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The map label for this gene is mukE [H]

Identifier: 157369967

GI number: 157369967

Start: 1893055

End: 1893783

Strand: Direct

Name: mukE [H]

Synonym: Spro_1724

Alternate gene names: 157369967

Gene position: 1893055-1893783 (Clockwise)

Preceding gene: 157369966

Following gene: 157369968

Centisome position: 34.74

GC content: 54.32

Gene sequence:

>729_bases
ATGTCATCGACAAATATTGAACAAATAATGCCAGTCAAGCTGGCCAAGGCATTGTCTAACGCGCTGTTCCCGGCGCTGGA
CAGCCAACTGCGTGCGGGTCGTCACATCGGTATCGATGAACTGGACAACCACGCCTTCTTAATGGATTTCCAGGATGAAC
TGGAAGAATTCTACACCCGCTACAGCGTAGAGCTGATCCGCGCGCCGGAAGGATTCTTCTATCTGCGTCCACGCTCTACC
ACGCTGATCCCGCGTTCGGTGCTGTCCGAGCTGGATATGATGGTGGGGAAAATCCTGTGCTATCTGTATCTCAGCCCGGA
ACGTCTGGCGCATGAGGGCATTTTCAGCCATCAGGAGCTGTACGACGAGCTGCTGAGCCTGGCGGACGAGAGCAAATTGC
TGAAGTTCGTTAATCAGCGTTCTACCGGCTCGGATCTCGATCGCCAGAAGCTGCATGAAAAAGTACGTACTTCACTGAAC
CGTCTGCGTCGTTTGGGCATGGTCTATTTCATGGGCAACGACAGCAGCAAGTTCCGTATTACCGAGGCGGTATTCCGCTT
TGGCGCCGATGTACGCAGCGGTGACGATCCGCGTGAAGCGCAGTTGCGTATGATCCGCGACGGCGAAGCAATGCCGGTTG
AAAACAGCCTGTTGCTGAATGATGAGAGCGATGCGGAAGACTCGCCGCTTGATACCACACCGGACAGTGCAGAGGATGAA
CAGGAATGA

Upstream 100 bases:

>100_bases
GTCGACCAGGCAGTGCGCCTTGGTGTGGCTGAAGCAGATTTTTCAGGGTTGCCGGCACAGTGGCAGGCAATCAATGATTA
CGGAGCCAAGGTCCAGGCCC

Downstream 100 bases:

>100_bases
TTGAACGCGGTAAATTTCGCTCGCTGACGTTGGTTAACTGGAACGGCTTCTTTGCCCGCACCTTTGATCTCGATGAGTTG
GTGACCACGCTGTCCGGCGG

Product: condesin subunit E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSSTNIEQIMPVKLAKALSNALFPALDSQLRAGRHIGIDELDNHAFLMDFQDELEEFYTRYSVELIRAPEGFFYLRPRST
TLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSHQELYDELLSLADESKLLKFVNQRSTGSDLDRQKLHEKVRTSLN
RLRRLGMVYFMGNDSSKFRITEAVFRFGADVRSGDDPREAQLRMIRDGEAMPVENSLLLNDESDAEDSPLDTTPDSAEDE
QE

Sequences:

>Translated_242_residues
MSSTNIEQIMPVKLAKALSNALFPALDSQLRAGRHIGIDELDNHAFLMDFQDELEEFYTRYSVELIRAPEGFFYLRPRST
TLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSHQELYDELLSLADESKLLKFVNQRSTGSDLDRQKLHEKVRTSLN
RLRRLGMVYFMGNDSSKFRITEAVFRFGADVRSGDDPREAQLRMIRDGEAMPVENSLLLNDESDAEDSPLDTTPDSAEDE
QE
>Mature_241_residues
SSTNIEQIMPVKLAKALSNALFPALDSQLRAGRHIGIDELDNHAFLMDFQDELEEFYTRYSVELIRAPEGFFYLRPRSTT
LIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSHQELYDELLSLADESKLLKFVNQRSTGSDLDRQKLHEKVRTSLNR
LRRLGMVYFMGNDSSKFRITEAVFRFGADVRSGDDPREAQLRMIRDGEAMPVENSLLLNDESDAEDSPLDTTPDSAEDEQ
E

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interactio

COG id: COG3095

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukE family [H]

Homologues:

Organism=Escherichia coli, GI226510932, Length=240, Percent_Identity=82.0833333333333, Blast_Score=407, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007385 [H]

Pfam domain/function: PF04288 MukE [H]

EC number: NA

Molecular weight: Translated: 27718; Mature: 27586

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTNIEQIMPVKLAKALSNALFPALDSQLRAGRHIGIDELDNHAFLMDFQDELEEFYTR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHH
YSVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSHQEL
HHHHEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHH
YDELLSLADESKLLKFVNQRSTGSDLDRQKLHEKVRTSLNRLRRLGMVYFMGNDSSKFRI
HHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHH
TEAVFRFGADVRSGDDPREAQLRMIRDGEAMPVENSLLLNDESDAEDSPLDTTPDSAEDE
HHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
QE
CC
>Mature Secondary Structure 
SSTNIEQIMPVKLAKALSNALFPALDSQLRAGRHIGIDELDNHAFLMDFQDELEEFYTR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHH
YSVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSHQEL
HHHHEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHH
YDELLSLADESKLLKFVNQRSTGSDLDRQKLHEKVRTSLNRLRRLGMVYFMGNDSSKFRI
HHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHH
TEAVFRFGADVRSGDDPREAQLRMIRDGEAMPVENSLLLNDESDAEDSPLDTTPDSAEDE
HHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
QE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]