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The map label for this gene is prtE [H]

Identifier: 157369840

GI number: 157369840

Start: 1748151

End: 1749482

Strand: Direct

Name: prtE [H]

Synonym: Spro_1597

Alternate gene names: 157369840

Gene position: 1748151-1749482 (Clockwise)

Preceding gene: 157369839

Following gene: 157369841

Centisome position: 32.08

GC content: 53.0

Gene sequence:

>1332_bases
ATGTCTACGCACATTGGCGAGCCGCAAGACTCGTATTCAGAACAGATCCCACAGGATGAGCGGCGTTTTACCCGCATGGG
GTGGTTAGTGGTTGGGATTGGCCTGTTTGGCTTCTTCGCCTGGGCTGCGTTTGCACCTTTGGATAAAGGGGTCGCGTCAC
CAGGTTCGGTGACCGTTTCCGGCAATCGTAAAACCGTACAGGCCCCGGCCAGCGGCATCATCAAAAGTATCACGGTAAAA
GAAGGCGACAAGGTTAAAGCGGGCGAGGTGCTGGTGCAGTTGAGCCAGGTTCAGGCCCAGGCACAGGTTGACTCGCTTCG
TGACCAATATTACACCACGCTTGCCAGCGAAGGGCGTTTGCTGGCTGAACGTGATGGATTAAGCAAAGTCACTTTTTCTC
CTGTTTTTGAAACCATCCAGGCTCAGCCGCGGGTCGCTGAGATCATCGCATTGCAAACGCAGTTATTCTCTTCCCGTCGC
ATAGGGCTACAAAGCGAAGTTGACGGCTATAAACAGTCAATGGACGGCATGCGTTTCCAACTGAAGGGCCTGCAGGACTC
AAGGGTCAACAAGCAAATCCAGCTTTCCAGCCTGCGCGAACAGATGAACAGCATGAAGCAACTGGCGGCGGACGGTTATT
TACCGCGTAACCGTTATCTGGAGGTACAGCGTCAGTTTGCGGAAGTGAACAGCAGTATCGATGAAACCGTTGGGCGAATT
GGCCAGGTACAAAAACAGTTGCAGGAGTCTCAGCAGCGGATCGACCAACGCTTTGCCGACTATCAACGCGAAGTCAGAAC
TCAGTTGGCGCAAACGCAGATGGATGCCAGCGAGTTTAGAAACAAGCTGGAAATGGCGAATTTTGACCTCGGCAACACCG
CTATCAGTTCGCCGGTGGATGGGACTGTCGTTGGGTTAAATATCTTTACTCAGGGGGGCGTCGTGGGAGCGGGTGACCAC
CTGATGGACGTTGTACCCAGCCAGGCTACATTGGTGGTGGATTCACGCCTCAAGGTAGAGCTGATTGATAAAGTGTACAA
CGGGTTGCCGGTGGATTTGATGTTTACCGCCTTCAACCAAAACAAGACCCCGAAAATACCGGGGACGGTGACGTTGGTTT
CTGCCGACCGTCTGGTCGACAAGGCCAATGGCGAACCCTACTACCAAATGCAGGTCACGGTTTCCCCCGAGGGCATGAAA
TTGCTCAGTGGCGAAGACATCAAACCGGGGATGCCTGTGGAGGTGTTTGTGAAGACCGGCTCGCGCTCACTGTTGAGTTA
TCTGTTTAAACCTATTTTGGATCGCGCTCATACTTCATTAACCGAGGAATAA

Upstream 100 bases:

>100_bases
CTCCGAGCCGGACGAAGGCAATATTCCAAAAACTCAAATTAATTAAGCTGTGTACTTGCCGGGCGGCGCCAAAATGCCGC
CTGCAGTCAAAGGAGTTGGT

Downstream 100 bases:

>100_bases
TTTTGATTCAATTTAAACGACAGGTTGCTGGCCTTGCTATCAGTACCCTCTTGTTTGCGATAGCTGCGCCGGTTCATTCG
ATAGGGATTATAGACGCATA

Product: HlyD family type I secretion membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSTHIGEPQDSYSEQIPQDERRFTRMGWLVVGIGLFGFFAWAAFAPLDKGVASPGSVTVSGNRKTVQAPASGIIKSITVK
EGDKVKAGEVLVQLSQVQAQAQVDSLRDQYYTTLASEGRLLAERDGLSKVTFSPVFETIQAQPRVAEIIALQTQLFSSRR
IGLQSEVDGYKQSMDGMRFQLKGLQDSRVNKQIQLSSLREQMNSMKQLAADGYLPRNRYLEVQRQFAEVNSSIDETVGRI
GQVQKQLQESQQRIDQRFADYQREVRTQLAQTQMDASEFRNKLEMANFDLGNTAISSPVDGTVVGLNIFTQGGVVGAGDH
LMDVVPSQATLVVDSRLKVELIDKVYNGLPVDLMFTAFNQNKTPKIPGTVTLVSADRLVDKANGEPYYQMQVTVSPEGMK
LLSGEDIKPGMPVEVFVKTGSRSLLSYLFKPILDRAHTSLTEE

Sequences:

>Translated_443_residues
MSTHIGEPQDSYSEQIPQDERRFTRMGWLVVGIGLFGFFAWAAFAPLDKGVASPGSVTVSGNRKTVQAPASGIIKSITVK
EGDKVKAGEVLVQLSQVQAQAQVDSLRDQYYTTLASEGRLLAERDGLSKVTFSPVFETIQAQPRVAEIIALQTQLFSSRR
IGLQSEVDGYKQSMDGMRFQLKGLQDSRVNKQIQLSSLREQMNSMKQLAADGYLPRNRYLEVQRQFAEVNSSIDETVGRI
GQVQKQLQESQQRIDQRFADYQREVRTQLAQTQMDASEFRNKLEMANFDLGNTAISSPVDGTVVGLNIFTQGGVVGAGDH
LMDVVPSQATLVVDSRLKVELIDKVYNGLPVDLMFTAFNQNKTPKIPGTVTLVSADRLVDKANGEPYYQMQVTVSPEGMK
LLSGEDIKPGMPVEVFVKTGSRSLLSYLFKPILDRAHTSLTEE
>Mature_442_residues
STHIGEPQDSYSEQIPQDERRFTRMGWLVVGIGLFGFFAWAAFAPLDKGVASPGSVTVSGNRKTVQAPASGIIKSITVKE
GDKVKAGEVLVQLSQVQAQAQVDSLRDQYYTTLASEGRLLAERDGLSKVTFSPVFETIQAQPRVAEIIALQTQLFSSRRI
GLQSEVDGYKQSMDGMRFQLKGLQDSRVNKQIQLSSLREQMNSMKQLAADGYLPRNRYLEVQRQFAEVNSSIDETVGRIG
QVQKQLQESQQRIDQRFADYQREVRTQLAQTQMDASEFRNKLEMANFDLGNTAISSPVDGTVVGLNIFTQGGVVGAGDHL
MDVVPSQATLVVDSRLKVELIDKVYNGLPVDLMFTAFNQNKTPKIPGTVTLVSADRLVDKANGEPYYQMQVTVSPEGMKL
LSGEDIKPGMPVEVFVKTGSRSLLSYLFKPILDRAHTSLTEE

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49026; Mature: 48895

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHIGEPQDSYSEQIPQDERRFTRMGWLVVGIGLFGFFAWAAFAPLDKGVASPGSVTVS
CCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
GNRKTVQAPASGIIKSITVKEGDKVKAGEVLVQLSQVQAQAQVDSLRDQYYTTLASEGRL
CCCEEEECCHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
LAERDGLSKVTFSPVFETIQAQPRVAEIIALQTQLFSSRRIGLQSEVDGYKQSMDGMRFQ
EECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEE
LKGLQDSRVNKQIQLSSLREQMNSMKQLAADGYLPRNRYLEVQRQFAEVNSSIDETVGRI
ECCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
GQVQKQLQESQQRIDQRFADYQREVRTQLAQTQMDASEFRNKLEMANFDLGNTAISSPVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCC
GTVVGLNIFTQGGVVGAGDHLMDVVPSQATLVVDSRLKVELIDKVYNGLPVDLMFTAFNQ
CEEEEEEEEECCCEECCCCHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEECC
NKTPKIPGTVTLVSADRLVDKANGEPYYQMQVTVSPEGMKLLSGEDIKPGMPVEVFVKTG
CCCCCCCCEEEEEEHHHHHHHCCCCCEEEEEEEECCCCCEECCCCCCCCCCCEEEEEECC
SRSLLSYLFKPILDRAHTSLTEE
CHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STHIGEPQDSYSEQIPQDERRFTRMGWLVVGIGLFGFFAWAAFAPLDKGVASPGSVTVS
CCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
GNRKTVQAPASGIIKSITVKEGDKVKAGEVLVQLSQVQAQAQVDSLRDQYYTTLASEGRL
CCCEEEECCHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
LAERDGLSKVTFSPVFETIQAQPRVAEIIALQTQLFSSRRIGLQSEVDGYKQSMDGMRFQ
EECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEE
LKGLQDSRVNKQIQLSSLREQMNSMKQLAADGYLPRNRYLEVQRQFAEVNSSIDETVGRI
ECCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
GQVQKQLQESQQRIDQRFADYQREVRTQLAQTQMDASEFRNKLEMANFDLGNTAISSPVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCC
GTVVGLNIFTQGGVVGAGDHLMDVVPSQATLVVDSRLKVELIDKVYNGLPVDLMFTAFNQ
CEEEEEEEEECCCEECCCCHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEEECC
NKTPKIPGTVTLVSADRLVDKANGEPYYQMQVTVSPEGMKLLSGEDIKPGMPVEVFVKTG
CCCCCCCCEEEEEEHHHHHHHCCCCCEEEEEEEECCCCCEECCCCCCCCCCCEEEEEECC
SRSLLSYLFKPILDRAHTSLTEE
CHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]