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The map label for this gene is ansP [H]

Identifier: 157369590

GI number: 157369590

Start: 1477531

End: 1478994

Strand: Reverse

Name: ansP [H]

Synonym: Spro_1347

Alternate gene names: 157369590

Gene position: 1478994-1477531 (Counterclockwise)

Preceding gene: 157369591

Following gene: 157369588

Centisome position: 27.14

GC content: 58.95

Gene sequence:

>1464_bases
ATGCAATCACAAAAAAAATCGGCGCATGAGCAACATGCAGCCAGAAGACGATGGTTAGACTCCCACGAATCCGGTTATCA
CAAAAGCATGGGCAACCGGCAGATTCAAATGATCGCCATCGGCGGTTCAATAGGTACCGGCCTGTTCCTCGGCACCGGCG
GCCGGCTGGAACTGGCAGGGCCGGCGCTGGCGCTGGTGTATCTGGTCTGCGGTATCTTCTCTTTCTTCATTCTGCGGGCA
TTGGGCGAACTGGTTTTACACCGCCCTACCAGCGGCAGCTTTGTTTCTTACGCCCGCGAGTTCCTCGGTGAAAAAGCCTC
TTACGTCGCCGGCTGGATGTATTTCCTCAACTGGGCGATGACCGGTATCGTCGACATCACGGCAGTAGCGCTGTATATGC
ACTATTGGGGTACCTTTGCCGATGTGCCGCAGTGGTTGTTTGCCCTCTGCGCCCTCGGGGTGGTCGCCACCATGAACATG
ATCGGCGTGAAGTGGTTCGCCGAAATGGAGTTCTGGTTCGCCCTGATCAAAGTGGTCGCTATCGCGCTGTTCCTGGTGGT
CGGCGTGGTGTTACTCGGCACCGGCACCCCGGTGGCGGGCAACACCACCGGCCTGCACCTGATTACCGAAAACGGCGGCA
TGTTCCCGCATGGCCTGCTGCCTGCGTTGGTGCTGGTACAAGGGGTGATCTTCGCCTTTGCCGGGATTGAGCTGATCGGC
ACCGCCGCCGGCGAGTGCAAGGATCCGGCCAAAATGCTGCCGAAGGCTATCAACAGCGTTATTTGGCGCATCGGCCTGTT
CTACGTTGGCTCAGTGGTGCTGCTGGTGTTGCTGCTGCCGTGGAACGCCTACCAGGCGGGCCAAAGCCCGTTCGTCACCT
TCTTCAGCAAGCTGGGCGTGCCCTATATCGGCACCATCATGAACATCGTGGTGTTAACTGCCGCGCTCTCCAGCCTGAAC
TCGGGCCTGTACTCCACCGGCCGTATTCTGCGTTCGCTGTCGATGGGCGGCTCGGCGCCGAAATTTATGGCCAGGATGAG
CAGCCAGCAGGTGCCTTACGCCGGGATCCTGGTGACCTGCGGTATCTACGTGATCGGGGTGGTATTGAACTATCTGGTGC
CTTCACAGGTGTTTGAGATCGTGCTGAACATCGCTTCGTTGGGCATTATCAGCTCCTGGGCATTTATCATCGTCTGCCAG
ATGCGTCTGCGTAAGGCGGTGCGTGAAGGCCGTGCCAAGCCGGTTACCTTCAAGATGCCTGGCGCACCGGTCACCTCCTG
GCTGACGTTGGCGTTCCTGCTGGCGGTGGTGGTCATGATGGCGTTTGACTACCCGAACGGCACCTGGACCATCGCAACCA
TTCCTGTATTGGTCGTGCTGCTGGTGCTGGGCTGGTTTGGCCTGCGCAAGCGCGCGCAGGAAGTGAAACTGGAACAGCAG
GCGCACGAAGAAGCCCATCACTGA

Upstream 100 bases:

>100_bases
ATGATGCCATGACCTCATTCTCATCACGGTTGGTAGTAGCAATCGTTTGCTCCGAAACTGGGGCAGGATAATTTTACAGA
CGGGTAAAACAGGACGAACG

Downstream 100 bases:

>100_bases
GTTTTTAAACTGCCCCAACCGGGGTAATGCTTGTAAGTTAAGGTGATATGGTTCCCTCTCCTTTGGGAGAGGGTTAGGGT
GAGGGGATACATACCAACGC

Product: amino acid permease-associated protein

Products: Proton [Cytoplasm]; L-asparagine [Cytoplasm] [C]

Alternate protein names: L-asparagine transport protein [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MQSQKKSAHEQHAARRRWLDSHESGYHKSMGNRQIQMIAIGGSIGTGLFLGTGGRLELAGPALALVYLVCGIFSFFILRA
LGELVLHRPTSGSFVSYAREFLGEKASYVAGWMYFLNWAMTGIVDITAVALYMHYWGTFADVPQWLFALCALGVVATMNM
IGVKWFAEMEFWFALIKVVAIALFLVVGVVLLGTGTPVAGNTTGLHLITENGGMFPHGLLPALVLVQGVIFAFAGIELIG
TAAGECKDPAKMLPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGTIMNIVVLTAALSSLN
SGLYSTGRILRSLSMGGSAPKFMARMSSQQVPYAGILVTCGIYVIGVVLNYLVPSQVFEIVLNIASLGIISSWAFIIVCQ
MRLRKAVREGRAKPVTFKMPGAPVTSWLTLAFLLAVVVMMAFDYPNGTWTIATIPVLVVLLVLGWFGLRKRAQEVKLEQQ
AHEEAHH

Sequences:

>Translated_487_residues
MQSQKKSAHEQHAARRRWLDSHESGYHKSMGNRQIQMIAIGGSIGTGLFLGTGGRLELAGPALALVYLVCGIFSFFILRA
LGELVLHRPTSGSFVSYAREFLGEKASYVAGWMYFLNWAMTGIVDITAVALYMHYWGTFADVPQWLFALCALGVVATMNM
IGVKWFAEMEFWFALIKVVAIALFLVVGVVLLGTGTPVAGNTTGLHLITENGGMFPHGLLPALVLVQGVIFAFAGIELIG
TAAGECKDPAKMLPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGTIMNIVVLTAALSSLN
SGLYSTGRILRSLSMGGSAPKFMARMSSQQVPYAGILVTCGIYVIGVVLNYLVPSQVFEIVLNIASLGIISSWAFIIVCQ
MRLRKAVREGRAKPVTFKMPGAPVTSWLTLAFLLAVVVMMAFDYPNGTWTIATIPVLVVLLVLGWFGLRKRAQEVKLEQQ
AHEEAHH
>Mature_487_residues
MQSQKKSAHEQHAARRRWLDSHESGYHKSMGNRQIQMIAIGGSIGTGLFLGTGGRLELAGPALALVYLVCGIFSFFILRA
LGELVLHRPTSGSFVSYAREFLGEKASYVAGWMYFLNWAMTGIVDITAVALYMHYWGTFADVPQWLFALCALGVVATMNM
IGVKWFAEMEFWFALIKVVAIALFLVVGVVLLGTGTPVAGNTTGLHLITENGGMFPHGLLPALVLVQGVIFAFAGIELIG
TAAGECKDPAKMLPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGTIMNIVVLTAALSSLN
SGLYSTGRILRSLSMGGSAPKFMARMSSQQVPYAGILVTCGIYVIGVVLNYLVPSQVFEIVLNIASLGIISSWAFIIVCQ
MRLRKAVREGRAKPVTFKMPGAPVTSWLTLAFLLAVVVMMAFDYPNGTWTIATIPVLVVLLVLGWFGLRKRAQEVKLEQQ
AHEEAHH

Specific function: Unknown

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=429, Percent_Identity=21.6783216783217, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI258645169, Length=429, Percent_Identity=22.3776223776224, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI33286428, Length=387, Percent_Identity=26.3565891472868, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI258614003, Length=430, Percent_Identity=20.4651162790698, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI258614005, Length=430, Percent_Identity=20.4651162790698, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI87081915, Length=487, Percent_Identity=78.2340862422998, Blast_Score=786, Evalue=0.0,
Organism=Escherichia coli, GI1790653, Length=481, Percent_Identity=37.6299376299376, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI1786789, Length=452, Percent_Identity=37.1681415929204, Blast_Score=314, Evalue=1e-86,
Organism=Escherichia coli, GI1786302, Length=459, Percent_Identity=36.1655773420479, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI1786602, Length=457, Percent_Identity=35.8862144420131, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI48994972, Length=464, Percent_Identity=36.8534482758621, Blast_Score=296, Evalue=3e-81,
Organism=Escherichia coli, GI87081708, Length=433, Percent_Identity=34.8729792147806, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI1789017, Length=423, Percent_Identity=34.0425531914894, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1788480, Length=490, Percent_Identity=32.2448979591837, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI87081869, Length=271, Percent_Identity=22.8782287822878, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=455, Percent_Identity=24.6153846153846, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17532491, Length=439, Percent_Identity=21.8678815489749, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=419, Percent_Identity=22.673031026253, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=437, Percent_Identity=31.1212814645309, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324061, Length=449, Percent_Identity=29.1759465478842, Blast_Score=196, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6322892, Length=417, Percent_Identity=32.8537170263789, Blast_Score=192, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6324990, Length=441, Percent_Identity=29.4784580498866, Blast_Score=175, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324924, Length=489, Percent_Identity=28.6298568507157, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324553, Length=425, Percent_Identity=29.8823529411765, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6321629, Length=405, Percent_Identity=27.4074074074074, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324059, Length=456, Percent_Identity=29.8245614035088, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322967, Length=413, Percent_Identity=28.5714285714286, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6321053, Length=432, Percent_Identity=26.3888888888889, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319824, Length=403, Percent_Identity=28.287841191067, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6320251, Length=423, Percent_Identity=28.1323877068558, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319543, Length=444, Percent_Identity=28.8288288288288, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6320717, Length=426, Percent_Identity=27.4647887323944, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319542, Length=429, Percent_Identity=26.8065268065268, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6324981, Length=403, Percent_Identity=28.7841191066998, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319608, Length=481, Percent_Identity=25.7796257796258, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6320364, Length=506, Percent_Identity=21.3438735177866, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221512776, Length=429, Percent_Identity=22.3776223776224, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24666159, Length=425, Percent_Identity=22.5882352941176, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24668806, Length=434, Percent_Identity=23.0414746543779, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356285, Length=434, Percent_Identity=23.0414746543779, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24668802, Length=434, Percent_Identity=23.0414746543779, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52986; Mature: 52986

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSQKKSAHEQHAARRRWLDSHESGYHKSMGNRQIQMIAIGGSIGTGLFLGTGGRLELAG
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEECCCCCCCEEECCCCCEEECC
PALALVYLVCGIFSFFILRALGELVLHRPTSGSFVSYAREFLGEKASYVAGWMYFLNWAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TGIVDITAVALYMHYWGTFADVPQWLFALCALGVVATMNMIGVKWFAEMEFWFALIKVVA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALFLVVGVVLLGTGTPVAGNTTGLHLITENGGMFPHGLLPALVLVQGVIFAFAGIELIG
HHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TAAGECKDPAKMLPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCC
PYIGTIMNIVVLTAALSSLNSGLYSTGRILRSLSMGGSAPKFMARMSSQQVPYAGILVTC
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHH
GIYVIGVVLNYLVPSQVFEIVLNIASLGIISSWAFIIVCQMRLRKAVREGRAKPVTFKMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
GAPVTSWLTLAFLLAVVVMMAFDYPNGTWTIATIPVLVVLLVLGWFGLRKRAQEVKLEQQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHEEAHH
HHHHCCC
>Mature Secondary Structure
MQSQKKSAHEQHAARRRWLDSHESGYHKSMGNRQIQMIAIGGSIGTGLFLGTGGRLELAG
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEECCCCCCCEEECCCCCEEECC
PALALVYLVCGIFSFFILRALGELVLHRPTSGSFVSYAREFLGEKASYVAGWMYFLNWAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TGIVDITAVALYMHYWGTFADVPQWLFALCALGVVATMNMIGVKWFAEMEFWFALIKVVA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALFLVVGVVLLGTGTPVAGNTTGLHLITENGGMFPHGLLPALVLVQGVIFAFAGIELIG
HHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TAAGECKDPAKMLPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCC
PYIGTIMNIVVLTAALSSLNSGLYSTGRILRSLSMGGSAPKFMARMSSQQVPYAGILVTC
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHH
GIYVIGVVLNYLVPSQVFEIVLNIASLGIISSWAFIIVCQMRLRKAVREGRAKPVTFKMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
GAPVTSWLTLAFLLAVVVMMAFDYPNGTWTIATIPVLVVLLVLGWFGLRKRAQEVKLEQQ
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHEEAHH
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-asparagine [Periplasm]; Proton [Periplasm] [C]

Specific reaction: L-asparagine [Periplasm] + Proton [Periplasm] = Proton [Cytoplasm] + L-asparagine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]