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The map label for this gene is nqrA

Identifier: 157369198

GI number: 157369198

Start: 1051227

End: 1052576

Strand: Direct

Name: nqrA

Synonym: Spro_0953

Alternate gene names: 157369198

Gene position: 1051227-1052576 (Clockwise)

Preceding gene: 157369196

Following gene: 157369199

Centisome position: 19.29

GC content: 59.19

Gene sequence:

>1350_bases
ATGATTAAAATCAGAAAAGGGTTAGATCTGCCCATTGCCGGAGCTCCGGCTCAGGCGATTCAGGACGGCCCAATCATTCA
GCATGTCGCCCTGCTTGGGGAAGATTATGTCGGAATGCGCCCGTCTATGCTGGTGCAGGAAGGCGAGAGCGTTAAGAAAG
GCCAGGCGCTGTTCGAAGATAAAAAGACCCCCGGGGTTTTCTTCACCGCTCCCGCCAGTGGCCGTATTCTTTCGATCAAC
CGCGGTGAACGGCGCGTATTGCAGTCGGTAGTTATCGCCGTTGAAAATGGCGGCGATGAGCAACTGGAGTTTGCTCATTA
TCCGGTTGCCGAACTGGCGATGCTGCCGCGGGAACAGGTTGAAAGCGAATTACTCGCCAGCGGTCTGTGGACTGCGCTAC
GTACCCGCCCATTCAGTAAAACGCCTGCACCGGGTAGCACTCCACGTGCCATTTTTGTTACCGCCATGGACAGCCAGCCG
CTGGCTGCCGATCCGCAGGTGATCATCGCCGAGCAGTTGGCAGCGTTCAACGCCGGACTTGCGGTATTGGCCCGGCTGAC
CGACGGCAAGGTTCACGTTTGCCACGCCGCGGGCGCGAACCTGGGCAAGCAACCCGATGCGCAGGTGACCTATAACGAAT
TCGCCGGTCCACATCCTGCCGGGTTGGTGGGCACCCATATTCATTTCCTCGAGCCGGTCAGTTTGAAAAAAACCGTCTGG
CATATCGGCTATCAGGATGCGATCGCCATCGGCACCTTGTTCACCACCGGCAAACTCGATACCCGTCGGGTGGTGGCACT
GGCCGGGCCGCAGGTGGAACAGCCGGTGTTGCTGCGCACCCGGTTGGGCGCCAGCATCGACGAACTGACCGCCGGGCGTC
TGAAAGCCGGTGAGAACCGGGTGATTTCCGGTTCGGTGCTGAGCGGCACCCACGTTGCCGGGCCGAACGCTTACCTCGGC
CGTTTCCATTCGCTGGTTTCCGTACTGCAGGAAGGGCGTGATAAAGAGCTGTTTGGTTGGATCGCGCCATCACCGGATAA
ATTTTCCATCACCCGTACTACGCTGGGCCATTTCCTGAAGAACAAACTGTTCGCCTTCTCGACCACCACCCACGGCGGTG
AGCGTGCAATGGTGCCGATCGGCAACTACGAGCGGGTAATGCCGCTGGATATCCTGCCGACCCTGCTGCTGCGCGACCTG
CTGGCGGGTGACAGCGACAGCGCACAGGCGTTGGGCTGTCTGGAGCTGGATGAAGAAGATCTGGCGCTGTGCACCTTCGT
TTGCCCCGGCAAGTATGAATACGCTCCGGTGCTGCGCGATGTGCTGACCAAGATTGAGCAGGAAGGATAA

Upstream 100 bases:

>100_bases
ACCCAGAGGCTGCTGAAGCGGCCTCATCATCCAGGCATCGTCAGCACCAGCCTCTGGGGCCGGTAAGACGTGTGAAACTA
ACCAACATCGTATAAATCCT

Downstream 100 bases:

>100_bases
CCGATGGGCCTGAAGAACTTTTTTGAAAAAATCGAGCATCACTTCACACCGGGCGGCAAGCTGGAAAAGTGGTACCCGCT
GTTTGAAGCGACTACCACGG

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MIKIRKGLDLPIAGAPAQAIQDGPIIQHVALLGEDYVGMRPSMLVQEGESVKKGQALFEDKKTPGVFFTAPASGRILSIN
RGERRVLQSVVIAVENGGDEQLEFAHYPVAELAMLPREQVESELLASGLWTALRTRPFSKTPAPGSTPRAIFVTAMDSQP
LAADPQVIIAEQLAAFNAGLAVLARLTDGKVHVCHAAGANLGKQPDAQVTYNEFAGPHPAGLVGTHIHFLEPVSLKKTVW
HIGYQDAIAIGTLFTTGKLDTRRVVALAGPQVEQPVLLRTRLGASIDELTAGRLKAGENRVISGSVLSGTHVAGPNAYLG
RFHSLVSVLQEGRDKELFGWIAPSPDKFSITRTTLGHFLKNKLFAFSTTTHGGERAMVPIGNYERVMPLDILPTLLLRDL
LAGDSDSAQALGCLELDEEDLALCTFVCPGKYEYAPVLRDVLTKIEQEG

Sequences:

>Translated_449_residues
MIKIRKGLDLPIAGAPAQAIQDGPIIQHVALLGEDYVGMRPSMLVQEGESVKKGQALFEDKKTPGVFFTAPASGRILSIN
RGERRVLQSVVIAVENGGDEQLEFAHYPVAELAMLPREQVESELLASGLWTALRTRPFSKTPAPGSTPRAIFVTAMDSQP
LAADPQVIIAEQLAAFNAGLAVLARLTDGKVHVCHAAGANLGKQPDAQVTYNEFAGPHPAGLVGTHIHFLEPVSLKKTVW
HIGYQDAIAIGTLFTTGKLDTRRVVALAGPQVEQPVLLRTRLGASIDELTAGRLKAGENRVISGSVLSGTHVAGPNAYLG
RFHSLVSVLQEGRDKELFGWIAPSPDKFSITRTTLGHFLKNKLFAFSTTTHGGERAMVPIGNYERVMPLDILPTLLLRDL
LAGDSDSAQALGCLELDEEDLALCTFVCPGKYEYAPVLRDVLTKIEQEG
>Mature_449_residues
MIKIRKGLDLPIAGAPAQAIQDGPIIQHVALLGEDYVGMRPSMLVQEGESVKKGQALFEDKKTPGVFFTAPASGRILSIN
RGERRVLQSVVIAVENGGDEQLEFAHYPVAELAMLPREQVESELLASGLWTALRTRPFSKTPAPGSTPRAIFVTAMDSQP
LAADPQVIIAEQLAAFNAGLAVLARLTDGKVHVCHAAGANLGKQPDAQVTYNEFAGPHPAGLVGTHIHFLEPVSLKKTVW
HIGYQDAIAIGTLFTTGKLDTRRVVALAGPQVEQPVLLRTRLGASIDELTAGRLKAGENRVISGSVLSGTHVAGPNAYLG
RFHSLVSVLQEGRDKELFGWIAPSPDKFSITRTTLGHFLKNKLFAFSTTTHGGERAMVPIGNYERVMPLDILPTLLLRDL
LAGDSDSAQALGCLELDEEDLALCTFVCPGKYEYAPVLRDVLTKIEQEG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRA_SERP5 (A8GAB9)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477187.1
- STRING:   A8GAB9
- GeneID:   5603696
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0953
- eggNOG:   COG1726
- HOGENOM:   HBG413878
- OMA:   EYGPILR
- ProtClustDB:   PRK05352
- BioCyc:   SPRO399741:SPRO_0953-MONOMER
- HAMAP:   MF_00425
- InterPro:   IPR008703
- InterPro:   IPR022615
- TIGRFAMs:   TIGR01936

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB

EC number: NA

Molecular weight: Translated: 48295; Mature: 48295

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIRKGLDLPIAGAPAQAIQDGPIIQHVALLGEDYVGMRPSMLVQEGESVKKGQALFED
CEEECCCCCCCCCCCCHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHC
KKTPGVFFTAPASGRILSINRGERRVLQSVVIAVENGGDEQLEFAHYPVAELAMLPREQV
CCCCCEEEECCCCCEEEEECCCHHHHHHHHEEEEECCCCCCEEEECCCHHHHHHCCHHHH
ESELLASGLWTALRTRPFSKTPAPGSTPRAIFVTAMDSQPLAADPQVIIAEQLAAFNAGL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCH
AVLARLTDGKVHVCHAAGANLGKQPDAQVTYNEFAGPHPAGLVGTHIHFLEPVSLKKTVW
HEEEEECCCCEEEEEECCCCCCCCCCCEEEHHHCCCCCCCCHHCCCHHEECCCCHHHHHH
HIGYQDAIAIGTLFTTGKLDTRRVVALAGPQVEQPVLLRTRLGASIDELTAGRLKAGENR
HCCCHHHHEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHCCCCHHHHHHCHHCCCCCE
VISGSVLSGTHVAGPNAYLGRFHSLVSVLQEGRDKELFGWIAPSPDKFSITRTTLGHFLK
EEECCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHHHHHHH
NKLFAFSTTTHGGERAMVPIGNYERVMPLDILPTLLLRDLLAGDSDSAQALGCLELDEED
CCEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
LALCTFVCPGKYEYAPVLRDVLTKIEQEG
CEEEEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKIRKGLDLPIAGAPAQAIQDGPIIQHVALLGEDYVGMRPSMLVQEGESVKKGQALFED
CEEECCCCCCCCCCCCHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHC
KKTPGVFFTAPASGRILSINRGERRVLQSVVIAVENGGDEQLEFAHYPVAELAMLPREQV
CCCCCEEEECCCCCEEEEECCCHHHHHHHHEEEEECCCCCCEEEECCCHHHHHHCCHHHH
ESELLASGLWTALRTRPFSKTPAPGSTPRAIFVTAMDSQPLAADPQVIIAEQLAAFNAGL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCH
AVLARLTDGKVHVCHAAGANLGKQPDAQVTYNEFAGPHPAGLVGTHIHFLEPVSLKKTVW
HEEEEECCCCEEEEEECCCCCCCCCCCEEEHHHCCCCCCCCHHCCCHHEECCCCHHHHHH
HIGYQDAIAIGTLFTTGKLDTRRVVALAGPQVEQPVLLRTRLGASIDELTAGRLKAGENR
HCCCHHHHEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHCCCCHHHHHHCHHCCCCCE
VISGSVLSGTHVAGPNAYLGRFHSLVSVLQEGRDKELFGWIAPSPDKFSITRTTLGHFLK
EEECCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHHHHHHH
NKLFAFSTTTHGGERAMVPIGNYERVMPLDILPTLLLRDLLAGDSDSAQALGCLELDEED
CCEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
LALCTFVCPGKYEYAPVLRDVLTKIEQEG
CEEEEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA