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The map label for this gene is yebQ [C]

Identifier: 157369696

GI number: 157369696

Start: 1585401

End: 1586855

Strand: Direct

Name: yebQ [C]

Synonym: Spro_1453

Alternate gene names: 157369696

Gene position: 1585401-1586855 (Clockwise)

Preceding gene: 157369692

Following gene: 157369697

Centisome position: 29.1

GC content: 61.72

Gene sequence:

>1455_bases
GTGATAACCAACGATGATAGCCGCTGGGCCGATCTATTTTCCGGCAAAAATGGTGCCAGTGCGATCGCGCTCTCACTCGG
CGTAGCGCTGCATGCAATCAATATTCTGGTCGCTACCACCATTCTGCCCTCGGTGGTGCAGGATATCGGCGGGCTGAGTC
TGTATGCCTGGAATACGACGCTGTTTGTGGTGGCGTCGATTCTGGGTTCGGCATTATCGGCTCGTTTACTCAGCGGTTAC
GGGGCTCGCAGTGCCTACGTGGTGGCGTCACTGTTCTTTATTGCCGGAGCGATGCTGTGCGCGCTGGCGCCGTCAATGCC
GGTGATGCTGCTCGGCCGAACCGTGCAGGGCTTCGGCGGCGGGCTGATTTTCGCGCTTTCGTACGCCATGATCAATCTGG
TATTTGAGCAAAAACTATGGCCGCGGGCGATGGCGCTGATCTCGGCAATGTGGGGCATCGCGACCCTGGTAGGGCCGGCG
GTGGGCGGCATTTTTGCCGAACTGAATGCCTGGCGCTGGGCCTTTGGCATCCTGTTGCCGGTGATGGTGCTGTACGCCGG
GTTTACCTTCCTGATCCTGCCAAAAGGCAAACCGCAGCAACAGGCGGCACCGCTGCCGCTGGCTCAGCTGCTGCTGTTGG
CGACGGCGGTAATGGTGGTGTCCGCCGGTAGCCTGGCGGACAGCGCGTGGGTCAATCTTGGCGGCATTGCGTTGGCCGTG
CTGATGATGGCCTGGCTGATACAGCGTGAAGCGCACTCCCGCGCCCGATTGCTGCCGAAGGGGGCTTTGCGCCGCGGTTC
GCCGCTGGCCTCGTTGTATATCACCGTCTCTCTGCTGGTGGTGGGCATGACCAGTGAAATCTTCGTGCCTTATTTCCTGC
AAACCCTGCACGGCCAGTCCCCGCTGATTTCCGGTTATATCGCGGCCACTATGGCTGCGGGGTGGACGTTATCGGAAATC
CTCAGTTCCGGCTGGCGCAGTGCGGGCATCCGCCGGGCCATTGTCAGCGGGCCGATGTTGGTGTTGGTGGGGCTACTGGC
ATTGGGCCTGCTGATGCCGATACCTTCTGGCGGCCATTGGGCAGGGCTGACGCCGATTGTGATTGCGCTGACGCTGGTGG
GCTTTGGTATTGGTTTCGGCTGGCCGCATCTGTTGACGCGTATTCTGCAGGTTTCGCCTGAGGCCGATAAGGATATTGCC
GGGGCGTCGATCACCACGGTGCAACTGTTTGCGACCGCCTTTGGGGCTGCGTTGGCCGGGATGATTGCCAACCTGGCCGG
GTTAAATGTGCCGGGTGGTGCGCAGGGCGCAGCCTCCGCTGCTCGCTGGCTGTTCCTGCTGTTTGCATTGGCGCCGCTGC
TGGCGGTGTTCAGTGCCTGGCGCTGCGCGGCGATCGCACCGCCGGTTGCCGACAGCGACAAGCAGGTACCAGAGTCGTCG
GCTCTGCCGTCATAA

Upstream 100 bases:

>100_bases
CTCCGCCTCGCCCTACTCTTATTCCAAGATAATTCTTGTTAAATTTAACGCAATATCACCCTTAACTCAATGCCATTCCT
CTGAAAACAGGACGACAACT

Downstream 100 bases:

>100_bases
CGGCGAAAGACTTTTCGCCAAGTTGTAGTGCCAGTTAAAAATCTGGTTGACGAATCCCGTATTTGAGATTATTTCTCTTA
TATGGGATTTTTTGTATCAG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MITNDDSRWADLFSGKNGASAIALSLGVALHAINILVATTILPSVVQDIGGLSLYAWNTTLFVVASILGSALSARLLSGY
GARSAYVVASLFFIAGAMLCALAPSMPVMLLGRTVQGFGGGLIFALSYAMINLVFEQKLWPRAMALISAMWGIATLVGPA
VGGIFAELNAWRWAFGILLPVMVLYAGFTFLILPKGKPQQQAAPLPLAQLLLLATAVMVVSAGSLADSAWVNLGGIALAV
LMMAWLIQREAHSRARLLPKGALRRGSPLASLYITVSLLVVGMTSEIFVPYFLQTLHGQSPLISGYIAATMAAGWTLSEI
LSSGWRSAGIRRAIVSGPMLVLVGLLALGLLMPIPSGGHWAGLTPIVIALTLVGFGIGFGWPHLLTRILQVSPEADKDIA
GASITTVQLFATAFGAALAGMIANLAGLNVPGGAQGAASAARWLFLLFALAPLLAVFSAWRCAAIAPPVADSDKQVPESS
ALPS

Sequences:

>Translated_484_residues
MITNDDSRWADLFSGKNGASAIALSLGVALHAINILVATTILPSVVQDIGGLSLYAWNTTLFVVASILGSALSARLLSGY
GARSAYVVASLFFIAGAMLCALAPSMPVMLLGRTVQGFGGGLIFALSYAMINLVFEQKLWPRAMALISAMWGIATLVGPA
VGGIFAELNAWRWAFGILLPVMVLYAGFTFLILPKGKPQQQAAPLPLAQLLLLATAVMVVSAGSLADSAWVNLGGIALAV
LMMAWLIQREAHSRARLLPKGALRRGSPLASLYITVSLLVVGMTSEIFVPYFLQTLHGQSPLISGYIAATMAAGWTLSEI
LSSGWRSAGIRRAIVSGPMLVLVGLLALGLLMPIPSGGHWAGLTPIVIALTLVGFGIGFGWPHLLTRILQVSPEADKDIA
GASITTVQLFATAFGAALAGMIANLAGLNVPGGAQGAASAARWLFLLFALAPLLAVFSAWRCAAIAPPVADSDKQVPESS
ALPS
>Mature_484_residues
MITNDDSRWADLFSGKNGASAIALSLGVALHAINILVATTILPSVVQDIGGLSLYAWNTTLFVVASILGSALSARLLSGY
GARSAYVVASLFFIAGAMLCALAPSMPVMLLGRTVQGFGGGLIFALSYAMINLVFEQKLWPRAMALISAMWGIATLVGPA
VGGIFAELNAWRWAFGILLPVMVLYAGFTFLILPKGKPQQQAAPLPLAQLLLLATAVMVVSAGSLADSAWVNLGGIALAV
LMMAWLIQREAHSRARLLPKGALRRGSPLASLYITVSLLVVGMTSEIFVPYFLQTLHGQSPLISGYIAATMAAGWTLSEI
LSSGWRSAGIRRAIVSGPMLVLVGLLALGLLMPIPSGGHWAGLTPIVIALTLVGFGIGFGWPHLLTRILQVSPEADKDIA
GASITTVQLFATAFGAALAGMIANLAGLNVPGGAQGAASAARWLFLLFALAPLLAVFSAWRCAAIAPPVADSDKQVPESS
ALPS

Specific function: Could be involved in fluoroquinolones efflux [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=422, Percent_Identity=25.3554502369668, Blast_Score=92, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6322958, Length=159, Percent_Identity=30.8176100628931, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6321663, Length=148, Percent_Identity=29.7297297297297, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325455, Length=175, Percent_Identity=27.4285714285714, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50307; Mature: 50307

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITNDDSRWADLFSGKNGASAIALSLGVALHAINILVATTILPSVVQDIGGLSLYAWNTT
CCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHH
LFVVASILGSALSARLLSGYGARSAYVVASLFFIAGAMLCALAPSMPVMLLGRTVQGFGG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHCCC
GLIFALSYAMINLVFEQKLWPRAMALISAMWGIATLVGPAVGGIFAELNAWRWAFGILLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMVLYAGFTFLILPKGKPQQQAAPLPLAQLLLLATAVMVVSAGSLADSAWVNLGGIALAV
HHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LMMAWLIQREAHSRARLLPKGALRRGSPLASLYITVSLLVVGMTSEIFVPYFLQTLHGQS
HHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLISGYIAATMAAGWTLSEILSSGWRSAGIRRAIVSGPMLVLVGLLALGLLMPIPSGGHW
CHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCC
AGLTPIVIALTLVGFGIGFGWPHLLTRILQVSPEADKDIAGASITTVQLFATAFGAALAG
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MIANLAGLNVPGGAQGAASAARWLFLLFALAPLLAVFSAWRCAAIAPPVADSDKQVPESS
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ALPS
CCCC
>Mature Secondary Structure
MITNDDSRWADLFSGKNGASAIALSLGVALHAINILVATTILPSVVQDIGGLSLYAWNTT
CCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHH
LFVVASILGSALSARLLSGYGARSAYVVASLFFIAGAMLCALAPSMPVMLLGRTVQGFGG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHCCC
GLIFALSYAMINLVFEQKLWPRAMALISAMWGIATLVGPAVGGIFAELNAWRWAFGILLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMVLYAGFTFLILPKGKPQQQAAPLPLAQLLLLATAVMVVSAGSLADSAWVNLGGIALAV
HHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LMMAWLIQREAHSRARLLPKGALRRGSPLASLYITVSLLVVGMTSEIFVPYFLQTLHGQS
HHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLISGYIAATMAAGWTLSEILSSGWRSAGIRRAIVSGPMLVLVGLLALGLLMPIPSGGHW
CHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCC
AGLTPIVIALTLVGFGIGFGWPHLLTRILQVSPEADKDIAGASITTVQLFATAFGAALAG
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MIANLAGLNVPGGAQGAASAARWLFLLFALAPLLAVFSAWRCAAIAPPVADSDKQVPESS
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ALPS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]