BacMap

Definition	Serratia proteamaculans 568 chromosome, complete genome.
Accession	NC_009832
Length	5,448,853

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The map label for this gene is fabG [H]

Identifier: 157369147

GI number: 157369147

Start: 1001178

End: 1001909

Strand: Direct

Name: fabG [H]

Synonym: Spro_0902

Alternate gene names: 157369147

Gene position: 1001178-1001909 (Clockwise)

Preceding gene: 157369146

Following gene: 157369148

Centisome position: 18.37

GC content: 57.79

Gene sequence:

>732_bases
ATGATGCGTTCCGTTTTAGTCACCGGCGCCAGTAAAGGGATCGGTCAGGCTATTGCCTGCCGCCTGGCTGCCGATGGCTT
TTTGATAGCCGTTCACTACCACAGCGATAAGACCGGGGCCGAACACACACTGCAGCAGATTATCAGCGCCGGCGGGAAAG
GGCGGCTGATTCAGTTTGATATCAGCAATCGCAGCCAGTGCCGTGAGGTGCTGGAGCAGGATATTGAAACCCACGGCGCC
TATTATGGCGTGGTGAACAATGCCGGTATTACCCGCGATGGCGCTTTCCCTGCGCTGAGTGAAGATGACTGGGATGGCGT
GATCCATACCAATCTCGACAGCTTCTACAACGTACTGCACCCCTGCGTGATGCCGATGATTGGCCTGCGCAAGGGTGGGC
GGATCGTCGCGCTGTCGTCGGTTTCCGGCGTGATGGGTAACCGTGGGCAGGTCAACTACAGTGCGGCCAAAGCAGGGGTA
ATTGGTGCCTGCAAGGCACTGGCGATTGAGCTGGCGAAACGCAAAATCACCGTTAACTGCATTGCGCCTGGGCTGATTGA
CACCGGCATGATCGACATGGAGCCGGCGGCGCTGGATGAAGCGATGCGCGTTATTCCGCTCAAACGCATGGGCTCGGCGG
AAGAGGTGGCCGGGCTGGCCAGCTATCTGATGTCGGATATCGCCGGCTATGTGACGCGGCAGGTCATTTCCATTAATGGA
GGAATGGTATGA

Upstream 100 bases:

>100_bases
AAATCAGTATCGATAATGTGCGCATCGCACAGGGCAGGCTGAACACTTACCAGCCTGATCAACAAGAAATCATTCAATTG
ACGACCTTAAGGGGAGACGC

Downstream 100 bases:

>100_bases
CACAACGAGTGGTAGTTACCGGCATGGCAGGCGTGACCGCGTTTGGCAATAGCTGGGCAGACGTATCCAGCCGTCTGCAG
CAGGGCAAGAATGCGGTGCG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MMRSVLVTGASKGIGQAIACRLAADGFLIAVHYHSDKTGAEHTLQQIISAGGKGRLIQFDISNRSQCREVLEQDIETHGA
YYGVVNNAGITRDGAFPALSEDDWDGVIHTNLDSFYNVLHPCVMPMIGLRKGGRIVALSSVSGVMGNRGQVNYSAAKAGV
IGACKALAIELAKRKITVNCIAPGLIDTGMIDMEPAALDEAMRVIPLKRMGSAEEVAGLASYLMSDIAGYVTRQVISING
GMV

Sequences:

>Translated_243_residues
MMRSVLVTGASKGIGQAIACRLAADGFLIAVHYHSDKTGAEHTLQQIISAGGKGRLIQFDISNRSQCREVLEQDIETHGA
YYGVVNNAGITRDGAFPALSEDDWDGVIHTNLDSFYNVLHPCVMPMIGLRKGGRIVALSSVSGVMGNRGQVNYSAAKAGV
IGACKALAIELAKRKITVNCIAPGLIDTGMIDMEPAALDEAMRVIPLKRMGSAEEVAGLASYLMSDIAGYVTRQVISING
GMV
>Mature_243_residues
MMRSVLVTGASKGIGQAIACRLAADGFLIAVHYHSDKTGAEHTLQQIISAGGKGRLIQFDISNRSQCREVLEQDIETHGA
YYGVVNNAGITRDGAFPALSEDDWDGVIHTNLDSFYNVLHPCVMPMIGLRKGGRIVALSSVSGVMGNRGQVNYSAAKAGV
IGACKALAIELAKRKITVNCIAPGLIDTGMIDMEPAALDEAMRVIPLKRMGSAEEVAGLASYLMSDIAGYVTRQVISING
GMV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=246, Percent_Identity=35.3658536585366, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=31.2757201646091, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=34.453781512605, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI4504505, Length=216, Percent_Identity=36.5740740740741, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=28.3400809716599, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=31.2, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI66933014, Length=210, Percent_Identity=29.5238095238095, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=26.8595041322314, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4503301, Length=204, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=28.1407035175879, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI126723191, Length=180, Percent_Identity=29.4444444444444, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI59889578, Length=215, Percent_Identity=29.7674418604651, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=41.0788381742739, Blast_Score=163, Evalue=8e-42,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=32.7868852459016, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=35.6275303643725, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=33.2, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=27.8225806451613, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=28.6307053941909, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=31.8181818181818, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=28.6885245901639, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=28, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=27.1604938271605, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=27.9352226720648, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=27.027027027027, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786701, Length=196, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=36.6255144032922, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17555706, Length=239, Percent_Identity=35.5648535564854, Blast_Score=133, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17568967, Length=220, Percent_Identity=34.0909090909091, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=29.4354838709677, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=30.4, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=31.0880829015544, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=26.7206477732794, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=26.8774703557312, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=28.0155642023346, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=26.1904761904762, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=27.34375, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=245, Percent_Identity=28.1632653061224, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=26.6409266409266, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=26.7206477732794, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=190, Percent_Identity=34.7368421052632, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6324126, Length=186, Percent_Identity=31.1827956989247, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322227, Length=198, Percent_Identity=29.2929292929293, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=36.6666666666667, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=31.8181818181818, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=33.8709677419355, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=31.8548387096774, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=33.1967213114754, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=28.4552845528455, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=30.4878048780488, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=34.3915343915344, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24640492, Length=208, Percent_Identity=28.3653846153846, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=29.0196078431373, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR011285
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25723; Mature: 25723

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRSVLVTGASKGIGQAIACRLAADGFLIAVHYHSDKTGAEHTLQQIISAGGKGRLIQFD
CCCEEEEECCCCCHHHHHHHHEECCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEE
ISNRSQCREVLEQDIETHGAYYGVVNNAGITRDGAFPALSEDDWDGVIHTNLDSFYNVLH
CCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHH
PCVMPMIGLRKGGRIVALSSVSGVMGNRGQVNYSAAKAGVIGACKALAIELAKRKITVNC
HHHHHHHHCCCCCEEEEEECCCHHCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHEEEEEE
IAPGLIDTGMIDMEPAALDEAMRVIPLKRMGSAEEVAGLASYLMSDIAGYVTRQVISING
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GMV
CCC
>Mature Secondary Structure
MMRSVLVTGASKGIGQAIACRLAADGFLIAVHYHSDKTGAEHTLQQIISAGGKGRLIQFD
CCCEEEEECCCCCHHHHHHHHEECCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEE
ISNRSQCREVLEQDIETHGAYYGVVNNAGITRDGAFPALSEDDWDGVIHTNLDSFYNVLH
CCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHH
PCVMPMIGLRKGGRIVALSSVSGVMGNRGQVNYSAAKAGVIGACKALAIELAKRKITVNC
HHHHHHHHCCCCCEEEEEECCCHHCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHEEEEEE
IAPGLIDTGMIDMEPAALDEAMRVIPLKRMGSAEEVAGLASYLMSDIAGYVTRQVISING
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GMV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]