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The map label for this gene is uup [H]

Identifier: 157369987

GI number: 157369987

Start: 1922186

End: 1924090

Strand: Direct

Name: uup [H]

Synonym: Spro_1744

Alternate gene names: 157369987

Gene position: 1922186-1924090 (Clockwise)

Preceding gene: 157369986

Following gene: 157369988

Centisome position: 35.28

GC content: 55.64

Gene sequence:

>1905_bases
ATGTCGTTAATTAGCATGTCCGGTGCCTGGCTGTCCTTCAGCGATGCACCACTTTTAGACAACACCGAAATTCATATTGA
AGACAACGAACGCGTTTGTCTGGTTGGGCGCAATGGCGCCGGTAAATCCACGCTGTTGAAGATCCTCGGCAAAGAAATTC
CATTGGATGATGGCCGGGTGATTTACGAGCAGGATCTTATTGTGGCGCGCCTGCAACAGGATCCCCCGCGCAATATCGGC
GGTACGGTGTTTGATTTCGTGGCCGAAGGCGTCGCCGAGCAGGCAGAACACCTGAAAGCCTACCACGCGATTTCGCACCT
GGTGGAAACCGACCCAAGCGAAAGAAACCTGACGCGCATGGCGCAGATTATGGAGATCCTCGATCATCAGGGCCTGTGGC
AGCTCGATAGCCGCATCAGCGAAGTGCTGCTGCAGTTGGGCCTGAATGGGGATGCGGAACTTTCCTCGCTCTCCGGCGGC
TGGCTGCGTAAAGCGGCACTGGGCCGAGCGCTGGTAAGTTCTCCGCGCGTACTGTTGCTCGACGAACCGACCAACCACCT
GGATATTTCAACCATCGATTGGCTGGAAGGCTTCCTGAAAGAGTTCCAGGGCAGCATCGTGTTTATTTCCCACGACCGTT
CCTTTATCCGTAATATGGCGACGCGCATTGTCGATCTCGATCGCGGCAAGCTGGTGTCCTGGCCGGGCAACTACGATTTA
TACCTGCTGAGCAAAGAAGAAGCGCTGCGGGTGGAAGAGCTGCAAAATGCTGAATTTGACCGCAAGCTGGCGCAGGAAGA
AGTGTGGATCCGTCAGGGCATCAAGGCGCGTCGTACCCGTAACGAAGGCCGCGTTCGTGCGCTGAAGGCGTTGCGTAACG
AGCGTTCAGAACGCCGAGAAGTGATGGGCACCGCCAAAATGCAGGTGGAAGAAGCGGTACGCTCCGGCAAGATCGTGTTT
GAGATGGAAGACGTTAACTATCAGGTTGGCGGCAAAGTGTTGGTACGTAATTTCTCCGCCCAGGTGCAGCGTGGCGACAA
AATTGCGTTGGTTGGTCCGAACGGTTGCGGCAAGACTACGCTGCTGAAACTGATGCTCAGCCAGTTGAAAGCCGACAGCG
GCCGTGTGCACTGCGGGACCAAGCTGGAAGTGGCCTACTTCGACCAGCACCGTGCGGATCTGGATCCGGAGCGCACGGTC
ATGGACAACCTGGCGGAAGGTAAGCAGGAAGTATTGGTCAACGGCCGTTCACGCCACGTATTGGGTTATCTGCAGGACTT
CCTGTTCCACCCTAAACGGGCGATGACGCCGGTGAAAGCCTTGTCGGGCGGTGAGCGTAACCGTCTGTTGCTGGCCAAAC
TGTTCCTGAAGCCTAGTAACTTATTGATCCTCGATGAACCTACCAACGACCTGGATGTTGAAACGCTGGAGTTGCTGGAA
GAGCTGATCGACGGCTACCAGGGCACCGTGATGTTGGTCAGCCACGATCGTCAGTTCGTTGATAACTCGGTGACCGAATG
CTGGATCTTTGAAGGCAACGGTGAGATCAGCACCTTCGTTGGCGGTTATTACGACGCGCATCATCAACGCGCGACGGCTA
AACCGATCCGCCAGGTTACGGCTGAACAGAACAAGCCCGTAGCAGAAAAAAAGGCTGAACAGCCAAAGAAAACAGCGGCT
AAACTGAGCTATAACCTGCTACGTGAGCTGGAGCAGTTGCCGCAACGCCTTGAACAACTGGAAGCGGAAATTACTGCGCT
GCAGGCACAAATGAGCGATGCTGATTTCTTCACGCGTCCTCACAGCGAAACGCAACAGGTGCTGACGGCGCTGGCTACGG
CCGAAGGGGCACTGGAAGAGGCGTTCGCCCGTTGGGAAGAGTTGGAAGCGATGAAAAACGGCTAA

Upstream 100 bases:

>100_bases
AAGAAATTACCGCCCAGACGCAGTCGCAGGACTTTGCCCGTAACCGTCAAATTCATAACTGCTGGCTGCTTACCCATGCC
GGCGAAGGAAAATAATTACT

Downstream 100 bases:

>100_bases
CCGTTGAGAATACCGCCCGCGCGCTGCTGCGGGCGGTATTGCCGTACCGGTGAGCAACGTTGTTAAGGAGGAATATGGTG
TGTTCCCACGAGAATCACGA

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MSLISMSGAWLSFSDAPLLDNTEIHIEDNERVCLVGRNGAGKSTLLKILGKEIPLDDGRVIYEQDLIVARLQQDPPRNIG
GTVFDFVAEGVAEQAEHLKAYHAISHLVETDPSERNLTRMAQIMEILDHQGLWQLDSRISEVLLQLGLNGDAELSSLSGG
WLRKAALGRALVSSPRVLLLDEPTNHLDISTIDWLEGFLKEFQGSIVFISHDRSFIRNMATRIVDLDRGKLVSWPGNYDL
YLLSKEEALRVEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKALRNERSERREVMGTAKMQVEEAVRSGKIVF
EMEDVNYQVGGKVLVRNFSAQVQRGDKIALVGPNGCGKTTLLKLMLSQLKADSGRVHCGTKLEVAYFDQHRADLDPERTV
MDNLAEGKQEVLVNGRSRHVLGYLQDFLFHPKRAMTPVKALSGGERNRLLLAKLFLKPSNLLILDEPTNDLDVETLELLE
ELIDGYQGTVMLVSHDRQFVDNSVTECWIFEGNGEISTFVGGYYDAHHQRATAKPIRQVTAEQNKPVAEKKAEQPKKTAA
KLSYNLLRELEQLPQRLEQLEAEITALQAQMSDADFFTRPHSETQQVLTALATAEGALEEAFARWEELEAMKNG

Sequences:

>Translated_634_residues
MSLISMSGAWLSFSDAPLLDNTEIHIEDNERVCLVGRNGAGKSTLLKILGKEIPLDDGRVIYEQDLIVARLQQDPPRNIG
GTVFDFVAEGVAEQAEHLKAYHAISHLVETDPSERNLTRMAQIMEILDHQGLWQLDSRISEVLLQLGLNGDAELSSLSGG
WLRKAALGRALVSSPRVLLLDEPTNHLDISTIDWLEGFLKEFQGSIVFISHDRSFIRNMATRIVDLDRGKLVSWPGNYDL
YLLSKEEALRVEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKALRNERSERREVMGTAKMQVEEAVRSGKIVF
EMEDVNYQVGGKVLVRNFSAQVQRGDKIALVGPNGCGKTTLLKLMLSQLKADSGRVHCGTKLEVAYFDQHRADLDPERTV
MDNLAEGKQEVLVNGRSRHVLGYLQDFLFHPKRAMTPVKALSGGERNRLLLAKLFLKPSNLLILDEPTNDLDVETLELLE
ELIDGYQGTVMLVSHDRQFVDNSVTECWIFEGNGEISTFVGGYYDAHHQRATAKPIRQVTAEQNKPVAEKKAEQPKKTAA
KLSYNLLRELEQLPQRLEQLEAEITALQAQMSDADFFTRPHSETQQVLTALATAEGALEEAFARWEELEAMKNG
>Mature_633_residues
SLISMSGAWLSFSDAPLLDNTEIHIEDNERVCLVGRNGAGKSTLLKILGKEIPLDDGRVIYEQDLIVARLQQDPPRNIGG
TVFDFVAEGVAEQAEHLKAYHAISHLVETDPSERNLTRMAQIMEILDHQGLWQLDSRISEVLLQLGLNGDAELSSLSGGW
LRKAALGRALVSSPRVLLLDEPTNHLDISTIDWLEGFLKEFQGSIVFISHDRSFIRNMATRIVDLDRGKLVSWPGNYDLY
LLSKEEALRVEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKALRNERSERREVMGTAKMQVEEAVRSGKIVFE
MEDVNYQVGGKVLVRNFSAQVQRGDKIALVGPNGCGKTTLLKLMLSQLKADSGRVHCGTKLEVAYFDQHRADLDPERTVM
DNLAEGKQEVLVNGRSRHVLGYLQDFLFHPKRAMTPVKALSGGERNRLLLAKLFLKPSNLLILDEPTNDLDVETLELLEE
LIDGYQGTVMLVSHDRQFVDNSVTECWIFEGNGEISTFVGGYYDAHHQRATAKPIRQVTAEQNKPVAEKKAEQPKKTAAK
LSYNLLRELEQLPQRLEQLEAEITALQAQMSDADFFTRPHSETQQVLTALATAEGALEEAFARWEELEAMKNG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=527, Percent_Identity=30.9297912713473, Blast_Score=209, Evalue=9e-54,
Organism=Homo sapiens, GI27881506, Length=518, Percent_Identity=30.5019305019305, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI10947137, Length=518, Percent_Identity=30.5019305019305, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI10947135, Length=546, Percent_Identity=28.021978021978, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI69354671, Length=546, Percent_Identity=28.021978021978, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI42741659, Length=218, Percent_Identity=25.2293577981651, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1787182, Length=634, Percent_Identity=78.7066246056782, Blast_Score=989, Evalue=0.0,
Organism=Escherichia coli, GI2367384, Length=520, Percent_Identity=33.2692307692308, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1787041, Length=534, Percent_Identity=32.7715355805243, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1789751, Length=638, Percent_Identity=28.0564263322884, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1788506, Length=536, Percent_Identity=25.7462686567164, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787712, Length=245, Percent_Identity=27.3469387755102, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789891, Length=249, Percent_Identity=26.1044176706827, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790467, Length=228, Percent_Identity=28.5087719298246, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788225, Length=229, Percent_Identity=26.2008733624454, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786319, Length=157, Percent_Identity=33.7579617834395, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787105, Length=224, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=29.4117647058824, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=541, Percent_Identity=28.2809611829945, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17555318, Length=521, Percent_Identity=28.2149712092131, Blast_Score=195, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17553372, Length=553, Percent_Identity=31.1030741410488, Blast_Score=186, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6321121, Length=534, Percent_Identity=30.1498127340824, Blast_Score=203, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6320874, Length=527, Percent_Identity=29.4117647058824, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6323278, Length=383, Percent_Identity=25.3263707571802, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6325030, Length=388, Percent_Identity=26.0309278350515, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324314, Length=385, Percent_Identity=25.4545454545455, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24666836, Length=532, Percent_Identity=30.6390977443609, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24642252, Length=539, Percent_Identity=28.2003710575139, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI18859989, Length=539, Percent_Identity=28.2003710575139, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24641342, Length=547, Percent_Identity=28.7020109689214, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI116007184, Length=175, Percent_Identity=29.7142857142857, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221500365, Length=177, Percent_Identity=30.5084745762712, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363262, Length=217, Percent_Identity=24.4239631336406, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24653245, Length=217, Percent_Identity=24.4239631336406, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17136662, Length=197, Percent_Identity=24.8730964467005, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71323; Mature: 71192

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLISMSGAWLSFSDAPLLDNTEIHIEDNERVCLVGRNGAGKSTLLKILGKEIPLDDGRV
CCEEECCCCEEECCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCE
IYEQDLIVARLQQDPPRNIGGTVFDFVAEGVAEQAEHLKAYHAISHLVETDPSERNLTRM
EEECCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AQIMEILDHQGLWQLDSRISEVLLQLGLNGDAELSSLSGGWLRKAALGRALVSSPRVLLL
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEE
DEPTNHLDISTIDWLEGFLKEFQGSIVFISHDRSFIRNMATRIVDLDRGKLVSWPGNYDL
ECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHEECCCCCEEECCCCCEE
YLLSKEEALRVEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKALRNERSERRE
EEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
VMGTAKMQVEEAVRSGKIVFEMEDVNYQVGGKVLVRNFSAQVQRGDKIALVGPNGCGKTT
HHHHHHHHHHHHHHCCCEEEEEECCCEECCCEEEEEHHHHHHCCCCEEEEECCCCCCHHH
LLKLMLSQLKADSGRVHCGTKLEVAYFDQHRADLDPERTVMDNLAEGKQEVLVNGRSRHV
HHHHHHHHHCCCCCCEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHCCCCCHHH
LGYLQDFLFHPKRAMTPVKALSGGERNRLLLAKLFLKPSNLLILDEPTNDLDVETLELLE
HHHHHHHHHCCHHHCCHHHHHCCCCCCCEEEEHHHCCCCCEEEEECCCCCCCHHHHHHHH
ELIDGYQGTVMLVSHDRQFVDNSVTECWIFEGNGEISTFVGGYYDAHHQRATAKPIRQVT
HHHCCCCCEEEEEECCHHHHCCCCCEEEEEECCCCEEEHHCCHHHHHHHHHHHHHHHHHH
AEQNKPVAEKKAEQPKKTAAKLSYNLLRELEQLPQRLEQLEAEITALQAQMSDADFFTRP
HHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
HSETQQVLTALATAEGALEEAFARWEELEAMKNG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLISMSGAWLSFSDAPLLDNTEIHIEDNERVCLVGRNGAGKSTLLKILGKEIPLDDGRV
CEEECCCCEEECCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCE
IYEQDLIVARLQQDPPRNIGGTVFDFVAEGVAEQAEHLKAYHAISHLVETDPSERNLTRM
EEECCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AQIMEILDHQGLWQLDSRISEVLLQLGLNGDAELSSLSGGWLRKAALGRALVSSPRVLLL
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEE
DEPTNHLDISTIDWLEGFLKEFQGSIVFISHDRSFIRNMATRIVDLDRGKLVSWPGNYDL
ECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHEECCCCCEEECCCCCEE
YLLSKEEALRVEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKALRNERSERRE
EEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
VMGTAKMQVEEAVRSGKIVFEMEDVNYQVGGKVLVRNFSAQVQRGDKIALVGPNGCGKTT
HHHHHHHHHHHHHHCCCEEEEEECCCEECCCEEEEEHHHHHHCCCCEEEEECCCCCCHHH
LLKLMLSQLKADSGRVHCGTKLEVAYFDQHRADLDPERTVMDNLAEGKQEVLVNGRSRHV
HHHHHHHHHCCCCCCEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHCCCCCHHH
LGYLQDFLFHPKRAMTPVKALSGGERNRLLLAKLFLKPSNLLILDEPTNDLDVETLELLE
HHHHHHHHHCCHHHCCHHHHHCCCCCCCEEEEHHHCCCCCEEEEECCCCCCCHHHHHHHH
ELIDGYQGTVMLVSHDRQFVDNSVTECWIFEGNGEISTFVGGYYDAHHQRATAKPIRQVT
HHHCCCCCEEEEEECCHHHHCCCCCEEEEEECCCCEEEHHCCHHHHHHHHHHHHHHHHHH
AEQNKPVAEKKAEQPKKTAAKLSYNLLRELEQLPQRLEQLEAEITALQAQMSDADFFTRP
HHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
HSETQQVLTALATAEGALEEAFARWEELEAMKNG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9139905; 7751275 [H]