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The map label for this gene is dnaQ [H]

Identifier: 157369157

GI number: 157369157

Start: 1010911

End: 1011651

Strand: Direct

Name: dnaQ [H]

Synonym: Spro_0912

Alternate gene names: 157369157

Gene position: 1010911-1011651 (Clockwise)

Preceding gene: 157369155

Following gene: 157369159

Centisome position: 18.55

GC content: 54.93

Gene sequence:

>741_bases
ATGATCTCTACAACCACCAGACAGATTGTCCTCGATACCGAAACCACCGGTATGAACAAACTCGGGGTGCATTACGAAGG
CCACCGCATCATTGAAATTGGTGCGCTGGAAGTGATTAACCGCCGCCCAACCGGTCGTCACTACCATGTTTACATCAAGC
CGGATCGGCTGGTGGATCCTGAGGCCTATGGGGTTCACGGCATCAGCGATGAGTTCCTGGCGGATAAACCGACCTTTGCC
CAAATTGCCGATGAGTTTATCGACTTTATCCGCGGCGGCGAGTTAGTCATCCATAACGCGGCGTTCGACATCGGCTTTAT
GGATCACGAATTCCGCATGTTGCAGCAGGGCATCCCGAAGACCGATACCTTCTGCACCATCACCGACAGCCTGTTAATGG
CGCGCCGCCTGTTCCCCGGCAAGCGTAACAACCTCGATGCGTTATGCAGCCGTTACGAGATAGACAACAGCAAGCGTACG
CTGCACGGCGCCTTGCTCGATGCCGAGATCCTGGCGGAAGTCTATCTGGCGATGACCGGTGGTCAAACCTCGATGGCTTT
CCAGATGGAAGGCGATACGCAAAATAGCAATTCAACGCAGGACATTCAGCGCATTGTGCGCCCGGCGACGACGATGAAAG
TCGTCTATGCCAGCGATGAAGAAGTGGTGGCCCACGAAGCGCGTCTGGATTTAGTGGCGAAAAAGGGCGGCAGTTGCCTG
TGGCGTACCGAAGTGGAATAA

Upstream 100 bases:

>100_bases
CGGTGAAAATTTCTACCTGTTTGAGCATCTCTGGTAGACTCTTCCTATCAGTTTTATAAAAGCCAAGTCTGACATAAACA
AGCGCTGCGAGCACTGCAAT

Downstream 100 bases:

>100_bases
CGGCGTTTTAATCTGGGCCGATAATCTTTCGGCCCGGTTAGCTGAAAAACTGTGCAAACGGTTCATTTGGTAAGAAAAAG
GCATTGACGCCATAGTGGCT

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MISTTTRQIVLDTETTGMNKLGVHYEGHRIIEIGALEVINRRPTGRHYHVYIKPDRLVDPEAYGVHGISDEFLADKPTFA
QIADEFIDFIRGGELVIHNAAFDIGFMDHEFRMLQQGIPKTDTFCTITDSLLMARRLFPGKRNNLDALCSRYEIDNSKRT
LHGALLDAEILAEVYLAMTGGQTSMAFQMEGDTQNSNSTQDIQRIVRPATTMKVVYASDEEVVAHEARLDLVAKKGGSCL
WRTEVE

Sequences:

>Translated_246_residues
MISTTTRQIVLDTETTGMNKLGVHYEGHRIIEIGALEVINRRPTGRHYHVYIKPDRLVDPEAYGVHGISDEFLADKPTFA
QIADEFIDFIRGGELVIHNAAFDIGFMDHEFRMLQQGIPKTDTFCTITDSLLMARRLFPGKRNNLDALCSRYEIDNSKRT
LHGALLDAEILAEVYLAMTGGQTSMAFQMEGDTQNSNSTQDIQRIVRPATTMKVVYASDEEVVAHEARLDLVAKKGGSCL
WRTEVE
>Mature_246_residues
MISTTTRQIVLDTETTGMNKLGVHYEGHRIIEIGALEVINRRPTGRHYHVYIKPDRLVDPEAYGVHGISDEFLADKPTFA
QIADEFIDFIRGGELVIHNAAFDIGFMDHEFRMLQQGIPKTDTFCTITDSLLMARRLFPGKRNNLDALCSRYEIDNSKRT
LHGALLDAEILAEVYLAMTGGQTSMAFQMEGDTQNSNSTQDIQRIVRPATTMKVVYASDEEVVAHEARLDLVAKKGGSCL
WRTEVE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=242, Percent_Identity=76.0330578512397, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 27664; Mature: 27664

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTTTRQIVLDTETTGMNKLGVHYEGHRIIEIGALEVINRRPTGRHYHVYIKPDRLVDP
CCCCCCEEEEEECCCCCCCCCCEEECCCEEEEECHHHHCCCCCCCCEEEEEECCCCCCCC
EAYGVHGISDEFLADKPTFAQIADEFIDFIRGGELVIHNAAFDIGFMDHEFRMLQQGIPK
CCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECEEECCCCHHHHHHHHCCCCC
TDTFCTITDSLLMARRLFPGKRNNLDALCSRYEIDNSKRTLHGALLDAEILAEVYLAMTG
CCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GQTSMAFQMEGDTQNSNSTQDIQRIVRPATTMKVVYASDEEVVAHEARLDLVAKKGGSCL
CCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHEEECCCCCEE
WRTEVE
EEEECC
>Mature Secondary Structure
MISTTTRQIVLDTETTGMNKLGVHYEGHRIIEIGALEVINRRPTGRHYHVYIKPDRLVDP
CCCCCCEEEEEECCCCCCCCCCEEECCCEEEEECHHHHCCCCCCCCEEEEEECCCCCCCC
EAYGVHGISDEFLADKPTFAQIADEFIDFIRGGELVIHNAAFDIGFMDHEFRMLQQGIPK
CCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECEEECCCCHHHHHHHHCCCCC
TDTFCTITDSLLMARRLFPGKRNNLDALCSRYEIDNSKRTLHGALLDAEILAEVYLAMTG
CCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GQTSMAFQMEGDTQNSNSTQDIQRIVRPATTMKVVYASDEEVVAHEARLDLVAKKGGSCL
CCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHEEECCCCCEE
WRTEVE
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]