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The map label for this gene is gbh [H]

Identifier: 157369862

GI number: 157369862

Start: 1773902

End: 1774834

Strand: Direct

Name: gbh [H]

Synonym: Spro_1619

Alternate gene names: 157369862

Gene position: 1773902-1774834 (Clockwise)

Preceding gene: 157369860

Following gene: 157369863

Centisome position: 32.56

GC content: 60.13

Gene sequence:

>933_bases
ATGCTGAATCAACCCCAGAGTGGCAATGATATGCCGCGTTTTGCCGGTATCCCTACCATGATGCGTCTGCCCGTTGCCGA
CGATGCGCGAGGGCTGGATGCGGCCTTCGTCGGTATTCCTCTCGATATTGGCACTTCAAACCGCAGTGGCACGCGTTACG
GGCCGCGGCAAATCCGTCAGGAATCGGTGATGATCCGCCCATACAACATGGGCACCGCTGCCGCACCTTTTGAACGGCTG
CAGGTGGCCGACCTGGGGGATATCGCCATCAATCCTTACAGCCTGGAAGACAGCGTTCGTCGCATTGAGTTGGCCTATAA
CGGCATTCTGGCCCACGGCTGCATTCCACTGACGCTGGGGGGCGACCACACGCTGACGTTGCCTGTGCTGCGCGCCATGG
CCAGCCGATATGGCCCGGTCGGCTTGATTCACGTAGATGCTCACTCAGACACCAACGAAGAGATGTTTGGTGAAAAGTTG
GCACACGGAACAACTTTCCGGCGAGCCTTTGAAGAGGGGCTATTGCAGCCACAACGGGTCATTCAGATTGGCCTGCGCGG
CAGCGGCTATGAGGCTGATGATTTCGATTGGTCGCGCAAGCAGGGGTTCCGCGTGGTACCGGCAGAAGCCTGCTGGTACC
GCTCGTTGGCACCGCTGATGGAGGAAGTGCGCGAGCAGATGGGCAATGCGCCGGTTTATCTCAGTTTCGACATCGACGGC
CTGGATCCGGCATTTGCACCGGGCACCGGCACGCCGGAGGTCGGCGGGCTGTCGGTCTGGCAGGGCCTGGAAATTGTCAG
AGGCTGCCGGGGGCTAAACCTGGTCGGCAGCGACGTGGTGGAGGTTTCGCCGCCTTACGATCGTTCCGGCAACACCGCGC
TACTGGCGGCCAACCTGTTGTTTGAAATGCTGTGTGTACTGCCGTCGCGATAA

Upstream 100 bases:

>100_bases
TTACATCCCAAAGATGGAATGGTAGTCCTGTCAGGGGGCGGGTAGCCTGTATTTGTTATCCAAATGTTGAAATTATCTGA
CAGCCGAATAAGGAAAGATC

Downstream 100 bases:

>100_bases
GGCGACCGATAACCCGATCGGCGGAGCCGTTGCGCCTGATACCGAATAATAACAAGCATGCGGAGTGACCGATGAATCTC
GACCTGCTGGTAGTGGTGTT

Product: putative agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MLNQPQSGNDMPRFAGIPTMMRLPVADDARGLDAAFVGIPLDIGTSNRSGTRYGPRQIRQESVMIRPYNMGTAAAPFERL
QVADLGDIAINPYSLEDSVRRIELAYNGILAHGCIPLTLGGDHTLTLPVLRAMASRYGPVGLIHVDAHSDTNEEMFGEKL
AHGTTFRRAFEEGLLQPQRVIQIGLRGSGYEADDFDWSRKQGFRVVPAEACWYRSLAPLMEEVREQMGNAPVYLSFDIDG
LDPAFAPGTGTPEVGGLSVWQGLEIVRGCRGLNLVGSDVVEVSPPYDRSGNTALLAANLLFEMLCVLPSR

Sequences:

>Translated_310_residues
MLNQPQSGNDMPRFAGIPTMMRLPVADDARGLDAAFVGIPLDIGTSNRSGTRYGPRQIRQESVMIRPYNMGTAAAPFERL
QVADLGDIAINPYSLEDSVRRIELAYNGILAHGCIPLTLGGDHTLTLPVLRAMASRYGPVGLIHVDAHSDTNEEMFGEKL
AHGTTFRRAFEEGLLQPQRVIQIGLRGSGYEADDFDWSRKQGFRVVPAEACWYRSLAPLMEEVREQMGNAPVYLSFDIDG
LDPAFAPGTGTPEVGGLSVWQGLEIVRGCRGLNLVGSDVVEVSPPYDRSGNTALLAANLLFEMLCVLPSR
>Mature_310_residues
MLNQPQSGNDMPRFAGIPTMMRLPVADDARGLDAAFVGIPLDIGTSNRSGTRYGPRQIRQESVMIRPYNMGTAAAPFERL
QVADLGDIAINPYSLEDSVRRIELAYNGILAHGCIPLTLGGDHTLTLPVLRAMASRYGPVGLIHVDAHSDTNEEMFGEKL
AHGTTFRRAFEEGLLQPQRVIQIGLRGSGYEADDFDWSRKQGFRVVPAEACWYRSLAPLMEEVREQMGNAPVYLSFDIDG
LDPAFAPGTGTPEVGGLSVWQGLEIVRGCRGLNLVGSDVVEVSPPYDRSGNTALLAANLLFEMLCVLPSR

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=307, Percent_Identity=63.843648208469, Blast_Score=414, Evalue=1e-116,
Organism=Escherichia coli, GI1789306, Length=299, Percent_Identity=40.8026755852843, Blast_Score=197, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI71996843, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325146, Length=212, Percent_Identity=30.6603773584906, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 33789; Mature: 33789

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNQPQSGNDMPRFAGIPTMMRLPVADDARGLDAAFVGIPLDIGTSNRSGTRYGPRQIRQ
CCCCCCCCCCCCHHCCCCHHEECCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHC
ESVMIRPYNMGTAAAPFERLQVADLGDIAINPYSLEDSVRRIELAYNGILAHGCIPLTLG
CCEEEEEECCCCCCCCHHHEEECCCCCEEECCCCCHHHHHEEHHHHCCEEECCCEEEEEC
GDHTLTLPVLRAMASRYGPVGLIHVDAHSDTNEEMFGEKLAHGTTFRRAFEEGLLQPQRV
CCCEEHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHH
IQIGLRGSGYEADDFDWSRKQGFRVVPAEACWYRSLAPLMEEVREQMGNAPVYLSFDIDG
HEECCCCCCCCCCCCCCHHHCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
LDPAFAPGTGTPEVGGLSVWQGLEIVRGCRGLNLVGSDVVEVSPPYDRSGNTALLAANLL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCEEEHHHHHH
FEMLCVLPSR
HHHHHHCCCC
>Mature Secondary Structure
MLNQPQSGNDMPRFAGIPTMMRLPVADDARGLDAAFVGIPLDIGTSNRSGTRYGPRQIRQ
CCCCCCCCCCCCHHCCCCHHEECCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHC
ESVMIRPYNMGTAAAPFERLQVADLGDIAINPYSLEDSVRRIELAYNGILAHGCIPLTLG
CCEEEEEECCCCCCCCHHHEEECCCCCEEECCCCCHHHHHEEHHHHCCEEECCCEEEEEC
GDHTLTLPVLRAMASRYGPVGLIHVDAHSDTNEEMFGEKLAHGTTFRRAFEEGLLQPQRV
CCCEEHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHH
IQIGLRGSGYEADDFDWSRKQGFRVVPAEACWYRSLAPLMEEVREQMGNAPVYLSFDIDG
HEECCCCCCCCCCCCCCHHHCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
LDPAFAPGTGTPEVGGLSVWQGLEIVRGCRGLNLVGSDVVEVSPPYDRSGNTALLAANLL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCEEEHHHHHH
FEMLCVLPSR
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA