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The map label for this gene is asnC

Identifier: 157369974

GI number: 157369974

Start: 1904655

End: 1906055

Strand: Reverse

Name: asnC

Synonym: Spro_1731

Alternate gene names: 157369974

Gene position: 1906055-1904655 (Counterclockwise)

Preceding gene: 157369975

Following gene: 157369973

Centisome position: 34.98

GC content: 53.82

Gene sequence:

>1401_bases
ATGAGCGTAGTGCCTGTAGTCGACGTACTGCAAGGCCGTGCTGCGGTTGACAGTGAAGTCACCGTACGCGGTTGGGTGCG
TACCCGGAGAGATTCTAAAGCTGGTATCTCCTTCCTGGCCGTCTATGACGGTTCCTGCTTTGATCCGTTACAGGCCGTCG
TTAATAATTCTCTGCCGAATTATCAGGATGAAGTGCTGCATCTGACCACGGGCTGTTCCATTGAAGTCACCGGCGTTGTG
GTGGCATCTCCGGGCGAAGGTCAGAGTTTCGAACTGCAGGCAACCGCGATTAAAGTGGTTGGCTGGGTTGACGATCCGGA
CACCTACCCGATGGCGGCCAAACGTCACAGCATCGAATACCTGCGCGAAGTGGCTCACCTGCGCCCACGCACCAATCTGA
TCGGTGCCGTTGCCCGCGTACGTCATACGCTGGCACAGGCCATTCACCGTTTCTATCACGAGAACGGCTTCTTCTGGGTT
TCCACCCCGCTGATCACCGCCTCCGATACCGAAGGTGCCGGTGAAATGTTCCGCGTTTCAACTCTGGATCTGGAAAATCT
GCCGCGTACCGATAAGGGTGCAGTCGATTTCAGCCAGGACTTTTTCGGCAAAGAAGCCTTCCTGACCGTTTCCGGCCAGT
TGAACGGCGAGACCTATGCCTGTGCGCTGTCGAAAATTTACACTTTCGGCCCCACTTTCCGCGCCGAGAACTCCAACACC
AGCCGCCACCTGGCGGAGTTTTGGATGATCGAACCGGAAGTGGCGTTTGCCGATCTCGAAGACATCGCCGAGTTGGCGGA
AAAAATGCTGAAGTATGTATTCCAGGCCGTATTGAACGAGCGTATGGATGACATGCAGTTCTTCGCCGAGCGCGTAGACA
AAGATGCTATCGATCGCCTGCAGCGTTTTGTTACTTCTGACTTTGCTCAGGTTGATTACACCGAAGCGGTGGAAATCCTG
ATCGCCTCAGGTCAGACTTTCGAAAACCCGGTTTCCTGGGGTATCGACCTGTCTTCCGAACATGAGCGTTATTTGGCCGA
GAAACACTTCAAAGCGCCGGTAGTAGTGAAAAACTACCCGAAAGACATCAAAGCTTTCTATATGCGTATGAACGATGACG
GTAAAACCGTTGCCGCAATGGACGTTCTGGCTCCGGGCATTGGTGAAATCATCGGCGGTGCTCAGCGTGAAGAACGTCTG
GACGTACTGGATCAGCGTCTGGAAGCCATGGGGCTGAATAAAGAAGACTACTGGTGGTATCGCGATCTTCGTCGTTACGG
CACCGTTCCTCATGCCGGTTTCGGTTTGGGCTTTGAGCGTTTAATCGCCTATGTCACCGGCGTTCAAAACGTGCGTGATG
TCATTCCGTTCCCGCGGACTCCACGTAATGCAACCTTTTAA

Upstream 100 bases:

>100_bases
TTTCTACTTGTGCTCTGCACCGCGGCAAGTAACATAGCAACATCCCCATATTCTTGGGTTATAAGCTATTTCTAAACCAA
ATTATTAAAGAGAGAAATCT

Downstream 100 bases:

>100_bases
TTAATCAGATAATACATTTTCTAATTAATTTAGTTACAAAACCAAGGCCAGCTTTGCTGGCCTTTCGCATTTTTTAATAT
TGACGCGCGTCACAAAGTTC

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSVVPVVDVLQGRAAVDSEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPLQAVVNNSLPNYQDEVLHLTTGCSIEVTGVV
VASPGEGQSFELQATAIKVVGWVDDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFYHENGFFWV
STPLITASDTEGAGEMFRVSTLDLENLPRTDKGAVDFSQDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMIEPEVAFADLEDIAELAEKMLKYVFQAVLNERMDDMQFFAERVDKDAIDRLQRFVTSDFAQVDYTEAVEIL
IASGQTFENPVSWGIDLSSEHERYLAEKHFKAPVVVKNYPKDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGAQREERL
DVLDQRLEAMGLNKEDYWWYRDLRRYGTVPHAGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNATF

Sequences:

>Translated_466_residues
MSVVPVVDVLQGRAAVDSEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPLQAVVNNSLPNYQDEVLHLTTGCSIEVTGVV
VASPGEGQSFELQATAIKVVGWVDDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFYHENGFFWV
STPLITASDTEGAGEMFRVSTLDLENLPRTDKGAVDFSQDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMIEPEVAFADLEDIAELAEKMLKYVFQAVLNERMDDMQFFAERVDKDAIDRLQRFVTSDFAQVDYTEAVEIL
IASGQTFENPVSWGIDLSSEHERYLAEKHFKAPVVVKNYPKDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGAQREERL
DVLDQRLEAMGLNKEDYWWYRDLRRYGTVPHAGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNATF
>Mature_465_residues
SVVPVVDVLQGRAAVDSEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPLQAVVNNSLPNYQDEVLHLTTGCSIEVTGVVV
ASPGEGQSFELQATAIKVVGWVDDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFYHENGFFWVS
TPLITASDTEGAGEMFRVSTLDLENLPRTDKGAVDFSQDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTS
RHLAEFWMIEPEVAFADLEDIAELAEKMLKYVFQAVLNERMDDMQFFAERVDKDAIDRLQRFVTSDFAQVDYTEAVEILI
ASGQTFENPVSWGIDLSSEHERYLAEKHFKAPVVVKNYPKDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGAQREERLD
VLDQRLEAMGLNKEDYWWYRDLRRYGTVPHAGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNATF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=463, Percent_Identity=43.6285097192225, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI4758762, Length=460, Percent_Identity=25.8695652173913, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI45439306, Length=347, Percent_Identity=30.835734870317, Blast_Score=124, Evalue=3e-28,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=86.2660944206009, Blast_Score=857, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=474, Percent_Identity=23.6286919831224, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789256, Length=339, Percent_Identity=22.4188790560472, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788173, Length=184, Percent_Identity=27.7173913043478, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71984122, Length=472, Percent_Identity=29.6610169491525, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17556372, Length=430, Percent_Identity=30, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17551876, Length=345, Percent_Identity=27.2463768115942, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319872, Length=471, Percent_Identity=36.0934182590234, Blast_Score=290, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6321807, Length=460, Percent_Identity=29.5652173913043, Blast_Score=190, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6323011, Length=501, Percent_Identity=24.9500998003992, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19922416, Length=463, Percent_Identity=35.85313174946, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI19921528, Length=475, Percent_Identity=27.5789473684211, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17136276, Length=346, Percent_Identity=27.7456647398844, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_SERP5 (A8GCJ5)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477963.1
- ProteinModelPortal:   A8GCJ5
- SMR:   A8GCJ5
- STRING:   A8GCJ5
- GeneID:   5604585
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_1731
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- BioCyc:   SPRO399741:SPRO_1731-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 52401; Mature: 52270

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVPVVDVLQGRAAVDSEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPLQAVVNNSLPN
CCCCCHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCC
YQDEVLHLTTGCSIEVTGVVVASPGEGQSFELQATAIKVVGWVDDPDTYPMAAKRHSIEY
CCCCEEEEECCCEEEEEEEEEECCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHH
LREVAHLRPRTNLIGAVARVRHTLAQAIHRFYHENGFFWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRTDKGAVDFSQDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
EECHHCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMIEPEVAFADLEDIAELAEKMLKYVFQAVLNERMDDMQFFAERVDKDAIDRL
HHHHHHHHEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
QRFVTSDFAQVDYTEAVEILIASGQTFENPVSWGIDLSSEHERYLAEKHFKAPVVVKNYP
HHHHHHHHHHCCHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGAQREERLDVLDQRLEAMGLNKEDYWWY
HHHEEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHAGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNATF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SVVPVVDVLQGRAAVDSEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPLQAVVNNSLPN
CCCCHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCC
YQDEVLHLTTGCSIEVTGVVVASPGEGQSFELQATAIKVVGWVDDPDTYPMAAKRHSIEY
CCCCEEEEECCCEEEEEEEEEECCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHH
LREVAHLRPRTNLIGAVARVRHTLAQAIHRFYHENGFFWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRTDKGAVDFSQDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
EECHHCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMIEPEVAFADLEDIAELAEKMLKYVFQAVLNERMDDMQFFAERVDKDAIDRL
HHHHHHHHEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
QRFVTSDFAQVDYTEAVEILIASGQTFENPVSWGIDLSSEHERYLAEKHFKAPVVVKNYP
HHHHHHHHHHCCHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRMNDDGKTVAAMDVLAPGIGEIIGGAQREERLDVLDQRLEAMGLNKEDYWWY
HHHEEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHH
RDLRRYGTVPHAGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNATF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA