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The map label for this gene is dmsD [H]

Identifier: 157369933

GI number: 157369933

Start: 1853217

End: 1853834

Strand: Direct

Name: dmsD [H]

Synonym: Spro_1690

Alternate gene names: 157369933

Gene position: 1853217-1853834 (Clockwise)

Preceding gene: 157369932

Following gene: 157369934

Centisome position: 34.01

GC content: 54.05

Gene sequence:

>618_bases
ATGACGCTTGAAAATATCGCTTTAACGGGCCGGGTGCTGGGTGTGTTGTTGTATGCACCGCCAGAAAGTGAAGACGGTCA
ACAGCTGTTGGCAACCTTGTCTGAATCTGAGTGGGTCAAAGAGTGGCCGTATGGCGACGCCGAGCAGTTGCAGACGGCGG
CAGCACTGATTGCCACCGGCATTGAAGATAAACAAGAGGAGTCGTTGGCAGAGGCTTACCAACGTCTGTTTGTCGGGCCT
GACACCTTACCGGCTCCGTTATGGGGTTCGGTGTATCTGGACAAAGAGAACGTGCTGTTTGGCAATTCCACTTTGCGTCT
GCGCAGGTGGTTGCGTTCCAATGGTATCGACGCGCAACACGATCGCAATGAGCCGGAAGATCACATCGGTACCTTGTTGA
TGATGGTGGCATGGTTAGCCGAAGAGCGTCAGGGCGGGTTGGTGGAGCAATTGCTGACCAAACATTTGCTGCCTTGGGCA
CCGCGCTATCTGGAATTGCTGCAGGCGAATGCGCAACATCCTTTCTATCAGGGGCTGGCGCAATTGGCGCAGATCACTCT
GAGCGCCTGGGCTGCCGAATGCTCTGCTGAAGTTGAATCTTTAGAACTGCATTTCTGA

Upstream 100 bases:

>100_bases
GGTGTGTTCTACGGCCTGCATATGACCGTTGGCATGGCGGTAGCCGGTTAATATTGTAGTCAGGCACAGTTCGCTGTGCC
CTTAATAGGATCCTTGATTT

Downstream 100 bases:

>100_bases
TACAAAGGAACGGCCGCCGAAGCTGGCGGCCGTTCCTGGTTTACCCTCCACATCTAGCCATAAAAGGGCTGGTTATCGCC
AGTGCCTCCCTCTCTCTGTT

Product: twin-argninine leader-binding protein DmsD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTLENIALTGRVLGVLLYAPPESEDGQQLLATLSESEWVKEWPYGDAEQLQTAAALIATGIEDKQEESLAEAYQRLFVGP
DTLPAPLWGSVYLDKENVLFGNSTLRLRRWLRSNGIDAQHDRNEPEDHIGTLLMMVAWLAEERQGGLVEQLLTKHLLPWA
PRYLELLQANAQHPFYQGLAQLAQITLSAWAAECSAEVESLELHF

Sequences:

>Translated_205_residues
MTLENIALTGRVLGVLLYAPPESEDGQQLLATLSESEWVKEWPYGDAEQLQTAAALIATGIEDKQEESLAEAYQRLFVGP
DTLPAPLWGSVYLDKENVLFGNSTLRLRRWLRSNGIDAQHDRNEPEDHIGTLLMMVAWLAEERQGGLVEQLLTKHLLPWA
PRYLELLQANAQHPFYQGLAQLAQITLSAWAAECSAEVESLELHF
>Mature_204_residues
TLENIALTGRVLGVLLYAPPESEDGQQLLATLSESEWVKEWPYGDAEQLQTAAALIATGIEDKQEESLAEAYQRLFVGPD
TLPAPLWGSVYLDKENVLFGNSTLRLRRWLRSNGIDAQHDRNEPEDHIGTLLMMVAWLAEERQGGLVEQLLTKHLLPWAP
RYLELLQANAQHPFYQGLAQLAQITLSAWAAECSAEVESLELHF

Specific function: Binds to the twin-arginine signal peptide of dmsA and torA. Could be required for the biogenesis of DMSO reductase rather than for the targeting of dmsA to the inner membrane [H]

COG id: COG3381

COG function: function code R; Uncharacterized component of anaerobic dehydrogenases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Cytoplasm (By similarity). Note=Mainly cytoplasmic under aerobic conditions, and found in the inner membrane under anaerobic conditions (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the torD/dmsD family. DmsD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081942, Length=190, Percent_Identity=46.3157894736842, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1787272, Length=193, Percent_Identity=26.4248704663212, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020945 [H]

Pfam domain/function: PF02613 Nitrate_red_del [H]

EC number: NA

Molecular weight: Translated: 22991; Mature: 22860

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLENIALTGRVLGVLLYAPPESEDGQQLLATLSESEWVKEWPYGDAEQLQTAAALIATG
CCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
IEDKQEESLAEAYQRLFVGPDTLPAPLWGSVYLDKENVLFGNSTLRLRRWLRSNGIDAQH
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEECCHHHHHHHHHHHCCCCCCC
DRNEPEDHIGTLLMMVAWLAEERQGGLVEQLLTKHLLPWAPRYLELLQANAQHPFYQGLA
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHH
QLAQITLSAWAAECSAEVESLELHF
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLENIALTGRVLGVLLYAPPESEDGQQLLATLSESEWVKEWPYGDAEQLQTAAALIATG
CCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
IEDKQEESLAEAYQRLFVGPDTLPAPLWGSVYLDKENVLFGNSTLRLRRWLRSNGIDAQH
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEECCHHHHHHHHHHHCCCCCCC
DRNEPEDHIGTLLMMVAWLAEERQGGLVEQLLTKHLLPWAPRYLELLQANAQHPFYQGLA
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHH
QLAQITLSAWAAECSAEVESLELHF
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]