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The map label for this gene is ybdL [H]

Identifier: 157369186

GI number: 157369186

Start: 1039273

End: 1040433

Strand: Reverse

Name: ybdL [H]

Synonym: Spro_0941

Alternate gene names: 157369186

Gene position: 1040433-1039273 (Counterclockwise)

Preceding gene: 157369190

Following gene: 157369185

Centisome position: 19.09

GC content: 59.95

Gene sequence:

>1161_bases
ATGAGCACTTCAGCACTGATCCCCGAAAGTAAACTACCCGCGCTGGGCACCACCATTTTCACCCAGATGAGTGCGCTGGC
GGCGCAGCATCAGGCAATCAACCTGTCGCAGGGCTTCCCCGATTTCGATGGCCCGGACTACCTGAAAGAACGTCTGGCCT
GGCATGTCAGCCAGGGGGCGAACCAATATGCTCCGATGACCGGCGTTGCCCCACTGCGCGAAGCCATCGCCGAGAAAACC
GCGGCTCTGTACGGCTGGCTACCGGACGCCACTAACGAAGTCACCATCACGGCGGGTGCCACCGAGGCACTGTTCGCCGC
CATCAGCGCCCTGGTGCGCCCCGGTGATGAAGTTGTCTGTTTTGATCCCAGCTACGACAGCTATGCGCCGGCGGTGACCC
TATCCGGCGGCACGCTAAAACGCATTGCGCTGCAGCCCCCGGCGTTCAGCGTCGACTGGCAACAGTTCGGCGAGTTGCTG
TCACCACGCACCCGGCTGGTGATCCTCAATACGCCGCACAATCCTTCTGCTACTGCCTGGCAGGCGGAAGATATGCAGCA
ACTGTGGCACGCCATTAGCGATCGCGAAATCTACGTGCTGAGTGATGAAGTCTACGAACACATTTGTTTCGCAAGGGGCG
GCCACACCAGCGTCCTGGCTCACCCGCAGCTGCGCCAGCGCGCCATCGCGGTGTCCTCTTTCGGCAAGACCTTCCACATG
ACCGGCTGGAAAGTGGGTTACTGCGTGGCCCCGGTAGCGCTGAGCGCAGAAGTACGCAAGGTGCATCAGTACCTGACCTT
CTCGGTCAATACCCCGGCCCAGTTGGCGCTGGCGGATATGCTGCGCAGCGAGCCTGAACACTGGCAACAGCTGTCGGCAT
TTTACCGCGCCAAGCGCGATCGTTTTGTGCAGGCGCTGTCCAGCAGTCGACTGGAAATTTTGCCTTGCGAAGGTACATAC
TTCTTACTGGCAGATTACAGCGCCGTTTCCGATTTGGACGACGTGGCGTTCTGCCATTGGTTAACCGAGCACGTAGGCGT
GGCGGCGATCCCGCTGTCGGTCTTCTGTGCCGATCCTTTCCCCCATAAATTGATCCGGCTGTGCTTCGCTAAACAGGATG
CCACGCTGGATGCGGCTGCGGAGCGGTTATGTCGACTTTAA

Upstream 100 bases:

>100_bases
AAGACTTTTTCTTCATTTAGCCATCTAAGCGTCTTGATTGCCAAATACTAACATCGTGTTATATTGACGGCAACATAAGC
GCCAGGAGTATTAGCCTACG

Downstream 100 bases:

>100_bases
AAATTACCCTGTTGCAGCAACCCCTGGTTTGGCGTGATGGCGAAGCTAACCTGCGGCATTTTGATGAGCTGTTGGCGCCA
TTAAGCGGCCGCGATTTGAT

Product: putative aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSTSALIPESKLPALGTTIFTQMSALAAQHQAINLSQGFPDFDGPDYLKERLAWHVSQGANQYAPMTGVAPLREAIAEKT
AALYGWLPDATNEVTITAGATEALFAAISALVRPGDEVVCFDPSYDSYAPAVTLSGGTLKRIALQPPAFSVDWQQFGELL
SPRTRLVILNTPHNPSATAWQAEDMQQLWHAISDREIYVLSDEVYEHICFARGGHTSVLAHPQLRQRAIAVSSFGKTFHM
TGWKVGYCVAPVALSAEVRKVHQYLTFSVNTPAQLALADMLRSEPEHWQQLSAFYRAKRDRFVQALSSSRLEILPCEGTY
FLLADYSAVSDLDDVAFCHWLTEHVGVAAIPLSVFCADPFPHKLIRLCFAKQDATLDAAAERLCRL

Sequences:

>Translated_386_residues
MSTSALIPESKLPALGTTIFTQMSALAAQHQAINLSQGFPDFDGPDYLKERLAWHVSQGANQYAPMTGVAPLREAIAEKT
AALYGWLPDATNEVTITAGATEALFAAISALVRPGDEVVCFDPSYDSYAPAVTLSGGTLKRIALQPPAFSVDWQQFGELL
SPRTRLVILNTPHNPSATAWQAEDMQQLWHAISDREIYVLSDEVYEHICFARGGHTSVLAHPQLRQRAIAVSSFGKTFHM
TGWKVGYCVAPVALSAEVRKVHQYLTFSVNTPAQLALADMLRSEPEHWQQLSAFYRAKRDRFVQALSSSRLEILPCEGTY
FLLADYSAVSDLDDVAFCHWLTEHVGVAAIPLSVFCADPFPHKLIRLCFAKQDATLDAAAERLCRL
>Mature_385_residues
STSALIPESKLPALGTTIFTQMSALAAQHQAINLSQGFPDFDGPDYLKERLAWHVSQGANQYAPMTGVAPLREAIAEKTA
ALYGWLPDATNEVTITAGATEALFAAISALVRPGDEVVCFDPSYDSYAPAVTLSGGTLKRIALQPPAFSVDWQQFGELLS
PRTRLVILNTPHNPSATAWQAEDMQQLWHAISDREIYVLSDEVYEHICFARGGHTSVLAHPQLRQRAIAVSSFGKTFHMT
GWKVGYCVAPVALSAEVRKVHQYLTFSVNTPAQLALADMLRSEPEHWQQLSAFYRAKRDRFVQALSSSRLEILPCEGTYF
LLADYSAVSDLDDVAFCHWLTEHVGVAAIPLSVFCADPFPHKLIRLCFAKQDATLDAAAERLCRL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=34.4139650872818, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI56713256, Length=402, Percent_Identity=34.3283582089552, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI95147551, Length=410, Percent_Identity=31.4634146341463, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI169881279, Length=410, Percent_Identity=31.4634146341463, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI169881281, Length=408, Percent_Identity=27.2058823529412, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI4507369, Length=338, Percent_Identity=21.8934911242604, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=77.4611398963731, Blast_Score=628, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=293, Percent_Identity=24.9146757679181, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788627, Length=280, Percent_Identity=23.9285714285714, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787710, Length=298, Percent_Identity=26.1744966442953, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=421, Percent_Identity=31.5914489311164, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI71994476, Length=421, Percent_Identity=31.5914489311164, Blast_Score=211, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17567369, Length=400, Percent_Identity=27.75, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17567663, Length=345, Percent_Identity=20, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=29.639175257732, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28573069, Length=401, Percent_Identity=32.1695760598504, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24646114, Length=401, Percent_Identity=32.1695760598504, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI28573067, Length=401, Percent_Identity=32.1695760598504, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI28573065, Length=401, Percent_Identity=32.1695760598504, Blast_Score=213, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42482; Mature: 42350

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSALIPESKLPALGTTIFTQMSALAAQHQAINLSQGFPDFDGPDYLKERLAWHVSQGA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHCCC
NQYAPMTGVAPLREAIAEKTAALYGWLPDATNEVTITAGATEALFAAISALVRPGDEVVC
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEE
FDPSYDSYAPAVTLSGGTLKRIALQPPAFSVDWQQFGELLSPRTRLVILNTPHNPSATAW
ECCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCC
QAEDMQQLWHAISDREIYVLSDEVYEHICFARGGHTSVLAHPQLRQRAIAVSSFGKTFHM
CHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCEEEE
TGWKVGYCVAPVALSAEVRKVHQYLTFSVNTPAQLALADMLRSEPEHWQQLSAFYRAKRD
CCCEEHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RFVQALSSSRLEILPCEGTYFLLADYSAVSDLDDVAFCHWLTEHVGVAAIPLSVFCADPF
HHHHHHHCCCEEEEECCCCEEEEECCHHHCCHHHHHHHHHHHHHCCEEEEEHEEEECCCC
PHKLIRLCFAKQDATLDAAAERLCRL
HHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
STSALIPESKLPALGTTIFTQMSALAAQHQAINLSQGFPDFDGPDYLKERLAWHVSQGA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHCCC
NQYAPMTGVAPLREAIAEKTAALYGWLPDATNEVTITAGATEALFAAISALVRPGDEVVC
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEE
FDPSYDSYAPAVTLSGGTLKRIALQPPAFSVDWQQFGELLSPRTRLVILNTPHNPSATAW
ECCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCC
QAEDMQQLWHAISDREIYVLSDEVYEHICFARGGHTSVLAHPQLRQRAIAVSSFGKTFHM
CHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCEEEE
TGWKVGYCVAPVALSAEVRKVHQYLTFSVNTPAQLALADMLRSEPEHWQQLSAFYRAKRD
CCCEEHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RFVQALSSSRLEILPCEGTYFLLADYSAVSDLDDVAFCHWLTEHVGVAAIPLSVFCADPF
HHHHHHHCCCEEEEECCCCEEEEECCHHHCCHHHHHHHHHHHHHCCEEEEEHEEEECCCC
PHKLIRLCFAKQDATLDAAAERLCRL
HHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]