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The map label for this gene is modF [H]

Identifier: 157369538

GI number: 157369538

Start: 1424134

End: 1425606

Strand: Reverse

Name: modF [H]

Synonym: Spro_1295

Alternate gene names: 157369538

Gene position: 1425606-1424134 (Counterclockwise)

Preceding gene: 157369539

Following gene: 157369537

Centisome position: 26.16

GC content: 59.33

Gene sequence:

>1473_bases
ATGTCGTCGTTGCACATTTCGCAAGGTTCATTCCGCTTAAGCGATACCCGCACCCTGACGCTGGATGCGCTGGATATTCA
GGCCGGCGACAGCTGGGCCTTTGTCGGCGCCAACGGCAGCGGTAAATCTGCGCTGGCTCGCGCACTGGCCAATGAGCTGG
TGTTATTGAGCGGCGAACGGCGCAGTGATTTCCGCCATGCGGTACGTATCTCTTTCGAACAGTTGCAAAAACTGGTCAGC
GACGAATGGCAACGCAACAATACCGACCTGCTTAGCCCTGGCGAAGAAGATACCGGCCGCACCGTGGCGGAAATCATTCA
GGAAGAGCTCAAGGACCCAGCCCGCTGCGCCCAATTGGCCGAACAGTTCGGCATCACCCCGCTGTTGTCACGTCGCTTCA
AATATCTTTCTACCGGCGAAACACGCAAAACCTTGCTGTGTCGGGCGCTGATGCCGCAACCCGACCTGCTGATCCTCGAT
GAGCCTTTTGACGGGCTGGATGTCAATTCACGCGCCCAATTGGCTGCGCTGCTGAGCGACCTTTCAGGGCATGGCTATAC
CCTGGTGCTGGTACTCAACCGTTTTGACGAGGTACCGGACTTTATCCGTCAGGTGGGCGTATTGGCGGACTGTACTTTGG
CCAGTCAGGGAACGCGGCAGCAGGTGATGGCCGACGCACTGGTCGCTCAACTGGCCCACAGTGAAAACCTGGATGGCCTG
GCGCTGCCGGAAACCGAAGATCCCGCGCAAAAAACCACGCTGCCGGCAGACCAGCCGCTCATCATCCTGCGTGGTGGCGT
AGTCAGTTATAACGATCAACCGATCCTCAATCATCTCGACTGGCAGGTTAACCCCGGCGAGCACTGGCAGATCGTCGGCC
CGAACGGCGCCGGTAAATCCACCCTGCTCAGCCTGATCACCGGCGATCATCCTCAAGGGTACAGTAACGATCTCACCCTG
TTTGGCCGCCGTCGCGGCAGCGGGGAAACCATCTGGGATATCAAACGCCATATCGGCTACGTCAGCAGCAGCCTGCACCT
GGACTACCGCGTCAGTGCCAGCGTGCGTACCGTGATCCTGTCCGGTTTCTTCGATTCGATTGGCATTTATCAGGCGGTGT
CCGATCGCCAGCGGCAATTGGCCGACCAATGGCTGGCACTGCTGGGGCTGGGTGGCTCAAAGGGAGAAGCGCCGTTCCAT
AGCCTGTCCTGGGGGCAGCAGCGGTTGGCATTGATTGCCCGCGCACTGGTCAAGCACCCGGCGCTGCTGATCCTCGACGA
ACCGCTACAGGGGCTGGATCCGCTCAATCGCCAGCTGGTACGCCGTTTTGTCGACGTGTTGATCGGTCAGGGCGCAACCC
AGCTGTTGTTTGTTTCGCACCATGCAGAGGACGCGCCACAGAGTATTACCCACCGCCTGAGCTTTGTGCCTGACGGCGAC
GGCTATCGCTACCAGCACGATACGCTGAACTGA

Upstream 100 bases:

>100_bases
GTTGTGTTAAACGCAACGTAACGTTGCATTTTTGCCGATTGACATCACCCTGCAATGCGCCTATTTCTAAACAAAATAAT
TGCATAAAAAGGAACAGGTG

Downstream 100 bases:

>100_bases
AAAATCCGGATGGGGGCTTTGCCACTCATCCGATGACATATCCGGCAACACTTCCCCGGTAACACATCACATTTGGCCTT
TTATCATAAGGGGAAAGGAT

Product: putative molybdenum transport ATP-binding protein ModF

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSSLHISQGSFRLSDTRTLTLDALDIQAGDSWAFVGANGSGKSALARALANELVLLSGERRSDFRHAVRISFEQLQKLVS
DEWQRNNTDLLSPGEEDTGRTVAEIIQEELKDPARCAQLAEQFGITPLLSRRFKYLSTGETRKTLLCRALMPQPDLLILD
EPFDGLDVNSRAQLAALLSDLSGHGYTLVLVLNRFDEVPDFIRQVGVLADCTLASQGTRQQVMADALVAQLAHSENLDGL
ALPETEDPAQKTTLPADQPLIILRGGVVSYNDQPILNHLDWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKRHIGYVSSSLHLDYRVSASVRTVILSGFFDSIGIYQAVSDRQRQLADQWLALLGLGGSKGEAPFH
SLSWGQQRLALIARALVKHPALLILDEPLQGLDPLNRQLVRRFVDVLIGQGATQLLFVSHHAEDAPQSITHRLSFVPDGD
GYRYQHDTLN

Sequences:

>Translated_490_residues
MSSLHISQGSFRLSDTRTLTLDALDIQAGDSWAFVGANGSGKSALARALANELVLLSGERRSDFRHAVRISFEQLQKLVS
DEWQRNNTDLLSPGEEDTGRTVAEIIQEELKDPARCAQLAEQFGITPLLSRRFKYLSTGETRKTLLCRALMPQPDLLILD
EPFDGLDVNSRAQLAALLSDLSGHGYTLVLVLNRFDEVPDFIRQVGVLADCTLASQGTRQQVMADALVAQLAHSENLDGL
ALPETEDPAQKTTLPADQPLIILRGGVVSYNDQPILNHLDWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKRHIGYVSSSLHLDYRVSASVRTVILSGFFDSIGIYQAVSDRQRQLADQWLALLGLGGSKGEAPFH
SLSWGQQRLALIARALVKHPALLILDEPLQGLDPLNRQLVRRFVDVLIGQGATQLLFVSHHAEDAPQSITHRLSFVPDGD
GYRYQHDTLN
>Mature_489_residues
SSLHISQGSFRLSDTRTLTLDALDIQAGDSWAFVGANGSGKSALARALANELVLLSGERRSDFRHAVRISFEQLQKLVSD
EWQRNNTDLLSPGEEDTGRTVAEIIQEELKDPARCAQLAEQFGITPLLSRRFKYLSTGETRKTLLCRALMPQPDLLILDE
PFDGLDVNSRAQLAALLSDLSGHGYTLVLVLNRFDEVPDFIRQVGVLADCTLASQGTRQQVMADALVAQLAHSENLDGLA
LPETEDPAQKTTLPADQPLIILRGGVVSYNDQPILNHLDWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLF
GRRRGSGETIWDIKRHIGYVSSSLHLDYRVSASVRTVILSGFFDSIGIYQAVSDRQRQLADQWLALLGLGGSKGEAPFHS
LSWGQQRLALIARALVKHPALLILDEPLQGLDPLNRQLVRRFVDVLIGQGATQLLFVSHHAEDAPQSITHRLSFVPDGDG
YRYQHDTLN

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Escherichia coli, GI1786975, Length=484, Percent_Identity=76.8595041322314, Blast_Score=770, Evalue=0.0,
Organism=Escherichia coli, GI48995001, Length=461, Percent_Identity=24.5119305856833, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI48994943, Length=480, Percent_Identity=27.0833333333333, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788506, Length=499, Percent_Identity=26.8537074148297, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788897, Length=478, Percent_Identity=22.3849372384937, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788225, Length=221, Percent_Identity=28.9592760180996, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI145693107, Length=534, Percent_Identity=22.4719101123595, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786319, Length=190, Percent_Identity=30, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790190, Length=471, Percent_Identity=23.3545647558386, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787029, Length=206, Percent_Identity=30.0970873786408, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790544, Length=195, Percent_Identity=31.2820512820513, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787792, Length=451, Percent_Identity=23.2815964523282, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790739, Length=218, Percent_Identity=27.9816513761468, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786563, Length=224, Percent_Identity=29.9107142857143, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081782, Length=291, Percent_Identity=25.4295532646048, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788165, Length=206, Percent_Identity=30.5825242718447, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789593, Length=220, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787758, Length=265, Percent_Identity=28.6792452830189, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789864, Length=234, Percent_Identity=26.4957264957265, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790525, Length=470, Percent_Identity=20.8510638297872, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788450, Length=177, Percent_Identity=31.0734463276836, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787112, Length=213, Percent_Identity=26.7605633802817, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786803, Length=260, Percent_Identity=23.4615384615385, Blast_Score=62, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320266, Length=393, Percent_Identity=28.498727735369, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24650855, Length=202, Percent_Identity=31.1881188118812, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650853, Length=202, Percent_Identity=31.1881188118812, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281362751, Length=202, Percent_Identity=31.1881188118812, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85725262, Length=212, Percent_Identity=30.188679245283, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 53962; Mature: 53830

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLHISQGSFRLSDTRTLTLDALDIQAGDSWAFVGANGSGKSALARALANELVLLSGER
CCCEECCCCCEEECCCEEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHCEEEEECCC
RSDFRHAVRISFEQLQKLVSDEWQRNNTDLLSPGEEDTGRTVAEIIQEELKDPARCAQLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
EQFGITPLLSRRFKYLSTGETRKTLLCRALMPQPDLLILDEPFDGLDVNSRAQLAALLSD
HHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHH
LSGHGYTLVLVLNRFDEVPDFIRQVGVLADCTLASQGTRQQVMADALVAQLAHSENLDGL
HCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
ALPETEDPAQKTTLPADQPLIILRGGVVSYNDQPILNHLDWQVNPGEHWQIVGPNGAGKS
CCCCCCCCHHHCCCCCCCCEEEEECCEEEECCCCHHHCCCCEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKRHIGYVSSSLHLDYRVSASVRTVIL
HHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEECCHHHHHHH
SGFFDSIGIYQAVSDRQRQLADQWLALLGLGGSKGEAPFHSLSWGQQRLALIARALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
ALLILDEPLQGLDPLNRQLVRRFVDVLIGQGATQLLFVSHHAEDAPQSITHRLSFVPDGD
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCC
GYRYQHDTLN
CCEECCCCCC
>Mature Secondary Structure 
SSLHISQGSFRLSDTRTLTLDALDIQAGDSWAFVGANGSGKSALARALANELVLLSGER
CCEECCCCCEEECCCEEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHCEEEEECCC
RSDFRHAVRISFEQLQKLVSDEWQRNNTDLLSPGEEDTGRTVAEIIQEELKDPARCAQLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
EQFGITPLLSRRFKYLSTGETRKTLLCRALMPQPDLLILDEPFDGLDVNSRAQLAALLSD
HHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHH
LSGHGYTLVLVLNRFDEVPDFIRQVGVLADCTLASQGTRQQVMADALVAQLAHSENLDGL
HCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
ALPETEDPAQKTTLPADQPLIILRGGVVSYNDQPILNHLDWQVNPGEHWQIVGPNGAGKS
CCCCCCCCHHHCCCCCCCCEEEEECCEEEECCCCHHHCCCCEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKRHIGYVSSSLHLDYRVSASVRTVIL
HHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEECCHHHHHHH
SGFFDSIGIYQAVSDRQRQLADQWLALLGLGGSKGEAPFHSLSWGQQRLALIARALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
ALLILDEPLQGLDPLNRQLVRRFVDVLIGQGATQLLFVSHHAEDAPQSITHRLSFVPDGD
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCC
GYRYQHDTLN
CCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]