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The map label for this gene is apbE [H]

Identifier: 157369204

GI number: 157369204

Start: 1057070

End: 1058101

Strand: Direct

Name: apbE [H]

Synonym: Spro_0959

Alternate gene names: 157369204

Gene position: 1057070-1058101 (Clockwise)

Preceding gene: 157369203

Following gene: 157369205

Centisome position: 19.4

GC content: 58.82

Gene sequence:

>1032_bases
ATGCGCGCATGGGCAATGAAGGGGTTGATGACGACGGTGGCGCTCAGCGCCACCCTGTTATTGACCGGCTGCGGACCGGA
GCAGGTCAATCTCGATGGCAAAACCATGGGGACATCGTATTCAGTTCGCTACGTCACCGGGGACGACACGCCGTCTGCCG
CCAAAATGCAGGCGGAGATCGACAAGCGTCTGGAGTTGGTGAACGACCAAATGTCCACCTACCGGCCAGGCTCTGAACTG
AGCCGCTTCAACGCCAGTCGCGCTGTTGATAAACCCTTCCCGGTATCGGCGGCAACCACCGAGGTGGTGCTGGAAGCGCT
GCGCATTAACCGCGTCACCGACGGTGCGCTGGACGTGACCGTCGGGCCGCTGGTTAATCTGTGGGGCTTTGGCCCGGAAG
GGCGGCCGGACAAGGTGCCGAGCGCTGCCGAACTGGAGCGCCGCCGAGCCTGGACCGGTATCGACAAACTGTCGGTGCAG
GGCAATGCATTGGTAAAGAGCATTCCTGAGCTGTATGTCGATCTCTCCTCGATCGCCAAGGGCTACGGGGTGGATGTAAT
TGCCCAGTATCTGCAGTCGCAGCAGGTCAAGAACTACATGGTGGATATTGGCGGTGAGGTACGTACTCGTGGCCATAACG
GTGAGAAAAAACCGTGGCGTATCGCCATTGAACGGCCGACGGCCGGCATGGAGCAGAAGGCACAACTGGTGATCCAGCCG
GGCGAGATGTCGATCGCCACCTCGGGGGATTATCGCAACTACTTCGAACAGGGCGGCGTGCGTTATTCTCACACCATAGA
TCCGGTTACCGGCAAGCCTATCCATCATCATCTGGTGTCGGTTACGGTGCTGAGCCCGACCTGTATGGCCGCCGATGGTT
TGTCGACCGGGTTGAACGTATTGGGGCCGGAGCGCGGCATGGCGTTGGCGAACCTGATGGGGATCCCGGTGTTCATGATT
GTGAAAACCACCAAAGGTTTTGAAGAGCGCTACTCCGAAGCGTTCAAACCCTATTTGAACAAGAGCTTGTGA

Upstream 100 bases:

>100_bases
CATGTGCGGTCCGCCAATGATGAACGCCGCAGTGATCAAGATGCTGAAAGACCTGGGCGTTGAAGACGAAAATATCATGC
TTGATGACTTTGGTGGCTAA

Downstream 100 bases:

>100_bases
GGTCGCTATGTTGACAGTATTTGTCGCCAGCTTTGTGTTGTTTCTGCTGATTGTCGGCGGGATGTCGTTGGGGTACGTGT
TCAAGCGTAAAAGCCTGCAG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MRAWAMKGLMTTVALSATLLLTGCGPEQVNLDGKTMGTSYSVRYVTGDDTPSAAKMQAEIDKRLELVNDQMSTYRPGSEL
SRFNASRAVDKPFPVSAATTEVVLEALRINRVTDGALDVTVGPLVNLWGFGPEGRPDKVPSAAELERRRAWTGIDKLSVQ
GNALVKSIPELYVDLSSIAKGYGVDVIAQYLQSQQVKNYMVDIGGEVRTRGHNGEKKPWRIAIERPTAGMEQKAQLVIQP
GEMSIATSGDYRNYFEQGGVRYSHTIDPVTGKPIHHHLVSVTVLSPTCMAADGLSTGLNVLGPERGMALANLMGIPVFMI
VKTTKGFEERYSEAFKPYLNKSL

Sequences:

>Translated_343_residues
MRAWAMKGLMTTVALSATLLLTGCGPEQVNLDGKTMGTSYSVRYVTGDDTPSAAKMQAEIDKRLELVNDQMSTYRPGSEL
SRFNASRAVDKPFPVSAATTEVVLEALRINRVTDGALDVTVGPLVNLWGFGPEGRPDKVPSAAELERRRAWTGIDKLSVQ
GNALVKSIPELYVDLSSIAKGYGVDVIAQYLQSQQVKNYMVDIGGEVRTRGHNGEKKPWRIAIERPTAGMEQKAQLVIQP
GEMSIATSGDYRNYFEQGGVRYSHTIDPVTGKPIHHHLVSVTVLSPTCMAADGLSTGLNVLGPERGMALANLMGIPVFMI
VKTTKGFEERYSEAFKPYLNKSL
>Mature_343_residues
MRAWAMKGLMTTVALSATLLLTGCGPEQVNLDGKTMGTSYSVRYVTGDDTPSAAKMQAEIDKRLELVNDQMSTYRPGSEL
SRFNASRAVDKPFPVSAATTEVVLEALRINRVTDGALDVTVGPLVNLWGFGPEGRPDKVPSAAELERRRAWTGIDKLSVQ
GNALVKSIPELYVDLSSIAKGYGVDVIAQYLQSQQVKNYMVDIGGEVRTRGHNGEKKPWRIAIERPTAGMEQKAQLVIQP
GEMSIATSGDYRNYFEQGGVRYSHTIDPVTGKPIHHHLVSVTVLSPTCMAADGLSTGLNVLGPERGMALANLMGIPVFMI
VKTTKGFEERYSEAFKPYLNKSL

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=339, Percent_Identity=42.4778761061947, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 37366; Mature: 37366

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAWAMKGLMTTVALSATLLLTGCGPEQVNLDGKTMGTSYSVRYVTGDDTPSAAKMQAEI
CCCHHHHHHHHHHHHHHHHEEECCCCCEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHH
DKRLELVNDQMSTYRPGSELSRFNASRAVDKPFPVSAATTEVVLEALRINRVTDGALDVT
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEE
VGPLVNLWGFGPEGRPDKVPSAAELERRRAWTGIDKLSVQGNALVKSIPELYVDLSSIAK
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHEECCCCHHHHHHHHHHHHHHHHHC
GYGVDVIAQYLQSQQVKNYMVDIGGEVRTRGHNGEKKPWRIAIERPTAGMEQKAQLVIQP
CCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEEC
GEMSIATSGDYRNYFEQGGVRYSHTIDPVTGKPIHHHLVSVTVLSPTCMAADGLSTGLNV
CCEEEEECCCHHHHHHHCCEEEEEEECCCCCCCHHHHEEEEEEECCHHHHHCCHHCCCHH
LGPERGMALANLMGIPVFMIVKTTKGFEERYSEAFKPYLNKSL
CCCCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRAWAMKGLMTTVALSATLLLTGCGPEQVNLDGKTMGTSYSVRYVTGDDTPSAAKMQAEI
CCCHHHHHHHHHHHHHHHHEEECCCCCEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHH
DKRLELVNDQMSTYRPGSELSRFNASRAVDKPFPVSAATTEVVLEALRINRVTDGALDVT
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEE
VGPLVNLWGFGPEGRPDKVPSAAELERRRAWTGIDKLSVQGNALVKSIPELYVDLSSIAK
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHEECCCCHHHHHHHHHHHHHHHHHC
GYGVDVIAQYLQSQQVKNYMVDIGGEVRTRGHNGEKKPWRIAIERPTAGMEQKAQLVIQP
CCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEEC
GEMSIATSGDYRNYFEQGGVRYSHTIDPVTGKPIHHHLVSVTVLSPTCMAADGLSTGLNV
CCEEEEECCCHHHHHHHCCEEEEEEECCCCCCCHHHHEEEEEEECCHHHHHCCHHCCCHH
LGPERGMALANLMGIPVFMIVKTTKGFEERYSEAFKPYLNKSL
CCCCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]