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The map label for this gene is prlC [C]

Identifier: 157369711

GI number: 157369711

Start: 1600127

End: 1601983

Strand: Direct

Name: prlC [C]

Synonym: Spro_1468

Alternate gene names: 157369711

Gene position: 1600127-1601983 (Clockwise)

Preceding gene: 157369710

Following gene: 157369713

Centisome position: 29.37

GC content: 58.43

Gene sequence:

>1857_bases
ATGCAACAGGCTCTCGATTATTTCAATCAATTGAATCAGGATTATCTTGAGGTTCACCGCACCAAAGAAGATCTGTTCTG
GCACAACTATATGGGCACCGGTGGTGACGATGTTTCAACACACTTTTCGGCGGCGGAAAGCGCTTATAAACGCTTTATCG
CCGAACCGCGTCGATTGGCGGAAATTCGTCAGTTGCTGGCTGGGCTGGAAGTTCTGCCGCAGGACGCACAGCGCGATGCG
CTGCAACATGGGCTGAATGGCTGGCTGCGTTTCTTTGACTGTAACGCCATTGAAGATGCCGAGGCCCAGACGCTGCTGGA
TCAAATCATCAGTGCCGAGGCGGACTTGTATACCCGGCGCAAGGCCAACCCGGTCAGCCATCTGAATGCCGCCGGGCAGC
GGGTGAACGCCTCGCTCGGTGAGTTGCTGACCAACCAGGCCACCAATGAAAATGAAGACTACCGCCGCAGTTCGCAGAAT
GCGCTGCGTGAGCTGGAACAGTGGCTATTGCACAACGGTTTGCCGGAGCTGATTAGCCTGCGTAACCGCTTTGCGCGCCA
GATGGGGTTTCGCAACTATTTCGACTACAAGGTCAACAAGACCGAGCGCATGACGCCGGAGCAGTTGTTCACCATTCTGG
ATCGTTTTGAGCAGCAAACCCGTGAGGCCAATTCACGCAGTCTGCAGCAGTTGGCGGCGCAAAAGGGCGAGCAGGCGCTG
CAACCCTGGAACATCCGTTTTGCCAGCGCCGGTGACGTGACCCGACAACTGGATCCTTACTTCCCGTTTGCCCAGTCGCT
TGAACGTTGGATCAACAGCTTCAAACGGTTGCACGTCGGTTTTCGTGGCGCGCAGATGGATCTCGACCTGTTGGTGCGTC
AGGGCAAGTATGAAAACGGCTTTATGCACGGCCCGGTACCGCCGTTTATCCAGCAGGGGAAATGGCTGCCGGCGCGGATT
AACTTCACCAGTCTGGCGCAGCCGGATCAGGTGGGCAGTGGCGCTCATGGGCTCAATACGCTGTTCCATGAGGGCGGCCA
TGCTGCGCACTTTGCCAATATCTGCCAGAACGCACCCTGCTTCTCGCAGGAGTTCCCGCCGACCTCAATGGCCTATGCGG
AAACCCAGTCGATGTTCTGTGACAGCCTGCTGGACGACGCCGATTGGCTGAAACGCTATGCGAAAAACGCCGCCGGTGAG
CCGGTGCCGGATGCATTGATTGAGGCCAGTATTGCGGCACGCCAGCCGATGCGTGCGTTCAACGAACGTCATATTCTGCT
GGTGCCTTACTTTGAGTGGGCGTTGTATCAGTGGGATGAGCAACAGCTGACACCAGAGGCGATTACCGCACTGGCGCGCG
AGGTTGAGCACAAAATTCTGGGCATTAGCGGCAGCCCGCGTCCGACACTGGCGATCCCGCATTTGTTGTCGCTGGAGTCG
GCCTGTTCCTATCAGGGGTATCTGCTGGCACTGATGGCGGTCGAACAGACGCGCCATTTCTTCTTGCAGCGTGACGGCTA
TCTTACCGATAACCCGGCGATTGGCCCGGACCTGGCGCATCACTACTGGCTACCGGGTAACGGTGTCAGCCATGATGAGA
CGCTACGCAGCCTGACCGGCGAAGGCTTTAACCCGGACTATCTGGCGCAGGCCTGTAACCAGACTGTGGCGCAGGCGTGG
CAGGATGCTCAGCAGACCATCGCTGCTGCCGCTGCCCGGCCGCAACCGGCGGCGGACTTCGACCTGGCGGCGCATATCCG
CGTGGTGGATGGCGAGCAGGTGCTGGCGGATAACGCCGAGGGCGATGAAAAGATGTGCCGTGACTTCGCCGCAGCGATTA
ACGCACGTCTGGCCTGA

Upstream 100 bases:

>100_bases
GGTGAGGTTGACACCCTGGAACAGGGTTTGGAACGTTTACGCAGCGCGTAAATCCCTTGGCTATACTGGAACACTTCGCT
ATTCGGCTGAAAGGATGGTT

Downstream 100 bases:

>100_bases
AATCGCTGAACAAGCCCGCCGCGTGTCTGCACCGGCGGGCTTTTTATTACCACCCGTGAGCGATCAGCGCTTTTGCGCAT
CCGGGCGGGTCATGTCGAAA

Product: peptidase M3A and M3B thimet/oligopeptidase F

Products: hydrolyzed oligopeptide [C]

Alternate protein names: Peptidase; Peptidase M3A And M3B Thimet/Oligopeptidase F; M3 Family Peptidase

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MQQALDYFNQLNQDYLEVHRTKEDLFWHNYMGTGGDDVSTHFSAAESAYKRFIAEPRRLAEIRQLLAGLEVLPQDAQRDA
LQHGLNGWLRFFDCNAIEDAEAQTLLDQIISAEADLYTRRKANPVSHLNAAGQRVNASLGELLTNQATNENEDYRRSSQN
ALRELEQWLLHNGLPELISLRNRFARQMGFRNYFDYKVNKTERMTPEQLFTILDRFEQQTREANSRSLQQLAAQKGEQAL
QPWNIRFASAGDVTRQLDPYFPFAQSLERWINSFKRLHVGFRGAQMDLDLLVRQGKYENGFMHGPVPPFIQQGKWLPARI
NFTSLAQPDQVGSGAHGLNTLFHEGGHAAHFANICQNAPCFSQEFPPTSMAYAETQSMFCDSLLDDADWLKRYAKNAAGE
PVPDALIEASIAARQPMRAFNERHILLVPYFEWALYQWDEQQLTPEAITALAREVEHKILGISGSPRPTLAIPHLLSLES
ACSYQGYLLALMAVEQTRHFFLQRDGYLTDNPAIGPDLAHHYWLPGNGVSHDETLRSLTGEGFNPDYLAQACNQTVAQAW
QDAQQTIAAAAARPQPAADFDLAAHIRVVDGEQVLADNAEGDEKMCRDFAAAINARLA

Sequences:

>Translated_618_residues
MQQALDYFNQLNQDYLEVHRTKEDLFWHNYMGTGGDDVSTHFSAAESAYKRFIAEPRRLAEIRQLLAGLEVLPQDAQRDA
LQHGLNGWLRFFDCNAIEDAEAQTLLDQIISAEADLYTRRKANPVSHLNAAGQRVNASLGELLTNQATNENEDYRRSSQN
ALRELEQWLLHNGLPELISLRNRFARQMGFRNYFDYKVNKTERMTPEQLFTILDRFEQQTREANSRSLQQLAAQKGEQAL
QPWNIRFASAGDVTRQLDPYFPFAQSLERWINSFKRLHVGFRGAQMDLDLLVRQGKYENGFMHGPVPPFIQQGKWLPARI
NFTSLAQPDQVGSGAHGLNTLFHEGGHAAHFANICQNAPCFSQEFPPTSMAYAETQSMFCDSLLDDADWLKRYAKNAAGE
PVPDALIEASIAARQPMRAFNERHILLVPYFEWALYQWDEQQLTPEAITALAREVEHKILGISGSPRPTLAIPHLLSLES
ACSYQGYLLALMAVEQTRHFFLQRDGYLTDNPAIGPDLAHHYWLPGNGVSHDETLRSLTGEGFNPDYLAQACNQTVAQAW
QDAQQTIAAAAARPQPAADFDLAAHIRVVDGEQVLADNAEGDEKMCRDFAAAINARLA
>Mature_618_residues
MQQALDYFNQLNQDYLEVHRTKEDLFWHNYMGTGGDDVSTHFSAAESAYKRFIAEPRRLAEIRQLLAGLEVLPQDAQRDA
LQHGLNGWLRFFDCNAIEDAEAQTLLDQIISAEADLYTRRKANPVSHLNAAGQRVNASLGELLTNQATNENEDYRRSSQN
ALRELEQWLLHNGLPELISLRNRFARQMGFRNYFDYKVNKTERMTPEQLFTILDRFEQQTREANSRSLQQLAAQKGEQAL
QPWNIRFASAGDVTRQLDPYFPFAQSLERWINSFKRLHVGFRGAQMDLDLLVRQGKYENGFMHGPVPPFIQQGKWLPARI
NFTSLAQPDQVGSGAHGLNTLFHEGGHAAHFANICQNAPCFSQEFPPTSMAYAETQSMFCDSLLDDADWLKRYAKNAAGE
PVPDALIEASIAARQPMRAFNERHILLVPYFEWALYQWDEQQLTPEAITALAREVEHKILGISGSPRPTLAIPHLLSLES
ACSYQGYLLALMAVEQTRHFFLQRDGYLTDNPAIGPDLAHHYWLPGNGVSHDETLRSLTGEGFNPDYLAQACNQTVAQAW
QDAQQTIAAAAARPQPAADFDLAAHIRVVDGEQVLADNAEGDEKMCRDFAAAINARLA

Specific function: May Play A Specific Role In The Degradation Of Signal Peptides After They Are Released From Precursor Forms Of Secreted Proteins. Can Cleave N-Acetyl-L-Ala(4). [C]

COG id: COG1164

COG function: function code E; Oligoendopeptidase F

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.4.24.70 [C]

Molecular weight: Translated: 69761; Mature: 69761

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQALDYFNQLNQDYLEVHRTKEDLFWHNYMGTGGDDVSTHFSAAESAYKRFIAEPRRLA
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHH
EIRQLLAGLEVLPQDAQRDALQHGLNGWLRFFDCNAIEDAEAQTLLDQIISAEADLYTRR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KANPVSHLNAAGQRVNASLGELLTNQATNENEDYRRSSQNALRELEQWLLHNGLPELISL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RNRFARQMGFRNYFDYKVNKTERMTPEQLFTILDRFEQQTREANSRSLQQLAAQKGEQAL
HHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QPWNIRFASAGDVTRQLDPYFPFAQSLERWINSFKRLHVGFRGAQMDLDLLVRQGKYENG
CCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
FMHGPVPPFIQQGKWLPARINFTSLAQPDQVGSGAHGLNTLFHEGGHAAHFANICQNAPC
CCCCCCCHHHHCCCCCEEECCHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCC
FSQEFPPTSMAYAETQSMFCDSLLDDADWLKRYAKNAAGEPVPDALIEASIAARQPMRAF
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
NERHILLVPYFEWALYQWDEQQLTPEAITALAREVEHKILGISGSPRPTLAIPHLLSLES
CCCCEEEEEHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
ACSYQGYLLALMAVEQTRHFFLQRDGYLTDNPAIGPDLAHHYWLPGNGVSHDETLRSLTG
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHCC
EGFNPDYLAQACNQTVAQAWQDAQQTIAAAAARPQPAADFDLAAHIRVVDGEQVLADNAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHCCCCC
GDEKMCRDFAAAINARLA
CHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQQALDYFNQLNQDYLEVHRTKEDLFWHNYMGTGGDDVSTHFSAAESAYKRFIAEPRRLA
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHH
EIRQLLAGLEVLPQDAQRDALQHGLNGWLRFFDCNAIEDAEAQTLLDQIISAEADLYTRR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KANPVSHLNAAGQRVNASLGELLTNQATNENEDYRRSSQNALRELEQWLLHNGLPELISL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RNRFARQMGFRNYFDYKVNKTERMTPEQLFTILDRFEQQTREANSRSLQQLAAQKGEQAL
HHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QPWNIRFASAGDVTRQLDPYFPFAQSLERWINSFKRLHVGFRGAQMDLDLLVRQGKYENG
CCCCEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
FMHGPVPPFIQQGKWLPARINFTSLAQPDQVGSGAHGLNTLFHEGGHAAHFANICQNAPC
CCCCCCCHHHHCCCCCEEECCHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCC
FSQEFPPTSMAYAETQSMFCDSLLDDADWLKRYAKNAAGEPVPDALIEASIAARQPMRAF
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
NERHILLVPYFEWALYQWDEQQLTPEAITALAREVEHKILGISGSPRPTLAIPHLLSLES
CCCCEEEEEHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
ACSYQGYLLALMAVEQTRHFFLQRDGYLTDNPAIGPDLAHHYWLPGNGVSHDETLRSLTG
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHCC
EGFNPDYLAQACNQTVAQAWQDAQQTIAAAAARPQPAADFDLAAHIRVVDGEQVLADNAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHCCCCC
GDEKMCRDFAAAINARLA
CHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Co2+; Mn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oligopeptide; H2O [C]

Specific reaction: Oligopeptide + H2O = Hydrolyzed oligopeptide [C]

General reaction: Hydrolysis of peptide bond [C]

Inhibitor: Cu2+; EDTA; Ni2+; Zn2+ [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA