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The map label for this gene is mukF

Identifier: 157369966

GI number: 157369966

Start: 1891752

End: 1893074

Strand: Direct

Name: mukF

Synonym: Spro_1723

Alternate gene names: 157369966

Gene position: 1891752-1893074 (Clockwise)

Preceding gene: 157369965

Following gene: 157369967

Centisome position: 34.72

GC content: 55.48

Gene sequence:

>1323_bases
ATGAGTGAATTTTCCCAGACAGTACCCGAACTGGTCGCCTGGGCACGGAAAAATGATTTCTCTATTTCGCTCCCTACGGA
GCGTCTCGCGTTTTTGCTTGCTATCGCCACTTTGAACGGCGAGCGGCTGGACGGCGAGATGAGCGAAGGTGAGCTGGTTG
ATGCATTTCGCCATGTCAGCAAGGGTTTCGAACAGACGCATGAAACGGTGGCCGTGCGCGCCAACAATGCGATTAACGAC
ATGGTGCGCCAGCGCCTGTTAAACCGTTTTATCAGCGAACTGGCGGACGGTAACGCGATTTACCGTCTGACGCCGCTGGG
CATCGGTATTACCGATTACTATATCCGTCAGCGCGAATTCTCCACGCTGCGTTTGTCGATGCAGTTGTCAATTGTGGCGC
AGGAGCTCAAACGCGCCGCCGACGCTGCCGATGAAGGCGGTGACGATTTCCACTGGCACCGCAACGTGTTTGCACCGCTG
AAATATTCGGTGGCGGAAATCTTCGACAGTATCGATTTGACCCAGCGAATTATGGATGAACAGCAGCAGGGCGTGAAGGA
CGACATCGCAGCGCTGCTGAACAAAGACTGGCGTGCGGCGATCTCCAGCTGTGAGATGCTGCTGTCCGAAACCTCGGGCA
CCCTGCGCGAACTGCAGGATACGCTGGAGGCGGCGGGCGATAAACTGCAGGCCAACCTGTTGCGAATTCAGGATGCCACA
CTGGGTGGCGCGGAACTGGGCTTTATCGACAAACTGGTGTTCGATCTGCAAAGCAAGCTCGACCGCATTATCAGTTGGGG
CCAGCAGGCGATTGACCTGTGGATTGGCTACGACCGCCACGTGCATAAATTTATCCGTACCGCGATCGACATGGACAAGA
ACCGGGTGTTCGCCCAGCGTTTGCGTCAGTCGGTGCAAAACTATTTCGACAACCCATGGACACTGACCCATGCCAATGCC
GACCGTCTGCTGGATATGCGAGACGAAGAACTGGCGCTGCGCAGCGAGGAAGTGACCGGGGAACTGCCGCCGGATCTGGA
GTTCGAAGAGTTCAGCGAAATCCGTGAGCAACTGGCGGCAATGATCGAACAGGCACTGAAGATTTATCAGGAACAACAGA
TGCCGCTCAATTTAGGGGCGGTAATGCGCGATTATCTGGCGCAATATCCGCGTGCTCGTCATTTCGATGTGGCACGTTTA
GTGGTCGACCAGGCAGTGCGCCTTGGTGTGGCTGAAGCAGATTTTTCAGGGTTGCCGGCACAGTGGCAGGCAATCAATGA
TTACGGAGCCAAGGTCCAGGCCCATGTCATCGACAAATATTGA

Upstream 100 bases:

>100_bases
TACTGGCGCTTGAACAGCACTATTGCCGGCAGGAGCCGTACGTGAGTTTGGGGCGCTATATTCACGTCATGGCGCATAAA
CCAAACCTGAAGGACGAACT

Downstream 100 bases:

>100_bases
ACAAATAATGCCAGTCAAGCTGGCCAAGGCATTGTCTAACGCGCTGTTCCCGGCGCTGGACAGCCAACTGCGTGCGGGTC
GTCACATCGGTATCGATGAA

Product: condesin subunit F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSEFSQTVPELVAWARKNDFSISLPTERLAFLLAIATLNGERLDGEMSEGELVDAFRHVSKGFEQTHETVAVRANNAIND
MVRQRLLNRFISELADGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAQELKRAADAADEGGDDFHWHRNVFAPL
KYSVAEIFDSIDLTQRIMDEQQQGVKDDIAALLNKDWRAAISSCEMLLSETSGTLRELQDTLEAAGDKLQANLLRIQDAT
LGGAELGFIDKLVFDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQNYFDNPWTLTHANA
DRLLDMRDEELALRSEEVTGELPPDLEFEEFSEIREQLAAMIEQALKIYQEQQMPLNLGAVMRDYLAQYPRARHFDVARL
VVDQAVRLGVAEADFSGLPAQWQAINDYGAKVQAHVIDKY

Sequences:

>Translated_440_residues
MSEFSQTVPELVAWARKNDFSISLPTERLAFLLAIATLNGERLDGEMSEGELVDAFRHVSKGFEQTHETVAVRANNAIND
MVRQRLLNRFISELADGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAQELKRAADAADEGGDDFHWHRNVFAPL
KYSVAEIFDSIDLTQRIMDEQQQGVKDDIAALLNKDWRAAISSCEMLLSETSGTLRELQDTLEAAGDKLQANLLRIQDAT
LGGAELGFIDKLVFDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQNYFDNPWTLTHANA
DRLLDMRDEELALRSEEVTGELPPDLEFEEFSEIREQLAAMIEQALKIYQEQQMPLNLGAVMRDYLAQYPRARHFDVARL
VVDQAVRLGVAEADFSGLPAQWQAINDYGAKVQAHVIDKY
>Mature_439_residues
SEFSQTVPELVAWARKNDFSISLPTERLAFLLAIATLNGERLDGEMSEGELVDAFRHVSKGFEQTHETVAVRANNAINDM
VRQRLLNRFISELADGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAQELKRAADAADEGGDDFHWHRNVFAPLK
YSVAEIFDSIDLTQRIMDEQQQGVKDDIAALLNKDWRAAISSCEMLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATL
GGAELGFIDKLVFDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQNYFDNPWTLTHANAD
RLLDMRDEELALRSEEVTGELPPDLEFEEFSEIREQLAAMIEQALKIYQEQQMPLNLGAVMRDYLAQYPRARHFDVARLV
VDQAVRLGVAEADFSGLPAQWQAINDYGAKVQAHVIDKY

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid

COG id: COG3006

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukF family

Homologues:

Organism=Escherichia coli, GI1787152, Length=440, Percent_Identity=86.8181818181818, Blast_Score=797, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MUKF_SERP5 (A8GCI7)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477955.1
- ProteinModelPortal:   A8GCI7
- SMR:   A8GCI7
- STRING:   A8GCI7
- GeneID:   5604491
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_1723
- eggNOG:   COG3006
- HOGENOM:   HBG296836
- OMA:   NRFSSEF
- ProtClustDB:   PRK05260
- BioCyc:   SPRO399741:SPRO_1723-MONOMER
- GO:   GO:0005737
- GO:   GO:0009295
- HAMAP:   MF_01803
- InterPro:   IPR005582
- PIRSF:   PIRSF018282

Pfam domain/function: PF03882 KicB

EC number: NA

Molecular weight: Translated: 50110; Mature: 49979

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFSQTVPELVAWARKNDFSISLPTERLAFLLAIATLNGERLDGEMSEGELVDAFRHVS
CCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
KGFEQTHETVAVRANNAINDMVRQRLLNRFISELADGNAIYRLTPLGIGITDYYIRQREF
HHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHH
STLRLSMQLSIVAQELKRAADAADEGGDDFHWHRNVFAPLKYSVAEIFDSIDLTQRIMDE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
QQQGVKDDIAALLNKDWRAAISSCEMLLSETSGTLRELQDTLEAAGDKLQANLLRIQDAT
HHCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHECCC
LGGAELGFIDKLVFDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHH
LRQSVQNYFDNPWTLTHANADRLLDMRDEELALRSEEVTGELPPDLEFEEFSEIREQLAA
HHHHHHHHCCCCCEEEECCHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
MIEQALKIYQEQQMPLNLGAVMRDYLAQYPRARHFDVARLVVDQAVRLGVAEADFSGLPA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCH
QWQAINDYGAKVQAHVIDKY
HHHHHHHHCCEEEEEECCCC
>Mature Secondary Structure 
SEFSQTVPELVAWARKNDFSISLPTERLAFLLAIATLNGERLDGEMSEGELVDAFRHVS
CHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
KGFEQTHETVAVRANNAINDMVRQRLLNRFISELADGNAIYRLTPLGIGITDYYIRQREF
HHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHH
STLRLSMQLSIVAQELKRAADAADEGGDDFHWHRNVFAPLKYSVAEIFDSIDLTQRIMDE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
QQQGVKDDIAALLNKDWRAAISSCEMLLSETSGTLRELQDTLEAAGDKLQANLLRIQDAT
HHCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHECCC
LGGAELGFIDKLVFDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHH
LRQSVQNYFDNPWTLTHANADRLLDMRDEELALRSEEVTGELPPDLEFEEFSEIREQLAA
HHHHHHHHCCCCCEEEECCHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
MIEQALKIYQEQQMPLNLGAVMRDYLAQYPRARHFDVARLVVDQAVRLGVAEADFSGLPA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCH
QWQAINDYGAKVQAHVIDKY
HHHHHHHHCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA