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The map label for this gene is aroF [H]

Identifier: 157369124

GI number: 157369124

Start: 973241

End: 974314

Strand: Direct

Name: aroF [H]

Synonym: Spro_0879

Alternate gene names: 157369124

Gene position: 973241-974314 (Clockwise)

Preceding gene: 157369122

Following gene: 157369125

Centisome position: 17.86

GC content: 56.24

Gene sequence:

>1074_bases
ATGCAAAAAGACGCGCTCAATAACGTTCATATCAGTGCAGAACAAATTCTGATCACTCCGGAAGAACTGAAGAACCAGTT
CCCGCTCAGCGCCAGCGATGAAAATGAAATCGCTACCGCGCGTAAAACCATCGCTGATATTTTGCAGGGGCGCGATCATC
GCCTGCTGGTGGTGTGCGGACCCTGTTCTATCCACGACCCGGATGCTGCCCTGGATTACGCCCGTCATTTGAAAACCCTG
TCGGCTGAATTGAGCGATCAGCTGTATATCGTTATGCGCGTCTATTTTGAAAAACCACGCACCACCGTTGGCTGGAAAGG
CCTGATCAACGATCCGTACATGGACGGTTCGTTTGATGTTGAAGCCGGTTTGCACATCGCGCGTCGTCTGTTGCTGGATC
TGGTAGGTATGGGTCTGCCGTTGGCGACAGAAGCCTTGGATCCGAACAGCCCGCAATACCTGGGTGACCTGTTCAGCTGG
TCGGCGATTGGTGCACGTACCACAGAATCGCAGACTCACCGTGAGATGGCTTCAGGCTTGTCGATGCCGGTGGGCTTCAA
AAACGGCACCGACGGCAGCCTGGGGACGGCAATCAACGCCATGCGTGCCGCGGCGATGCCACACCGTTTTGTCGGCATCA
ACCAGGCAGGGCAAGTGTGCCTGCTGCAAACGCAGGGTAACCCGGATGGGCACGTGATCCTGCGCGGTGGTAAAACGCCG
AACTACAGTGCCGAAGACGTTGCGGCCTGCGAAAAACAGATGCGGGACGCGGGACTCCACCCGTCCTTGATGATAGATTG
CAGCCATGGCAACTCGAATAAAGACTATCGCCGTCAGCCGACGGTTGCCGAGTCCGTGGTAGAGCAGATTAAAGCGGGTA
ACCGTTCGATCACCGGCATCATGCTGGAAAGCCACCTGCACGAAGGCAGCCAGTCTTCTGAACAACCGCGTGCAGATATG
CGCTACGGGGTTTCTGTTACTGACGCCTGCATTAACTGGGAGAGTACCCAGACGCTGCTGCGCCATATGCACCAGGAACT
CGGCACTGCGCTGACGGCACGTACTGGAGAGTAG

Upstream 100 bases:

>100_bases
ATCGGATTTAAAACTTTACATCACATGGTATGGTAAGGACCTGAAACGCTCAAGGTTGTATTAACGCTTACGCATAACGG
CAAACGACAGGAATAGCATC

Downstream 100 bases:

>100_bases
TAAGTTATGGTGGCTGAACTGACCGCGTTACGCGATCAAATTGACGAAGTGGATAAGGCGCTGCTGGAGCTGCTGGCAAA
ACGCCTGCAGCTGGTGGCAG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MQKDALNNVHISAEQILITPEELKNQFPLSASDENEIATARKTIADILQGRDHRLLVVCGPCSIHDPDAALDYARHLKTL
SAELSDQLYIVMRVYFEKPRTTVGWKGLINDPYMDGSFDVEAGLHIARRLLLDLVGMGLPLATEALDPNSPQYLGDLFSW
SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLGTAINAMRAAAMPHRFVGINQAGQVCLLQTQGNPDGHVILRGGKTP
NYSAEDVAACEKQMRDAGLHPSLMIDCSHGNSNKDYRRQPTVAESVVEQIKAGNRSITGIMLESHLHEGSQSSEQPRADM
RYGVSVTDACINWESTQTLLRHMHQELGTALTARTGE

Sequences:

>Translated_357_residues
MQKDALNNVHISAEQILITPEELKNQFPLSASDENEIATARKTIADILQGRDHRLLVVCGPCSIHDPDAALDYARHLKTL
SAELSDQLYIVMRVYFEKPRTTVGWKGLINDPYMDGSFDVEAGLHIARRLLLDLVGMGLPLATEALDPNSPQYLGDLFSW
SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLGTAINAMRAAAMPHRFVGINQAGQVCLLQTQGNPDGHVILRGGKTP
NYSAEDVAACEKQMRDAGLHPSLMIDCSHGNSNKDYRRQPTVAESVVEQIKAGNRSITGIMLESHLHEGSQSSEQPRADM
RYGVSVTDACINWESTQTLLRHMHQELGTALTARTGE
>Mature_357_residues
MQKDALNNVHISAEQILITPEELKNQFPLSASDENEIATARKTIADILQGRDHRLLVVCGPCSIHDPDAALDYARHLKTL
SAELSDQLYIVMRVYFEKPRTTVGWKGLINDPYMDGSFDVEAGLHIARRLLLDLVGMGLPLATEALDPNSPQYLGDLFSW
SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLGTAINAMRAAAMPHRFVGINQAGQVCLLQTQGNPDGHVILRGGKTP
NYSAEDVAACEKQMRDAGLHPSLMIDCSHGNSNKDYRRQPTVAESVVEQIKAGNRSITGIMLESHLHEGSQSSEQPRADM
RYGVSVTDACINWESTQTLLRHMHQELGTALTARTGE

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=356, Percent_Identity=80.3370786516854, Blast_Score=612, Evalue=1e-176,
Organism=Escherichia coli, GI1786969, Length=350, Percent_Identity=55.1428571428571, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1787996, Length=340, Percent_Identity=49.7058823529412, Blast_Score=340, Evalue=7e-95,
Organism=Saccharomyces cerevisiae, GI6320240, Length=342, Percent_Identity=52.3391812865497, Blast_Score=362, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6319726, Length=345, Percent_Identity=51.0144927536232, Blast_Score=347, Evalue=2e-96,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39012; Mature: 39012

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKDALNNVHISAEQILITPEELKNQFPLSASDENEIATARKTIADILQGRDHRLLVVCG
CCCCCCCCEEEECCEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEC
PCSIHDPDAALDYARHLKTLSAELSDQLYIVMRVYFEKPRTTVGWKGLINDPYMDGSFDV
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCH
EAGLHIARRLLLDLVGMGLPLATEALDPNSPQYLGDLFSWSAIGARTTESQTHREMASGL
HHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
SMPVGFKNGTDGSLGTAINAMRAAAMPHRFVGINQAGQVCLLQTQGNPDGHVILRGGKTP
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHEECCCCCCCEEEEEECCCCCCEEEEECCCCC
NYSAEDVAACEKQMRDAGLHPSLMIDCSHGNSNKDYRRQPTVAESVVEQIKAGNRSITGI
CCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEE
MLESHLHEGSQSSEQPRADMRYGVSVTDACINWESTQTLLRHMHQELGTALTARTGE
EHHHHHCCCCCCCCCCCHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQKDALNNVHISAEQILITPEELKNQFPLSASDENEIATARKTIADILQGRDHRLLVVCG
CCCCCCCCEEEECCEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEC
PCSIHDPDAALDYARHLKTLSAELSDQLYIVMRVYFEKPRTTVGWKGLINDPYMDGSFDV
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCH
EAGLHIARRLLLDLVGMGLPLATEALDPNSPQYLGDLFSWSAIGARTTESQTHREMASGL
HHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
SMPVGFKNGTDGSLGTAINAMRAAAMPHRFVGINQAGQVCLLQTQGNPDGHVILRGGKTP
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHEECCCCCCCEEEEEECCCCCCEEEEECCCCC
NYSAEDVAACEKQMRDAGLHPSLMIDCSHGNSNKDYRRQPTVAESVVEQIKAGNRSITGI
CCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEE
MLESHLHEGSQSSEQPRADMRYGVSVTDACINWESTQTLLRHMHQELGTALTARTGE
EHHHHHCCCCCCCCCCCHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]