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The map label for this gene is uidR [H]

Identifier: 157369434

GI number: 157369434

Start: 1308672

End: 1309268

Strand: Reverse

Name: uidR [H]

Synonym: Spro_1191

Alternate gene names: 157369434

Gene position: 1309268-1308672 (Counterclockwise)

Preceding gene: 157369435

Following gene: 157369433

Centisome position: 24.03

GC content: 55.28

Gene sequence:

>597_bases
ATGATATCCACCAGCGACAGCAGGCAGGCCAAAGCACAGGCCCGCCGCGATCAGATTGTCGACGCCGCAAAACTCTGTTT
TCGTCAGCACGGTTTTCACGCCGCCAGCATGGCGGAAATCGCGCAGGGTTCCCAGCTTAGCGTCGGTCAGATCTACCGCT
ACTTCGACAATAAAGATGCGATCATCGAAGAGATCGTTAACCGCATCATCGCCAGTAAAATGCGGCGGCTGGAAGATCTT
GGCGATCATATCAACCTGATCGCCGGTACCCTGGCGGCGCGCGCCCTGTTTCAACAGCCGGGTGAAAGCGAAACCGACCA
TATGCTGATGCTGGAGGTCACCGCCGAGGCCACACGTAACCCGATAGTGGCCAAAATGCTCAGCGATGCCGAAACGCGGT
TATTCCACCATGTTTGCCAAAACCTGCGGCGGATCTACCCTCACTTCAGCGAGCAGGAAATCGCCGCCAGAGTAGAGTTT
ATCGCCGTATTAAGCGAAGGCACCGGTTACCGCATACTGACCACACAAAAAGCCGACGTCAGCCTGCTGAACGGCCTATA
CCAACAAGCTATCTCTCACCTGTTCAGGAAACCTTAA

Upstream 100 bases:

>100_bases
ACCGTTGCGCTCTTGCCAATTGCCATTGTTGCATTACAATTGAGAATGAACGTTCGCACCCAGAAAGCGAACCGCATTTC
ACTTGGCAAAGGATCGGGAC

Downstream 100 bases:

>100_bases
TCCCTATGACCAGACAACTTGCCAGACAACGTCTGGTATACGCGCTCGTGCTTGGCCTGCTAGCCTCACTGGGGCCGCTG
TGCATCGACCTCTACCTGCC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: Uid operon repressor [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MISTSDSRQAKAQARRDQIVDAAKLCFRQHGFHAASMAEIAQGSQLSVGQIYRYFDNKDAIIEEIVNRIIASKMRRLEDL
GDHINLIAGTLAARALFQQPGESETDHMLMLEVTAEATRNPIVAKMLSDAETRLFHHVCQNLRRIYPHFSEQEIAARVEF
IAVLSEGTGYRILTTQKADVSLLNGLYQQAISHLFRKP

Sequences:

>Translated_198_residues
MISTSDSRQAKAQARRDQIVDAAKLCFRQHGFHAASMAEIAQGSQLSVGQIYRYFDNKDAIIEEIVNRIIASKMRRLEDL
GDHINLIAGTLAARALFQQPGESETDHMLMLEVTAEATRNPIVAKMLSDAETRLFHHVCQNLRRIYPHFSEQEIAARVEF
IAVLSEGTGYRILTTQKADVSLLNGLYQQAISHLFRKP
>Mature_198_residues
MISTSDSRQAKAQARRDQIVDAAKLCFRQHGFHAASMAEIAQGSQLSVGQIYRYFDNKDAIIEEIVNRIIASKMRRLEDL
GDHINLIAGTLAARALFQQPGESETDHMLMLEVTAEATRNPIVAKMLSDAETRLFHHVCQNLRRIYPHFSEQEIAARVEF
IAVLSEGTGYRILTTQKADVSLLNGLYQQAISHLFRKP

Specific function: Repressor for the uidRABC (gusRABC) operon [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787904, Length=138, Percent_Identity=29.7101449275362, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22309; Mature: 22309

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTSDSRQAKAQARRDQIVDAAKLCFRQHGFHAASMAEIAQGSQLSVGQIYRYFDNKDA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHCCCHH
IIEEIVNRIIASKMRRLEDLGDHINLIAGTLAARALFQQPGESETDHMLMLEVTAEATRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHCC
PIVAKMLSDAETRLFHHVCQNLRRIYPHFSEQEIAARVEFIAVLSEGTGYRILTTQKADV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
SLLNGLYQQAISHLFRKP
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISTSDSRQAKAQARRDQIVDAAKLCFRQHGFHAASMAEIAQGSQLSVGQIYRYFDNKDA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHCCCHH
IIEEIVNRIIASKMRRLEDLGDHINLIAGTLAARALFQQPGESETDHMLMLEVTAEATRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHCC
PIVAKMLSDAETRLFHHVCQNLRRIYPHFSEQEIAARVEFIAVLSEGTGYRILTTQKADV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
SLLNGLYQQAISHLFRKP
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]