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The map label for this gene is rhtC [H]

Identifier: 157370056

GI number: 157370056

Start: 1998612

End: 1999229

Strand: Reverse

Name: rhtC [H]

Synonym: Spro_1814

Alternate gene names: 157370056

Gene position: 1999229-1998612 (Counterclockwise)

Preceding gene: 157370058

Following gene: 157370055

Centisome position: 36.69

GC content: 55.18

Gene sequence:

>618_bases
ATGACCGAACTCATCGCCGTCGTCACCATTACCTTACTCGCTGTCATCAGTCCGGGGCCAGATTTTGCCATGGTGTCACG
CAACAGCCTGCTGCTTTCTCGTCGTGCCGGAGTGCTAACCGCCTGCGGTATTGGCGGCGGTGTTCTTATCCACGTCAGCT
ACACCCTGATCGGGGTCGGCGTATTGATCCAGCAATCGCTGTGGTTGTTCACAGTGTTGAAAGCAATCGGTGCCGCCTAC
CTGATTTACCTCGGCGTCAGCATGCTGCGTAACGCCGGTGCAAGTGCAGCCGCCTCTTCAACCACACCGGCCGCCGTTAG
CGATTTCGCTGCCCTGAAAACCGGATTTTTAACTAACGTATTGAACCCCAAAACCACCATTTTTATCGTTAGCCTGTTTA
TGCAAGTGGTTAACCCGCAGACACCGCTCGGCGTGCAAATCGGTTATGGGTTATTCATTGCACTTGCCCATATCCTCTGG
TTCAGCGCCGTCGCACTGCTGTTTTCGGCACCGGGCATCAATGCACGTCTGCTGCGGCTGCGTAAAGGCATCGACAGAGC
GTTTGGTGGCTTACTGATCACCTTCGGGGCGCTGCTGGCCATCGCCGGGATAAAATAA

Upstream 100 bases:

>100_bases
TGAGTTTTTCTCACCGATATCGTCAGTTTTCATCGTTTGTCACCGTCGAACATTCCTTTTATAAATCAGACACTCTCTTC
TGATTTTTTATAGGATTACT

Downstream 100 bases:

>100_bases
AGCCGTGAGGATAAGTTCAGTATTCACTTCTATGCTTAGGGGGGCATATCGTTCAATCACCAAAACGGAGAGTGGAACAT
GGCGAAAATATTGGTTCTTT

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTELIAVVTITLLAVISPGPDFAMVSRNSLLLSRRAGVLTACGIGGGVLIHVSYTLIGVGVLIQQSLWLFTVLKAIGAAY
LIYLGVSMLRNAGASAAASSTTPAAVSDFAALKTGFLTNVLNPKTTIFIVSLFMQVVNPQTPLGVQIGYGLFIALAHILW
FSAVALLFSAPGINARLLRLRKGIDRAFGGLLITFGALLAIAGIK

Sequences:

>Translated_205_residues
MTELIAVVTITLLAVISPGPDFAMVSRNSLLLSRRAGVLTACGIGGGVLIHVSYTLIGVGVLIQQSLWLFTVLKAIGAAY
LIYLGVSMLRNAGASAAASSTTPAAVSDFAALKTGFLTNVLNPKTTIFIVSLFMQVVNPQTPLGVQIGYGLFIALAHILW
FSAVALLFSAPGINARLLRLRKGIDRAFGGLLITFGALLAIAGIK
>Mature_204_residues
TELIAVVTITLLAVISPGPDFAMVSRNSLLLSRRAGVLTACGIGGGVLIHVSYTLIGVGVLIQQSLWLFTVLKAIGAAYL
IYLGVSMLRNAGASAAASSTTPAAVSDFAALKTGFLTNVLNPKTTIFIVSLFMQVVNPQTPLGVQIGYGLFIALAHILWF
SAVALLFSAPGINARLLRLRKGIDRAFGGLLITFGALLAIAGIK

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=204, Percent_Identity=34.3137254901961, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI1786522, Length=188, Percent_Identity=27.1276595744681, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI48994979, Length=195, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788099, Length=178, Percent_Identity=29.7752808988764, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21355; Mature: 21224

Theoretical pI: Translated: 11.03; Mature: 11.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELIAVVTITLLAVISPGPDFAMVSRNSLLLSRRAGVLTACGIGGGVLIHVSYTLIGVG
CCHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCCCEEEECCCCCCCEEEHHHHHHHHH
VLIQQSLWLFTVLKAIGAAYLIYLGVSMLRNAGASAAASSTTPAAVSDFAALKTGFLTNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
LNPKTTIFIVSLFMQVVNPQTPLGVQIGYGLFIALAHILWFSAVALLFSAPGINARLLRL
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RKGIDRAFGGLLITFGALLAIAGIK
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TELIAVVTITLLAVISPGPDFAMVSRNSLLLSRRAGVLTACGIGGGVLIHVSYTLIGVG
CHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCCCEEEECCCCCCCEEEHHHHHHHHH
VLIQQSLWLFTVLKAIGAAYLIYLGVSMLRNAGASAAASSTTPAAVSDFAALKTGFLTNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
LNPKTTIFIVSLFMQVVNPQTPLGVQIGYGLFIALAHILWFSAVALLFSAPGINARLLRL
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RKGIDRAFGGLLITFGALLAIAGIK
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]