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The map label for this gene is licH [H]

Identifier: 157370099

GI number: 157370099

Start: 2039048

End: 2040349

Strand: Direct

Name: licH [H]

Synonym: Spro_1857

Alternate gene names: 157370099

Gene position: 2039048-2040349 (Clockwise)

Preceding gene: 157370098

Following gene: 157370100

Centisome position: 37.42

GC content: 56.91

Gene sequence:

>1302_bases
ATGACTAAAATCACCGTAATCGGCGGGGGCAGCAGCTACACGCCGGAGTTGGTCGAAGGATTGATTGCGCATTATCAGGA
CGTTCCTTTAACCGAGCTGGCACTGGTCGATGTGGAGTCCGGCCGTGAGAAAGTGGGCATCATTGCCGAGCTGACCAAAA
GAATGCTCAAGCGCAATGGGCTGGAGCAGGTAGTGGTTTCGGTGCATTTCACTCTGGAGCCGGCCATTCGCGGTGCCAGT
TTTGTGCTGACTCAGCTGCGAGTGGGGCAACTGGCCGCCCGTGCGGCCGATGAGCGTCTGGGGCTGAAATACCAGCGTCT
GGGTCAGGAAACCACCGGTGTCGGCGGTTTTGCCAAGGCGTTACGCACCATCCCGGTGATGTTGGAGGTGGCACGCGTGG
TGGAGGCGGTGGCGCCGGATGCCTGGATTATCAACTTCACTAACCCGGCGGGGATCGTTACCGAAGCGGTTTCGCGTTAC
AGCAAGGCGAAGATTATTGGGTTGTGCAACGTGCCGATCACCATGCATCACATGATCGCCGATATGCTGAAAGCGCCACA
CGATCAGGTAGACCTGCGGTTTGCCGGGCTGAACCATATGGTGTGGGTGCATCAGGTGACACAAAGCGGCAAGGATGTGA
CCGCCAAAGTGCTGGAAATGTTAAGCAATGGCGAAACGTTGTCGATGAACAACATCAAAGACCTGCCGTGGCCTCCGGCA
TTTCTGCAAGCGCTGGGGGCAATCCCTTGTCCGTATCACCGCTATTTTTATCAGACCGCCGGCATGCTGGAAGAAGAGCT
GGAAGCGGCTGCCGCACAGGGGACCCGTGCCGAGCAGGTGATGAAGGTAGAAGCGGAGTTATTTGCCTTATATGCCGATC
CGACGCTGGATAAAAAACCGGAGCAACTGAGTTTCCGCGGCGGTGCCTTCTATTCTGAGGTGGCGGTCGAATTGATCCGT
GCCATTCACAATAACAGCGGCAAGGTGCTGGTGGTGAATACTCGCAATAACGGTGCCATTCAGGGCTTGCCCGATGATGC
GGTGATTGAAACCAACTGTGTGATCGATGCCCAGGGGGCGCATCCGCTGAGTTTCGGCCCGCTGCCACTGGCCATGAACG
GGCTGACTCAACAGGTTAAAGATTTTGAACGCCTGACCATAGAGGCGGCGGTGCATGGCGATCGTCAGAGTGCGCTGTTG
GCGCTGGTGGTGAACCCGCTGATTGGCGGTGTCGGCATTGCGCAGCCCTTGCTCGATGAGGTACTGAGCCTGAACCAGGC
CTATCTGCCGCAGTTTAATTAA

Upstream 100 bases:

>100_bases
CTGGTGCACGCGCAGGATCATTTGATGAATGCAATGCTGATCCAGGATCTGGCTACTGACATGATCGAACTTTATCGTCG
TTTACCCCAGGGGGCAGGCA

Downstream 100 bases:

>100_bases
GTCGATATTCCATAATAACAATCACGACGGCCGGCTTTGCCGGGCAGGGGGGATGATGGCGGGTTTAAATAGCATTCTGG
AACGTTACGTGTTGCCGACG

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MTKITVIGGGSSYTPELVEGLIAHYQDVPLTELALVDVESGREKVGIIAELTKRMLKRNGLEQVVVSVHFTLEPAIRGAS
FVLTQLRVGQLAARAADERLGLKYQRLGQETTGVGGFAKALRTIPVMLEVARVVEAVAPDAWIINFTNPAGIVTEAVSRY
SKAKIIGLCNVPITMHHMIADMLKAPHDQVDLRFAGLNHMVWVHQVTQSGKDVTAKVLEMLSNGETLSMNNIKDLPWPPA
FLQALGAIPCPYHRYFYQTAGMLEEELEAAAAQGTRAEQVMKVEAELFALYADPTLDKKPEQLSFRGGAFYSEVAVELIR
AIHNNSGKVLVVNTRNNGAIQGLPDDAVIETNCVIDAQGAHPLSFGPLPLAMNGLTQQVKDFERLTIEAAVHGDRQSALL
ALVVNPLIGGVGIAQPLLDEVLSLNQAYLPQFN

Sequences:

>Translated_433_residues
MTKITVIGGGSSYTPELVEGLIAHYQDVPLTELALVDVESGREKVGIIAELTKRMLKRNGLEQVVVSVHFTLEPAIRGAS
FVLTQLRVGQLAARAADERLGLKYQRLGQETTGVGGFAKALRTIPVMLEVARVVEAVAPDAWIINFTNPAGIVTEAVSRY
SKAKIIGLCNVPITMHHMIADMLKAPHDQVDLRFAGLNHMVWVHQVTQSGKDVTAKVLEMLSNGETLSMNNIKDLPWPPA
FLQALGAIPCPYHRYFYQTAGMLEEELEAAAAQGTRAEQVMKVEAELFALYADPTLDKKPEQLSFRGGAFYSEVAVELIR
AIHNNSGKVLVVNTRNNGAIQGLPDDAVIETNCVIDAQGAHPLSFGPLPLAMNGLTQQVKDFERLTIEAAVHGDRQSALL
ALVVNPLIGGVGIAQPLLDEVLSLNQAYLPQFN
>Mature_432_residues
TKITVIGGGSSYTPELVEGLIAHYQDVPLTELALVDVESGREKVGIIAELTKRMLKRNGLEQVVVSVHFTLEPAIRGASF
VLTQLRVGQLAARAADERLGLKYQRLGQETTGVGGFAKALRTIPVMLEVARVVEAVAPDAWIINFTNPAGIVTEAVSRYS
KAKIIGLCNVPITMHHMIADMLKAPHDQVDLRFAGLNHMVWVHQVTQSGKDVTAKVLEMLSNGETLSMNNIKDLPWPPAF
LQALGAIPCPYHRYFYQTAGMLEEELEAAAAQGTRAEQVMKVEAELFALYADPTLDKKPEQLSFRGGAFYSEVAVELIRA
IHNNSGKVLVVNTRNNGAIQGLPDDAVIETNCVIDAQGAHPLSFGPLPLAMNGLTQQVKDFERLTIEAAVHGDRQSALLA
LVVNPLIGGVGIAQPLLDEVLSLNQAYLPQFN

Specific function: Hydrolyzes phospho-beta-glucosides (Probable) [H]

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=438, Percent_Identity=42.2374429223744, Blast_Score=330, Evalue=8e-92,
Organism=Escherichia coli, GI1790560, Length=463, Percent_Identity=25.0539956803456, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 46979; Mature: 46848

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS01324 GLYCOSYL_HYDROL_F4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKITVIGGGSSYTPELVEGLIAHYQDVPLTELALVDVESGREKVGIIAELTKRMLKRNG
CCEEEEEECCCCCCHHHHHHHHHHHCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHCC
LEQVVVSVHFTLEPAIRGASFVLTQLRVGQLAARAADERLGLKYQRLGQETTGVGGFAKA
HHEEEEEEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHH
LRTIPVMLEVARVVEAVAPDAWIINFTNPAGIVTEAVSRYSKAKIIGLCNVPITMHHMIA
HHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCEEEEEECCCHHHHHHHH
DMLKAPHDQVDLRFAGLNHMVWVHQVTQSGKDVTAKVLEMLSNGETLSMNNIKDLPWPPA
HHHHCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCHH
FLQALGAIPCPYHRYFYQTAGMLEEELEAAAAQGTRAEQVMKVEAELFALYADPTLDKKP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEECCCCCCCC
EQLSFRGGAFYSEVAVELIRAIHNNSGKVLVVNTRNNGAIQGLPDDAVIETNCVIDAQGA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEECEEEECCCC
HPLSFGPLPLAMNGLTQQVKDFERLTIEAAVHGDRQSALLALVVNPLIGGVGIAQPLLDE
CCCCCCCHHHHHHHHHHHHHHHHHHEEEEHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
VLSLNQAYLPQFN
HHHCCHHCCCCCC
>Mature Secondary Structure 
TKITVIGGGSSYTPELVEGLIAHYQDVPLTELALVDVESGREKVGIIAELTKRMLKRNG
CEEEEEECCCCCCHHHHHHHHHHHCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHCC
LEQVVVSVHFTLEPAIRGASFVLTQLRVGQLAARAADERLGLKYQRLGQETTGVGGFAKA
HHEEEEEEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHH
LRTIPVMLEVARVVEAVAPDAWIINFTNPAGIVTEAVSRYSKAKIIGLCNVPITMHHMIA
HHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCEEEEEECCCHHHHHHHH
DMLKAPHDQVDLRFAGLNHMVWVHQVTQSGKDVTAKVLEMLSNGETLSMNNIKDLPWPPA
HHHHCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCHH
FLQALGAIPCPYHRYFYQTAGMLEEELEAAAAQGTRAEQVMKVEAELFALYADPTLDKKP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEECCCCCCCC
EQLSFRGGAFYSEVAVELIRAIHNNSGKVLVVNTRNNGAIQGLPDDAVIETNCVIDAQGA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEECEEEECCCC
HPLSFGPLPLAMNGLTQQVKDFERLTIEAAVHGDRQSALLALVVNPLIGGVGIAQPLLDE
CCCCCCCHHHHHHHHHHHHHHHHHHEEEEHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
VLSLNQAYLPQFN
HHHCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 9384377; 8969509 [H]