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The map label for this gene is wrbA

Identifier: 157370055

GI number: 157370055

Start: 1997934

End: 1998533

Strand: Reverse

Name: wrbA

Synonym: Spro_1813

Alternate gene names: 157370055

Gene position: 1998533-1997934 (Counterclockwise)

Preceding gene: 157370056

Following gene: 157370054

Centisome position: 36.68

GC content: 59.83

Gene sequence:

>600_bases
ATGGCGAAAATATTGGTTCTTTATTACTCAATGTACGGACATATTGAAACCCTGGCGGAGGCGGTAGCGGAAGGCGCTCG
CCGGGTCAGTGGCGTTGAAGTGACCCTGAAACGGGTGCCGGAAACCATACCGGCAGAGGCCTTTGCCAAAGCCGGCGGTA
AACAAGACCAAAAAGCACCGGTGGCCAGCCCACAGGAGTTGGCCGATTACGATGGCATTATCTTCGGCACGCCAACCCGC
TTTGGCAACATGGCCGGGCAAATGCGCACCTTCCTCGATCAAACCGGCGGCCTGTGGGCCTCGGGTGCGCTGTACGGCAA
AGTGGGCAGCGTCTTCTCCTCCACCGGTACCGGCGGCGGGCAGGAACATACCATTACCTCCACCTGGACCACCCTGGCGC
ACCATGGCTTTATTATTGTGCCGATCGGTTACGCCACCCCTGAGCTGTTTGACGTCTCGCATGTGCGCGGCGGTACGCCT
TATGGCGCAACCACCATCGCCGGGGGGGACGGCTCACGCCAGCCGAGCCAGGAAGAGCTGACCATTGCCCGCTACCAGGG
CGAACACGTGGCGAAAATCACCGCCAAGCTGAAAAGTTAA

Upstream 100 bases:

>100_bases
GGCCATCGCCGGGATAAAATAAAGCCGTGAGGATAAGTTCAGTATTCACTTCTATGCTTAGGGGGGCATATCGTTCAATC
ACCAAAACGGAGAGTGGAAC

Downstream 100 bases:

>100_bases
GCGATAACCTTCTGTTACCTGCACTGCGGGGCCGTTGATTCCTTCGGCCCCATCTTGTTGCCAACCCGCAGCAAGGTTAA
AATGCCGCTCAGCCTGCCAT

Product: TrpR binding protein WrbA

Products: NA

Alternate protein names: Trp repressor-binding protein

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MAKILVLYYSMYGHIETLAEAVAEGARRVSGVEVTLKRVPETIPAEAFAKAGGKQDQKAPVASPQELADYDGIIFGTPTR
FGNMAGQMRTFLDQTGGLWASGALYGKVGSVFSSTGTGGGQEHTITSTWTTLAHHGFIIVPIGYATPELFDVSHVRGGTP
YGATTIAGGDGSRQPSQEELTIARYQGEHVAKITAKLKS

Sequences:

>Translated_199_residues
MAKILVLYYSMYGHIETLAEAVAEGARRVSGVEVTLKRVPETIPAEAFAKAGGKQDQKAPVASPQELADYDGIIFGTPTR
FGNMAGQMRTFLDQTGGLWASGALYGKVGSVFSSTGTGGGQEHTITSTWTTLAHHGFIIVPIGYATPELFDVSHVRGGTP
YGATTIAGGDGSRQPSQEELTIARYQGEHVAKITAKLKS
>Mature_198_residues
AKILVLYYSMYGHIETLAEAVAEGARRVSGVEVTLKRVPETIPAEAFAKAGGKQDQKAPVASPQELADYDGIIFGTPTRF
GNMAGQMRTFLDQTGGLWASGALYGKVGSVFSSTGTGGGQEHTITSTWTTLAHHGFIIVPIGYATPELFDVSHVRGGTPY
GATTIAGGDGSRQPSQEELTIARYQGEHVAKITAKLKS

Specific function: Seems to enhance the formation and/or stability of noncovalent complexes between the trp repressor protein and operator-bearing DNA

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain

Homologues:

Organism=Escherichia coli, GI1787239, Length=198, Percent_Identity=82.3232323232323, Blast_Score=335, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6320235, Length=199, Percent_Identity=45.2261306532663, Blast_Score=174, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319849, Length=201, Percent_Identity=45.771144278607, Blast_Score=171, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6319526, Length=202, Percent_Identity=37.1287128712871, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WRBA_SERP5 (A8GCS6)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478044.1
- ProteinModelPortal:   A8GCS6
- SMR:   A8GCS6
- STRING:   A8GCS6
- GeneID:   5605314
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_1813
- eggNOG:   COG0655
- HOGENOM:   HBG686708
- OMA:   TITSFHT
- ProtClustDB:   PRK03767
- BioCyc:   SPRO399741:SPRO_1813-MONOMER
- HAMAP:   MF_01017
- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025
- TIGRFAMs:   TIGR01755

Pfam domain/function: PF03358 FMN_red

EC number: NA

Molecular weight: Translated: 21034; Mature: 20903

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILVLYYSMYGHIETLAEAVAEGARRVSGVEVTLKRVPETIPAEAFAKAGGKQDQKAP
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCHHHHHHCCCCCCCCCC
VASPQELADYDGIIFGTPTRFGNMAGQMRTFLDQTGGLWASGALYGKVGSVFSSTGTGGG
CCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCC
QEHTITSTWTTLAHHGFIIVPIGYATPELFDVSHVRGGTPYGATTIAGGDGSRQPSQEEL
CCCEEHHHHHHHHHCCEEEEECCCCCCCCEEHHHCCCCCCCCCEEEECCCCCCCCCHHHE
TIARYQGEHVAKITAKLKS
EEEEECCCHHHHHHHHHCC
>Mature Secondary Structure 
AKILVLYYSMYGHIETLAEAVAEGARRVSGVEVTLKRVPETIPAEAFAKAGGKQDQKAP
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCHHHHHHCCCCCCCCCC
VASPQELADYDGIIFGTPTRFGNMAGQMRTFLDQTGGLWASGALYGKVGSVFSSTGTGGG
CCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCC
QEHTITSTWTTLAHHGFIIVPIGYATPELFDVSHVRGGTPYGATTIAGGDGSRQPSQEEL
CCCEEHHHHHHHHHCCEEEEECCCCCCCCEEHHHCCCCCCCCCEEEECCCCCCCCCHHHE
TIARYQGEHVAKITAKLKS
EEEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA