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The map label for this gene is cpdP [H]

Identifier: 157369496

GI number: 157369496

Start: 1379311

End: 1380291

Strand: Direct

Name: cpdP [H]

Synonym: Spro_1253

Alternate gene names: 157369496

Gene position: 1379311-1380291 (Clockwise)

Preceding gene: 157369495

Following gene: 157369497

Centisome position: 25.31

GC content: 55.76

Gene sequence:

>981_bases
ATGATGAAAAAGGTGCTGGCCCTGTGCCTGAGCGGCTATTGCGCCTTGGCGCAGGCCGGCTTTGACGTGGTGGCGCTGGG
CGTGGACGGCGGCGTGGGGGGCGGCAATCTGACCTCCTACCTGATCCGCAGCGACAATCAGACGCAGTATCTGGCGCTGG
ATGCCGGCTCACTGCTACCGGGCATCGCCAAAGGGCTGGAAAAGGGCAGTTTCCCGCAGGTCACCCCTGAACTGGCTGCG
CCTTATACCCCGCAGGGCTATATCTTCCGCCAGTTAATCGGCGCTTACTTTATCAGCCATGGTCATCTGGACCACGTGGC
CGGGCTGATTATCGGTTCGCCGGAAGACAGTAAAAAGAATATCTATGCCCAGGTCGATACCATTTTGACCCTGCGTAATC
ATTATTTTAACTGGAAGGCCTGGCCTAACTTCACTGATTCCGGCAACGGTTCGCGACTGGGGACTTACCGATTGCAAACG
GTACGGCCACAGCAGCGCGTGACTCTGGGCATGACTGGTTTGAGTGGCGTGATGTATCCGCTCAGTCATGACCGCTACCC
TTCTTCGATGTTGCTGGTGTCCGATCGCAGCGGCTCTTTCGCCTATTTTGGTGATACCGGAGCGGATGCACTTGAGCAGT
CGCGCAATCTCGATAGCGCCTGGCGTGCGCTGGGGCCGTTGATTGAGCAGAAAAAGTTGAAAGGGATGATTATCGAAACC
TCCTATCCCAATGAGGTGGAAGATAAAAACCTGTATGGCCACCTGACGCCGGCGTGGCTGCAAAAAGAGTTGAAGAATCT
GACTCAGTACAGCGGCGGCGAAGGTTCGCTGAAAGATTTTCCGGTGGTGATCAGCCATATCAAGCCCAGCCTGAAGCAGG
GCGAAGACGTGCGTGCGACCATCAAACAGCAGTTGGAACAGGGTAACAGCCTGGGCGTAAAATATATCCTGATGGAACAG
GGCGACCGGCAGACATTTTGA

Upstream 100 bases:

>100_bases
CTGCCGATCGTCGACCACAAACAGGCGCGGCTGGAGACGCTGGCGGCCTTTGAAGCGGCGAAGCGCGGGGAATATTAAGG
CAACAGCAAGGAGCGAAATA

Downstream 100 bases:

>100_bases
ATTAAAGAGAGAACTCTATGCGTAACCTCGATCTGGAACAGTTGATCAACACAGAACTGAACACCGCCGCGTTTCAGGAT
TACGGGCCGAATGGCCTGCA

Product: cyclic-AMP phosphodiesterase

Products: NA

Alternate protein names: 3':5'-CNP; PDEase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MMKKVLALCLSGYCALAQAGFDVVALGVDGGVGGGNLTSYLIRSDNQTQYLALDAGSLLPGIAKGLEKGSFPQVTPELAA
PYTPQGYIFRQLIGAYFISHGHLDHVAGLIIGSPEDSKKNIYAQVDTILTLRNHYFNWKAWPNFTDSGNGSRLGTYRLQT
VRPQQRVTLGMTGLSGVMYPLSHDRYPSSMLLVSDRSGSFAYFGDTGADALEQSRNLDSAWRALGPLIEQKKLKGMIIET
SYPNEVEDKNLYGHLTPAWLQKELKNLTQYSGGEGSLKDFPVVISHIKPSLKQGEDVRATIKQQLEQGNSLGVKYILMEQ
GDRQTF

Sequences:

>Translated_326_residues
MMKKVLALCLSGYCALAQAGFDVVALGVDGGVGGGNLTSYLIRSDNQTQYLALDAGSLLPGIAKGLEKGSFPQVTPELAA
PYTPQGYIFRQLIGAYFISHGHLDHVAGLIIGSPEDSKKNIYAQVDTILTLRNHYFNWKAWPNFTDSGNGSRLGTYRLQT
VRPQQRVTLGMTGLSGVMYPLSHDRYPSSMLLVSDRSGSFAYFGDTGADALEQSRNLDSAWRALGPLIEQKKLKGMIIET
SYPNEVEDKNLYGHLTPAWLQKELKNLTQYSGGEGSLKDFPVVISHIKPSLKQGEDVRATIKQQLEQGNSLGVKYILMEQ
GDRQTF
>Mature_326_residues
MMKKVLALCLSGYCALAQAGFDVVALGVDGGVGGGNLTSYLIRSDNQTQYLALDAGSLLPGIAKGLEKGSFPQVTPELAA
PYTPQGYIFRQLIGAYFISHGHLDHVAGLIIGSPEDSKKNIYAQVDTILTLRNHYFNWKAWPNFTDSGNGSRLGTYRLQT
VRPQQRVTLGMTGLSGVMYPLSHDRYPSSMLLVSDRSGSFAYFGDTGADALEQSRNLDSAWRALGPLIEQKKLKGMIIET
SYPNEVEDKNLYGHLTPAWLQKELKNLTQYSGGEGSLKDFPVVISHIKPSLKQGEDVRATIKQQLEQGNSLGVKYILMEQ
GDRQTF

Specific function: Unknown

COG id: COG5212

COG function: function code T; Low-affinity cAMP phosphodiesterase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cAMP phosphodiesterase class-II family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321189, Length=314, Percent_Identity=26.1146496815287, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000396 [H]

Pfam domain/function: PF02112 PDEase_II [H]

EC number: =3.1.4.17 [H]

Molecular weight: Translated: 35756; Mature: 35756

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS00607 PDEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKVLALCLSGYCALAQAGFDVVALGVDGGVGGGNLTSYLIRSDNQTQYLALDAGSLLP
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHEEEEECCCCCEEEEEECCHHHH
GIAKGLEKGSFPQVTPELAAPYTPQGYIFRQLIGAYFISHGHLDHVAGLIIGSPEDSKKN
HHHHHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHEEEEECCCCCCCH
IYAQVDTILTLRNHYFNWKAWPNFTDSGNGSRLGTYRLQTVRPQQRVTLGMTGLSGVMYP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHEEEEECCCCCEECC
LSHDRYPSSMLLVSDRSGSFAYFGDTGADALEQSRNLDSAWRALGPLIEQKKLKGMIIET
CCCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEC
SYPNEVEDKNLYGHLTPAWLQKELKNLTQYSGGEGSLKDFPVVISHIKPSLKQGEDVRAT
CCCCCCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCCHHHHH
IKQQLEQGNSLGVKYILMEQGDRQTF
HHHHHHCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MMKKVLALCLSGYCALAQAGFDVVALGVDGGVGGGNLTSYLIRSDNQTQYLALDAGSLLP
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHEEEEECCCCCEEEEEECCHHHH
GIAKGLEKGSFPQVTPELAAPYTPQGYIFRQLIGAYFISHGHLDHVAGLIIGSPEDSKKN
HHHHHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHEEEEECCCCCCCH
IYAQVDTILTLRNHYFNWKAWPNFTDSGNGSRLGTYRLQTVRPQQRVTLGMTGLSGVMYP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHEEEEECCCCCEECC
LSHDRYPSSMLLVSDRSGSFAYFGDTGADALEQSRNLDSAWRALGPLIEQKKLKGMIIET
CCCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEC
SYPNEVEDKNLYGHLTPAWLQKELKNLTQYSGGEGSLKDFPVVISHIKPSLKQGEDVRAT
CCCCCCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHCCCHHHHH
IKQQLEQGNSLGVKYILMEQGDRQTF
HHHHHHCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]