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The map label for this gene is dctB [H]

Identifier: 157369309

GI number: 157369309

Start: 1172913

End: 1174670

Strand: Reverse

Name: dctB [H]

Synonym: Spro_1066

Alternate gene names: 157369309

Gene position: 1174670-1172913 (Counterclockwise)

Preceding gene: 157369313

Following gene: 157369308

Centisome position: 21.56

GC content: 59.61

Gene sequence:

>1758_bases
GTGAAAAGAGCAGCGCTAATCTTGTTGCTGGGGGGTTGGTTAAACGTTGCCTGGGCGGGGCAATGGACCATCGCGGTGCT
GGCGCTGCGCGGCGACGCGCATGCACTGGCCCAGTGGCAACCCTTGGTCGATCACCTTAATCGCCAGTTTCCCGGCGATC
ACTTCCAACTGTCGCCGCTAAGCCTGGCCGGTATGGATGAGGCGGTCCGTAATGAACGCGTGGACTTTTTGCTCACCAAC
CCGGCGCAATATGTCCAGTTGGATAACCGCTACCCGCTGCGCTGGCTGGTTTCGCTGCGTTCTTCCCAACAGCCGCAGCA
GGCCTCAGGCAACGTGGTCGGCAGCGCCATACTGGTGCGCCACGACAGCCCAACCACTACGGCCAGCCAGTTAGTTGGTA
AAAAGGTCGGTGCCGTCGCCGCGGACGCTTTTGGCGGCTACCTGCTGGGATATAAAGAACTGCTTGGCGCGGGCCTTGAC
CCGGAGAAAGACTTGCAACTGCATTTCAGCGGTTACCCGGCGGATGCTCTGCTTTATCAGCTGCGCGATCGGGCGCTGGA
TGCGGTGATTGTGCCGGTTTGCCTGCTGGAAAAAATGCAGGCGGAAGGGTTGCTGCAGGCCAGTGATTACCGCGCCCTGT
TGGCAAAACACAGTGGCCAGCCCTGCCTGACCAGCACCGAGCTGTATCCCAACTGGTCATTTGCCGCCCTGAACCACGTC
CCGGATCGGCTGGCAGATGAGTTAACCCGCCAGTTACTGCAGATGAACGCTCCCGGCCTGCCGGTTTGGGGTGCCCCGGC
GTCATCCCGCCAGGTTAATCAGCTACTGCGCGATTTGAATATCCACCCAAGCCAACGCTCACTCTGGCAGGAGGTGACCC
TTTGGGCACAGCAACACCTGCTGTTGCTCGGAGGCATCTTCGGGGGGATGCTGTTGCTCGGCGCTAACCACCTGTGGATC
GGCCATCTGGTGCGCCGCCGCGGACGCCAACTCGAACAAATGCATCAGACACTGCGCGCCAGAGAAACTGCTCTGGCTCA
GGCACAACGCCTCAGCACTCTGGGGGAGATGGCGTCCGGCTTTGCTCATGAGCTTAACCAGCCGCTGGCGGCGATCCGGC
ACTATGCGGAGGGCTGCCGTATTCGTCTTGAGCGCAGCGATCGACAGCACGAGTTGCTGCCGATCCTCGAGCAGATTGGC
CAGCAGGCGCAGCGTGGTGCGGAAAGCATTGTCAATTTGCGACGCTGGGCCAGCAAAACGCCGCACCATGAAAGCACACG
CCCCCTGCTGTTGCGTCCGCTGGTGGAACACCTGATTAAACTGATGCAAATAGAACAACAGTATCCGCTGTGCCGCATAA
CCCTGGCCATCCCGGCTCAAAGCCAGTTGTATAGCCAGACGACGTTGTTGGAGCAAGTGCTCACTAATTTGCTGAGTAAC
AGCCTGCAAGCAGGTGCCCAACAAATCACTCTGCGGCTGGAAGTCGACCAACATCAGCAACGGTTGATCGTTGAGGACGA
CGGCGGCGGCCTGAACGCCGAGCAGTTGACGCTGCCGTTCGTCCCGTTTCGCAGCAGCAAACCGGAAGGCCTCGGCTTGG
GGCTGGTGATCTGCCAGCGGTTGCTGAAGCACCAGGGCGGCGATCTGACACTGGAAAACTATTTTTCCGCTTCTCAACAG
CAAGGGTTGCGCGTGACCCTGTACTTCCCCGTGATCCAACAGGAAACCTGCCATGGCGTTAATACATCTGGTCGATGA

Upstream 100 bases:

>100_bases
CAGCGACCGACCGCCAATATTGTGGTTTACCACATTCCCCACGGCGGCTTGATCCAGGACAATTCAACCCGGTGATACGG
ATCATAAAAGTGGAGAAGAG

Downstream 100 bases:

>100_bases
CGATTTAGCCGTTACCGACGCCTGCCGCTTTTTACTCGAGGGGCTGAACTATCGGGTGCAGATCTGGCACGACAGCCAAA
AGTTCGTCGACCAGGTCAGT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MKRAALILLLGGWLNVAWAGQWTIAVLALRGDAHALAQWQPLVDHLNRQFPGDHFQLSPLSLAGMDEAVRNERVDFLLTN
PAQYVQLDNRYPLRWLVSLRSSQQPQQASGNVVGSAILVRHDSPTTTASQLVGKKVGAVAADAFGGYLLGYKELLGAGLD
PEKDLQLHFSGYPADALLYQLRDRALDAVIVPVCLLEKMQAEGLLQASDYRALLAKHSGQPCLTSTELYPNWSFAALNHV
PDRLADELTRQLLQMNAPGLPVWGAPASSRQVNQLLRDLNIHPSQRSLWQEVTLWAQQHLLLLGGIFGGMLLLGANHLWI
GHLVRRRGRQLEQMHQTLRARETALAQAQRLSTLGEMASGFAHELNQPLAAIRHYAEGCRIRLERSDRQHELLPILEQIG
QQAQRGAESIVNLRRWASKTPHHESTRPLLLRPLVEHLIKLMQIEQQYPLCRITLAIPAQSQLYSQTTLLEQVLTNLLSN
SLQAGAQQITLRLEVDQHQQRLIVEDDGGGLNAEQLTLPFVPFRSSKPEGLGLGLVICQRLLKHQGGDLTLENYFSASQQ
QGLRVTLYFPVIQQETCHGVNTSGR

Sequences:

>Translated_585_residues
MKRAALILLLGGWLNVAWAGQWTIAVLALRGDAHALAQWQPLVDHLNRQFPGDHFQLSPLSLAGMDEAVRNERVDFLLTN
PAQYVQLDNRYPLRWLVSLRSSQQPQQASGNVVGSAILVRHDSPTTTASQLVGKKVGAVAADAFGGYLLGYKELLGAGLD
PEKDLQLHFSGYPADALLYQLRDRALDAVIVPVCLLEKMQAEGLLQASDYRALLAKHSGQPCLTSTELYPNWSFAALNHV
PDRLADELTRQLLQMNAPGLPVWGAPASSRQVNQLLRDLNIHPSQRSLWQEVTLWAQQHLLLLGGIFGGMLLLGANHLWI
GHLVRRRGRQLEQMHQTLRARETALAQAQRLSTLGEMASGFAHELNQPLAAIRHYAEGCRIRLERSDRQHELLPILEQIG
QQAQRGAESIVNLRRWASKTPHHESTRPLLLRPLVEHLIKLMQIEQQYPLCRITLAIPAQSQLYSQTTLLEQVLTNLLSN
SLQAGAQQITLRLEVDQHQQRLIVEDDGGGLNAEQLTLPFVPFRSSKPEGLGLGLVICQRLLKHQGGDLTLENYFSASQQ
QGLRVTLYFPVIQQETCHGVNTSGR
>Mature_585_residues
MKRAALILLLGGWLNVAWAGQWTIAVLALRGDAHALAQWQPLVDHLNRQFPGDHFQLSPLSLAGMDEAVRNERVDFLLTN
PAQYVQLDNRYPLRWLVSLRSSQQPQQASGNVVGSAILVRHDSPTTTASQLVGKKVGAVAADAFGGYLLGYKELLGAGLD
PEKDLQLHFSGYPADALLYQLRDRALDAVIVPVCLLEKMQAEGLLQASDYRALLAKHSGQPCLTSTELYPNWSFAALNHV
PDRLADELTRQLLQMNAPGLPVWGAPASSRQVNQLLRDLNIHPSQRSLWQEVTLWAQQHLLLLGGIFGGMLLLGANHLWI
GHLVRRRGRQLEQMHQTLRARETALAQAQRLSTLGEMASGFAHELNQPLAAIRHYAEGCRIRLERSDRQHELLPILEQIG
QQAQRGAESIVNLRRWASKTPHHESTRPLLLRPLVEHLIKLMQIEQQYPLCRITLAIPAQSQLYSQTTLLEQVLTNLLSN
SLQAGAQQITLRLEVDQHQQRLIVEDDGGGLNAEQLTLPFVPFRSSKPEGLGLGLVICQRLLKHQGGDLTLENYFSASQQ
QGLRVTLYFPVIQQETCHGVNTSGR

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=209, Percent_Identity=32.0574162679426, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=27.1604938271605, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65182; Mature: 65182

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAALILLLGGWLNVAWAGQWTIAVLALRGDAHALAQWQPLVDHLNRQFPGDHFQLSPL
CCCEEEEEEECCCCCEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEECCC
SLAGMDEAVRNERVDFLLTNPAQYVQLDNRYPLRWLVSLRSSQQPQQASGNVVGSAILVR
HHCCCHHHHHCCCCCEEEECCHHHEEECCCCCHHHHHHHHCCCCCCHHCCCEEEEEEEEE
HDSPTTTASQLVGKKVGAVAADAFGGYLLGYKELLGAGLDPEKDLQLHFSGYPADALLYQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHH
LRDRALDAVIVPVCLLEKMQAEGLLQASDYRALLAKHSGQPCLTSTELYPNWSFAALNHV
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHC
PDRLADELTRQLLQMNAPGLPVWGAPASSRQVNQLLRDLNIHPSQRSLWQEVTLWAQQHL
HHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LLLGGIFGGMLLLGANHLWIGHLVRRRGRQLEQMHQTLRARETALAQAQRLSTLGEMASG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAHELNQPLAAIRHYAEGCRIRLERSDRQHELLPILEQIGQQAQRGAESIVNLRRWASKT
HHHHHCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PHHESTRPLLLRPLVEHLIKLMQIEQQYPLCRITLAIPAQSQLYSQTTLLEQVLTNLLSN
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
SLQAGAQQITLRLEVDQHQQRLIVEDDGGGLNAEQLTLPFVPFRSSKPEGLGLGLVICQR
HHHCCCEEEEEEEEECCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHH
LLKHQGGDLTLENYFSASQQQGLRVTLYFPVIQQETCHGVNTSGR
HHHCCCCCEEHHHHHCHHHHCCCEEEEEEEEHHHHHCCCCCCCCC
>Mature Secondary Structure
MKRAALILLLGGWLNVAWAGQWTIAVLALRGDAHALAQWQPLVDHLNRQFPGDHFQLSPL
CCCEEEEEEECCCCCEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEECCC
SLAGMDEAVRNERVDFLLTNPAQYVQLDNRYPLRWLVSLRSSQQPQQASGNVVGSAILVR
HHCCCHHHHHCCCCCEEEECCHHHEEECCCCCHHHHHHHHCCCCCCHHCCCEEEEEEEEE
HDSPTTTASQLVGKKVGAVAADAFGGYLLGYKELLGAGLDPEKDLQLHFSGYPADALLYQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHH
LRDRALDAVIVPVCLLEKMQAEGLLQASDYRALLAKHSGQPCLTSTELYPNWSFAALNHV
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHC
PDRLADELTRQLLQMNAPGLPVWGAPASSRQVNQLLRDLNIHPSQRSLWQEVTLWAQQHL
HHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LLLGGIFGGMLLLGANHLWIGHLVRRRGRQLEQMHQTLRARETALAQAQRLSTLGEMASG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAHELNQPLAAIRHYAEGCRIRLERSDRQHELLPILEQIGQQAQRGAESIVNLRRWASKT
HHHHHCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PHHESTRPLLLRPLVEHLIKLMQIEQQYPLCRITLAIPAQSQLYSQTTLLEQVLTNLLSN
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
SLQAGAQQITLRLEVDQHQQRLIVEDDGGGLNAEQLTLPFVPFRSSKPEGLGLGLVICQR
HHHCCCEEEEEEEEECCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHH
LLKHQGGDLTLENYFSASQQQGLRVTLYFPVIQQETCHGVNTSGR
HHHCCCCCEEHHHHHCHHHHCCCEEEEEEEEHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]