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The map label for this gene is gsiD [H]

Identifier: 157369796

GI number: 157369796

Start: 1693294

End: 1694202

Strand: Direct

Name: gsiD [H]

Synonym: Spro_1553

Alternate gene names: 157369796

Gene position: 1693294-1694202 (Clockwise)

Preceding gene: 157369795

Following gene: 157369797

Centisome position: 31.08

GC content: 58.53

Gene sequence:

>909_bases
ATGATTAAGCATTGGCGACGCAACGCCGCAATGAAGGCGATGCCGACGATTAACCCTAACGCGGTGCGCACACCGTGGCA
TGAGTTCTGGCGGCGGTTCCGCCAGCAACGTGTGGCGCTGGTCGCCGGGCTGTTGGTGCTGTTGCTGGTGGTTGCCGCGT
TATTGGCACCTTACCTGGTGCCGTTTGATGCGGAAAACTACTTTGATTATGACCGCCTGAACGAAGGCCCTTCGCTGGTG
CACTGGTTGGGGGTAGATTCCCTTGGGCGAGATATTTTCAGCCGCATTCTGATGGGCGCTCGTATTTCGCTGGCCGCCGG
GGTGTTCTCGGTGCTGGTCGGCGGGCTGATCGGCACGCTGCTGGGCCTGTTGGCCGGTTATTATGAGGGCTGGTGGGACC
GTATCACCATGCGTATCTGTGACGTGCTGTTTGCCTTTCCCGGTATTTTATTGGCGATTGGCGTGGTAGCGATTATGGGC
AGCGGTATGTCCAACGTGATCATTGCAGTGGCGATTTTCAGCATTCCGGCGTTTGCCCGGCTGGTACGCGGCAATACGCT
GGTATTGAAGCACCTGACCTATATCGAGTCGGCGCGCAGCATCGGGGCTTCCGACTGGACCATCATCCTGCGACATATAC
TGCCGGGGACGATTTCGTCGATTGTGGTGTATTTTACCATGCGTATCGGCACCTCGATCATTACCGCCGCCAGCCTGTCA
TTCCTCGGCCTGGGCGCGCAGCCACCAACGCCGGAGTGGGGTGCGATGCTCAATGAGGCTCGGGCGGACATGGTGATGGC
ACCGCACGTGGCGATTTTCCCCAGTCTGGCAATATTCATCACCGTACTGGCGTTCAACCTGCTGGGTGACGGGCTGCGCG
ACGCGCTGGATCCGAAATTAAAAGGGTAG

Upstream 100 bases:

>100_bases
GGTTTTGCTGTTCTCGCTAGAGTTTATTCTGATTAACCTGTTGGTGGACCTGCTGTATGCGGCAATTAACCCGGCGATAC
GCTACAAATGAGGACGCGGG

Downstream 100 bases:

>100_bases
AATAAGGTCAAATTAATAGCGGTTAATATGCGGGGTGTTAATCGTTTAATTAACTGAGACATTTTAACGTATTCGGTAAA
TCAACCGAATACGTTAATAT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MIKHWRRNAAMKAMPTINPNAVRTPWHEFWRRFRQQRVALVAGLLVLLLVVAALLAPYLVPFDAENYFDYDRLNEGPSLV
HWLGVDSLGRDIFSRILMGARISLAAGVFSVLVGGLIGTLLGLLAGYYEGWWDRITMRICDVLFAFPGILLAIGVVAIMG
SGMSNVIIAVAIFSIPAFARLVRGNTLVLKHLTYIESARSIGASDWTIILRHILPGTISSIVVYFTMRIGTSIITAASLS
FLGLGAQPPTPEWGAMLNEARADMVMAPHVAIFPSLAIFITVLAFNLLGDGLRDALDPKLKG

Sequences:

>Translated_302_residues
MIKHWRRNAAMKAMPTINPNAVRTPWHEFWRRFRQQRVALVAGLLVLLLVVAALLAPYLVPFDAENYFDYDRLNEGPSLV
HWLGVDSLGRDIFSRILMGARISLAAGVFSVLVGGLIGTLLGLLAGYYEGWWDRITMRICDVLFAFPGILLAIGVVAIMG
SGMSNVIIAVAIFSIPAFARLVRGNTLVLKHLTYIESARSIGASDWTIILRHILPGTISSIVVYFTMRIGTSIITAASLS
FLGLGAQPPTPEWGAMLNEARADMVMAPHVAIFPSLAIFITVLAFNLLGDGLRDALDPKLKG
>Mature_302_residues
MIKHWRRNAAMKAMPTINPNAVRTPWHEFWRRFRQQRVALVAGLLVLLLVVAALLAPYLVPFDAENYFDYDRLNEGPSLV
HWLGVDSLGRDIFSRILMGARISLAAGVFSVLVGGLIGTLLGLLAGYYEGWWDRITMRICDVLFAFPGILLAIGVVAIMG
SGMSNVIIAVAIFSIPAFARLVRGNTLVLKHLTYIESARSIGASDWTIILRHILPGTISSIVVYFTMRIGTSIITAASLS
FLGLGAQPPTPEWGAMLNEARADMVMAPHVAIFPSLAIFITVLAFNLLGDGLRDALDPKLKG

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=299, Percent_Identity=79.933110367893, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=39.2452830188679, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1789964, Length=283, Percent_Identity=40.6360424028269, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787498, Length=279, Percent_Identity=37.6344086021505, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1789889, Length=245, Percent_Identity=38.7755102040816, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787549, Length=286, Percent_Identity=33.2167832167832, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788505, Length=225, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33027; Mature: 33027

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKHWRRNAAMKAMPTINPNAVRTPWHEFWRRFRQQRVALVAGLLVLLLVVAALLAPYLV
CCCCHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PFDAENYFDYDRLNEGPSLVHWLGVDSLGRDIFSRILMGARISLAAGVFSVLVGGLIGTL
CCCCCCCCCHHHCCCCCCEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLLAGYYEGWWDRITMRICDVLFAFPGILLAIGVVAIMGSGMSNVIIAVAIFSIPAFAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVRGNTLVLKHLTYIESARSIGASDWTIILRHILPGTISSIVVYFTMRIGTSIITAASLS
HHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLGAQPPTPEWGAMLNEARADMVMAPHVAIFPSLAIFITVLAFNLLGDGLRDALDPKL
HHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KG
CC
>Mature Secondary Structure
MIKHWRRNAAMKAMPTINPNAVRTPWHEFWRRFRQQRVALVAGLLVLLLVVAALLAPYLV
CCCCHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PFDAENYFDYDRLNEGPSLVHWLGVDSLGRDIFSRILMGARISLAAGVFSVLVGGLIGTL
CCCCCCCCCHHHCCCCCCEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLLAGYYEGWWDRITMRICDVLFAFPGILLAIGVVAIMGSGMSNVIIAVAIFSIPAFAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LVRGNTLVLKHLTYIESARSIGASDWTIILRHILPGTISSIVVYFTMRIGTSIITAASLS
HHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLGAQPPTPEWGAMLNEARADMVMAPHVAIFPSLAIFITVLAFNLLGDGLRDALDPKL
HHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]