFAGSMYLAALPGG
WLADNWLGQQKAVWYGSILIALGHLSIALSAFMGNNLFFIGLMFIVLGSGLFKTCISVMVGTLYKKGDNRRDGGFSLFYM
GINMGSFIAPLISGWLIRSHGWHWGFGIGGIGMLVALVIFRVFAVPAMKRYDSEVGLDSTWNSPVAKKNGVGAWLIALAV
GVAVVITLIAQSIIVINPVAVASMLVYVIAASVTLYFIYLFVFAGLSRKERARLLVCFILLVSAAFFWSAFEQKPTSFNL
FANDYTNRMIGDFEIPAVWFQSINALFIILLAPVFSWAWPALARNKVRLSSITKFVIGILFAAAGFGLMMLAAQNVLSNG
GAGVSPLWLVGSILMLTLGELCLSPIGLATMTLLAPERMRGQMMGLWFCASALGNLAAGLIGGHVKADQLDMLPDLFARC
SIALLICAAVLTLLIVPIRRMMENTQGKSAQKPATNA
>Mature_517_residues
MQSSVNNQESRTFFGHPYPLGSLFFTEMWERFSFYGIRPLLILFMAATVYDGGMGLARENASAIVGIFAGSMYLAALPGG
WLADNWLGQQKAVWYGSILIALGHLSIALSAFMGNNLFFIGLMFIVLGSGLFKTCISVMVGTLYKKGDNRRDGGFSLFYM
GINMGSFIAPLISGWLIRSHGWHWGFGIGGIGMLVALVIFRVFAVPAMKRYDSEVGLDSTWNSPVAKKNGVGAWLIALAV
GVAVVITLIAQSIIVINPVAVASMLVYVIAASVTLYFIYLFVFAGLSRKERARLLVCFILLVSAAFFWSAFEQKPTSFNL
FANDYTNRMIGDFEIPAVWFQSINALFIILLAPVFSWAWPALARNKVRLSSITKFVIGILFAAAGFGLMMLAAQNVLSNG
GAGVSPLWLVGSILMLTLGELCLSPIGLATMTLLAPERMRGQMMGLWFCASALGNLAAGLIGGHVKADQLDMLPDLFARC
SIALLICAAVLTLLIVPIRRMMENTQGKSAQKPATNA

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=218, Percent_Identity=30.7339449541284, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI226371746, Length=205, Percent_Identity=32.1951219512195, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI226371748, Length=198, Percent_Identity=29.7979797979798, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790572, Length=492, Percent_Identity=28.4552845528455, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1787922, Length=516, Percent_Identity=27.7131782945736, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1789911, Length=516, Percent_Identity=28.2945736434109, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1786927, Length=450, Percent_Identity=28.8888888888889, Blast_Score=170, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71987453, Length=393, Percent_Identity=25.6997455470738, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17569141, Length=405, Percent_Identity=23.9506172839506, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571102, Length=206, Percent_Identity=30.5825242718447, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571100, Length=206, Percent_Identity=30.5825242718447, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571098, Length=206, Percent_Identity=30.5825242718447, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24639583, Length=201, Percent_Identity=29.3532338308458, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24639585, Length=201, Percent_Identity=29.3532338308458, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24639581, Length=201, Percent_Identity=29.3532338308458, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 56058; Mature: 56058

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]