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The map label for this gene is cysC [H]

Identifier: 157369065

GI number: 157369065

Start: 916053

End: 916682

Strand: Direct

Name: cysC [H]

Synonym: Spro_0820

Alternate gene names: 157369065

Gene position: 916053-916682 (Clockwise)

Preceding gene: 157369064

Following gene: 157369066

Centisome position: 16.81

GC content: 57.78

Gene sequence:

>630_bases
GTGGCCGACGTAGAGCAACGACCCACCGGGCCGGATGATGACAACGTGGTCTGGCATCCGCATGCGGTAGCGCGTGCGGA
TCGCGAAGCCCGTAATGGCCATAAAGGCGTGGTGCTGTGGTTTACCGGGCTGTCCGGCTCGGGTAAATCCACCGTTGCCG
GTGCGCTGGAGCAGGCGCTGCACGCCCTTGGCGTCAGCACCTATTTGCTGGATGGCGATAACGTGCGTCACGGCCTGTGC
CGCGATCTGGGATTCTCAGATGACGATCGGCGCGAGAATATTCGCCGCGTGGGTGAAGTGTCCAAACTGATGGTAGATGC
CGGGCTAGTGGTGCTGACCGCGTTTATTTCACCGCACCGCACAGAACGGCAGATGGTGCGCGAACTGCTTGATGAAGAGC
GCTTTATCGAGGTGTTTGTCGACACGCCACTGGCGATTTGTGAGCAGCGCGATCCGAAGGGGTTGTACAAAAAAGCCCGG
GCCGGGGAACTGCGTAATTTCACCGGAATTGACTCGGTTTACGAGGCTCCGCAACGGCCGGATATTCACCTTGATGGCCA
ACAATTGGTAACAAATTTGATTGCGCAATTGTTAGACGTGCTGCGTGGTCGGGCTATTATCAAACCCTGA

Upstream 100 bases:

>100_bases
GCCACTGGTGACTTCAGCGCATTCGAGCTGGAACTGAATGCTTTGGTGCGTAAACACTTCCCGCATTGGGGCGCACGCGA
CCTGATCGGGGGCAAGTAAC

Downstream 100 bases:

>100_bases
ATTCAGAAAAGCGTGTGGCGTTTTTGCGCCATACGCTTTTTACGCTAAGCCCGCCGGAGAGCGTGCCGAATAACCAGGGA
TCACTATGCAAAATGTCTCG

Product: adenylyl-sulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MADVEQRPTGPDDDNVVWHPHAVARADREARNGHKGVVLWFTGLSGSGKSTVAGALEQALHALGVSTYLLDGDNVRHGLC
RDLGFSDDDRRENIRRVGEVSKLMVDAGLVVLTAFISPHRTERQMVRELLDEERFIEVFVDTPLAICEQRDPKGLYKKAR
AGELRNFTGIDSVYEAPQRPDIHLDGQQLVTNLIAQLLDVLRGRAIIKP

Sequences:

>Translated_209_residues
MADVEQRPTGPDDDNVVWHPHAVARADREARNGHKGVVLWFTGLSGSGKSTVAGALEQALHALGVSTYLLDGDNVRHGLC
RDLGFSDDDRRENIRRVGEVSKLMVDAGLVVLTAFISPHRTERQMVRELLDEERFIEVFVDTPLAICEQRDPKGLYKKAR
AGELRNFTGIDSVYEAPQRPDIHLDGQQLVTNLIAQLLDVLRGRAIIKP
>Mature_208_residues
ADVEQRPTGPDDDNVVWHPHAVARADREARNGHKGVVLWFTGLSGSGKSTVAGALEQALHALGVSTYLLDGDNVRHGLCR
DLGFSDDDRRENIRRVGEVSKLMVDAGLVVLTAFISPHRTERQMVRELLDEERFIEVFVDTPLAICEQRDPKGLYKKARA
GELRNFTGIDSVYEAPQRPDIHLDGQQLVTNLIAQLLDVLRGRAIIKP

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=200, Percent_Identity=49.5, Blast_Score=197, Evalue=4e-51,
Organism=Homo sapiens, GI62912492, Length=200, Percent_Identity=49.5, Blast_Score=193, Evalue=8e-50,
Organism=Homo sapiens, GI34447231, Length=200, Percent_Identity=49.5, Blast_Score=193, Evalue=9e-50,
Organism=Escherichia coli, GI1789107, Length=197, Percent_Identity=80.2030456852792, Blast_Score=326, Evalue=5e-91,
Organism=Caenorhabditis elegans, GI17542422, Length=200, Percent_Identity=50, Blast_Score=207, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6322852, Length=197, Percent_Identity=50.761421319797, Blast_Score=201, Evalue=9e-53,
Organism=Drosophila melanogaster, GI24667032, Length=174, Percent_Identity=48.8505747126437, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24667028, Length=174, Percent_Identity=48.8505747126437, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24667036, Length=174, Percent_Identity=48.8505747126437, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24667040, Length=200, Percent_Identity=45, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI116007838, Length=200, Percent_Identity=45, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24667044, Length=200, Percent_Identity=45, Blast_Score=171, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 23239; Mature: 23107

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVEQRPTGPDDDNVVWHPHAVARADREARNGHKGVVLWFTGLSGSGKSTVAGALEQAL
CCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHH
HALGVSTYLLDGDNVRHGLCRDLGFSDDDRRENIRRVGEVSKLMVDAGLVVLTAFISPHR
HHHHHHHEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TERQMVRELLDEERFIEVFVDTPLAICEQRDPKGLYKKARAGELRNFTGIDSVYEAPQRP
HHHHHHHHHHCHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHCCCCC
DIHLDGQQLVTNLIAQLLDVLRGRAIIKP
CCEECHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ADVEQRPTGPDDDNVVWHPHAVARADREARNGHKGVVLWFTGLSGSGKSTVAGALEQAL
CCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHH
HALGVSTYLLDGDNVRHGLCRDLGFSDDDRRENIRRVGEVSKLMVDAGLVVLTAFISPHR
HHHHHHHEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TERQMVRELLDEERFIEVFVDTPLAICEQRDPKGLYKKARAGELRNFTGIDSVYEAPQRP
HHHHHHHHHHCHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHCCCCC
DIHLDGQQLVTNLIAQLLDVLRGRAIIKP
CCEECHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]